JPS51146295A - Method* composition and substance for analyzing specific bonding in uniform system - Google Patents

Method* composition and substance for analyzing specific bonding in uniform system

Info

Publication number
JPS51146295A
JPS51146295A JP51047347A JP4734776A JPS51146295A JP S51146295 A JPS51146295 A JP S51146295A JP 51047347 A JP51047347 A JP 51047347A JP 4734776 A JP4734776 A JP 4734776A JP S51146295 A JPS51146295 A JP S51146295A
Authority
JP
Japan
Prior art keywords
substance
composition
specific bonding
uniform system
analyzing specific
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP51047347A
Other languages
English (en)
Other versions
JPS604939B2 (ja
Inventor
Chiyaarusu Bogusurasuk Robaato
Jiyosefu Kariko Robaato
Edowaado Kurisutonaa Jieemusu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Miles Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Laboratories Inc filed Critical Miles Laboratories Inc
Publication of JPS51146295A publication Critical patent/JPS51146295A/ja
Publication of JPS604939B2 publication Critical patent/JPS604939B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
JP51047347A 1975-04-28 1976-04-27 液体中のハプテンヌは抗原を分析するための均一系免疫分析方法及びそれに用いる試薬 Expired JPS604939B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57200875A 1975-04-28 1975-04-28
US572008 2000-05-16

Publications (2)

Publication Number Publication Date
JPS51146295A true JPS51146295A (en) 1976-12-15
JPS604939B2 JPS604939B2 (ja) 1985-02-07

Family

ID=24285954

Family Applications (6)

Application Number Title Priority Date Filing Date
JP51047347A Expired JPS604939B2 (ja) 1975-04-28 1976-04-27 液体中のハプテンヌは抗原を分析するための均一系免疫分析方法及びそれに用いる試薬
JP51047348A Expired JPS6052378B2 (ja) 1975-04-28 1976-04-27 液体中のハプテン又は抗原を分析するための不均一系免疫分析方法及び試薬
JP58122466A Granted JPS5951354A (ja) 1975-04-28 1983-07-07 液体中のハプテン又は抗原を分析するための不均一系免疫分析方法及び試薬
JP58122464A Granted JPS5942454A (ja) 1975-04-28 1983-07-07 液体中のハプテン又は抗原を分析するための均一系免疫分析方法及び試薬
JP58122463A Granted JPS5942453A (ja) 1975-04-28 1983-07-07 液体中のハプテン又は抗原を分析するための均一系免疫分析方法及び試薬
JP58122465A Granted JPS5951353A (ja) 1975-04-28 1983-07-07 液体中のハプテン又は抗原を分析するための不均一系免疫分析方法及び試薬

Family Applications After (5)

Application Number Title Priority Date Filing Date
JP51047348A Expired JPS6052378B2 (ja) 1975-04-28 1976-04-27 液体中のハプテン又は抗原を分析するための不均一系免疫分析方法及び試薬
JP58122466A Granted JPS5951354A (ja) 1975-04-28 1983-07-07 液体中のハプテン又は抗原を分析するための不均一系免疫分析方法及び試薬
JP58122464A Granted JPS5942454A (ja) 1975-04-28 1983-07-07 液体中のハプテン又は抗原を分析するための均一系免疫分析方法及び試薬
JP58122463A Granted JPS5942453A (ja) 1975-04-28 1983-07-07 液体中のハプテン又は抗原を分析するための均一系免疫分析方法及び試薬
JP58122465A Granted JPS5951353A (ja) 1975-04-28 1983-07-07 液体中のハプテン又は抗原を分析するための不均一系免疫分析方法及び試薬

Country Status (23)

Country Link
JP (6) JPS604939B2 (ja)
AT (1) AT357685B (ja)
AU (2) AU509182B2 (ja)
BE (1) BE841179A (ja)
BR (1) BR7602561A (ja)
CA (2) CA1082577A (ja)
CH (1) CH635438A5 (ja)
DD (1) DD125231A5 (ja)
DE (3) DE2618511C3 (ja)
DK (3) DK149969C (ja)
ES (1) ES447378A1 (ja)
FI (1) FI68324C (ja)
FR (1) FR2332533A1 (ja)
GB (2) GB1548741A (ja)
HU (1) HU179542B (ja)
IE (1) IE42544B1 (ja)
IL (1) IL49354A (ja)
IN (1) IN142734B (ja)
IT (1) IT1064132B (ja)
LU (1) LU74834A1 (ja)
NL (1) NL181281C (ja)
SE (3) SE440280B (ja)
ZA (1) ZA762030B (ja)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5678599A (en) * 1979-10-29 1981-06-27 List Hans Analysis of substance concentration in solution
JPS5692218A (en) * 1979-12-26 1981-07-25 Syva Co Immunoassay
JPS57103055A (en) * 1980-10-30 1982-06-26 Miles Lab Analysis of homogeneous peculiar bond and apparatus used therefor
JPS57209297A (en) * 1981-04-17 1982-12-22 Univ Yale Modified nucleotide, manufacture and use
JPS5818167A (ja) * 1981-07-24 1983-02-02 Fuji Photo Film Co Ltd 分析フイルム及びこれを用いる分析方法
JPS5877843U (ja) * 1981-11-20 1983-05-26 株式会社三協精機製作所 テ−プレコ−ダ
JPS58176550A (ja) * 1982-03-18 1983-10-17 マイルス・ラボラトリ−ズ・インコ−ポレ−テツド 均一系免疫試験法、それに用いる試薬調製物及び試薬系
JPS58502206A (ja) * 1981-12-29 1983-12-22 アンステイテユ・パストウ−ル 修飾されたアデノシン５′−トリリン酸及び該アデノシン５′−トリリン酸の減成生成物を固定し得る生物学的物質の定量法
JPS5962600A (ja) * 1982-06-23 1984-04-10 エンゾ・バイオケム・インコ−ポレ−テツド 修飾ヌクレオチド
JP2015192635A (ja) * 2014-03-31 2015-11-05 シスメックス株式会社 キナーゼ活性の測定方法

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL51668A (en) 1977-03-16 1981-12-31 Israel State Analytical method for the quantitative determination of immunogens and antibodies and a kit therefor
SE7811630L (sv) * 1977-11-17 1979-05-18 Welsh Nat School Med Metod for uppteckt eller mengdbestemning av substanser med anvendning av merkningsteknik
USRE34394E (en) * 1978-01-23 1993-09-28 Baxter Diagnostics Inc. Method and composition for double receptor, specific binding assays
AU531777B2 (en) * 1978-04-05 1983-09-08 Syva Co. Label/solid conjugate immunoassay system
US4233402A (en) * 1978-04-05 1980-11-11 Syva Company Reagents and method employing channeling
US5605800A (en) * 1978-04-13 1997-02-25 Institut Pasteur Method of detecting and characterizing a nucleic acid or a sequence of the latter, and enzymatic reactant for the application of this method
FR2422956A1 (fr) * 1978-04-13 1979-11-09 Pasteur Institut Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede
DE2924249C2 (de) * 1978-06-22 1989-04-27 Miles, Inc., Elkhart, Ind., Us Spezifische bindungs-untersuchungsmethode zur bestimmung eines liganden in einem fluessigen medium und reagentien zur durchfuehrung dieser methode
DE2924332A1 (de) * 1978-06-22 1980-01-03 Miles Lab Flavin-adenin-dinukleotid-markiertes konjugat und dessen verwendung in spezifischen bindungsversuchen
US4334069A (en) * 1978-07-24 1982-06-08 Miles Laboratories, Inc. Chemiluminescent phthalhydrazide-labeled hapten conjugates
US4225485A (en) * 1978-07-24 1980-09-30 Miles Laboratories, Inc. Chemiluminescent naphthalene-1,2-dicarboxylic acid hydrazide-labeled polypeptides and proteins
US4228237A (en) * 1978-09-21 1980-10-14 Calbiochem-Behring Corp. Methods for the detection and determination of ligands
US4288538A (en) 1979-01-31 1981-09-08 Baxter Travenol Laboratories, Inc. Test method and composition therefor
US4273866A (en) * 1979-02-05 1981-06-16 Abbott Laboratories Ligand analog-irreversible enzyme inhibitor conjugates and methods for use
US4446231A (en) * 1979-10-03 1984-05-01 Self Colin H Immunoassay using an amplified cyclic detection system
GB2059421A (en) * 1979-10-03 1981-04-23 Self C H Assay method and reagents therefor
US4259232A (en) * 1979-10-23 1981-03-31 Miles Laboratories, Inc. Flavin adenine dinucleotide-labeled protein and polypeptide conjugates
EP0040224A4 (en) * 1979-11-19 1982-09-09 Prince Charles Hospital Dev Ct IMPROVED PROCESS FOR IMMUNOLOGICAL ANALYSIS OF NON-HOMOGENOUS ENZYMES.
DK256581A (da) * 1980-06-13 1981-12-14 Nat Res Dev Bindingsanalyse
EP0049606A1 (en) * 1980-10-02 1982-04-14 Colin Henry Self Detection method, use and diagnostic aid
US4404278A (en) * 1980-11-24 1983-09-13 Syva Company Methods and compositions for assaying for the production of 1,4-dihydropyridyl
US4378458A (en) * 1981-03-30 1983-03-29 Baker Instruments Corporation Novel chromogenic and/or fluorogenic substrates for monitoring catalytic or enzymatic activity
US4366243A (en) 1981-04-17 1982-12-28 Miles Laboratories, Inc. Stabilization of glucose oxidase apoenzyme
ATE48140T1 (de) * 1981-04-17 1989-12-15 Univ Yale Modifizierte nukleotide und verfahren zu ihrer herstellung und anwendung.
US4711955A (en) * 1981-04-17 1987-12-08 Yale University Modified nucleotides and methods of preparing and using same
EP0082636B2 (en) * 1981-12-11 2006-10-18 The Welsh National School of Medicine Luminescent labelling materials and procedures
FR2519005B1 (fr) * 1981-12-29 1985-10-25 Pasteur Institut Fragments d'adn marques a l'une au moins de leurs extremites par des ribonucleotides modifies reconnaissables par des molecules affines et procede pour realiser une analyse de tels fragments d'adn
US4709016A (en) * 1982-02-01 1987-11-24 Northeastern University Molecular analytical release tags and their use in chemical analysis
US5650270A (en) * 1982-02-01 1997-07-22 Northeastern University Molecular analytical release tags and their use in chemical analysis
US4495281A (en) * 1982-10-21 1985-01-22 Miles Laboratories, Inc. Tricyclic antidepressant drug immunogens, antibodies, labeled conjugates, and related derivatives
US4994373A (en) 1983-01-27 1991-02-19 Enzo Biochem, Inc. Method and structures employing chemically-labelled polynucleotide probes
US4828979A (en) * 1984-11-08 1989-05-09 Life Technologies, Inc. Nucleotide analogs for nucleic acid labeling and detection
EP0201211A1 (en) * 1985-04-10 1986-11-12 Whittaker Corporation Method and compositions for visual solid phase immunoassays based on luminescent microspheric particles
JPS61271457A (ja) * 1985-05-28 1986-12-01 Olympus Optical Co Ltd 免疫学的分析方法
JPH06100599B2 (ja) * 1985-06-27 1994-12-12 東亜医用電子株式会社 体液成分の測定方法
JPS6321559A (ja) * 1986-07-16 1988-01-29 Matsushita Electric Ind Co Ltd ハプテンの酵素免疫測定法
US6002007A (en) * 1988-02-20 1999-12-14 Dade Behring Marburg Gmbh Special chemiluminescent acridine derivatives and the use thereof in luminescence immunoassays
DE3844954C2 (de) * 1988-02-20 1998-07-16 Hoechst Ag Spezielle chemilumineszierende Acridinderivate und ihre Verwendung in Lumineszenzimmunoassays
JP2525678B2 (ja) * 1989-10-03 1996-08-21 富士写真フイルム株式会社 免疫測定装置
US6596490B2 (en) 2000-07-14 2003-07-22 Applied Gene Technologies, Inc. Nucleic acid hairpin probes and uses thereof
US6380377B1 (en) 2000-07-14 2002-04-30 Applied Gene Technologies, Inc. Nucleic acid hairpin probes and uses thereof
CN100494399C (zh) 2003-06-30 2009-06-03 清华大学 一种基于dna芯片的基因分型方法及其应用
US7732153B2 (en) 2006-05-09 2010-06-08 Beckman Coulter, Inc. Nonseparation assay methods
US7799534B2 (en) 2006-05-09 2010-09-21 Beckman Coulter, Inc. Nonseparation assay methods

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5147348A (ja) * 1974-10-21 1976-04-22 Nippon Electric Co Johoshorisochi

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154600B (nl) * 1971-02-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen.
US3817837A (en) * 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3880934A (en) * 1972-02-10 1975-04-29 Syntex Inc Nitrophenyloxy-butanediols
JPS5147347A (ja) * 1974-10-21 1976-04-22 Nippon Electric Co Johoshorisochi

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5147348A (ja) * 1974-10-21 1976-04-22 Nippon Electric Co Johoshorisochi

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5678599A (en) * 1979-10-29 1981-06-27 List Hans Analysis of substance concentration in solution
JPS5692218A (en) * 1979-12-26 1981-07-25 Syva Co Immunoassay
JPS57103055A (en) * 1980-10-30 1982-06-26 Miles Lab Analysis of homogeneous peculiar bond and apparatus used therefor
JPS57209297A (en) * 1981-04-17 1982-12-22 Univ Yale Modified nucleotide, manufacture and use
JPS5818167A (ja) * 1981-07-24 1983-02-02 Fuji Photo Film Co Ltd 分析フイルム及びこれを用いる分析方法
JPS5877843U (ja) * 1981-11-20 1983-05-26 株式会社三協精機製作所 テ−プレコ−ダ
JPS58502206A (ja) * 1981-12-29 1983-12-22 アンステイテユ・パストウ−ル 修飾されたアデノシン５′−トリリン酸及び該アデノシン５′−トリリン酸の減成生成物を固定し得る生物学的物質の定量法
JPS58176550A (ja) * 1982-03-18 1983-10-17 マイルス・ラボラトリ−ズ・インコ−ポレ−テツド 均一系免疫試験法、それに用いる試薬調製物及び試薬系
JPS5962600A (ja) * 1982-06-23 1984-04-10 エンゾ・バイオケム・インコ−ポレ−テツド 修飾ヌクレオチド
JP2015192635A (ja) * 2014-03-31 2015-11-05 シスメックス株式会社 キナーゼ活性の測定方法

Also Published As

Publication number Publication date
DE2660548C2 (de) 1984-04-12
CA1078712A (en) 1980-06-03
FI761148A7 (ja) 1976-10-29
FR2332533A1 (fr) 1977-06-17
NL181281B (nl) 1987-02-16
GB1548741A (en) 1979-07-18
SE451895B (sv) 1987-11-02
JPS5951354A (ja) 1984-03-24
JPS5942454A (ja) 1984-03-09
DE2618511C3 (de) 1981-05-07
JPH0137694B2 (ja) 1989-08-09
GB1552607A (en) 1979-09-19
DK149969B (da) 1986-11-03
DD125231A5 (ja) 1977-04-06
DE2618419C2 (de) 1983-02-10
DK149969C (da) 1988-08-01
SE8007396L (sv) 1980-10-21
DK158366B (da) 1990-05-07
IE42544L (en) 1976-10-28
AU1335376A (en) 1977-11-03
DE2618511B2 (de) 1980-08-14
AU502726B2 (en) 1979-08-09
NL7604420A (nl) 1976-11-01
DK158366C (da) 1990-10-01
JPH0145026B2 (ja) 1989-10-02
SE440280B (sv) 1985-07-22
DK576281A (da) 1981-12-23
ZA762030B (en) 1977-08-31
AU1335276A (en) 1977-11-03
SE8007397L (sv) 1980-10-21
DK189176A (da) 1976-10-29
FI68324B (fi) 1985-04-30
AT357685B (de) 1980-07-25
CA1082577A (en) 1980-07-29
BR7602561A (pt) 1976-11-23
IE42544B1 (en) 1980-08-27
FI68324C (fi) 1985-08-12
HU179542B (en) 1982-11-29
IT1064132B (it) 1985-02-18
IL49354A0 (en) 1976-06-30
ATA309376A (de) 1979-12-15
LU74834A1 (ja) 1977-01-12
SE447510B (sv) 1986-11-17
JPS604939B2 (ja) 1985-02-07
SE7604841L (sv) 1976-10-29
ES447378A1 (es) 1977-11-01
JPH0145027B2 (ja) 1989-10-02
JPH0137693B2 (ja) 1989-08-09
NL181281C (nl) 1987-07-16
DE2618419A1 (de) 1976-11-04
AU509182B2 (en) 1980-04-24
JPS6052378B2 (ja) 1985-11-19
FR2332533B1 (ja) 1981-12-18
JPS5942453A (ja) 1984-03-09
CH635438A5 (en) 1983-03-31
IL49354A (en) 1979-03-12
DE2618511A1 (de) 1976-11-04
DK576181A (da) 1981-12-23
BE841179A (fr) 1976-08-16
IN142734B (ja) 1977-08-20
JPS5267388A (en) 1977-06-03
DK150808B (da) 1987-06-22
JPS5951353A (ja) 1984-03-24
DK150808C (da) 1988-02-15

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