JPS58890A - ウロキナ−ゼの回収法 - Google Patents
ウロキナ−ゼの回収法Info
- Publication number
- JPS58890A JPS58890A JP9833881A JP9833881A JPS58890A JP S58890 A JPS58890 A JP S58890A JP 9833881 A JP9833881 A JP 9833881A JP 9833881 A JP9833881 A JP 9833881A JP S58890 A JPS58890 A JP S58890A
- Authority
- JP
- Japan
- Prior art keywords
- urokinase
- perlite
- washed
- aqueous solution
- urine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000003990 Urokinase-type plasminogen activator Human genes 0.000 title claims abstract description 45
- 108090000435 Urokinase-type plasminogen activator Proteins 0.000 title claims abstract description 45
- 229960005356 urokinase Drugs 0.000 title claims abstract description 45
- 238000011084 recovery Methods 0.000 title 1
- 210000002700 urine Anatomy 0.000 claims abstract description 20
- 239000000243 solution Substances 0.000 claims abstract description 13
- 239000010451 perlite Substances 0.000 claims abstract description 12
- 235000019362 perlite Nutrition 0.000 claims abstract description 12
- 238000000034 method Methods 0.000 claims description 19
- 238000001179 sorption measurement Methods 0.000 claims description 12
- 229910001562 pearlite Inorganic materials 0.000 claims description 7
- 239000012266 salt solution Substances 0.000 claims description 3
- 239000000428 dust Substances 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 abstract description 13
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 abstract description 6
- VEXZGXHMUGYJMC-UHFFFAOYSA-N hydrochloric acid Substances Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract description 4
- 150000003839 salts Chemical class 0.000 abstract description 4
- 239000003513 alkali Substances 0.000 abstract 1
- 235000011114 ammonium hydroxide Nutrition 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 16
- 102000004169 proteins and genes Human genes 0.000 description 10
- 108090000623 proteins and genes Proteins 0.000 description 10
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 7
- 230000000694 effects Effects 0.000 description 7
- 238000010828 elution Methods 0.000 description 6
- 239000012153 distilled water Substances 0.000 description 5
- 238000005187 foaming Methods 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- 241000209219 Hordeum Species 0.000 description 4
- 235000007340 Hordeum vulgare Nutrition 0.000 description 4
- 239000003463 adsorbent Substances 0.000 description 4
- 239000007788 liquid Substances 0.000 description 3
- 239000002244 precipitate Substances 0.000 description 3
- 239000011780 sodium chloride Substances 0.000 description 3
- 238000005406 washing Methods 0.000 description 3
- 102000009123 Fibrin Human genes 0.000 description 2
- 108010073385 Fibrin Proteins 0.000 description 2
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 description 2
- -1 Hyfloss-Barcel Chemical compound 0.000 description 2
- TZCXTZWJZNENPQ-UHFFFAOYSA-L barium sulfate Chemical compound [Ba+2].[O-]S([O-])(=O)=O TZCXTZWJZNENPQ-UHFFFAOYSA-L 0.000 description 2
- 229950003499 fibrin Drugs 0.000 description 2
- 206010014523 Embolism and thrombosis Diseases 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 241001529936 Murinae Species 0.000 description 1
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical group [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 102000013566 Plasminogen Human genes 0.000 description 1
- 108010051456 Plasminogen Proteins 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 229910021536 Zeolite Inorganic materials 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- KFVBMBOOLFSJHV-UHFFFAOYSA-K aluminum;sodium;hexane-1,2,3,4,5,6-hexol;carbonate;hydroxide Chemical compound [OH-].[Na+].[Al+3].[O-]C([O-])=O.OCC(O)C(O)C(O)C(O)CO KFVBMBOOLFSJHV-UHFFFAOYSA-K 0.000 description 1
- 239000002246 antineoplastic agent Substances 0.000 description 1
- 229940041181 antineoplastic drug Drugs 0.000 description 1
- 239000000440 bentonite Substances 0.000 description 1
- 229910000278 bentonite Inorganic materials 0.000 description 1
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 description 1
- 229940088598 enzyme Drugs 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 229940012957 plasmin Drugs 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 239000011435 rock Substances 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 210000004885 white matter Anatomy 0.000 description 1
- 239000010457 zeolite Substances 0.000 description 1
Landscapes
- Enzymes And Modification Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9833881A JPS58890A (ja) | 1981-06-26 | 1981-06-26 | ウロキナ−ゼの回収法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9833881A JPS58890A (ja) | 1981-06-26 | 1981-06-26 | ウロキナ−ゼの回収法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS58890A true JPS58890A (ja) | 1983-01-06 |
| JPH0143550B2 JPH0143550B2 (de) | 1989-09-21 |
Family
ID=14217111
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9833881A Granted JPS58890A (ja) | 1981-06-26 | 1981-06-26 | ウロキナ−ゼの回収法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS58890A (de) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4710043A (en) * | 1985-04-18 | 1987-12-01 | Tokyo Electric Co., Ltd. | Impact printer with variable delay for print cycle based on different print-hammer energy levels |
-
1981
- 1981-06-26 JP JP9833881A patent/JPS58890A/ja active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4710043A (en) * | 1985-04-18 | 1987-12-01 | Tokyo Electric Co., Ltd. | Impact printer with variable delay for print cycle based on different print-hammer energy levels |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0143550B2 (de) | 1989-09-21 |
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