JPS6058154A - 薬物治療システム用生体端子 - Google Patents

薬物治療システム用生体端子

Info

Publication number: JPS6058154A
Authority: JP; Japan
Prior art keywords: terminal; skin; sintered; drug; porous
Prior art date: 1983-09-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

JP58166502A

Other languages

English (en)

Japanese (ja)

Other versions

JPH0150416B2 (fr

Inventor

秀希青木

赤尾　勝

美治秦

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Advance Kaihatsu Kenkyujo KK

Original Assignee

Advance Kaihatsu Kenkyujo KK

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-09-12

Filing date

1983-09-12

Publication date

1985-04-04

1983-09-12 Application filed by Advance Kaihatsu Kenkyujo KK filed Critical Advance Kaihatsu Kenkyujo KK

1983-09-12 Priority to JP58166502A priority Critical patent/JPS6058154A/ja

1984-03-21 Priority to CA000450058A priority patent/CA1247960A/fr

1984-03-23 Priority to DE8484301977T priority patent/DE3482893D1/de

1984-03-23 Priority to EP84301977A priority patent/EP0120689B1/fr

1985-04-04 Publication of JPS6058154A publication Critical patent/JPS6058154A/ja

1989-10-30 Publication of JPH0150416B2 publication Critical patent/JPH0150416B2/ja

1990-09-05 Priority to US07/577,820 priority patent/US5035711A/en

1990-09-10 Priority to US07/581,122 priority patent/US5026397A/en

Status Granted legal-status Critical Current

Links

239000003814 drug Substances 0.000 title description 17
229940079593 drug Drugs 0.000 title description 17
239000000463 material Substances 0.000 claims description 15
229910052586 apatite Inorganic materials 0.000 claims description 5
VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 claims description 5
239000012530 fluid Substances 0.000 claims description 2
239000002689 soil Substances 0.000 claims 1
210000003491 skin Anatomy 0.000 description 16
210000001519 tissue Anatomy 0.000 description 10
229910052588 hydroxylapatite Inorganic materials 0.000 description 8
238000002347 injection Methods 0.000 description 8
239000007924 injection Substances 0.000 description 8
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 8
XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 8
239000010410 layer Substances 0.000 description 7
239000011148 porous material Substances 0.000 description 7
239000011347 resin Substances 0.000 description 7
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239000012528 membrane Substances 0.000 description 6
229910052751 metal Inorganic materials 0.000 description 5
239000002184 metal Substances 0.000 description 5
238000000034 method Methods 0.000 description 5
239000000843 powder Substances 0.000 description 5
102000004877 Insulin Human genes 0.000 description 4
108090001061 Insulin Proteins 0.000 description 4
239000011575 calcium Substances 0.000 description 4
-1 chlorine ions Chemical class 0.000 description 4
229940125396 insulin Drugs 0.000 description 4
239000000203 mixture Substances 0.000 description 4
239000000243 solution Substances 0.000 description 4
239000000126 substance Substances 0.000 description 4
229910019142 PO4 Inorganic materials 0.000 description 3
PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 3
238000001914 filtration Methods 0.000 description 3
238000004519 manufacturing process Methods 0.000 description 3
229920001296 polysiloxane Polymers 0.000 description 3
238000005245 sintering Methods 0.000 description 3
210000000434 stratum corneum Anatomy 0.000 description 3
239000002023 wood Substances 0.000 description 3
229910001369 Brass Inorganic materials 0.000 description 2
BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 2
208000001836 Firesetting Behavior Diseases 0.000 description 2
206010061218 Inflammation Diseases 0.000 description 2
NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
239000004698 Polyethylene Substances 0.000 description 2
MCMNRKCIXSYSNV-UHFFFAOYSA-N Zirconium dioxide Chemical compound O=[Zr]=O MCMNRKCIXSYSNV-UHFFFAOYSA-N 0.000 description 2
239000000654 additive Substances 0.000 description 2
239000010951 brass Substances 0.000 description 2
150000001768 cations Chemical class 0.000 description 2
230000006835 compression Effects 0.000 description 2
238000007906 compression Methods 0.000 description 2
239000004020 conductor Substances 0.000 description 2
238000011161 development Methods 0.000 description 2
238000000502 dialysis Methods 0.000 description 2
238000009792 diffusion process Methods 0.000 description 2
238000012377 drug delivery Methods 0.000 description 2
238000005370 electroosmosis Methods 0.000 description 2
239000007943 implant Substances 0.000 description 2
230000004054 inflammatory process Effects 0.000 description 2
150000002500 ions Chemical class 0.000 description 2
239000007788 liquid Substances 0.000 description 2
150000002739 metals Chemical class 0.000 description 2
210000000496 pancreas Anatomy 0.000 description 2
BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
229920002492 poly(sulfone) Polymers 0.000 description 2
239000004417 polycarbonate Substances 0.000 description 2
229920000515 polycarbonate Polymers 0.000 description 2
229920000573 polyethylene Polymers 0.000 description 2
229920000642 polymer Polymers 0.000 description 2
229920003002 synthetic resin Polymers 0.000 description 2
239000000057 synthetic resin Substances 0.000 description 2
238000000108 ultra-filtration Methods 0.000 description 2
208000035143 Bacterial infection Diseases 0.000 description 1
239000004641 Diallyl-phthalate Substances 0.000 description 1
239000004593 Epoxy Substances 0.000 description 1
KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 description 1
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
229910017771 LaFeO Inorganic materials 0.000 description 1
CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 description 1
108010067035 Pancrelipase Proteins 0.000 description 1
239000004743 Polypropylene Substances 0.000 description 1
241001115903 Raphus cucullatus Species 0.000 description 1
239000004809 Teflon Substances 0.000 description 1
229920006362 Teflon® Polymers 0.000 description 1
230000002159 abnormal effect Effects 0.000 description 1
230000000996 additive effect Effects 0.000 description 1
239000000853 adhesive Substances 0.000 description 1
230000001070 adhesive effect Effects 0.000 description 1
229910000147 aluminium phosphate Inorganic materials 0.000 description 1
238000013459 approach Methods 0.000 description 1
208000022362 bacterial infectious disease Diseases 0.000 description 1
238000005452 bending Methods 0.000 description 1
230000015572 biosynthetic process Effects 0.000 description 1
QUDWYFHPNIMBFC-UHFFFAOYSA-N bis(prop-2-enyl) benzene-1,2-dicarboxylate Chemical compound C=CCOC(=O)C1=CC=CC=C1C(=O)OCC=C QUDWYFHPNIMBFC-UHFFFAOYSA-N 0.000 description 1
230000000740 bleeding effect Effects 0.000 description 1
239000008280 blood Substances 0.000 description 1
210000004369 blood Anatomy 0.000 description 1
210000000988 bone and bone Anatomy 0.000 description 1
AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 description 1
239000000920 calcium hydroxide Substances 0.000 description 1
229910001861 calcium hydroxide Inorganic materials 0.000 description 1
239000001506 calcium phosphate Substances 0.000 description 1
229910000389 calcium phosphate Inorganic materials 0.000 description 1
235000011010 calcium phosphates Nutrition 0.000 description 1
229920002301 cellulose acetate Polymers 0.000 description 1
239000000919 ceramic Substances 0.000 description 1
239000003795 chemical substances by application Substances 0.000 description 1
239000000460 chlorine Substances 0.000 description 1
229910052801 chlorine Inorganic materials 0.000 description 1
239000011247 coating layer Substances 0.000 description 1
210000001520 comb Anatomy 0.000 description 1
239000002131 composite material Substances 0.000 description 1
239000013078 crystal Substances 0.000 description 1
230000007423 decrease Effects 0.000 description 1
210000004207 dermis Anatomy 0.000 description 1
230000000694 effects Effects 0.000 description 1
230000005518 electrochemistry Effects 0.000 description 1
238000005516 engineering process Methods 0.000 description 1
210000002615 epidermis Anatomy 0.000 description 1
NBVXSUQYWXRMNV-UHFFFAOYSA-N fluoromethane Chemical compound FC NBVXSUQYWXRMNV-UHFFFAOYSA-N 0.000 description 1
239000007849 furan resin Substances 0.000 description 1
239000008103 glucose Substances 0.000 description 1
238000010562 histological examination Methods 0.000 description 1
125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
210000004969 inflammatory cell Anatomy 0.000 description 1
230000002757 inflammatory effect Effects 0.000 description 1
238000001802 infusion Methods 0.000 description 1
210000003734 kidney Anatomy 0.000 description 1
150000002605 large molecules Chemical class 0.000 description 1
229920002521 macromolecule Polymers 0.000 description 1
239000011812 mixed powder Substances 0.000 description 1
230000037311 normal skin Effects 0.000 description 1
239000002504 physiological saline solution Substances 0.000 description 1
229910052697 platinum Inorganic materials 0.000 description 1
229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
229920002239 polyacrylonitrile Polymers 0.000 description 1
229920000728 polyester Polymers 0.000 description 1
239000004926 polymethyl methacrylate Substances 0.000 description 1
229920001155 polypropylene Polymers 0.000 description 1
229920002635 polyurethane Polymers 0.000 description 1
239000004814 polyurethane Substances 0.000 description 1
229910052573 porcelain Inorganic materials 0.000 description 1
239000005373 porous glass Substances 0.000 description 1
230000011514 reflex Effects 0.000 description 1
239000004627 regenerated cellulose Substances 0.000 description 1
238000011160 research Methods 0.000 description 1
229910052710 silicon Inorganic materials 0.000 description 1
239000010703 silicon Substances 0.000 description 1
229920002379 silicone rubber Polymers 0.000 description 1
239000004945 silicone rubber Substances 0.000 description 1
239000007858 starting material Substances 0.000 description 1
238000001356 surgical procedure Methods 0.000 description 1
238000003786 synthesis reaction Methods 0.000 description 1
238000002627 tracheal intubation Methods 0.000 description 1
QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1

Landscapes

Electrotherapy Devices (AREA)
External Artificial Organs (AREA)
Materials For Medical Uses (AREA)
Media Introduction/Drainage Providing Device (AREA)

JP58166502A 1983-03-24 1983-09-12 薬物治療システム用生体端子 Granted JPS6058154A (ja)

Priority Applications (6)

Application Number	Priority Date	Filing Date	Title
JP58166502A JPS6058154A (ja)	1983-09-12	1983-09-12	薬物治療システム用生体端子
CA000450058A CA1247960A (fr)	1983-03-24	1984-03-21	Implant transcutane
DE8484301977T DE3482893D1 (de)	1983-03-24	1984-03-23	Einzelteil zur transkutanen implantation.
EP84301977A EP0120689B1 (fr)	1983-03-24	1984-03-23	Elément pour implantation transcutanée
US07/577,820 US5035711A (en)	1983-03-24	1990-09-05	Transcutaneously implantable element
US07/581,122 US5026397A (en)	1983-03-24	1990-09-10	Transcutaneously implantable element

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP58166502A JPS6058154A (ja)	1983-09-12	1983-09-12	薬物治療システム用生体端子

Publications (2)

Publication Number	Publication Date
JPS6058154A true JPS6058154A (ja)	1985-04-04
JPH0150416B2 JPH0150416B2 (fr)	1989-10-30

Family

ID=15832544

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP58166502A Granted JPS6058154A (ja)	1983-03-24	1983-09-12	薬物治療システム用生体端子

Country Status (1)

Country	Link
JP (1)	JPS6058154A (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS62281954A (ja) *	1986-05-29	1987-12-07	京セラ株式会社	生体内外開通部材
JPH01291870A (ja) *	1988-05-20	1989-11-24	Asahi Optical Co Ltd	経皮素子

1983
- 1983-09-12 JP JP58166502A patent/JPS6058154A/ja active Granted

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS62281954A (ja) *	1986-05-29	1987-12-07	京セラ株式会社	生体内外開通部材
JPH01291870A (ja) *	1988-05-20	1989-11-24	Asahi Optical Co Ltd	経皮素子

Also Published As

Publication number	Publication date
JPH0150416B2 (fr)	1989-10-30

Publication	Publication Date	Title
US5035711A (en)	1991-07-30	Transcutaneously implantable element
US10449270B2 (en)	2019-10-22	Collagen scaffolds, medical implants with same and methods of use
EP0134758A2 (fr)	1985-03-20	Dispositif d'infusion contrôlée d'insuline ou de glucose chez les diabétiques
JPH03505516A (ja)	1991-12-05	グルコース濃度決定のための方法、装置および測定セル組立品
US20200139099A1 (en)	2020-05-07	Apparatus and method for promoting fluid uptake into an implant
US12521047B2 (en)	2026-01-13	Implantable access chamber and associated methods of use
KR20200046795A (ko)	2020-05-07	생체분해성 전지, 이의 제조방법 및 이의 용도
US4445885A (en)	1984-05-01	Insulin releasing supplier
JPS6058154A (ja)	1985-04-04	薬物治療システム用生体端子
JPH02246986A (ja)	1990-10-02	生体内案内具
US20080234563A1 (en)	2008-09-25	Device for and Method of Delivery and Removal of Substances in and From a Tissue or Vessel
JPS6055965A (ja)	1985-04-01	薬物治療システム用生体端子
EP0343114B1 (fr)	1993-10-06	Dispositif transdermique
JPH0313909B2 (fr)	1991-02-25
CA2484012C (fr)	2012-06-26	Materiau support d'ingenierie tissulaire, vaisseau artificiel, element de manchette et revetement destine a des implants
US20250352242A1 (en)	2025-11-20	Insertion system and method for inserting a medical device
JPS61115568A (ja)	1986-06-03	経皮インプラント体
JPH04146763A (ja)	1992-05-20	医療用基材へのゲル状物質付着方法
JPH0213580B2 (fr)	1990-04-04
EP0202917A2 (fr)	1986-11-26	Appareil implantable
JPS60163664A (ja)	1985-08-26	生体適合性複合材
JPH0445190B2 (fr)	1992-07-24
JPS639435A (ja)	1988-01-16	生体用端子
Lyman	1973	Polymers in medicine
JPS62298349A (ja)	1987-12-25	生体用端子

JPS6058154A - 薬物治療システム用生体端子 - Google Patents

Info

Links

Landscapes

Priority Applications (6)

Applications Claiming Priority (1)

Publications (2)

Family

ID=15832544

Family Applications (1)

Country Status (1)

Cited By (2)

Cited By (2)

Also Published As

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