JPS61122222A - コラ−ゲン又はゼラチンとプロタミンとよりなる止血剤 - Google Patents

コラ−ゲン又はゼラチンとプロタミンとよりなる止血剤

Info

Publication number
JPS61122222A
JPS61122222A JP59242472A JP24247284A JPS61122222A JP S61122222 A JPS61122222 A JP S61122222A JP 59242472 A JP59242472 A JP 59242472A JP 24247284 A JP24247284 A JP 24247284A JP S61122222 A JPS61122222 A JP S61122222A
Authority
JP
Japan
Prior art keywords
collagen
protamine
gelatin
hemostatic agent
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP59242472A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0430927B2 (2
Inventor
Yasuharu Noisshiki
泰晴 野一色
Kazuhiko Kodaira
小平　和彦
Masayasu Furuse
古瀬　正康
Teruo Miyata
宮田　暉夫
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koken Co Ltd
Original Assignee
Koken Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koken Co Ltd filed Critical Koken Co Ltd
Priority to JP59242472A priority Critical patent/JPS61122222A/ja
Priority to DE8585114439T priority patent/DE3573214D1/de
Priority to EP85114439A priority patent/EP0183136B1/en
Publication of JPS61122222A publication Critical patent/JPS61122222A/ja
Priority to US07/087,966 priority patent/US4749689A/en
Publication of JPH0430927B2 publication Critical patent/JPH0430927B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/07—Stiffening bandages
    • A61L15/12—Stiffening bandages containing macromolecular materials
    • A61L15/125—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0052—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00—Surgery
    • Y10S128/08—Collagen

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Materials Engineering (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
JP59242472A 1984-11-19 1984-11-19 コラ−ゲン又はゼラチンとプロタミンとよりなる止血剤 Granted JPS61122222A (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP59242472A JPS61122222A (ja) 1984-11-19 1984-11-19 コラ−ゲン又はゼラチンとプロタミンとよりなる止血剤
DE8585114439T DE3573214D1 (en) 1984-11-19 1985-11-13 A hemostatic agent composed of collagen/gelatin and protamine
EP85114439A EP0183136B1 (en) 1984-11-19 1985-11-13 A hemostatic agent composed of collagen/gelatin and protamine
US07/087,966 US4749689A (en) 1984-11-19 1987-08-17 Hemostatic agent composed of collagen/gelatin and protamine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59242472A JPS61122222A (ja) 1984-11-19 1984-11-19 コラ−ゲン又はゼラチンとプロタミンとよりなる止血剤

Publications (2)

Publication Number Publication Date
JPS61122222A true JPS61122222A (ja) 1986-06-10
JPH0430927B2 JPH0430927B2 (2) 1992-05-25

Family

ID=17089590

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59242472A Granted JPS61122222A (ja) 1984-11-19 1984-11-19 コラ−ゲン又はゼラチンとプロタミンとよりなる止血剤

Country Status (4)

Country Link
US (1) US4749689A (2)
EP (1) EP0183136B1 (2)
JP (1) JPS61122222A (2)
DE (1) DE3573214D1 (2)

Families Citing this family (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4713446A (en) * 1985-09-06 1987-12-15 Minnesota Mining And Manufacturing Company Viscoelastic collagen solution for ophthalmic use and method of preparation
US4851513A (en) * 1985-09-06 1989-07-25 Minnesota Mining And Manufacturing Company Viscoelastic collagen solution for opthalmic use and method of preparation
US4883864A (en) * 1985-09-06 1989-11-28 Minnesota Mining And Manufacturing Company Modified collagen compound and method of preparation
ATE83153T1 (de) * 1985-09-10 1992-12-15 Eisai Co Ltd Einen gewebe-plasminogen-aktivator enthaltende zusammensetzung.
DE3608158A1 (de) * 1986-03-12 1987-09-17 Braun Melsungen Ag Mit vernetzter gelatine impraegnierte gefaessprothese und verfahren zu ihrer herstellung
US4954358A (en) * 1986-12-04 1990-09-04 Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo Multiplication inhibitor for Bacillus cereus
USRE34866E (en) * 1987-02-17 1995-02-21 Kensey Nash Corporation Device for sealing percutaneous puncture in a vessel
US4890612A (en) * 1987-02-17 1990-01-02 Kensey Nash Corporation Device for sealing percutaneous puncture in a vessel
DE68915540T2 (de) * 1988-03-09 1994-10-13 Terumo Corp Für zellen eindringbares medizinisches material und kunsthaut.
US5447966A (en) * 1988-07-19 1995-09-05 United States Surgical Corporation Treating bioabsorbable surgical articles by coating with glycerine, polalkyleneoxide block copolymer and gelatin
US6764500B1 (en) * 1989-05-29 2004-07-20 Kensey Nash Corporation Sealing device
US5620461A (en) * 1989-05-29 1997-04-15 Muijs Van De Moer; Wouter M. Sealing device
US5391183A (en) * 1990-09-21 1995-02-21 Datascope Investment Corp Device and method sealing puncture wounds
US7008439B1 (en) * 1990-09-21 2006-03-07 Datascope Investments Corp. Device and method for sealing puncture wounds
US20080077178A1 (en) * 1990-09-21 2008-03-27 Datascope Investment Corp. Device and method for sealing puncture wounds
US5108421A (en) * 1990-10-01 1992-04-28 Quinton Instrument Company Insertion assembly and method of inserting a vessel plug into the body of a patient
US6325789B1 (en) 1990-12-27 2001-12-04 Datascope Investment Corporation Device and method for sealing puncture wounds
US5310407A (en) * 1991-06-17 1994-05-10 Datascope Investment Corp. Laparoscopic hemostat delivery system and method for using said system
US20070135842A1 (en) * 1991-10-22 2007-06-14 Kensey Nash Corporation Sealing device
US5282827A (en) * 1991-11-08 1994-02-01 Kensey Nash Corporation Hemostatic puncture closure system and method of use
US5676689A (en) * 1991-11-08 1997-10-14 Kensey Nash Corporation Hemostatic puncture closure system including vessel location device and method of use
US5403278A (en) * 1992-04-15 1995-04-04 Datascope Investment Corp. Device and method for treating hematomas and false aneurysms
US5413571A (en) * 1992-07-16 1995-05-09 Sherwood Medical Company Device for sealing hemostatic incisions
AU4926193A (en) * 1992-09-21 1994-04-12 Vitaphore Corporation Embolization plugs for blood vessels
US5487392A (en) * 1993-11-15 1996-01-30 Haaga; John R. Biopxy system with hemostatic insert
FR2726571B1 (fr) * 1994-11-03 1997-08-08 Izoret Georges Colle biologique, procede de preparation et dispositif d'application pour colle biologique, et durcisseurs pour colle biologique
US5649959A (en) * 1995-02-10 1997-07-22 Sherwood Medical Company Assembly for sealing a puncture in a vessel
JP3799626B2 (ja) * 1995-04-25 2006-07-19 有限会社ナイセム 心臓血管修復材及びその製造方法
WO1996040033A1 (en) * 1995-06-07 1996-12-19 Clarion Pharmaceuticals Inc. Non-biological patch for hemostasis
AU740072B2 (en) 1996-08-06 2001-10-25 Tyco Group S.A.R.L. Insertion assembly and method of inserting a hemostatic closure device into an incision
US6063061A (en) * 1996-08-27 2000-05-16 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US7871637B2 (en) 1996-08-27 2011-01-18 Baxter International Inc. Dry hemostatic compositions and methods for their preparation
US8603511B2 (en) 1996-08-27 2013-12-10 Baxter International, Inc. Fragmented polymeric compositions and methods for their use
US7435425B2 (en) * 2001-07-17 2008-10-14 Baxter International, Inc. Dry hemostatic compositions and methods for their preparation
US8303981B2 (en) 1996-08-27 2012-11-06 Baxter International Inc. Fragmented polymeric compositions and methods for their use
US6066325A (en) * 1996-08-27 2000-05-23 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US6117444A (en) * 1997-04-10 2000-09-12 Brigham & Women's Hospital Polyethylene glycol/microfibrillar collagen composite serves as a resorbable hemostatic agent
US7914814B2 (en) * 1997-09-17 2011-03-29 Strategic Science & Technologies, Llc Topical delivery of arginine of cause beneficial effects
EP1731175B1 (en) * 1998-11-12 2009-09-30 International Manufacturing Group, Inc. Hemostatic cross-linked dextran beads useful for rapid blood coagulation and hemostatis
US6309454B1 (en) 2000-05-12 2001-10-30 Johnson & Johnson Medical Limited Freeze-dried composite materials and processes for the production thereof
US7923431B2 (en) 2001-12-21 2011-04-12 Ferrosan Medical Devices A/S Haemostatic kit, a method of preparing a haemostatic agent and a method of promoting haemostatis
EP1469865A4 (en) * 2001-12-31 2010-04-14 Crosslink D Inc HEMOSTATIC COMPOSITIONS AND METHODS FOR CONTROLLING HEMORRHAGIA
BR0317237A (pt) * 2002-12-11 2005-11-01 Ferrosan As Dispositivo para amostragem ou coleta, kit, usos de um dispositivo e de um kit, e, métodos para diminuir a quantidade de um marcador em uma área de amostra, para amostrar de modo qualitativo ou quantitativo uma área quanto ao teor de um marcador e para cultivar microorganismos ou células de mamìferos coletados
US20040122349A1 (en) * 2002-12-20 2004-06-24 Lafontaine Daniel M. Closure device with textured surface
US8709038B2 (en) * 2002-12-20 2014-04-29 Boston Scientific Scimed, Inc. Puncture hole sealing device
US8834864B2 (en) * 2003-06-05 2014-09-16 Baxter International Inc. Methods for repairing and regenerating human dura mater
US7942897B2 (en) * 2003-07-10 2011-05-17 Boston Scientific Scimed, Inc. System for closing an opening in a body cavity
US20050033157A1 (en) * 2003-07-25 2005-02-10 Klein Dean A. Multi-modality marking material and method
US7927626B2 (en) * 2003-08-07 2011-04-19 Ethicon, Inc. Process of making flowable hemostatic compositions and devices containing such compositions
ATE475434T1 (de) * 2004-01-30 2010-08-15 Ferrosan As Hämostatische sprays und zusammensetzungen
RU2369408C2 (ru) * 2004-07-09 2009-10-10 Ферросан А/С Гемостатическая композиция, включающая гиалуроновую кислоту
US20070248653A1 (en) * 2006-04-20 2007-10-25 Cochrum Kent C Hemostatic compositions and methods for controlling bleeding
BRPI0712088B8 (pt) * 2006-05-31 2021-06-22 Baxter Healthcare Sa uso de uma biomatriz de lâmina de colágeno de múltiplas camadas microscópicas não porosa e hermética a fluido
TWI436793B (zh) 2006-08-02 2014-05-11 巴克斯特國際公司 快速作用之乾密封膠及其使用和製造方法
AR069109A1 (es) 2007-10-30 2009-12-30 Baxter Int Uso de una biomatriz de colageno biofuncional regenerativa para tratar defectos viscerales o parietales
WO2009109194A2 (en) 2008-02-29 2009-09-11 Ferrosan A/S Device for promotion of hemostasis and/or wound healing
US20100256671A1 (en) * 2009-04-07 2010-10-07 Biomedica Management Corporation Tissue sealant for use in noncompressible hemorrhage
US9039783B2 (en) * 2009-05-18 2015-05-26 Baxter International, Inc. Method for the improvement of mesh implant biocompatibility
DK2442835T3 (en) 2009-06-16 2015-03-16 Baxter Int Styptic sponge
BR112012014773A2 (pt) 2009-12-16 2015-11-03 Baxter Healthcare Sa esponja de compósito hemostática, método para fabricar uma esponja de compósito hemostática, e, uso da referida esponja
SA111320355B1 (ar) 2010-04-07 2015-01-08 Baxter Heathcare S A إسفنجة لايقاف النزف
AU2011260258B2 (en) 2010-06-01 2015-07-09 Baxter Healthcare S.A. Process for making dry and stable hemostatic compositions
MX352875B (es) 2010-06-01 2017-12-13 Baxter Healthcare Sa Proceso para elaborar composiciones hemostaticas secas y estables.
CA2801118C (en) 2010-06-01 2016-01-05 Baxter International Inc. Process for making dry and stable hemostatic compositions
CA2851321C (en) 2011-10-11 2020-07-07 Baxter International Inc. Hemostatic compositions
HK1201212A1 (en) 2011-10-11 2015-08-28 Baxter International Inc Hemostatic compositions
ES2553702T3 (es) 2011-10-27 2015-12-11 Baxter International Inc Composiciones hemostáticas
JP6241624B2 (ja) 2012-03-06 2017-12-06 フェロサン メディカル デバイシーズ エイ／エス 止血ペーストを収容する加圧容器
CN104349797B (zh) 2012-06-12 2017-10-27 弗罗桑医疗设备公司 干止血组合物
EP3010419B1 (en) 2013-06-21 2020-05-20 Ferrosan Medical Devices A/S Vacuum expanded dry composition and syringe for retaining same
EP3079731B1 (en) 2013-12-11 2018-08-08 Ferrosan Medical Devices A/S Dry composition comprising an extrusion enhancer
JP6726852B2 (ja) 2014-10-13 2020-07-22 フェッローサン メディカル ディバイス エー／エス 止血および創傷治癒に使用するための乾燥組成物
RU2705905C2 (ru) 2014-12-24 2019-11-12 Ферросан Медикал Дивайсиз А/С Шприц для удерживания и смешивания первого и второго веществ
AU2016290433B2 (en) 2015-07-03 2018-05-24 Ferrosan Medical Devices A/S Syringe for mixing two components and for retaining a vacuum in a storage condition
JP6862441B2 (ja) 2015-11-08 2021-04-21 オムリックス・バイオファーマシューティカルズ・リミテッドＯｍｒｉｘ Ｂｉｏｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ． セルロース系短尺繊維及び長尺繊維の止血混合物
CN112368028A (zh) 2018-05-09 2021-02-12 弗罗桑医疗设备公司 用于制备止血组合物的方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2584093A (en) * 1949-07-07 1952-01-29 Sharp & Dohme Inc Method of purifying diphtheria toxoids
US3717469A (en) * 1970-01-12 1973-02-20 I Elementoorganischeskikt Soed Granular protein containing food product resembling the natural caviar of sturgeon, salmon and other fish, and a method of preparing same
US3742955A (en) * 1970-09-29 1973-07-03 Fmc Corp Fibrous collagen derived product having hemostatic and wound binding properties
CA1073360A (en) * 1975-10-22 1980-03-11 John R. Daniels Non-antigenic collagen and articles of manufacture
GB1584080A (en) * 1977-12-05 1981-02-04 Ethicon Inc Absorbable hemostatic composition
US4238480A (en) * 1978-05-19 1980-12-09 Sawyer Philip Nicholas Method for preparing an improved hemostatic agent and method of employing the same
US4215200A (en) * 1978-10-02 1980-07-29 Cornell Research Foundation, Inc. Chemically and enzymatically modified collagen hemostatic agent
US4223984A (en) * 1979-04-04 1980-09-23 Opticol Corporation Collagen soft contact lens
US4268131A (en) * 1979-04-11 1981-05-19 Opticol Corporation Fiber collagen contact lens
US4374830A (en) * 1979-10-04 1983-02-22 Research Corp. Platelet aggregating material from equine arterial tissue
US4260228A (en) * 1980-01-21 1981-04-07 Opticol Corporation Collagen gel contact lens and method of preparation
US4271070A (en) * 1980-05-05 1981-06-02 Cornell Research Foundation, Inc. Chemically-modified fiber collagen hemostatic agents
US4424208A (en) * 1982-01-11 1984-01-03 Collagen Corporation Collagen implant material and method for augmenting soft tissue
US4582640A (en) * 1982-03-08 1986-04-15 Collagen Corporation Injectable cross-linked collagen implant material
JPS58180162A (ja) * 1982-04-19 1983-10-21 株式会社高研 抗血栓性医用材料
JPS59164723A (ja) * 1983-03-10 1984-09-17 Koken:Kk 再生コラーゲンフイブリルを含有する基質及びその製造方法
JPS6028936A (ja) * 1983-07-27 1985-02-14 Koken:Kk アテロコラ−ゲン水溶液およびその製造方法
US4557764A (en) * 1984-09-05 1985-12-10 Collagen Corporation Process for preparing malleable collagen and the product thereof

Also Published As

Publication number Publication date
US4749689A (en) 1988-06-07
JPH0430927B2 (2) 1992-05-25
EP0183136B1 (en) 1989-09-27
EP0183136A1 (en) 1986-06-04
DE3573214D1 (en) 1989-11-02

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