JPS6155894B2 - - Google Patents

Info

Publication number: JPS6155894B2
Authority: JP; Japan
Prior art keywords: albumin; hma; mercaptalbumin; preparation; plasma
Prior art date: 1983-09-09
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

JP58165128A

Other languages

English (en)

Japanese (ja)

Other versions

JPS6056925A (ja

Inventor

Masaru Sogami

Koji Noguchi

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Asahi Kasei Corp

Asahi Kasei Medical Co Ltd

Original Assignee

Asahi Medical Co Ltd

Asahi Kasei Kogyo KK

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-09-09

Filing date

1983-09-09

Publication date

1986-11-29

1983-09-09 Application filed by Asahi Medical Co Ltd, Asahi Kasei Kogyo KK filed Critical Asahi Medical Co Ltd

1983-09-09 Priority to JP58165128A priority Critical patent/JPS6056925A/ja

1985-04-02 Publication of JPS6056925A publication Critical patent/JPS6056925A/ja

1986-11-29 Publication of JPS6155894B2 publication Critical patent/JPS6155894B2/ja

Status Granted legal-status Critical Current

Links

108010088751 Albumins Proteins 0.000 claims description 42
102000009027 Albumins Human genes 0.000 claims description 42
238000002360 preparation method Methods 0.000 claims description 24
108010004546 mercaptoalbumin Proteins 0.000 claims description 21
108010053070 Glutathione Disulfide Proteins 0.000 description 13
YPZRWBKMTBYPTK-BJDJZHNGSA-N glutathione disulfide Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@H](C(=O)NCC(O)=O)CSSC[C@@H](C(=O)NCC(O)=O)NC(=O)CC[C@H](N)C(O)=O YPZRWBKMTBYPTK-BJDJZHNGSA-N 0.000 description 13
YPZRWBKMTBYPTK-UHFFFAOYSA-N oxidized gamma-L-glutamyl-L-cysteinylglycine Natural products OC(=O)C(N)CCC(=O)NC(C(=O)NCC(O)=O)CSSCC(C(=O)NCC(O)=O)NC(=O)CCC(N)C(O)=O YPZRWBKMTBYPTK-UHFFFAOYSA-N 0.000 description 13
LEVWYRKDKASIDU-QWWZWVQMSA-N D-cystine Chemical compound OC(=O)[C@H](N)CSSC[C@@H](N)C(O)=O LEVWYRKDKASIDU-QWWZWVQMSA-N 0.000 description 12
229960003067 cystine Drugs 0.000 description 12
210000004369 blood Anatomy 0.000 description 8
239000008280 blood Substances 0.000 description 8
238000002474 experimental method Methods 0.000 description 8
108010059904 nonmercaptalbumin Proteins 0.000 description 8
239000000203 mixture Substances 0.000 description 7
239000000047 product Substances 0.000 description 7
238000000034 method Methods 0.000 description 6
210000002966 serum Anatomy 0.000 description 6
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
235000001014 amino acid Nutrition 0.000 description 4
150000001413 amino acids Chemical class 0.000 description 4
238000005194 fractionation Methods 0.000 description 4
238000004811 liquid chromatography Methods 0.000 description 4
208000019423 liver disease Diseases 0.000 description 4
238000004458 analytical method Methods 0.000 description 3
239000010836 blood and blood product Substances 0.000 description 3
229940125691 blood product Drugs 0.000 description 3
XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 description 3
235000018417 cysteine Nutrition 0.000 description 3
238000000502 dialysis Methods 0.000 description 3
201000010099 disease Diseases 0.000 description 3
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
238000009472 formulation Methods 0.000 description 3
238000010438 heat treatment Methods 0.000 description 3
210000003734 kidney Anatomy 0.000 description 3
238000011160 research Methods 0.000 description 3
VZZUJVDCIBINIT-YDALLXLXSA-N (2s)-2-acetamido-3-(1h-indol-3-yl)propanoic acid;sodium Chemical compound [Na].C1=CC=C2C(C[C@H](NC(=O)C)C(O)=O)=CNC2=C1 VZZUJVDCIBINIT-YDALLXLXSA-N 0.000 description 2
108010017384 Blood Proteins Proteins 0.000 description 2
102000004506 Blood Proteins Human genes 0.000 description 2
108091006905 Human Serum Albumin Proteins 0.000 description 2
102000008100 Human Serum Albumin Human genes 0.000 description 2
239000000306 component Substances 0.000 description 2
150000001875 compounds Chemical class 0.000 description 2
238000004128 high performance liquid chromatography Methods 0.000 description 2
208000017169 kidney disease Diseases 0.000 description 2
238000004519 manufacturing process Methods 0.000 description 2
239000000463 material Substances 0.000 description 2
239000012528 membrane Substances 0.000 description 2
238000012856 packing Methods 0.000 description 2
238000000746 purification Methods 0.000 description 2
229960005480 sodium caprylate Drugs 0.000 description 2
239000011780 sodium chloride Substances 0.000 description 2
BYKRNSHANADUFY-UHFFFAOYSA-M sodium octanoate Chemical compound [Na+].CCCCCCCC([O-])=O BYKRNSHANADUFY-UHFFFAOYSA-M 0.000 description 2
229910000162 sodium phosphate Inorganic materials 0.000 description 2
239000001488 sodium phosphate Substances 0.000 description 2
238000012360 testing method Methods 0.000 description 2
RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 2
229920000298 Cellophane Polymers 0.000 description 1
XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 description 1
108010071390 Serum Albumin Proteins 0.000 description 1
102000007562 Serum Albumin Human genes 0.000 description 1
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
238000010521 absorption reaction Methods 0.000 description 1
239000012503 blood component Substances 0.000 description 1
238000006243 chemical reaction Methods 0.000 description 1
230000007423 decrease Effects 0.000 description 1
VHJLVAABSRFDPM-QWWZWVQMSA-N dithiothreitol Chemical compound SC[C@@H](O)[C@H](O)CS VHJLVAABSRFDPM-QWWZWVQMSA-N 0.000 description 1
239000012467 final product Substances 0.000 description 1
239000012530 fluid Substances 0.000 description 1
238000005338 heat storage Methods 0.000 description 1
239000013067 intermediate product Substances 0.000 description 1
239000007788 liquid Substances 0.000 description 1
238000005259 measurement Methods 0.000 description 1
238000000691 measurement method Methods 0.000 description 1
239000000825 pharmaceutical preparation Substances 0.000 description 1
229940127557 pharmaceutical product Drugs 0.000 description 1
150000003384 small molecules Chemical class 0.000 description 1
239000011593 sulfur Substances 0.000 description 1
229910052717 sulfur Inorganic materials 0.000 description 1

Landscapes

Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

JP58165128A 1983-09-09 1983-09-09 アルブミン製剤 Granted JPS6056925A (ja)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
JP58165128A JPS6056925A (ja)	1983-09-09	1983-09-09	アルブミン製剤

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP58165128A JPS6056925A (ja)	1983-09-09	1983-09-09	アルブミン製剤

Publications (2)

Publication Number	Publication Date
JPS6056925A JPS6056925A (ja)	1985-04-02
JPS6155894B2 true JPS6155894B2 (da)	1986-11-29

Family

ID=15806436

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP58165128A Granted JPS6056925A (ja)	1983-09-09	1983-09-09	アルブミン製剤

Country Status (1)

Country	Link
JP (1)	JPS6056925A (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP5476538B2 (ja) *	2008-03-31	2014-04-23	学校法人久留米大学	肝疾患に伴う浮腫の判定方法

1983
- 1983-09-09 JP JP58165128A patent/JPS6056925A/ja active Granted

Also Published As

Publication number	Publication date
JPS6056925A (ja)	1985-04-02

Similar Documents

Publication	Publication Date	Title
Suliman et al.	1997	Total, free, and protein-bound sulphur amino acids in uraemic patients.
CA1142175A (en)	1983-03-01	Fractionation of protein mixtures by salting out followed by dialysis treatment
FR2501692A1 (fr)	1982-09-17	Nouveau produit d'erythropoietine et procede pour sa preparation
JPS6232A (ja)	1987-01-06	慢性関節リウマチ性貧血治療剤
Grodzicki et al.	2009	Results of treatment of acute liver failure patients with use of the prometheus FPSA system
Wiśniewska-Knypl et al.	1972	Binding of cadmium on metallothionein in man: an analysis of a fatal poisoning by cadmium iodide
JPS5822085B2 (ja)	1983-05-06	静注用ガンマ・グロブリン製剤
JPH05255096A (ja)	1993-10-05	初老期痴呆または老年痴呆の治療用医薬組成物
Saari et al.	1976	Retinol-binding protein in bovine retina: isolation and partial characterization
FR2701263B1 (fr)	1995-04-21	Procédé d'obtention d'une composition aqueuse protéinique, composition correspondante, glycoprotéine contenue et son utilisation pour la stabilisation de l'albumine et la détection ou le dosage d'anticorps.
Wibell et al.	1976	Urinary Excretion of β2 Microglobulin after the Induction of a Diuresis: A Study in Healthy Subjects
JPH0684965B2 (ja)	1994-10-26	血液製剤中の不適合反応原因物質の試験法
JPH04346934A (ja)	1992-12-02	γ−グロブリンの液状製剤
Harden et al.	1978	Aplastic anemia following exposure to paradichlorobenzene and naphthalene
JPS6056925A (ja)	1985-04-02	アルブミン製剤
FI78483B (fi)	1989-04-28	Rening av modulatorer foer immunsystem.
JPH02288899A (ja)	1990-11-28	成熟肝実質細胞増殖因子（ｉ）
WO2004089404A1 (fr)	2004-10-21	Conjugat d'hemoglobine, son procede de preparation et son utilisation
JPS6254776B2 (da)	1987-11-17
JPS61194026A (ja)	1986-08-28	アルブミン製剤の製造方法
JPS61194027A (ja)	1986-08-28	アルブミン製剤の製造法
JPS62153224A (ja)	1987-07-08	プラスミノゲン製剤
JP4703922B2 (ja)	2011-06-15	蛋白質の精製法
JPS5823631A (ja)	1983-02-12	安定な固体の人血漿コリンエステラ−ゼ製剤の製法
Webster et al.	1969	Acute post-streptococcal toxaemic renal failure