JPS62500073A - エシェリキア・コリｌｔ−ｂエンテロトキシンサブユニットの製造 - Google Patents

エシェリキア・コリｌｔ−ｂエンテロトキシンサブユニットの製造

Info

Publication number
JPS62500073A
JPS62500073A JP60503149A JP50314985A JPS62500073A JP S62500073 A JPS62500073 A JP S62500073A JP 60503149 A JP60503149 A JP 60503149A JP 50314985 A JP50314985 A JP 50314985A JP S62500073 A JPS62500073 A JP S62500073A
Authority
JP
Japan
Prior art keywords
enterotoxin
cholera
administering
human
effective amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP60503149A
Other languages
English (en)
Japanese (ja)
Inventor
クレメンツ，ジヨン　デイー
Original Assignee
プラクシス　バイオロジツクス，インコ−ポレ−テツド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by プラクシス　バイオロジツクス，インコ−ポレ−テツド filed Critical プラクシス　バイオロジツクス，インコ−ポレ−テツド
Publication of JPS62500073A publication Critical patent/JPS62500073A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Gram-negative bacteria
    • C07K16/1228—Enterobacterales (O), e.g. Citrobacter (G), Serratia (G), Proteus (G), Providencia (G), Morganella (G) or Yersinia (G)
    • C07K16/1232—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/28—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Vibrionaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Gram-negative bacteria
    • C07K16/1239—Gram-negative bacteria from Vibrionaceae (G)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56916—Enterobacteria, e.g. shigella, salmonella, klebsiella, serratia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
JP60503149A 1984-07-09 1985-07-03 エシェリキア・コリｌｔ−ｂエンテロトキシンサブユニットの製造 Pending JPS62500073A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62887384A 1984-07-09 1984-07-09
US628873 1984-07-09

Publications (1)

Publication Number Publication Date
JPS62500073A true JPS62500073A (ja) 1987-01-16

Family

ID=24520666

Family Applications (1)

Application Number Title Priority Date Filing Date
JP60503149A Pending JPS62500073A (ja) 1984-07-09 1985-07-03 エシェリキア・コリｌｔ−ｂエンテロトキシンサブユニットの製造

Country Status (10)

Country Link
EP (1) EP0168322B1 (de)
JP (1) JPS62500073A (de)
AT (1) ATE62270T1 (de)
AU (1) AU598725B2 (de)
CA (1) CA1340372C (de)
DE (1) DE3582373D1 (de)
DK (1) DK311485A (de)
ES (1) ES8703526A1 (de)
IE (1) IE59393B1 (de)
WO (1) WO1986000647A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02243633A (ja) * 1988-04-08 1990-09-27 Kitasato Inst:The ワクチン製剤

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5137721A (en) * 1981-03-09 1992-08-11 Cetus Corporation Employing strains of E. coli expressing non-indigenous adhesins and toxoids of E. coli
US4748018A (en) * 1984-02-07 1988-05-31 Stolle Research & Development Corp. Method of passive immunization of mammals using avian antibody
US4808700A (en) * 1984-07-09 1989-02-28 Praxis Biologics, Inc. Immunogenic conjugates of non-toxic E. coli LT-B enterotoxin subunit and capsular polymers
AR241713A1 (es) * 1984-08-30 1992-11-30 Smithkline Beckman Corp Molecula de dna con una secuencia de bases que codifica la proteina c13 y preparacion de vacunas contra la gripe.
CA1339465C (en) * 1986-04-30 1997-09-16 Richard J. Massey Electrochemiluminescent assays
WO1990002484A1 (en) * 1988-09-06 1990-03-22 Washington University Oral immunization by transgenic plants
US6043057A (en) * 1988-09-16 2000-03-28 Vitec Aktiebolag Recombinant systems for expression of the cholera B-sub-unit with the aid of foreign promoters and/or leader peptides
DE3843894A1 (de) * 1988-12-24 1990-06-28 Behringwerke Ag Plasmide mit translations-start-stop-start codon-konfiguration zur expression von proteinen in e.coli
JPH03187383A (ja) * 1989-09-04 1991-08-15 Takeda Chem Ind Ltd 発現プラスミドおよびその用途
EP2076531B1 (de) 2006-10-12 2011-11-23 Istituto di Ricerche di Biologia Molecolare P. Angeletti S.R.L. Fusionsprotein aus telomerase und reverser transkriptase, dafür codierende nukleotide und anwendungen davon
US9815886B2 (en) 2014-10-28 2017-11-14 Adma Biologics, Inc. Compositions and methods for the treatment of immunodeficiency
US10259865B2 (en) 2017-03-15 2019-04-16 Adma Biologics, Inc. Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57171926A (en) * 1981-03-09 1982-10-22 Cetus Corp Vaccine

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4328209A (en) * 1979-04-11 1982-05-04 Board Of Regents, The University Of Texas System Cholera vaccine
US4361550A (en) * 1979-12-04 1982-11-30 Ortho Pharmaceutical Corporation Complement-fixing monoclonal antibody to human suppressor T cells and methods of preparing same
NL8000527A (nl) * 1980-01-29 1981-08-17 Stichting Vrienden Van De Stic Werkwijze voor het bevorderen van hybridisatie van cellen in vitro en van de produktie en uitscheiding van stoffen, gevormd door dergelijke celhybriden, werkwijze voor het bevorderen van de produktie van monoclonale antilichamen in vitro door toepassing van een hybridomatechniek, alsmede endotheelcellen en/of supernatant van endotheelcellen.
US4427653A (en) * 1981-01-26 1984-01-24 President And Fellows Of Harvard College Method of making monoclonal antibodies
US4411888A (en) * 1981-06-22 1983-10-25 The University Of Rochester Composition of a novel immunogen for protection against diarrheal disease caused by enterotoxigenic Escherichia coli
WO1983002456A2 (fr) * 1982-01-18 1983-07-21 Ceska, Miroslav Nouveaux plasmides et souches de bacteries et leur procede de fabrication
JPS58146596A (ja) * 1982-02-25 1983-09-01 Takeda Chem Ind Ltd 組換えｄｎａ、それで形質転換させた微生物およびそれらの用途
US4666837A (en) * 1982-05-24 1987-05-19 Smithkline-Rit DNA sequences, recombinant DNA molecules and processes for producing the A and B subunits of cholera toxin and preparations containing so-obtained subunit or subunits
US4882278A (en) * 1983-04-29 1989-11-21 President And Fellows Of Harvard College Non-toxinogenic vibrio cholerae mutants
US4637980A (en) * 1983-08-09 1987-01-20 Smithkline Beckman Corporation Externalization of products of bacteria
GB8333131D0 (en) * 1983-12-12 1984-01-18 Glaxo Group Ltd Microbiological process
US4808700A (en) * 1984-07-09 1989-02-28 Praxis Biologics, Inc. Immunogenic conjugates of non-toxic E. coli LT-B enterotoxin subunit and capsular polymers

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57171926A (en) * 1981-03-09 1982-10-22 Cetus Corp Vaccine

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02243633A (ja) * 1988-04-08 1990-09-27 Kitasato Inst:The ワクチン製剤

Also Published As

Publication number Publication date
ATE62270T1 (de) 1991-04-15
DK311485D0 (da) 1985-07-08
EP0168322B1 (de) 1991-04-03
ES544967A0 (es) 1987-02-16
IE851710L (en) 1986-01-09
CA1340372C (en) 1999-02-02
AU598725B2 (en) 1990-07-05
IE59393B1 (en) 1994-02-23
DK311485A (da) 1986-01-10
AU4458785A (en) 1986-01-16
EP0168322A2 (de) 1986-01-15
EP0168322A3 (en) 1986-11-20
ES8703526A1 (es) 1987-02-16
WO1986000647A1 (en) 1986-01-30
DE3582373D1 (de) 1991-05-08

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