JPS63227582A - 新規2−(2,3−ジヒドロ−2−オキソ−3−ベンゾフラニル)酢酸誘導体その製造法およびそれを含有する薬学的組成物 - Google Patents
新規2−(2,3−ジヒドロ−2−オキソ−3−ベンゾフラニル)酢酸誘導体その製造法およびそれを含有する薬学的組成物Info
- Publication number
- JPS63227582A JPS63227582A JP63044081A JP4408188A JPS63227582A JP S63227582 A JPS63227582 A JP S63227582A JP 63044081 A JP63044081 A JP 63044081A JP 4408188 A JP4408188 A JP 4408188A JP S63227582 A JPS63227582 A JP S63227582A
- Authority
- JP
- Japan
- Prior art keywords
- carbon atoms
- radical
- formula
- general formula
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8702630 | 1987-02-27 | ||
| FR8702630A FR2611713B1 (fr) | 1987-02-27 | 1987-02-27 | Nouveaux derives de l'acide (dihydro-2,3 oxo-2 benzofurannyl-3)-2 acetique, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS63227582A true JPS63227582A (ja) | 1988-09-21 |
| JPH0558633B2 JPH0558633B2 (2) | 1993-08-27 |
Family
ID=9348401
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP63044081A Granted JPS63227582A (ja) | 1987-02-27 | 1988-02-26 | 新規2−(2,3−ジヒドロ−2−オキソ−3−ベンゾフラニル)酢酸誘導体その製造法およびそれを含有する薬学的組成物 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US4859700A (2) |
| EP (1) | EP0282390B1 (2) |
| JP (1) | JPS63227582A (2) |
| AT (1) | ATE63309T1 (2) |
| AU (1) | AU598345B2 (2) |
| CA (1) | CA1313871C (2) |
| DE (1) | DE3862660D1 (2) |
| DK (1) | DK167063B1 (2) |
| ES (1) | ES2009553A6 (2) |
| FR (1) | FR2611713B1 (2) |
| GR (1) | GR1000125B (2) |
| IE (1) | IE60500B1 (2) |
| NZ (1) | NZ223663A (2) |
| OA (1) | OA08813A (2) |
| PT (1) | PT86851B (2) |
| ZA (1) | ZA881383B (2) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2061953T3 (es) * | 1988-11-24 | 1994-12-16 | Akzo Nv | Un procedimiento para preparar una composicion farmaceutica. |
| GB9024960D0 (en) * | 1990-11-16 | 1991-01-02 | Ici Plc | Chemical process |
| GB9205049D0 (en) * | 1992-03-09 | 1992-04-22 | Ici Plc | Polycyclic dyes |
| US6207665B1 (en) * | 1997-06-12 | 2001-03-27 | Schering Aktiengesellschaft | Piperazine derivatives and their use as anti-inflammatory agents |
| CA2415815A1 (en) * | 2000-07-06 | 2002-01-17 | Nigel H. Greig | Tetrahydrobenzothiazole analogues as neuroprotective agents |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2513698A (en) * | 1945-03-09 | 1950-07-04 | Abbott Lab | 2 (3) benxofuranone derivatives and methods of making them |
| GB1173312A (en) * | 1966-03-17 | 1969-12-10 | Kefalas As | Heterocyclic Compounds |
| GB2044272B (en) * | 1979-02-05 | 1983-03-16 | Sandoz Ltd | Stabilising polymers |
| US4514415A (en) * | 1981-10-28 | 1985-04-30 | Ciba Geigy Corporation | Benzofuran-2(3H)-ones used as anti-inflammatory agents |
| US4663347A (en) * | 1983-10-31 | 1987-05-05 | Merck Frosst Canada, Inc. | Benzofuran 2-carboxylic acid esters useful as inhibitors of leukotriene biosynthesis |
| GB8426424D0 (en) * | 1984-10-19 | 1984-11-28 | Biorex Laboratories Ltd | Chalcone derivatives |
| FR2593504B1 (fr) * | 1986-01-30 | 1988-12-09 | Ile De France | Nouveaux derives de dihydrobenzofuranne - et de chromane - carboxamides, leurs procedes de preparation et leur utilisation comme neuroleptiques |
-
1987
- 1987-02-27 FR FR8702630A patent/FR2611713B1/fr not_active Expired - Lifetime
-
1988
- 1988-02-01 CA CA000557812A patent/CA1313871C/fr not_active Expired - Fee Related
- 1988-02-12 US US07/155,352 patent/US4859700A/en not_active Expired - Fee Related
- 1988-02-26 AU AU12344/88A patent/AU598345B2/en not_active Ceased
- 1988-02-26 OA OA59290A patent/OA08813A/xx unknown
- 1988-02-26 EP EP19880400441 patent/EP0282390B1/fr not_active Expired - Lifetime
- 1988-02-26 AT AT88400441T patent/ATE63309T1/de not_active IP Right Cessation
- 1988-02-26 DK DK104388A patent/DK167063B1/da not_active IP Right Cessation
- 1988-02-26 NZ NZ223663A patent/NZ223663A/en unknown
- 1988-02-26 IE IE52888A patent/IE60500B1/en not_active IP Right Cessation
- 1988-02-26 GR GR880100111A patent/GR1000125B/el unknown
- 1988-02-26 DE DE8888400441T patent/DE3862660D1/de not_active Expired - Lifetime
- 1988-02-26 ZA ZA881383A patent/ZA881383B/xx unknown
- 1988-02-26 PT PT86851A patent/PT86851B/pt not_active IP Right Cessation
- 1988-02-26 JP JP63044081A patent/JPS63227582A/ja active Granted
- 1988-02-27 ES ES8800577A patent/ES2009553A6/es not_active Expired
-
1989
- 1989-01-17 US US07/298,107 patent/US4885299A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ZA881383B (en) | 1988-12-28 |
| DK167063B1 (da) | 1993-08-23 |
| GR1000125B (el) | 1991-07-31 |
| PT86851A (pt) | 1988-03-01 |
| EP0282390B1 (fr) | 1991-05-08 |
| JPH0558633B2 (2) | 1993-08-27 |
| DK104388A (da) | 1988-08-28 |
| ES2009553A6 (es) | 1989-10-01 |
| AU1234488A (en) | 1988-09-01 |
| US4885299A (en) | 1989-12-05 |
| IE60500B1 (en) | 1994-07-27 |
| OA08813A (fr) | 1989-03-31 |
| PT86851B (pt) | 1992-05-29 |
| DE3862660D1 (de) | 1991-06-13 |
| ATE63309T1 (de) | 1991-05-15 |
| NZ223663A (en) | 1990-01-29 |
| US4859700A (en) | 1989-08-22 |
| IE880528L (en) | 1988-08-27 |
| GR880100111A (en) | 1988-12-16 |
| EP0282390A1 (fr) | 1988-09-14 |
| AU598345B2 (en) | 1990-06-21 |
| FR2611713A1 (fr) | 1988-09-09 |
| CA1313871C (fr) | 1993-02-23 |
| DK104388D0 (da) | 1988-02-26 |
| FR2611713B1 (fr) | 1990-11-30 |
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