JPS6498A - Production of 2',3'-deoxynucleoside - Google Patents

Production of 2',3'-deoxynucleoside

Info

Publication number
JPS6498A
JPS6498A JP63067978A JP6797888A JPS6498A JP S6498 A JPS6498 A JP S6498A JP 63067978 A JP63067978 A JP 63067978A JP 6797888 A JP6797888 A JP 6797888A JP S6498 A JPS6498 A JP S6498A
Authority
JP
Japan
Prior art keywords
expressed
protecting group
react
allowed
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP63067978A
Other languages
English (en)
Other versions
JPH0198A (ja
Inventor
Vittorio Farina
John C Martin
Daniel A Benigni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of JPH0198A publication Critical patent/JPH0198A/ja
Publication of JPS6498A publication Critical patent/JPS6498A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP63067978A 1987-03-20 1988-03-22 Production of 2',3'-deoxynucleoside Pending JPS6498A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2881787A 1987-03-20 1987-03-20
US28817 1987-03-20

Publications (2)

Publication Number Publication Date
JPH0198A JPH0198A (ja) 1989-01-05
JPS6498A true JPS6498A (en) 1989-01-05

Family

ID=21845603

Family Applications (1)

Application Number Title Priority Date Filing Date
JP63067978A Pending JPS6498A (en) 1987-03-20 1988-03-22 Production of 2',3'-deoxynucleoside

Country Status (3)

Country Link
EP (1) EP0285884A3 (ja)
JP (1) JPS6498A (ja)
IL (1) IL85778A0 (ja)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09505306A (ja) * 1993-11-16 1997-05-27 ジンタ・インコーポレイテッド 非ホスホネートヌクレオシド間結合と混合している不確定キラリティーのホスホネートヌクレオシド間結合を有する合成オリゴマー
CN104950133A (zh) * 2015-07-06 2015-09-30 浙江大学 微流体流速传感芯片、检测系统及检测方法
CN104977079A (zh) * 2015-06-29 2015-10-14 北京航天易联科技发展有限公司 一种信号解调方法和装置
US9653313B2 (en) 2013-05-01 2017-05-16 Sensor Electronic Technology, Inc. Stress relieving semiconductor layer
US9771634B2 (en) 2014-11-05 2017-09-26 Companhia Brasileira De Metalurgia E Mineração Processes for producing low nitrogen essentially nitride-free chromium and chromium plus niobium-containing nickel-based alloys and the resulting chromium and nickel-based alloys
NO20160930A1 (en) * 2016-05-31 2017-12-01 Inst Energiteknik Method, powder, film, electrode & battery
US9854811B2 (en) * 2006-11-16 2018-01-02 Coats Agri Aloe, Llc Treatment of plants, fruits and vegetables to increase growth, eliminate insects and increase shelf-life with aloe vera gel

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT395977B (de) * 1987-07-17 1993-04-26 Bristol Myers Squibb Co Verfahren zur herstellung von didesoxyinosin durch entaminierung von didesoxyadenosin
SE8802687D0 (sv) * 1988-07-20 1988-07-20 Astra Ab Nucleoside derivatives
JP2619710B2 (ja) * 1989-02-27 1997-06-11 日本製紙 株式会社 ２′，３′−ジデオキシプリンヌクレオシド類の製造方法
US5059690A (en) * 1990-03-01 1991-10-22 E. R. Squibb & Sons, Inc. Purinyl tetrahydrofurans
US5164520A (en) * 1989-04-24 1992-11-17 E. R. Squibb & Sons, Inc. Intermediates for purinyl and pyrimidinyl tetrahydrofurans
NZ232993A (en) * 1989-04-24 1992-10-28 Squibb & Sons Inc Purinyl and pyrimidinyl tetrahydrofurans
US5145960A (en) * 1989-04-24 1992-09-08 E. R. Squibb & Sons, Inc. Pyrimidinyl tetrahydrofurans
EP0411467A3 (en) * 1989-08-01 1992-03-04 Lonza Ag Process for the preparation of pure adenin
JPH0637391B2 (ja) * 1989-09-29 1994-05-18 日本製紙株式会社 抗エイズウイルス剤
US6069252A (en) 1990-02-01 2000-05-30 Emory University Method of resolution and antiviral activity of 1,3-oxathiolane nucleoside enantiomers
GB9226927D0 (en) * 1992-12-24 1993-02-17 Iaf Biochem Int Dideoxy nucleoside analogues
TW374087B (en) * 1993-05-25 1999-11-11 Univ Yale L-2',3'-dideoxy nucleotide analogs as anti-hepatitis B(HBV) and anti-HIV agents
US5627160A (en) * 1993-05-25 1997-05-06 Yale University L-2',3'-dideoxy nucleoside analogs as anti-hepatitis B (HBV) and anti-HIV agents
US20020120130A1 (en) 1993-09-10 2002-08-29 Gilles Gosselin 2' or 3' -deoxy and 2', 3' -dideoxy-beta-L-pentofuranonucleo-side compounds, method of preparation and application in therapy, especially as anti- viral agents
FR2709754B1 (fr) * 1993-09-10 1995-12-01 Centre Nat Rech Scient Composés 2' ou 3'-déoxy- et 2', 3'-didéoxy-beta-L-pentofuranonucléosides, procédé de préparation et application thérapeutique, notamment anti-virale.
US5587362A (en) * 1994-01-28 1996-12-24 Univ. Of Ga Research Foundation L-nucleosides
WO1996012728A1 (en) * 1994-10-24 1996-05-02 Genencor International, Inc. L-pyranosyl nucleosides
US5559101A (en) * 1994-10-24 1996-09-24 Genencor International, Inc. L-ribofuranosyl nucleosides
US6391859B1 (en) 1995-01-27 2002-05-21 Emory University [5-Carboxamido or 5-fluoro]-[2′,3′-unsaturated or 3′-modified]-pyrimidine nucleosides
US5703058A (en) * 1995-01-27 1997-12-30 Emory University Compositions containing 5-fluoro-2',3'-didehydro-2',3'-dideoxycytidine or a mono-, di-, or triphosphate thereof and a second antiviral agent
US5808040A (en) * 1995-01-30 1998-09-15 Yale University L-nucleosides incorporated into polymeric structure for stabilization of oligonucleotides
US5753789A (en) * 1996-07-26 1998-05-19 Yale University Oligonucleotides containing L-nucleosides
AU727177B2 (en) * 1996-10-16 2000-12-07 Icn Pharmaceuticals, Inc. Purine L-nucleosides, analogs and uses thereof
RU2358979C2 (ru) 2003-05-30 2009-06-20 Фармассет, Инк. Модифицированные фторированные аналоги нуклеозида
CN101023094B (zh) 2004-07-21 2011-05-18 法莫赛特股份有限公司 烷基取代的2-脱氧-2-氟代-d-呋喃核糖基嘧啶和嘌呤及其衍生物的制备
ES2725457T3 (es) 2004-09-14 2019-09-24 Gilead Pharmasset Llc Preparación de ribofuranosil pirimidinas y purinas 2'fluoro-2'-alquil-sustituidas u otras opcionalmente sustituidas y sus derivados
US8233581B2 (en) 2009-03-31 2012-07-31 Westinghouse Electric Company Llc Process for adding an organic compound to coolant water in a pressurized water reactor
EP2454532B1 (en) 2009-07-17 2018-09-12 Technical University of Denmark Device and method for reducing spread of microorganisms and airborne health hazardous matter and/or for protection from microorganisms and airborne health hazardous matter
JP5756111B2 (ja) 2009-09-10 2015-07-29 ノースイースタン ユニバーシティ 炭化コバルト系ナノ粒子永久磁石材料
AU2011220329B2 (en) 2010-02-24 2016-11-24 Hydrexia Pty Ltd Hydrogen release system
DE102010023188A1 (de) 2010-06-09 2011-12-15 D. Brown Traktoren Gmbh Lader für Verbrennungsmotoren
JP6111323B2 (ja) 2012-04-19 2017-04-05 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト 血液中の検体濃度を測定する方法および装置
DE102014222078A1 (de) 2013-10-31 2015-04-30 Emery Oleochemicals Gmbh Trennmittel, insbesondere Entformungshilfsmittel, Verfahren zur Herstellung des Trennmittels und Verwendung des Trennmittels
EP3080364B1 (en) 2013-12-15 2019-02-20 VKR Holding A/S Skylight with sunlight pivot
US20150204231A1 (en) 2014-01-22 2015-07-23 Fpt Industrial S.P.A. System for pressurizing a cooling circuit of an internal combustion engine equipped with a turbocompressor unit

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT82580B (pt) * 1985-05-15 1989-01-17 Wellcome Found Processo para a preparacao de 2',3'- didesoxinucleosidos e de composicoes farmaceuticas que os contem

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09505306A (ja) * 1993-11-16 1997-05-27 ジンタ・インコーポレイテッド 非ホスホネートヌクレオシド間結合と混合している不確定キラリティーのホスホネートヌクレオシド間結合を有する合成オリゴマー
US9854811B2 (en) * 2006-11-16 2018-01-02 Coats Agri Aloe, Llc Treatment of plants, fruits and vegetables to increase growth, eliminate insects and increase shelf-life with aloe vera gel
US9653313B2 (en) 2013-05-01 2017-05-16 Sensor Electronic Technology, Inc. Stress relieving semiconductor layer
US9771634B2 (en) 2014-11-05 2017-09-26 Companhia Brasileira De Metalurgia E Mineração Processes for producing low nitrogen essentially nitride-free chromium and chromium plus niobium-containing nickel-based alloys and the resulting chromium and nickel-based alloys
CN104977079A (zh) * 2015-06-29 2015-10-14 北京航天易联科技发展有限公司 一种信号解调方法和装置
CN104950133A (zh) * 2015-07-06 2015-09-30 浙江大学 微流体流速传感芯片、检测系统及检测方法
NO20160930A1 (en) * 2016-05-31 2017-12-01 Inst Energiteknik Method, powder, film, electrode & battery

Also Published As

Publication number Publication date
EP0285884A3 (en) 1990-07-04
IL85778A0 (en) 1988-09-30
EP0285884A2 (en) 1988-10-12

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