LT2661B - Peptidilglicinines alpha-amiduojancios monooksigenazes isvalymo budas ir alpha-amiduoto peptido gavimo budas - Google Patents

Peptidilglicinines alpha-amiduojancios monooksigenazes isvalymo budas ir alpha-amiduoto peptido gavimo budas

Info

Publication number
LT2661B
LT2661B LTRP1130A LTRP1130A LT2661B LT 2661 B LT2661 B LT 2661B LT RP1130 A LTRP1130 A LT RP1130A LT RP1130 A LTRP1130 A LT RP1130A LT 2661 B LT2661 B LT 2661B
Authority
LT
Lithuania
Prior art keywords
alpha
enzyme
peptidilglic
monooksigenaze
amided
Prior art date
Application number
LTRP1130A
Other languages
English (en)
Lithuanian (lt)
Inventor
James P Gilligan
Barry N Drive
Original Assignee
Unigene Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24628603&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LT2661(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Unigene Lab Inc filed Critical Unigene Lab Inc
Publication of LT2661B publication Critical patent/LT2661B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/17—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with reduced ascorbate as one donor, and incorporation of one atom of oxygen (1.14.17)
    • C12Y114/17003—Peptidylglycine monooxygenase (1.14.17.3)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
LTRP1130A 1984-09-27 1993-09-27 Peptidilglicinines alpha-amiduojancios monooksigenazes isvalymo budas ir alpha-amiduoto peptido gavimo budas LT2661B (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/655,366 US4708934A (en) 1984-09-27 1984-09-27 α-amidation enzyme

Publications (1)

Publication Number Publication Date
LT2661B true LT2661B (lt) 1994-04-25

Family

ID=24628603

Family Applications (1)

Application Number Title Priority Date Filing Date
LTRP1130A LT2661B (lt) 1984-09-27 1993-09-27 Peptidilglicinines alpha-amiduojancios monooksigenazes isvalymo budas ir alpha-amiduoto peptido gavimo budas

Country Status (13)

Country Link
US (1) US4708934A (de)
EP (1) EP0201511B1 (de)
JP (1) JP2594037B2 (de)
AT (1) ATE92522T1 (de)
CA (1) CA1341037C (de)
DE (1) DE3587506T2 (de)
DK (1) DK241486D0 (de)
FI (1) FI100993B1 (de)
HU (1) HU195857B (de)
LT (1) LT2661B (de)
NO (1) NO862100L (de)
RU (1) RU1802814C (de)
WO (1) WO1986002099A1 (de)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6319685B1 (en) * 1984-09-27 2001-11-20 Unigene Laboratories, Inc. Alpha-amidating enzyme compositions and processes for their production and use
DE3612302A1 (de) * 1986-04-11 1987-10-15 Hoechst Ag Chromophore peptide, verfahren zu ihrer herstellung und ihre verwendung zum nachweis der peptidylglycin-(alpha)-amidierenden monooxygenase
JPH0775541B2 (ja) * 1986-06-07 1995-08-16 壽之 松尾 Ｃ末端アミド化酵素及びその製造方法
US5821083A (en) * 1987-07-17 1998-10-13 Suntory Limited Recombinant C-terminal α-amidating enzyme
JP2598050B2 (ja) * 1987-07-17 1997-04-09 サントリー株式会社 Ｃ−末端α−アミド化酵素
US5789234A (en) * 1987-08-14 1998-08-04 Unigene Laboratories, Inc. Expression systems for amidating enzyme
US6255067B1 (en) * 1987-09-15 2001-07-03 The Johns Hopkins University cDNA encoding peptidyl-glycine alpha-amidating monooxygenase (PAM)
JP2653820B2 (ja) * 1988-03-14 1997-09-17 壽之 松尾 アミド化酵素及びその製造方法
JP2512575B2 (ja) * 1988-05-30 1996-07-03 株式会社資生堂 Ｃ末端アミド化酵素組成物、調製方法および使用
DE68917154T2 (de) * 1988-05-30 1994-12-22 Shiseido Co Ltd C-terminus-amidierungsenzym-zusammensetzung, verfahren zur herstellung und verwendung.
JP2845468B2 (ja) * 1989-01-17 1999-01-13 サントリー株式会社 ヒト甲状腺由来Ｃ―末端α―アミド化酵素
US5871995A (en) * 1989-08-15 1999-02-16 Shiseido Company, Ltd. Purified enzymes participating in C-terminal amidation
EP0448513A3 (en) * 1990-03-21 1991-12-27 Japat Ltd Process for production of peptidylglycine alpha-hydroxylating monooxygenase and use thereof
DK220890D0 (da) * 1990-09-14 1990-09-14 Ole Buchardt Fremgangsmaade til fremstilling af c-terminalt amiderede peptider
US5580751A (en) * 1990-09-14 1996-12-03 Carlsberg A/S Process for the preparation of C-terminally amidated peptides
JP2774769B2 (ja) * 1993-04-26 1998-07-09 賢治 寒川 アドレノメデュリン
WO1997013410A1 (en) * 1995-10-13 1997-04-17 Boston Medical Center Corporation Hybrid molecules containing amidated polypeptide binding ligands
US5912014A (en) * 1996-03-15 1999-06-15 Unigene Laboratories, Inc. Oral salmon calcitonin pharmaceutical products
WO1998046722A1 (en) 1997-04-16 1998-10-22 Unigene Laboratories Inc. Direct expression of peptides into culture media
US6507788B1 (en) 1999-02-25 2003-01-14 Société de Conseils de Recherches et D'Applications Scientifiques (S.C.R.A.S.) Rational selection of putative peptides from identified nucleotide, or peptide sequences, of unknown function
US8088734B2 (en) * 2003-01-21 2012-01-03 Unigene Laboratories Inc. Oral delivery of peptides
US7445911B2 (en) * 2004-11-24 2008-11-04 Unigene Laboratories Inc. Enzymatic reactions in the presence of keto acids
DE102004058306A1 (de) * 2004-12-01 2006-07-27 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von Carboxy-terminal amidierten Peptiden
PA8660701A1 (es) 2005-02-04 2006-09-22 Pfizer Prod Inc Agonistas de pyy y sus usos
AU2006261909B2 (en) 2005-06-24 2011-08-11 Enteris Biopharma, Inc. Cell lines for expressing enzyme useful in the preparation of amidated products
US8377863B2 (en) 2007-05-29 2013-02-19 Unigene Laboratories Inc. Peptide pharmaceutical for oral delivery
CA2691374A1 (en) * 2007-06-29 2009-01-08 Asubio Pharma Co., Ltd. Recombinant c-terminal .alpha.-amidating enzyme derivative
ES2622877T3 (es) 2009-01-22 2017-07-07 Keybioscience Ag Tratamiento para la obesidad
WO2011067283A1 (en) 2009-12-01 2011-06-09 Novo Nordisk A/S Novel peptidyl alpha-hydroxyglycine alpha-amidating lyases
TW201138808A (en) 2010-05-03 2011-11-16 Bristol Myers Squibb Co Serum albumin binding molecules
US9102753B2 (en) 2011-06-15 2015-08-11 Ugp Therapeutics, Inc. Anti-inflammatory pharmaceutical products
US9533022B2 (en) 2011-11-02 2017-01-03 KeyBioscience A/S Peptide analogs for treating diseases and disorders
US9006172B2 (en) 2011-11-02 2015-04-14 Keybioscience Ag Peptide analogs for treating diseases and disorders
EP3357540A1 (de) 2011-11-02 2018-08-08 KeyBioscience AG Zusammensetzung aus einen calcitoninmimetika und einen nsulin-sensibilisator
CN105722854B (zh) 2013-11-14 2020-08-04 关键生物科学有限公司 用于治疗疾病和病症的降钙素模拟物
JP2016540762A (ja) 2013-12-02 2016-12-28 ステルス バイオセラピューティックス コープ 白斑の治療のための組成物及び方法
EP3502132A1 (de) 2014-05-28 2019-06-26 Stealth BioTherapeutics Corp Therapeutische zusammensetzungen mit kleinen therapeutischen molekülen und verwendungen davon
WO2015183995A2 (en) 2014-05-28 2015-12-03 Stealth Peptides International, Inc. Therapeutic compositions including frataxin, lactoferrin, and mitochondrial energy generating enzymes, and uses thereof
US10627392B2 (en) 2014-06-17 2020-04-21 Stealth Biotherapeutics Corp Methods of identifying and monitoring mitochondrial dysfunction using monocyte screening
GB201500263D0 (en) 2015-01-08 2015-02-25 Keybioscience Ag Calcitonin analogues for treating diseases and disorders
DK3244878T3 (da) 2015-01-12 2022-10-17 Enteris Biopharma Inc Faste orale sammensætningsformer
ES2876947T3 (es) 2015-02-13 2021-11-15 Univ Illinois Inhibición con péptidos de enfermedades o afecciones mediadas por CCR3
GB201704429D0 (en) 2017-03-21 2017-05-03 Keybioscience Ag Calcitonin mimetics for treating diseases and disorders
GB201707955D0 (en) 2017-05-18 2017-07-05 Keybioscience Ag Dual amylin and calcitonin receptor agonists for treating diseases and disorders
GB201813677D0 (en) 2018-08-22 2018-10-03 Keybioscience Ag Calcitonin mimetics for treating diseases and disorders
GB201813678D0 (en) 2018-08-22 2018-10-03 Keybioscience Ag Acylated calcitonin mimetics
JP7636812B2 (ja) 2019-07-29 2025-02-27 ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティ オブ イリノイ 創傷治癒を促進するための組成物および方法
GB202001024D0 (en) 2020-01-24 2020-03-11 Key Bioscience Ag Oxyntomodulin mimetics
US20230097988A1 (en) * 2020-02-26 2023-03-30 Pam Theragnostics Gmbh Methods for determining peptidylglycine alpha-amidating monooxygenase (pam) and its use for diagnostic purpose
IL295924A (en) * 2020-02-26 2022-10-01 Pam Theragnostics Gmbh Use of peptidylglycine alpha-amidization monooxygenase (pam) for medicinal purposes
CN119144573B (zh) * 2024-11-20 2025-04-01 齐鲁工业大学(山东省科学院) 一种多肽模拟酶、固定化模拟酶及其在afb1降解上的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6319685B1 (en) * 1984-09-27 2001-11-20 Unigene Laboratories, Inc. Alpha-amidating enzyme compositions and processes for their production and use

Also Published As

Publication number Publication date
HU195857B (en) 1988-07-28
NO175214B (de) 1994-06-06
DK241486A (da) 1986-05-23
EP0201511A1 (de) 1986-11-20
NO175214C (de) 1994-09-14
DE3587506D1 (en) 1993-09-09
FI100993B1 (fi) 1998-03-31
FI94361C (fi) 1995-08-25
HUT41444A (en) 1987-04-28
EP0201511A4 (de) 1988-05-31
US4708934A (en) 1987-11-24
AU594026B2 (en) 1990-03-01
RU1802814C (ru) 1993-03-15
WO1986002099A1 (en) 1986-04-10
CA1341037C (en) 2000-06-27
JP2594037B2 (ja) 1997-03-26
DE3587506T2 (de) 1994-01-13
ATE92522T1 (de) 1993-08-15
JPS62500560A (ja) 1987-03-12
DK241486D0 (da) 1986-05-23
EP0201511B1 (de) 1993-08-04
FI862216A0 (fi) 1986-05-26
FI862216A7 (fi) 1986-05-26
AU4802785A (en) 1986-04-17
NO862100L (no) 1986-05-27
FI94361B (fi) 1995-05-15

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Effective date: 20000826