LT3193611T - Mk2 inhibitoriai ir jų panaudojimas - Google Patents

Mk2 inhibitoriai ir jų panaudojimas

Info

Publication number
LT3193611T
LT3193611T LTEP15842903.5T LT15842903T LT3193611T LT 3193611 T LT3193611 T LT 3193611T LT 15842903 T LT15842903 T LT 15842903T LT 3193611 T LT3193611 T LT 3193611T
Authority
LT
Lithuania
Prior art keywords
inhibitors
Prior art date
Application number
LTEP15842903.5T
Other languages
English (en)
Lithuanian (lt)
Inventor
Matthew David Alexander
Claudio Chuaqui
John MALONA
Joseph John MCDONALD
Yike Ni
Deqiang Niu
Russell C. Petter
Juswinder Singh
Chittari Pabba
Original Assignee
Celgene Car Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Car Llc filed Critical Celgene Car Llc
Publication of LT3193611T publication Critical patent/LT3193611T/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Enzymes And Modification Thereof (AREA)
LTEP15842903.5T 2014-09-17 2015-09-16 Mk2 inhibitoriai ir jų panaudojimas LT3193611T (lt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462051788P 2014-09-17 2014-09-17
US201562199927P 2015-07-31 2015-07-31
PCT/US2015/050495 WO2016044463A2 (en) 2014-09-17 2015-09-16 Mk2 inhibitors and uses thereof

Publications (1)

Publication Number Publication Date
LT3193611T true LT3193611T (lt) 2021-08-25

Family

ID=55454109

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP15842903.5T LT3193611T (lt) 2014-09-17 2015-09-16 Mk2 inhibitoriai ir jų panaudojimas

Country Status (30)

Country Link
US (5) US9458175B2 (2)
EP (2) EP3912981A1 (2)
JP (3) JP6556225B2 (2)
KR (1) KR102457848B1 (2)
CN (1) CN106998692B (2)
AU (1) AU2015317741B2 (2)
BR (1) BR112017005266B1 (2)
CA (1) CA2961607C (2)
CL (1) CL2017000576A1 (2)
CO (1) CO2017003279A2 (2)
CY (1) CY1124215T1 (2)
DK (1) DK3193611T3 (2)
EA (1) EA037299B1 (2)
EC (1) ECSP17023281A (2)
ES (1) ES2874561T3 (2)
HR (1) HRP20210529T1 (2)
HU (1) HUE054347T2 (2)
IL (1) IL251051B (2)
LT (1) LT3193611T (2)
MA (1) MA40534B1 (2)
MX (2) MX373341B (2)
PL (1) PL3193611T3 (2)
PT (1) PT3193611T (2)
RS (1) RS62017B1 (2)
SA (1) SA517381115B1 (2)
SG (2) SG11201701861RA (2)
SI (1) SI3193611T1 (2)
SM (1) SMT202100311T1 (2)
TW (1) TWI744217B (2)
WO (1) WO2016044463A2 (2)

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US10882867B2 (en) * 2017-03-16 2021-01-05 Celgene Car Llc Forms and compositions of a MK2 inhibitor
US11230551B2 (en) 2017-03-16 2022-01-25 Celgene Car Llc Deuterated analogs of MK2 inhibitors and uses thereof
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EP4608401A2 (en) * 2022-10-27 2025-09-03 Bristol-Myers Squibb Company Mk2 inhibitors and uses thereof
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WO2024229401A2 (en) * 2023-05-04 2024-11-07 Matchpoint Therapeutics Inc. Diazepino-thieno-quinoxaline compounds and their use in therapy
CN121368484A (zh) * 2023-06-26 2026-01-20 深圳信立泰药业股份有限公司 一种mk2抑制剂在制备预防和/或治疗疾病药物中的应用

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Also Published As

Publication number Publication date
SMT202100311T1 (it) 2021-07-12
US20210053984A1 (en) 2021-02-25
PL3193611T3 (pl) 2021-10-04
JP6556225B2 (ja) 2019-08-07
JP7375072B2 (ja) 2023-11-07
ECSP17023281A (es) 2017-06-30
AU2015317741A1 (en) 2017-04-20
EP3193611A4 (en) 2018-02-28
DK3193611T3 (da) 2021-05-10
EA037299B1 (ru) 2021-03-05
KR20170063734A (ko) 2017-06-08
BR112017005266B1 (pt) 2022-11-01
EP3193611B1 (en) 2021-03-24
CN106998692B (zh) 2020-09-08
SG11201701861RA (en) 2017-04-27
US9790235B2 (en) 2017-10-17
CY1124215T1 (el) 2022-05-27
EP3912981A1 (en) 2021-11-24
CN106998692A (zh) 2017-08-01
AU2015317741B2 (en) 2020-01-16
CO2017003279A2 (es) 2017-09-29
PT3193611T (pt) 2021-05-28
US20170114073A1 (en) 2017-04-27
US10253040B1 (en) 2019-04-09
JP2017529367A (ja) 2017-10-05
MX373341B (es) 2020-05-26
MX2017003359A (es) 2017-11-22
SA517381115B1 (ar) 2021-03-09
US10577380B2 (en) 2020-03-03
BR112017005266A2 (pt) 2017-12-12
TWI744217B (zh) 2021-11-01
CA2961607A1 (en) 2016-03-24
RS62017B1 (sr) 2021-07-30
CL2017000576A1 (es) 2017-12-01
MA40534B1 (fr) 2021-04-30
WO2016044463A3 (en) 2016-09-01
EA201790380A1 (ru) 2017-08-31
EP3193611A2 (en) 2017-07-26
JP2019194236A (ja) 2019-11-07
CA2961607C (en) 2023-03-28
WO2016044463A2 (en) 2016-03-24
MX2020005213A (es) 2020-08-20
ES2874561T3 (es) 2021-11-05
HRP20210529T1 (hr) 2021-08-06
US9458175B2 (en) 2016-10-04
IL251051A0 (en) 2017-04-30
KR102457848B1 (ko) 2022-10-25
US20190375762A1 (en) 2019-12-12
NZ730603A (en) 2024-02-23
SG10201902326XA (en) 2019-04-29
TW201617351A (zh) 2016-05-16
JP2022078315A (ja) 2022-05-24
HUE054347T2 (hu) 2021-08-30
SI3193611T1 (sl) 2021-08-31
US11584757B2 (en) 2023-02-21
US20160075720A1 (en) 2016-03-17
MA40534A (fr) 2016-03-24
IL251051B (en) 2019-11-28

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