LT3619199T - 2-([1,2,3]triazol-2-il)-benzenkarboksirūgšties darinių gamyba - Google Patents

2-([1,2,3]triazol-2-il)-benzenkarboksirūgšties darinių gamyba

Info

Publication number
LT3619199T
LT3619199T LTEPPCT/EP2018/061172T LT18722948T LT3619199T LT 3619199 T LT3619199 T LT 3619199T LT 18722948 T LT18722948 T LT 18722948T LT 3619199 T LT3619199 T LT 3619199T
Authority
LT
Lithuania
Prior art keywords
triazol
preparation
benzoic acid
acid derivatives
derivatives
Prior art date
Application number
LTEPPCT/EP2018/061172T
Other languages
English (en)
Inventor
Patric DÖRRWÄCHTER
Gunther Schmidt
Original Assignee
Idorsia Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idorsia Pharmaceuticals Ltd filed Critical Idorsia Pharmaceuticals Ltd
Publication of LT3619199T publication Critical patent/LT3619199T/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C07D249/06—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/70—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of the iron group metals or copper
    • B01J23/72—Copper
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
LTEPPCT/EP2018/061172T 2017-05-03 2018-05-02 2-([1,2,3]triazol-2-il)-benzenkarboksirūgšties darinių gamyba LT3619199T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP2017060451 2017-05-03
PCT/EP2018/061172 WO2018202689A1 (en) 2017-05-03 2018-05-02 Preparation of 2-([1,2,3]triazol-2-yl)-benzoic acid derivatives

Publications (1)

Publication Number Publication Date
LT3619199T true LT3619199T (lt) 2021-09-27

Family

ID=62116854

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEPPCT/EP2018/061172T LT3619199T (lt) 2017-05-03 2018-05-02 2-([1,2,3]triazol-2-il)-benzenkarboksirūgšties darinių gamyba

Country Status (20)

Country Link
US (1) US11124488B2 (lt)
EP (1) EP3619199B1 (lt)
JP (1) JP7182562B2 (lt)
KR (1) KR102582197B1 (lt)
CN (1) CN110612291B (lt)
CA (1) CA3059394C (lt)
CY (1) CY1124777T1 (lt)
DK (1) DK3619199T3 (lt)
ES (1) ES2892161T3 (lt)
HR (1) HRP20211304T1 (lt)
HU (1) HUE055904T2 (lt)
IL (1) IL270274B (lt)
LT (1) LT3619199T (lt)
MX (1) MX392154B (lt)
PL (1) PL3619199T3 (lt)
PT (1) PT3619199T (lt)
RS (1) RS62357B1 (lt)
SI (1) SI3619199T1 (lt)
TW (1) TWI756418B (lt)
WO (1) WO2018202689A1 (lt)

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MX2022011179A (es) 2020-04-19 2022-10-07 Idorsia Pharmaceuticals Ltd Uso medico de daridorexant.
WO2023218023A1 (en) 2022-05-13 2023-11-16 Idorsia Pharmaceuticals Ltd Thiazoloaryl-methyl substituted cyclic hydrazine-n-carboxamide derivatives
CN117736193B (zh) * 2023-12-19 2024-07-23 南京知和医药科技有限公司 一种氘代稠环化合物及其制备方法与用途
ES3038762B2 (es) * 2024-04-12 2026-06-24 Moehs Iberica Sl Procedimiento de síntesis de ácido 5-metoxi-2-(2H-1,2,3-triazol-2yl)benzoico, sal sódica de dicho ácido como intermedio de síntesis y uso del ácido o de su sal en la preparación de daridorexant y ciertos intermedios en la síntesis del mismo
CN121974861B (zh) * 2026-04-02 2026-06-09 华中科技大学同济医学院附属同济医院 一种4-（1h-1,2,3-三唑-1-基）苯甲酸类化合物及其制备方法和应用

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PE20081229A1 (es) 2006-12-01 2008-08-28 Merck & Co Inc Antagonistas de receptor de orexina de diazepam sustituido
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SI2776430T1 (sl) 2011-11-08 2016-06-30 Actelion Pharmaceuticals Ltd. 2-(1,2,3-triazol-2-il)benzamidni in 3-(1,2,3-triazol-2-il)pikolinamidni derivati kot antagonisti oreksinskega receptorja
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TW201444849A (zh) 2013-03-13 2014-12-01 Janssen Pharmaceutica Nv 經取代的7-氮雜雙環類及其作為食慾激素受體調節劑之用途
TW201444821A (zh) 2013-03-13 2014-12-01 Janssen Pharmaceutica Nv 經取代之哌啶化合物及其作為食慾素受體調節劑之用途
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UA119151C2 (uk) 2013-12-03 2019-05-10 Ідорсія Фармасьютікалз Лтд КРИСТАЛІЧНА СОЛЬОВА ФОРМА (S)-(2-(6-ХЛОР-7-МЕТИЛ-1H-БЕНЗО[d]ІМІДАЗОЛ-2-ІЛ)-2-МЕТИЛПІРОЛІДИН-1-ІЛ)(5-МЕТОКСИ-2-(2H-1,2,3-ТРИАЗОЛ-2-ІЛ)ФЕНІЛ)МЕТАНОНУ ЯК АНТАГОНІСТ ОРЕКСИНОВОГО РЕЦЕПТОРА
SI3077391T1 (sl) 2013-12-04 2018-11-30 Idorsia Pharmaceuticals Ltd Uporaba benzimidazol-prolinskih derivatov
TW201613891A (en) 2014-02-12 2016-04-16 Eolas Therapeutics Inc Substituted prolines / piperidines as orexin receptor antagonists
WO2016020403A1 (en) 2014-08-04 2016-02-11 Sandoz Ag Preparation of a benzoic acid derivative and its use for the preparation of suvorexant
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WO2016171248A1 (ja) 2015-04-24 2016-10-27 武田薬品工業株式会社 複素環化合物

Also Published As

Publication number Publication date
HUE055904T2 (hu) 2021-12-28
CN110612291A (zh) 2019-12-24
US11124488B2 (en) 2021-09-21
ES2892161T3 (es) 2022-02-02
US20210114997A1 (en) 2021-04-22
DK3619199T3 (da) 2021-09-27
EP3619199B1 (en) 2021-07-07
PL3619199T3 (pl) 2021-12-20
MX2019012902A (es) 2019-12-16
IL270274A (lt) 2019-12-31
TWI756418B (zh) 2022-03-01
JP7182562B2 (ja) 2022-12-02
TW201843144A (zh) 2018-12-16
IL270274B (en) 2022-08-01
MX392154B (es) 2025-03-21
CA3059394C (en) 2023-09-12
WO2018202689A1 (en) 2018-11-08
PT3619199T (pt) 2021-10-01
CA3059394A1 (en) 2018-11-08
KR20200003097A (ko) 2020-01-08
RS62357B1 (sr) 2021-10-29
KR102582197B1 (ko) 2023-09-22
CY1124777T1 (el) 2022-11-25
SI3619199T1 (sl) 2021-11-30
HRP20211304T1 (hr) 2021-11-12
EP3619199A1 (en) 2020-03-11
CN110612291B (zh) 2024-02-13
JP2020518573A (ja) 2020-06-25

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