LT3657B - Process for preparing imidazole derivatives - Google Patents

Process for preparing imidazole derivatives Download PDF

Info

Publication number
LT3657B
LT3657B LTIP847A LTIP847A LT3657B LT 3657 B LT3657 B LT 3657B LT IP847 A LTIP847 A LT IP847A LT IP847 A LTIP847 A LT IP847A LT 3657 B LT3657 B LT 3657B
Authority
LT
Lithuania
Prior art keywords
formula
compound
pharmaceutically acceptable
acceptable salt
preparation
Prior art date
Application number
LTIP847A
Other languages
English (en)
Lithuanian (lt)
Inventor
Arto Johannes Karjalainen
Reino Olavi Pelkonen
Marja-Liisa Soedervall
Matti Antero Laehde
Risto Arvo Sakari Lammintausta
Arja Leena Karjalainen
Arja Marketta Kalapudas
Original Assignee
Orion Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy
Publication of LTIP847A publication Critical patent/LTIP847A/xx
Publication of LT3657B publication Critical patent/LT3657B/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
LTIP847A 1989-03-30 1993-08-10 Process for preparing imidazole derivatives LT3657B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8907218A GB2229719B (en) 1989-03-30 1989-03-30 Novel aromatase inhibiting 4(5)-imidazoles

Publications (2)

Publication Number Publication Date
LTIP847A LTIP847A (en) 1995-02-27
LT3657B true LT3657B (en) 1996-01-25

Family

ID=10654204

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP847A LT3657B (en) 1989-03-30 1993-08-10 Process for preparing imidazole derivatives

Country Status (9)

Country Link
CA (1) CA2013395A1 (pl)
DD (1) DD296916A5 (pl)
FI (1) FI901316A7 (pl)
GB (1) GB2229719B (pl)
LT (1) LT3657B (pl)
PL (1) PL162554B1 (pl)
RU (2) RU2021263C1 (pl)
UA (1) UA19310A1 (pl)
ZA (1) ZA902479B (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2248058B (en) * 1990-09-21 1994-09-14 Orion Yhtymae Oy Aromatase inhibiting 4(5)-imidazoles
EP0943333A1 (de) * 1998-03-18 1999-09-22 S.W. Patentverwertungs GmbH Medikament zur Prophylaxe und/oder Behandlung des Mammakarzinoms enthaltend einen Hemmer der Bildung von Oestrogenen
DE102006019906A1 (de) * 2006-04-28 2007-10-31 Müller-Enoch, Dieter, Prof. Dr. Verwendung von Verbindungen der Formel A-R-X oder deren pharmazeutisch akzeptable Salze zur Herstellung einer pharmazeutischen Zubereitung
US20080146523A1 (en) * 2006-12-18 2008-06-19 Guido Galley Imidazole derivatives

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3759944A (en) 1970-10-14 1973-09-18 Smith Kline French Lab Isothioureas and their derivatives
EP0311447A1 (en) 1987-10-09 1989-04-12 Orion-Yhtymà„ Oy Aromatase inhibiting 4(5)-imidazoles
EP0390558A1 (en) 1989-03-30 1990-10-03 Orion-Yhtymà„ Oy Aromatase inhibiting 4(5)-imidazoles

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2101114B (en) * 1981-07-10 1985-05-22 Farmos Group Ltd Substituted imidazole derivatives and their preparation and use
CA1238640A (en) * 1984-06-18 1988-06-28 Kenneth S. Hirsch 4(5)-substituted imidazoles
LU85747A1 (fr) * 1985-01-28 1986-08-04 Continental Pharma Derives d'imidazole leur preparation et utilisation ainsi que les compositions pharmaceutiques contenant des derives

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3759944A (en) 1970-10-14 1973-09-18 Smith Kline French Lab Isothioureas and their derivatives
EP0311447A1 (en) 1987-10-09 1989-04-12 Orion-Yhtymà„ Oy Aromatase inhibiting 4(5)-imidazoles
EP0390558A1 (en) 1989-03-30 1990-10-03 Orion-Yhtymà„ Oy Aromatase inhibiting 4(5)-imidazoles

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ALLAN LIPTON MD ET AL.: "Aromatase activity in primary and metastatic human breast cancer", CANCER, 1987, pages 779 - 782
M. PASANEN: "Human placental aromatase activity: use of a C18 reversed-phase cartridge for separation of tritiated water or steroid metabolites in placentas from both smoking and non-smoking mothers in vitro", BIOLOGICAL RESEARCH IN PREGNANCY AND PERINATOLOGY, 1985, pages 94 - 99

Also Published As

Publication number Publication date
LTIP847A (en) 1995-02-27
PL162554B1 (pl) 1993-12-31
PL288962A1 (en) 1991-10-21
DD296916A5 (de) 1991-12-19
UA19310A1 (uk) 1997-12-25
FI901316A0 (fi) 1990-03-16
FI901316A7 (fi) 1990-10-01
GB8907218D0 (en) 1989-05-10
ZA902479B (en) 1990-12-28
RU1836355C (ru) 1993-08-23
GB2229719B (en) 1992-04-29
RU2021263C1 (ru) 1994-10-15
GB2229719A (en) 1990-10-03
CA2013395A1 (en) 1991-09-29

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Legal Events

Date Code Title Description
MM9A Lapsed patents

Effective date: 19970810