LT3841101T - 2-[(3r)-3-metilmorfolin-4-il]-4-[1-metil-1h-pirazol-5-il)-8-(1h pirazol-5-il)-1,7-naftiridino gavimo būdas - Google Patents

2-[(3r)-3-metilmorfolin-4-il]-4-[1-metil-1h-pirazol-5-il)-8-(1h pirazol-5-il)-1,7-naftiridino gavimo būdas

Info

Publication number
LT3841101T
LT3841101T LTEPPCT/EP2019/072467T LTEP2019072467T LT3841101T LT 3841101 T LT3841101 T LT 3841101T LT EP2019072467 T LTEP2019072467 T LT EP2019072467T LT 3841101 T LT3841101 T LT 3841101T
Authority
LT
Lithuania
Prior art keywords
pyrazol
methylmorpholin
naphthyridine
methyl
preparing
Prior art date
Application number
LTEPPCT/EP2019/072467T
Other languages
English (en)
Inventor
Johannes Platzek
Philipp Rubenbauer
Hendricus VAN DER HAAS
Sonja HOOGEVEEN
Matthijs VAN OERS
Reinerus Gieling
Jeroen Dekker
Original Assignee
Bayer Aktiengesellschaft
Bayer Pharma Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=63405064&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LT3841101(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Aktiengesellschaft, Bayer Pharma Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of LT3841101T publication Critical patent/LT3841101T/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
LTEPPCT/EP2019/072467T 2018-08-24 2019-08-22 2-[(3r)-3-metilmorfolin-4-il]-4-[1-metil-1h-pirazol-5-il)-8-(1h pirazol-5-il)-1,7-naftiridino gavimo būdas LT3841101T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18190731 2018-08-24
PCT/EP2019/072467 WO2020039025A1 (en) 2018-08-24 2019-08-22 Method for preparing 2-[(3r)-3-methylmorpholin-4-yl]-4-[1-methyl-1h-pyrazol-5-yl)-8-(1h-pyrazol-5-yl)-1,7-naphthyridine

Publications (1)

Publication Number Publication Date
LT3841101T true LT3841101T (lt) 2023-06-26

Family

ID=63405064

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEPPCT/EP2019/072467T LT3841101T (lt) 2018-08-24 2019-08-22 2-[(3r)-3-metilmorfolin-4-il]-4-[1-metil-1h-pirazol-5-il)-8-(1h pirazol-5-il)-1,7-naftiridino gavimo būdas

Country Status (28)

Country Link
US (1) US12258343B2 (lt)
EP (1) EP3841101B1 (lt)
JP (1) JP7422741B2 (lt)
KR (1) KR102797099B1 (lt)
CN (1) CN112823158B (lt)
AU (1) AU2019324521B9 (lt)
BR (1) BR112021001309A2 (lt)
CA (1) CA3110394A1 (lt)
CL (1) CL2021000454A1 (lt)
CO (1) CO2021001892A2 (lt)
DK (1) DK3841101T3 (lt)
ES (1) ES2950825T3 (lt)
FI (1) FI3841101T3 (lt)
HR (1) HRP20230611T1 (lt)
HU (1) HUE062332T2 (lt)
IL (1) IL280878A (lt)
JO (1) JOP20210032A1 (lt)
LT (1) LT3841101T (lt)
MX (1) MX2021002132A (lt)
MY (1) MY201874A (lt)
PE (1) PE20210862A1 (lt)
PL (1) PL3841101T3 (lt)
PT (1) PT3841101T (lt)
RS (1) RS64362B1 (lt)
SG (1) SG11202101011RA (lt)
SI (1) SI3841101T1 (lt)
UA (1) UA128407C2 (lt)
WO (1) WO2020039025A1 (lt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI656121B (zh) 2014-08-04 2019-04-11 德商拜耳製藥公司 ２－（嗎啉－４－基）－１，７－萘啶
EP3661560B1 (en) 2017-08-04 2025-02-26 Bayer Pharma Aktiengesellschaft Combination of atr kinase inhibitors and pd-1/pd-l1 inhibitors
US11236070B2 (en) 2019-05-16 2022-02-01 Novartis Ag Chemical process
JP2024529399A (ja) * 2021-07-19 2024-08-06 ヌマット テクノロジーズ インコーポレーテッド 液体組成物中の汚染物質を除去するためのプロセスおよび製品

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007107469A1 (en) * 2006-03-20 2007-09-27 F. Hoffmann-La Roche Ag Methods of inhibiting btk and syk protein kinases
EP2154965A4 (en) * 2007-05-29 2011-08-17 Glaxosmithkline Llc NAPHTHYRIDINE DERIVATIVES AS P13 KINASE INHIBITORS
JP5564045B2 (ja) * 2008-09-02 2014-07-30 ノバルティス アーゲー 二環式キナーゼ阻害剤
AU2012257513B2 (en) * 2011-05-19 2017-05-11 Fundación Del Sector Público Estatal Centro Nacional De Investigaciones Oncológicas Carlos III (F.S.P. CNIO) Macrocyclic compounds as protein kinase inhibitors
KR101366368B1 (ko) * 2011-07-08 2014-02-21 주식회사 두산 신규 유기 전계 발광 화합물 및 이를 포함하는 유기 전계 발광 소자
TWI656121B (zh) * 2014-08-04 2019-04-11 德商拜耳製藥公司 ２－（嗎啉－４－基）－１，７－萘啶
WO2018153970A1 (en) * 2017-02-24 2018-08-30 Bayer Pharma Aktiengesellschaft Solid forms of 2-[(3r)-3-methylmorpholin-4-yl]-4-(1-methyl-1h-pyrazol-5-yl)-8-(1h-pyrazol-5-yl)-1,7-naphthyridine

Also Published As

Publication number Publication date
AU2019324521A1 (en) 2021-03-11
PL3841101T3 (pl) 2023-08-21
CO2021001892A2 (es) 2021-03-08
AU2019324521B2 (en) 2024-10-31
IL280878A (en) 2021-04-29
SG11202101011RA (en) 2021-02-25
US12258343B2 (en) 2025-03-25
HRP20230611T1 (hr) 2023-09-15
MX2021002132A (es) 2021-04-28
KR20210049845A (ko) 2021-05-06
JP7422741B2 (ja) 2024-01-26
SI3841101T1 (sl) 2023-07-31
FI3841101T3 (fi) 2023-07-28
MY201874A (en) 2024-03-21
RS64362B1 (sr) 2023-08-31
WO2020039025A1 (en) 2020-02-27
CN112823158B (zh) 2023-08-15
BR112021001309A2 (pt) 2021-04-27
US20210253573A1 (en) 2021-08-19
JOP20210032A1 (ar) 2021-02-23
KR102797099B1 (ko) 2025-04-18
HUE062332T2 (hu) 2023-10-28
PT3841101T (pt) 2023-07-25
AU2019324521B9 (en) 2024-11-14
UA128407C2 (uk) 2024-07-03
PE20210862A1 (es) 2021-05-18
CN112823158A (zh) 2021-05-18
CL2021000454A1 (es) 2021-07-09
ES2950825T3 (es) 2023-10-13
EP3841101B1 (en) 2023-05-03
EP3841101A1 (en) 2021-06-30
CA3110394A1 (en) 2020-02-27
JP2021535122A (ja) 2021-12-16
DK3841101T3 (da) 2023-07-31

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