LT4214210T - Junginiai ir kompozicijos kaip sppl2a inhibitoriai - Google Patents

Junginiai ir kompozicijos kaip sppl2a inhibitoriai

Info

Publication number
LT4214210T
LT4214210T LTEPPCT/IB2021/058398T LTIB2021058398T LT4214210T LT 4214210 T LT4214210 T LT 4214210T LT IB2021058398 T LTIB2021058398 T LT IB2021058398T LT 4214210 T LT4214210 T LT 4214210T
Authority
LT
Lithuania
Prior art keywords
sppl2a
inhibitors
compositions
compounds
sppl2a inhibitors
Prior art date
Application number
LTEPPCT/IB2021/058398T
Other languages
English (en)
Inventor
Trixi Brandl
Claus Ehrhardt
Robert Epple
Christian Markert
Pascal Rigollier
Juraj Velcicky
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of LT4214210T publication Critical patent/LT4214210T/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
LTEPPCT/IB2021/058398T 2020-09-17 2021-09-15 Junginiai ir kompozicijos kaip sppl2a inhibitoriai LT4214210T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063079604P 2020-09-17 2020-09-17
PCT/IB2021/058398 WO2022058902A1 (en) 2020-09-17 2021-09-15 Compounds and compositions as sppl2a inhibitors

Publications (1)

Publication Number Publication Date
LT4214210T true LT4214210T (lt) 2025-07-25

Family

ID=77897680

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEPPCT/IB2021/058398T LT4214210T (lt) 2020-09-17 2021-09-15 Junginiai ir kompozicijos kaip sppl2a inhibitoriai

Country Status (31)

Country Link
US (1) US20230365571A1 (lt)
EP (2) EP4578451A3 (lt)
JP (2) JP7771172B2 (lt)
KR (1) KR20230069947A (lt)
CN (1) CN116615425B (lt)
AU (1) AU2021342783A1 (lt)
CA (1) CA3192763A1 (lt)
CL (2) CL2023000728A1 (lt)
CO (1) CO2023004646A2 (lt)
CR (1) CR20230142A (lt)
DK (1) DK4214210T3 (lt)
DO (1) DOP2023000055A (lt)
EC (1) ECSP23027092A (lt)
ES (1) ES3028668T3 (lt)
FI (1) FI4214210T3 (lt)
GE (2) GEP20257771B (lt)
HR (1) HRP20250562T1 (lt)
HU (1) HUE071569T2 (lt)
IL (2) IL300953B1 (lt)
JO (1) JOP20230044A1 (lt)
LT (1) LT4214210T (lt)
MA (1) MA61557B1 (lt)
MD (1) MD4214210T2 (lt)
MX (1) MX2023003122A (lt)
PE (1) PE20231099A1 (lt)
PL (1) PL4214210T3 (lt)
PT (1) PT4214210T (lt)
RS (1) RS66874B1 (lt)
SI (1) SI4214210T1 (lt)
SM (1) SMT202500216T1 (lt)
WO (1) WO2022058902A1 (lt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116947813A (zh) * 2023-07-06 2023-10-27 绍兴贝斯美化工股份有限公司 一种3-氯-4-氨基-1-(3-吡啶基)-1h-吡唑的制备方法
US20250263416A1 (en) 2024-02-15 2025-08-21 Incyte Corporation SPPL2a INHIBITORS

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2124503C1 (ru) * 1992-05-18 1999-01-10 И.Р.Сквибб энд Санз, Инк. Гетероциклические азотсодержащие производные карбоновой кислоты, способ их получения и фармацевтическая композиция
GB9612622D0 (en) 1996-06-17 1996-08-21 Zeneca Ltd Chemical process
US6432944B1 (en) 2000-07-06 2002-08-13 Bristol-Myers Squibb Company Benzodiazepinone β-amyloid inhibitors: arylacetamidoalanyl derivatives
CA2514733A1 (en) 2003-02-28 2004-09-16 Transform Pharmaceuticals, Inc. Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen
BRPI0513310A (pt) 2004-07-12 2008-05-06 Idun Pharmaceuticals Inc análogos de tetrapeptìdeo
MX2007011234A (es) * 2005-03-14 2007-11-12 Transtech Pharma Inc Derivados de benzazol, composiciones y metodos de uso en la forma de inhibidores de b-secretasa.
MX2007015419A (es) 2005-06-08 2008-02-21 Novartis Ag Compuestos organicos.
EP2152664B1 (en) * 2007-06-13 2014-09-03 Bristol-Myers Squibb Company Dipeptide analogs as coagulation factor inhibitors
WO2015160772A1 (en) 2014-04-15 2015-10-22 Janssen Pharmaceutica Nv Tetrahydro-benzoimidazolyl modulators of tgr5
CN106146508A (zh) * 2015-03-19 2016-11-23 浙江导明医药科技有限公司 优化的联合用药及其治疗癌症和自身免疫疾病的用途
US11512080B2 (en) * 2018-01-12 2022-11-29 Kymera Therapeutics, Inc. CRBN ligands and uses thereof

Also Published As

Publication number Publication date
IL300953A (en) 2023-04-01
PL4214210T3 (pl) 2025-08-18
EP4578451A2 (en) 2025-07-02
HRP20250562T1 (hr) 2025-07-04
ES3028668T3 (en) 2025-06-19
MA61557B1 (fr) 2025-05-30
JP2023541475A (ja) 2023-10-02
CO2023004646A2 (es) 2023-07-21
KR20230069947A (ko) 2023-05-19
EP4214210A1 (en) 2023-07-26
IL300953B1 (en) 2026-04-01
RS66874B1 (sr) 2025-06-30
IL327099A (en) 2026-05-01
JOP20230044A1 (ar) 2023-02-27
CN116615425B (zh) 2026-05-01
DOP2023000055A (es) 2023-06-15
EP4578451A3 (en) 2025-09-17
DK4214210T3 (da) 2025-06-10
FI4214210T3 (fi) 2025-05-26
PT4214210T (pt) 2025-05-22
AU2021342783A9 (en) 2024-09-12
CL2024001312A1 (es) 2024-10-11
MD4214210T2 (ro) 2025-10-31
SI4214210T1 (sl) 2025-07-31
CA3192763A1 (en) 2022-03-24
PE20231099A1 (es) 2023-07-18
SMT202500216T1 (it) 2025-07-22
HUE071569T2 (hu) 2025-09-28
JP2026041723A (ja) 2026-03-10
MX2023003122A (es) 2023-03-22
US20230365571A1 (en) 2023-11-16
AU2021342783A1 (en) 2023-05-18
GEAP202516217A (en) 2025-02-10
GEP20257771B (en) 2025-06-10
EP4214210B1 (en) 2025-04-09
ECSP23027092A (es) 2023-06-30
CN116615425A (zh) 2023-08-18
WO2022058902A1 (en) 2022-03-24
JP7771172B2 (ja) 2025-11-17
CR20230142A (es) 2023-08-25
CL2023000728A1 (es) 2023-12-15

Similar Documents

Publication Publication Date Title
GB202014160D0 (en) Senolytic compounds and compositions
SI3837256T1 (sl) Spojine sečnine in sestavki kot zaviralci smarca2/brm-atpaze
IL321319A (en) Compounds and preparations as c-kit kinase inhibitors
ZA202109737B (en) Compound used as kinase inhibitor and application thereof
GB202013432D0 (en) Compositions
EP4419511A4 (en) COMPOUNDS AND THEIR USE AS GPR183 INHIBITORS
IL304159A (en) A preparation containing bl-8040
IL315415A (en) The compositions containing eticarpant
HUE071569T2 (hu) Sppl2a inhibitor vegyületek és készítmények
GB202319994D0 (en) Compositions for use
PL4065661T3 (pl) Kompozycje
GB202015836D0 (en) Compositions
GB202105461D0 (en) Compositions
GB202102704D0 (en) Compositions
EP3962916A4 (en) PIM-KINAS INHIBITOR COMPOSITIONS AND THEIR USES
GB2610026B (en) Compositions
EP4433478A4 (en) COMPOUNDS USED AS BCL-2 INHIBITORS
IL287316A (en) compounds and preparations
HK40095943A (en) Compounds and compositions as sppl2a inhibitors
IL317852A (en) 3-βHSD1 inhibitors and compositions and uses thereof
GB202016697D0 (en) Compound and composition for use
HK40118470A (en) Compounds and compositions that inhibit pikfyve
HK40114341A (en) Compounds and their uses as gpr183 inhibitors
ZA202210764B (en) Compositions
GB202211117D0 (en) Compositions and methods for non-immunogenecity