LTC2502996I2 - Anti-FGF23 antikūnas ir jį apimanti farmacinė kompozicija - Google Patents

Anti-FGF23 antikūnas ir jį apimanti farmacinė kompozicija

Info

Publication number
LTC2502996I2
LTC2502996I2 LTPA2018508C LTPA2018508C LTC2502996I2 LT C2502996 I2 LTC2502996 I2 LT C2502996I2 LT PA2018508 C LTPA2018508 C LT PA2018508C LT PA2018508 C LTPA2018508 C LT PA2018508C LT C2502996 I2 LTC2502996 I2 LT C2502996I2
Authority
LT
Lithuania
Prior art keywords
pharmaceutical composition
fgf23 antibody
fgf23
antibody
pharmaceutical
Prior art date
Application number
LTPA2018508C
Other languages
English (en)
Original Assignee
Kyowa Hakko Kirin Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39690189&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LTC2502996(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kyowa Hakko Kirin Co., Ltd. filed Critical Kyowa Hakko Kirin Co., Ltd.
Publication of LTPA2018508I1 publication Critical patent/LTPA2018508I1/lt
Publication of LTC2502996I2 publication Critical patent/LTC2502996I2/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Nutrition Science (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
LTPA2018508C 2007-02-14 2018-08-01 Anti-FGF23 antikūnas ir jį apimanti farmacinė kompozicija LTC2502996I2 (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007034018 2007-02-14
EP08711707.3A EP2128253B1 (en) 2007-02-14 2008-02-14 Anti-fgf23 antibody and pharmaceutical composition comprising the same

Publications (2)

Publication Number Publication Date
LTPA2018508I1 LTPA2018508I1 (lt) 2018-09-10
LTC2502996I2 true LTC2502996I2 (lt) 2019-05-10

Family

ID=39690189

Family Applications (3)

Application Number Title Priority Date Filing Date
LTEP12170984.4T LT2502996T (lt) 2007-02-14 2008-02-14 Anti-fgf23 antikūnas ir jį apimanti farmacinė kompozicija
LTEP17152168.5T LT3181691T (lt) 2007-02-14 2008-02-14 Anti fgf23 antikūnas ir jį apimanti farmacinė kompozicija
LTPA2018508C LTC2502996I2 (lt) 2007-02-14 2018-08-01 Anti-FGF23 antikūnas ir jį apimanti farmacinė kompozicija

Family Applications Before (2)

Application Number Title Priority Date Filing Date
LTEP12170984.4T LT2502996T (lt) 2007-02-14 2008-02-14 Anti-fgf23 antikūnas ir jį apimanti farmacinė kompozicija
LTEP17152168.5T LT3181691T (lt) 2007-02-14 2008-02-14 Anti fgf23 antikūnas ir jį apimanti farmacinė kompozicija

Country Status (22)

Country Link
US (4) US7883705B2 (lt)
EP (3) EP2128253B1 (lt)
JP (1) JP4800396B2 (lt)
KR (1) KR101462291B1 (lt)
CN (2) CN101652476B (lt)
AU (1) AU2008215346B2 (lt)
CA (1) CA2677782C (lt)
CY (3) CY1118835T1 (lt)
DK (3) DK2128253T3 (lt)
ES (3) ES2625823T3 (lt)
FR (1) FR18C1032I2 (lt)
HR (2) HRP20170548T1 (lt)
HU (3) HUE031728T2 (lt)
LT (3) LT2502996T (lt)
LU (2) LUC00082I2 (lt)
NL (1) NL300945I2 (lt)
NO (1) NO2018025I1 (lt)
PL (3) PL2502996T3 (lt)
PT (3) PT2502996T (lt)
SI (2) SI2502996T1 (lt)
TW (1) TWI422593B (lt)
WO (1) WO2008099969A1 (lt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1310554B1 (en) * 2000-08-11 2010-05-26 Kyowa Hakko Kirin Co., Ltd. Polypeptides controlling phosphoric acid metabolism, calcium metabolism, calcification and vitamin d metabolism and dnas encoding the same
CN100519584C (zh) * 2001-12-28 2009-07-29 麒麟医药株式会社 抗成纤维细胞生长因子23的抗体
US7883705B2 (en) 2007-02-14 2011-02-08 Kyowa Hakko Kirin Co., Ltd. Anti FGF23 antibody and a pharmaceutical composition comprising the same
WO2012050673A1 (en) 2010-10-14 2012-04-19 Wisconsin Alumni Research Foundation Methods for the treatment of x-linked hypophosphatemia and related disorders
EP2723391B1 (en) 2011-06-24 2018-06-13 University of Miami Fibroblast growth factor receptor inhibition for the treatment of disease
HRP20251099T1 (hr) * 2014-06-09 2025-11-07 Ultragenyx Pharmaceutical Inc. Učinkovita i djelotvorna kontrola serumskog fosfata za optimalno stvaranje kostiju
WO2018069232A1 (en) 2016-10-10 2018-04-19 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for predicting the risk of having cardiac hypertrophy
EP3604517A4 (en) 2017-03-30 2020-12-16 Sysmex Corporation ANTI-APOA1 ANTIBODIES
JP2022527790A (ja) * 2019-03-29 2022-06-06 アターガ，エルエルシー 抗ｆｇｆ２３抗体分子
EP4570910A1 (en) 2022-08-10 2025-06-18 Kyowa Kirin Co., Ltd. Anti-fgf23 antibody, and fragment of said antibody
KR20250157441A (ko) * 2023-03-10 2025-11-04 울트라제닉스 파마수티컬 인코포레이티드 개선된 친화도 및 효능을 갖는 인간 fgf23-결합 항체
CN119080938B (zh) * 2023-06-05 2025-06-24 东莞市朋志生物科技有限公司 抗25羟维生素d抗体、检测25羟维生素d的试剂和试剂盒
CN119954951A (zh) * 2024-12-31 2025-05-09 上海良润生物医药科技有限公司 iFGF23特异性抗体及其在制备慢性肾病辅助诊断试剂中的应用

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EP1310554B1 (en) 2000-08-11 2010-05-26 Kyowa Hakko Kirin Co., Ltd. Polypeptides controlling phosphoric acid metabolism, calcium metabolism, calcification and vitamin d metabolism and dnas encoding the same
JP3523245B1 (ja) 2000-11-30 2004-04-26 メダレックス，インコーポレーテッド ヒト抗体作製用トランスジェニック染色体導入齧歯動物
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US7883705B2 (en) * 2007-02-14 2011-02-08 Kyowa Hakko Kirin Co., Ltd. Anti FGF23 antibody and a pharmaceutical composition comprising the same

Also Published As

Publication number Publication date
PT2502996T (pt) 2017-05-10
HUE031728T2 (en) 2017-07-28
EP2502996A2 (en) 2012-09-26
EP2128253A4 (en) 2010-03-10
FR18C1032I1 (lt) 2018-08-31
DK3181691T3 (da) 2020-08-17
LT2502996T (lt) 2017-06-26
PL3181691T3 (pl) 2020-11-02
TW200902549A (en) 2009-01-16
HK1172917A1 (en) 2013-05-03
SI3181691T1 (sl) 2020-09-30
PT3181691T (pt) 2020-08-26
SI2502996T1 (sl) 2017-08-31
JPWO2008099969A1 (ja) 2010-05-27
KR20090114452A (ko) 2009-11-03
CY2018021I2 (el) 2019-07-10
WO2008099969A1 (ja) 2008-08-21
CY1118835T1 (el) 2018-01-10
US20090148461A1 (en) 2009-06-11
CN101652476A (zh) 2010-02-17
AU2008215346B2 (en) 2013-01-10
NL300945I2 (en) 2020-05-13
NL300945I1 (en) 2018-08-15
EP2502996A3 (en) 2013-04-10
EP3181691B1 (en) 2020-07-15
KR101462291B1 (ko) 2014-11-14
FR18C1032I2 (fr) 2019-08-09
US9290569B2 (en) 2016-03-22
EP2128253A1 (en) 2009-12-02
EP3181691A1 (en) 2017-06-21
LT3181691T (lt) 2020-08-25
LUC00081I2 (lt) 2018-10-01
ES2625823T3 (es) 2017-07-20
LTPA2018508I1 (lt) 2018-09-10
CA2677782C (en) 2016-07-26
PL2502996T3 (pl) 2017-07-31
CY1123240T1 (el) 2021-10-29
HRP20170548T1 (hr) 2017-08-25
ES2811318T3 (es) 2021-03-11
EP2128253B1 (en) 2014-12-03
PT2128253E (pt) 2015-02-04
CY2018021I1 (el) 2019-07-10
HUE050517T2 (hu) 2020-12-28
US10202446B2 (en) 2019-02-12
CN101652476B (zh) 2012-07-04
JP4800396B2 (ja) 2011-10-26
LUC00082I2 (lt) 2018-10-01
ES2530670T3 (es) 2015-03-04
NO2018025I1 (no) 2018-08-09
PL2128253T3 (pl) 2015-04-30
CN102702355B (zh) 2014-09-24
HK1140228A1 (en) 2010-10-08
AU2008215346A1 (en) 2008-08-21
CA2677782A1 (en) 2008-08-21
DK2128253T3 (en) 2015-01-05
US20160159895A1 (en) 2016-06-09
HUS1800034I1 (hu) 2018-09-28
DK2502996T3 (en) 2017-05-08
US7883705B2 (en) 2011-02-08
EP2502996B1 (en) 2017-03-29
CN102702355A (zh) 2012-10-03
US20190106485A1 (en) 2019-04-11
TWI422593B (zh) 2014-01-11
HRP20201266T1 (hr) 2021-02-05
US20110182913A1 (en) 2011-07-28

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