LU67815A1 - - Google Patents

Info

Publication number
LU67815A1
LU67815A1 LU67815A LU67815DA LU67815A1 LU 67815 A1 LU67815 A1 LU 67815A1 LU 67815 A LU67815 A LU 67815A LU 67815D A LU67815D A LU 67815DA LU 67815 A1 LU67815 A1 LU 67815A1
Authority
LU
Luxembourg
Application number
LU67815A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of LU67815A1 publication Critical patent/LU67815A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02—Seven-membered rings
    • C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/14—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/22—Eight-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/18—Eight-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
LU67815A 1972-06-19 1973-06-19 LU67815A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26376672A 1972-06-19 1972-06-19
US357528A US3914421A (en) 1972-06-19 1973-05-07 Pyridopyrrolobenzheterocycles for combatting depression

Publications (1)

Publication Number Publication Date
LU67815A1 true LU67815A1 (fr) 1973-09-26

Family

ID=26950035

Family Applications (1)

Application Number Title Priority Date Filing Date
LU67815A LU67815A1 (fr) 1972-06-19 1973-06-19

Country Status (7)

Country Link
US (1) US3914421A (fr)
BE (1) BE801108A (fr)
DE (1) DE2330719A1 (fr)
FR (1) FR2189048B1 (fr)
IL (1) IL42430A0 (fr)
LU (1) LU67815A1 (fr)
NL (1) NL7308525A (fr)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115577A (en) * 1972-06-19 1978-09-19 Endo Laboratories, Inc. Pyridopyrrolobenzheterocycles
US4013652A (en) * 1972-06-19 1977-03-22 Endo Laboratories, Inc. Pyridopyrrolobenzoxazine
US4183936A (en) * 1972-06-19 1980-01-15 Endo Laboratories, Inc. Pyridopyrrolobenzheterocycles
ES481298A1 (es) * 1978-06-05 1980-08-16 Sankyo Co Un procedimiento para preparar nuevos benzotiazo-derivados.
US4219550A (en) * 1978-11-09 1980-08-26 E. I. Du Pont De Nemours And Company Cis- and trans- octahydropyridopyrrolobenzheterocycles
EP0357417A1 (fr) * 1988-09-01 1990-03-07 Glaxo Group Limited Dérivés de lactames
US5223625A (en) * 1988-12-22 1993-06-29 Duphar International Research B.V. Annelated indolo [3,2,-C]lactams
EP0380155A1 (fr) * 1989-01-19 1990-08-01 Duphar International Research B.V Dérivés de 1,2,3,4-tétrahydro-bêta-carboline, 8,9-annelés
MXPA01012914A (es) 1999-06-15 2004-04-21 Bristol Myers Squibb Co Gama-carbolinas fundidas de heterociclo substituido.
US7071186B2 (en) * 1999-06-15 2006-07-04 Bristol-Myers Squibb Pharma Co. Substituted heterocycle fused gamma-carbolines
US6713471B1 (en) 1999-06-15 2004-03-30 Bristol-Myers Squibb Pharma Company Substituted heterocycle fused gamma-carbolines
EP1399445B9 (fr) 2000-12-20 2010-07-21 Bristol-Myers Squibb Company Pyrroloquinoleines et pyridoquinoleines substituees comme agonistes et antagonistes de la serotonine
MXPA03005438A (es) * 2000-12-20 2004-05-05 Bristol Myers Squibb Co Pirioindoles substituidos como agonistas y antagonistas de serotonina.
US6849619B2 (en) * 2000-12-20 2005-02-01 Bristol-Myers Squibb Company Substituted pyridoindoles as serotonin agonists and antagonists
BR0116347A (pt) 2000-12-20 2004-07-06 Bristol Myers Squibb Pharma Co Derivados pirazinoquinoxalina substituìdos como agonistas e antagonistas do receptor de serotonina
US6887868B2 (en) 2001-09-21 2005-05-03 Pharmacia & Upjohn Company Therapeutic 5-HT ligand compounds
AU2003303210A1 (en) * 2002-12-19 2004-07-14 Bristol-Myers Squibb Company Substituted tricyclic gamma-carbolines as serotonin receptor agonists and antagonists
CN101796051B (zh) * 2007-03-12 2013-11-06 细胞内治疗公司 与取代的杂环稠合的γ-咔啉的合成
US8575186B2 (en) 2009-10-05 2013-11-05 Albany Molecular Research, Inc. Epiminocycloalkyl[b] indole derivatives as serotonin sub-type 6 (5-HT6) modulators and uses thereof
CA2823955A1 (fr) 2011-01-19 2012-07-26 Albany Molecular Research, Inc. Benzofuro[3,2-c]pyridines et analogues associes en tant que modulateurs du sous-type 6 de la serotonine (5-ht6) pour traitement de l'obesite, du syndrome metabolique, de la cognition et de la schizophrenie
EP2836211B1 (fr) 2012-04-14 2019-03-20 Intra-Cellular Therapies, Inc. Traitement du PTSD et du trouble des impulsions
PT2968320T (pt) 2013-03-15 2021-01-28 Intra Cellular Therapies Inc Compostos orgânicos
IL321987A (en) * 2013-12-03 2025-09-01 Intra Cellular Therapies Inc A long-acting injectable preparation containing polymeric microspheres of modified compressed gamma-carboline heterocyclic compounds or a sustained-release pharmaceutical preparation containing these compounds for use in the treatment of bipolar I and/or bipolar II disorders
CN106456638A (zh) 2014-04-04 2017-02-22 细胞内治疗公司 有机化合物
WO2015154025A1 (fr) 2014-04-04 2015-10-08 Intra-Cellular Therapies, Inc. Composés organiques
CA3011983A1 (fr) 2016-01-26 2017-08-03 Intra-Cellular Therapies, Inc. Gamma-carbolines fusionnees a heterocycles substituees
EP3407889B1 (fr) 2016-03-25 2021-05-19 Intra-Cellular Therapies, Inc. Composés organiques et leur utilisation dans le traitement ou la prévention de maladies du système nerveux central
US10682354B2 (en) 2016-03-28 2020-06-16 Intra-Cellular Therapies, Inc. Compositions and methods
JP2019513143A (ja) 2016-03-28 2019-05-23 イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−Ｃｅｌｌｕｌａｒ Ｔｈｅｒａｐｉｅｓ， Ｉｎｃ． 新規塩類および結晶
JP6997718B2 (ja) 2016-03-28 2022-01-18 イントラ－セルラー・セラピーズ・インコーポレイテッド 新規共結晶
US11331316B2 (en) 2016-10-12 2022-05-17 Intra-Cellular Therapies, Inc. Amorphous solid dispersions
WO2018126140A1 (fr) 2016-12-29 2018-07-05 Intra-Cellular Therapies, Inc. Composés organiques
WO2018126143A1 (fr) 2016-12-29 2018-07-05 Intra-Cellular Therapies, Inc. Composés organiques
WO2018175969A1 (fr) 2017-03-24 2018-09-27 Intra-Cellular Therapies, Inc. Nouvelles compositions et méthodes
IL272252B2 (en) 2017-07-26 2024-03-01 Intra Cellular Therapies Inc Derivatives of substituted heterocycle fused gamma-carbolines, pharmaceutical compositions comnprising them and their use in treatment
KR102899502B1 (ko) 2017-07-26 2025-12-11 인트라-셀룰라 써래피스, 인코퍼레이티드. 유기 화합물
MX2020009928A (es) 2018-03-23 2021-01-08 Intra Cellular Therapies Inc Compuestos organicos.
EP3628007B1 (fr) 2018-06-06 2023-05-03 Intra-Cellular Therapies, Inc. Nouveaux sels et cristaux
WO2019237037A1 (fr) 2018-06-08 2019-12-12 Intra-Cellular Therapies, Inc. Nouvelles méthodes
EP3609891B1 (fr) 2018-06-11 2026-02-11 Intra-Cellular Therapies, Inc. Synthèse de gamma-carbolines fusionnées à hétérocycles substitués
WO2020047241A1 (fr) 2018-08-29 2020-03-05 Intra-Cellular Therapies, Inc. Nouvelles compositions et méthodes
KR20210052472A (ko) 2018-08-31 2021-05-10 인트라-셀룰라 써래피스, 인코퍼레이티드. 신규한 방법
WO2020047407A1 (fr) 2018-08-31 2020-03-05 Intra-Cellular Therapies, Inc. Nouvelles méthodes
BR112022000231A2 (pt) 2019-07-07 2022-02-22 Intra Cellular Therapies Inc Novos métodos
US12414948B2 (en) 2022-05-18 2025-09-16 Intra-Cellular Therapies, Inc. Methods

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH307223A (de) * 1952-04-28 1955-05-15 Bayer Ag Verfahren zur Herstellung eines Derivates des Tetrahydro-y-carbolins.

Also Published As

Publication number Publication date
BE801108A (fr) 1973-10-15
IL42430A0 (en) 1973-08-29
NL7308525A (fr) 1973-12-21
FR2189048A1 (fr) 1974-01-25
DE2330719A1 (de) 1974-01-10
FR2189048B1 (fr) 1976-10-22
US3914421A (en) 1975-10-21

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