LU83343A1 - Procede d'obtention de preparations de toxoplasmes pour le diagnostic de la toxoplasmose,et preparations ainsi obtenues - Google Patents

Procede d'obtention de preparations de toxoplasmes pour le diagnostic de la toxoplasmose,et preparations ainsi obtenues Download PDF

Info

Publication number: LU83343A1
Authority: LU; Luxembourg
Prior art keywords: cells; mice; toxoplasmas; inoculated; infected
Prior art date: 1980-05-20

Application number

LU83343A

Other languages

English (en)

French (fr)

Inventor

G Trouyez

Original Assignee

Biomerieux Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-05-20

Filing date

1981-05-06

Publication date

1982-01-20

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9242172&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU83343(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1981-05-06 Application filed by Biomerieux Sa filed Critical Biomerieux Sa

1982-01-20 Publication of LU83343A1 publication Critical patent/LU83343A1/fr

Links

238000000034 method Methods 0.000 title claims abstract description 28
238000002360 preparation method Methods 0.000 title claims abstract description 13
238000003745 diagnosis Methods 0.000 title abstract description 5
201000005485 Toxoplasmosis Diseases 0.000 title abstract description 4
241000223996 Toxoplasma Species 0.000 claims abstract description 27
241000699670 Mus sp. Species 0.000 claims abstract description 25
230000004520 agglutination Effects 0.000 claims abstract description 14
239000000203 mixture Substances 0.000 claims abstract description 12
238000011081 inoculation Methods 0.000 claims abstract description 7
239000000427 antigen Substances 0.000 claims description 16
102000036639 antigens Human genes 0.000 claims description 16
108091007433 antigens Proteins 0.000 claims description 16
210000000416 exudates and transudate Anatomy 0.000 claims description 14
WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 claims description 10
208000015181 infectious disease Diseases 0.000 claims description 8
239000000725 suspension Substances 0.000 claims description 8
DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 claims description 8
239000013049 sediment Substances 0.000 claims description 7
241000699666 Mus <mouse, genus> Species 0.000 claims description 5
102000004142 Trypsin Human genes 0.000 claims description 5
108090000631 Trypsin Proteins 0.000 claims description 5
239000012588 trypsin Substances 0.000 claims description 5
206010003445 Ascites Diseases 0.000 claims description 4
238000005119 centrifugation Methods 0.000 claims description 4
206010039491 Sarcoma Diseases 0.000 claims description 3
239000000872 buffer Substances 0.000 claims description 3
239000003755 preservative agent Substances 0.000 claims description 2
230000002335 preservative effect Effects 0.000 claims description 2
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 2
239000007788 liquid Substances 0.000 claims 3
210000002966 serum Anatomy 0.000 claims 2
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 1
238000004519 manufacturing process Methods 0.000 claims 1
238000004062 sedimentation Methods 0.000 claims 1
244000045947 parasite Species 0.000 description 16
238000012360 testing method Methods 0.000 description 15
238000010790 dilution Methods 0.000 description 6
239000012895 dilution Substances 0.000 description 6
239000002953 phosphate buffered saline Substances 0.000 description 5
238000012546 transfer Methods 0.000 description 5
230000009089 cytolysis Effects 0.000 description 4
230000035945 sensitivity Effects 0.000 description 4
239000000243 solution Substances 0.000 description 4
238000010166 immunofluorescence Methods 0.000 description 3
230000009172 bursting Effects 0.000 description 2
241000894006 Bacteria Species 0.000 description 1
102000004190 Enzymes Human genes 0.000 description 1
108090000790 Enzymes Proteins 0.000 description 1
230000001154 acute effect Effects 0.000 description 1
238000007796 conventional method Methods 0.000 description 1
LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 1
238000001914 filtration Methods 0.000 description 1
239000012530 fluid Substances 0.000 description 1
239000008098 formaldehyde solution Substances 0.000 description 1
230000035931 haemagglutination Effects 0.000 description 1
238000003306 harvesting Methods 0.000 description 1
238000002347 injection Methods 0.000 description 1
239000007924 injection Substances 0.000 description 1
230000003834 intracellular effect Effects 0.000 description 1
238000007912 intraperitoneal administration Methods 0.000 description 1
239000000463 material Substances 0.000 description 1
238000011160 research Methods 0.000 description 1
238000009589 serological test Methods 0.000 description 1
238000010186 staining Methods 0.000 description 1
238000004448 titration Methods 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/002—Protozoa antigens
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56905—Protozoa
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/947—Microorganisms using protozoa
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/961—Chemistry: molecular biology and microbiology including a step of forming, releasing, or exposing the antigen or forming the hapten-immunogenic carrier complex or the antigen per se
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/811—Test for named disease, body condition or organ function
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/822—Protozoa

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Tropical Medicine & Parasitology (AREA)
Hematology (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Urology & Nephrology (AREA)
Food Science & Technology (AREA)
Mycology (AREA)
Biotechnology (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
Virology (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Cell Biology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Medicinal Preparation (AREA)

LU83343A 1980-05-20 1981-05-06 Procede d'obtention de preparations de toxoplasmes pour le diagnostic de la toxoplasmose,et preparations ainsi obtenues LU83343A1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR8011261		1980-05-20
FR8011261A FR2482980A1 (fr)	1980-05-20	1980-05-20	Procede d'obtention de preparations de toxoplasmes pour le diagnostic de la toxoplasmose, et preparations ainsi obtenues

Publications (1)

Publication Number	Publication Date
LU83343A1 true LU83343A1 (fr)	1982-01-20

Family

ID=9242172

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LU83343A LU83343A1 (fr)	1980-05-20	1981-05-06	Procede d'obtention de preparations de toxoplasmes pour le diagnostic de la toxoplasmose,et preparations ainsi obtenues

Country Status (9)

Country	Link
US (1)	US4480043A (de)
EP (1)	EP0040572B1 (de)
JP (1)	JPS5739350A (de)
AT (1)	ATE4282T1 (de)
BE (1)	BE888855A (de)
DE (1)	DE3160694D1 (de)
FR (1)	FR2482980A1 (de)
IT (1)	IT1148013B (de)
LU (1)	LU83343A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2518407A1 (fr) *	1981-12-17	1983-06-24	Merieux Inst	Nouvel antigene pour la recherche de l'immunite toxoplasmique et son procede de preparation
BR8805647A (pt)	1987-02-27	1989-10-31	Gist Brocades Nv	Processo para clonagem molecular e expressao de genes que codificam para enzimas proteoliticas
GB8717863D0 (en) *	1987-07-28	1987-09-03	Acade Diagnostic Systems Sa Nv	Determination of antibodies
US4824666A (en) *	1987-11-13	1989-04-25	The United States Of America As Represented By The Secretary Of The Army	Method of large scale growth of toxoplasmic microorganisms
US4877726A (en) *	1988-03-02	1989-10-31	Research Institute Of Palo Alto Medical Foundation	Method for the detection of acute-phase toxoplasma infection
DE4302012C1 (de) *	1993-01-26	1994-07-21	Serosearch Gmbh Entwicklung Un	Immunologischer Test
JP2009122128A (ja) *	2009-03-12	2009-06-04	Shimadzu Corp	移動相液体容器

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2226468A1 (en) *	1973-04-18	1974-11-15	Merieux Bd	Toxoplasma antigens - as agents for detecting toxoplasmosis by direct agglutination

1980
- 1980-05-20 FR FR8011261A patent/FR2482980A1/fr active Granted
1981
- 1981-05-06 LU LU83343A patent/LU83343A1/fr unknown
- 1981-05-12 US US06/262,893 patent/US4480043A/en not_active Expired - Lifetime
- 1981-05-18 JP JP56073634A patent/JPS5739350A/ja active Granted
- 1981-05-18 IT IT48488/81A patent/IT1148013B/it active
- 1981-05-19 BE BE0/204224A patent/BE888855A/fr not_active IP Right Cessation
- 1981-05-19 DE DE8181400782T patent/DE3160694D1/de not_active Expired
- 1981-05-19 AT AT81400782T patent/ATE4282T1/de active
- 1981-05-19 EP EP81400782A patent/EP0040572B1/de not_active Expired

Also Published As

Publication number	Publication date
IT1148013B (it)	1986-11-26
ATE4282T1 (de)	1983-08-15
US4480043A (en)	1984-10-30
FR2482980B1 (de)	1984-03-16
EP0040572B1 (de)	1983-07-27
JPH0136066B2 (de)	1989-07-28
DE3160694D1 (en)	1983-09-01
BE888855A (fr)	1981-11-19
FR2482980A1 (fr)	1981-11-27
JPS5739350A (en)	1982-03-04
EP0040572A1 (de)	1981-11-25
IT8148488A0 (it)	1981-05-18

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Legal Events

Date	Code	Title	Description
1981-05-06	DT	Application date
1991-05-23	TA	Annual fee