LU90846I2 - Starlix-nateglinide et ses d-riv-s pharmaceutiquement acceptables - Google Patents

Starlix-nateglinide et ses d-riv-s pharmaceutiquement acceptables

Info

Publication number
LU90846I2
LU90846I2 LU90846C LU90846C LU90846I2 LU 90846 I2 LU90846 I2 LU 90846I2 LU 90846 C LU90846 C LU 90846C LU 90846 C LU90846 C LU 90846C LU 90846 I2 LU90846 I2 LU 90846I2
Authority
LU
Luxembourg
Prior art keywords
crystals
solvent
compound
starlix
nateglinide
Prior art date
Application number
LU90846C
Other languages
English (en)
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27169694&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU90846(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Publication of LU90846I2 publication Critical patent/LU90846I2/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/22—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C233/63—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
LU90846C 1991-07-30 2001-10-03 Starlix-nateglinide et ses d-riv-s pharmaceutiquement acceptables LU90846I2 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP18969691 1991-07-30
JP19945391 1991-08-08
CA002114678A CA2114678C (fr) 1991-07-30 1994-02-01 Cristaux de n-(trans-4-isopropylcyclohexylcarbonyl)- d-phenylalanine et methodes pour les preparer

Publications (1)

Publication Number Publication Date
LU90846I2 true LU90846I2 (fr) 2002-02-04

Family

ID=27169694

Family Applications (2)

Application Number Title Priority Date Filing Date
LU90843C LU90843I2 (fr) 1991-07-30 2001-09-28 Starlix-nateglinide et ses d-riv-s pharmaceutiquement acceptables
LU90846C LU90846I2 (fr) 1991-07-30 2001-10-03 Starlix-nateglinide et ses d-riv-s pharmaceutiquement acceptables

Family Applications Before (1)

Application Number Title Priority Date Filing Date
LU90843C LU90843I2 (fr) 1991-07-30 2001-09-28 Starlix-nateglinide et ses d-riv-s pharmaceutiquement acceptables

Country Status (11)

Country Link
US (1) US5488150A (fr)
EP (1) EP0526171B1 (fr)
JP (1) JP2508949B2 (fr)
AT (1) ATE149483T1 (fr)
BR (1) BR1100807A (fr)
CA (1) CA2114678C (fr)
DE (2) DE10199058I2 (fr)
DK (1) DK0526171T3 (fr)
ES (1) ES2100291T3 (fr)
LU (2) LU90843I2 (fr)
NL (1) NL300063I2 (fr)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE503472T1 (de) 1996-11-15 2011-04-15 Ajinomoto Kk Nateglinide-tablettenzubereitungen
GB9713730D0 (en) 1997-06-30 1997-09-03 Ciba Geigy Ag Organic compounds
CO5200844A1 (es) 1999-09-17 2002-09-27 Novartis Ag Una combinacion que comprende nateglinida y cuando por menos otro compuesto antidiabetico usada para el tratamiento de desordenes metabolicos, especialmente diabetes, o de una enfermedad o condicion asociada con dibetes
US6559188B1 (en) 1999-09-17 2003-05-06 Novartis Ag Method of treating metabolic disorders especially diabetes, or a disease or condition associated with diabetes
US6878749B2 (en) * 1999-09-17 2005-04-12 Novartis Ag Method of treating metabolic disorders, especially diabetes, or a disease or condition associated with diabetes
EP1743655B1 (fr) 2000-01-21 2014-06-25 Novartis AG Combinaisons à base d'inhibiteurs de DPP-IV et d'antidiabetiques
PE20020617A1 (es) 2000-08-22 2002-08-05 Novartis Ag Composicion que comprende un antagonista del receptor at1 y un potenciador de la secrecion de insulina o un sensibilizante a la insulina
ATE368641T1 (de) 2000-10-18 2007-08-15 Ajinomoto Kk Verfahren zur herstellung von nateglinidin- kristallen
CN1273442C (zh) * 2000-10-18 2006-09-06 味之素株式会社 酰基苯丙氨酸的制备方法
AU2001296000A1 (en) * 2000-10-24 2002-05-27 Ajinomoto Co., Inc. Nateglinide-containing hydrophilic drug preparations
MXPA03003685A (es) * 2000-10-24 2004-01-26 Ajinomoto Kk Preparaciones que contienen nateglinida.
RU2275354C2 (ru) * 2000-10-24 2006-04-27 Адзиномото Ко., Инк. Способы получения кристаллов в-типа натеглинида
AR035425A1 (es) * 2001-01-30 2004-05-26 Teijin Ltd Cristal de diclorhidrato del acido 3-(3-amidinofenil)-5-[({[1-(iminoetil)-4-piperidil]metil}amino)metil]benzoico y proceso para prepararlo
WO2003022251A1 (fr) * 2001-09-12 2003-03-20 Alembic Limited Nouvelle forme de cristal stable de n-(trans-4-isopropylcyclohexyl carbonyl)-d-phenylalanine et procede de preparation correspondant
CA2478599A1 (fr) * 2002-03-11 2003-09-18 Novartis Ag Sels de nateglinide
US7411089B2 (en) 2002-04-15 2008-08-12 Ajinomoto Co., Inc. Nateglinide crystals
JP4538842B2 (ja) * 2002-04-15 2010-09-08 味の素株式会社 新規ナテグリニド結晶
US7247746B2 (en) * 2002-04-15 2007-07-24 Novartis, Ag Crystal forms of N-(trans-4-isopropylcyclohexylcarbonyl)-D-phenylalanine
SK287644B6 (sk) * 2002-04-29 2011-05-06 Biocon Limited Kryštalický N-(trans)-4-izopropylcyklohexylkarbonyl)-D- fenylalanín vo forme C a spôsob jeho prípravy
RU2324676C2 (ru) * 2002-04-29 2008-05-20 Байокон Лимитид Кристаллический n-(транс-4-изопропилциклогексилкарбонил)-d-фенилаланин формы с для лечения сахарного диабета типа 2 и способ его получения
AU2003256454A1 (en) * 2002-07-03 2004-01-23 Teva Pharmaceutical Industries Ltd. Process for preparing nateglinide and intermediates thereof
US6861553B2 (en) * 2002-07-03 2005-03-01 Teva Pharmaceuticals Industries Ltd. Process for preparing nateglinide and intermediates thereof
US7534913B2 (en) * 2002-07-18 2009-05-19 Teva Pharmaceutica Industries Ltd. Crystalline form of nateglinide
US7148376B2 (en) * 2002-07-18 2006-12-12 Teva Pharmaceutical Industries Ltd. Polymorphic forms of nateglinide
US7420084B2 (en) * 2002-07-18 2008-09-02 Teva Pharmaceutical Industries Ltd. Polymorphic forms of nateglinide
US20050075400A1 (en) * 2002-07-18 2005-04-07 Ronit Yahalomi Polymorphic forms of nateglinide
US7358390B2 (en) * 2002-07-18 2008-04-15 Teva Pharmaceutical Industries Ltd. Polymorphic forms of nateglinide
WO2004020396A1 (fr) * 2002-08-28 2004-03-11 Dr. Reddy's Laboratories Limited Forme cristalline de nateglinide et procede de preparation correspondant
US7449519B2 (en) * 2003-02-18 2008-11-11 Konishi Co., Ltd. Curing resin, method for producing same and curing resin composition
HU227073B1 (hu) * 2003-07-10 2010-06-28 Richter Gedeon Nyrt Eljárás királisan tiszta N-(transz-4-izopropil-ciklohexilkarbonil)-D-fenil-alanin (nateglinid) és kristálymódosulatainak elõállítására, valamint a G-kristálymódosulata
US20060004102A1 (en) * 2004-05-07 2006-01-05 Shlomit Wizel Polymorphic forms of nateglinide
US7425648B2 (en) 2005-01-03 2008-09-16 A.M.S.A. Anonima Materie Sintetiche E. Affini S.P.A. Process for the preparation of nateglinide, preferably in B-form
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
PT1931350E (pt) 2005-09-14 2014-02-12 Takeda Pharmaceutical Administração de inibidores de dipeptidil peptidase
CN101415668B (zh) * 2006-03-31 2013-06-19 味之素株式会社 羧酸酰氯化合物的制造方法
CN103951583B (zh) * 2006-12-06 2016-01-06 科内图斯医药公司 一种抑制剂的结晶形式
NZ596302A (en) 2009-05-15 2014-01-31 Novartis Ag Aryl pyridine as aldosterone synthase inhibitors
JP5466759B2 (ja) 2009-05-28 2014-04-09 ノバルティス アーゲー ネプリライシン阻害剤としての置換アミノ酪酸誘導体
SG176009A1 (en) 2009-05-28 2011-12-29 Novartis Ag Substituted aminopropionic derivatives as neprilysin inhibitors
WO2011041293A1 (fr) 2009-09-30 2011-04-07 Takeda Pharmaceutical Company Limited Dérivés pyrazolo [1, 5—a] pyrimidines comme inhibiteurs de kinase 1 régulatrice de signal d'apoptose
US8519134B2 (en) 2009-11-17 2013-08-27 Novartis Ag Aryl-pyridine derivatives as aldosterone synthase inhibitors
JO2967B1 (en) 2009-11-20 2016-03-15 نوفارتس ايه جي Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors
ES2472446T3 (es) 2009-11-30 2014-07-01 Novartis Ag Derivados de imidazol como inhibidores de aldosterona sintasa
PL2531501T3 (pl) 2010-02-03 2014-05-30 Takeda Pharmaceuticals Co Inhibitory kinazy 1 regulującej sygnał apoptotyczny
US8673974B2 (en) 2010-11-16 2014-03-18 Novartis Ag Substituted amino bisphenyl pentanoic acid derivatives as NEP inhibitors
US8877815B2 (en) 2010-11-16 2014-11-04 Novartis Ag Substituted carbamoylcycloalkyl acetic acid derivatives as NEP
UY35144A (es) 2012-11-20 2014-06-30 Novartis Ag Miméticos lineales sintéticos de apelina para el tratamiento de insuficiencia cardiaca
TR201808541T4 (tr) 2013-02-14 2018-07-23 Novartis Ag Nep (nötr endopeptidaz) inhibitörleri olarak ikame edilmiş bisfenil butanoik fosfonik asit türevleri.
HK1218252A1 (zh) 2013-07-25 2017-02-10 Novartis Ag 合成apelin多肽之生物结合物
KR20160031551A (ko) 2013-07-25 2016-03-22 노파르티스 아게 심부전의 치료를 위한 시클릭 폴리펩티드
MA41580A (fr) 2015-01-23 2017-11-29 Novartis Ag Conjugués d'acides gras de l'apeline synthétique présentant une demi-vie améliorée
UY38072A (es) 2018-02-07 2019-10-01 Novartis Ag Compuestos derivados de éster butanoico sustituido con bisfenilo como inhibidores de nep, composiciones y combinaciones de los mismos
CN109369443A (zh) * 2018-11-05 2019-02-22 扬子江药业集团江苏海慈生物药业有限公司 一种新的那格列奈h晶型的制备方法

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US196222A (en) * 1877-10-16 Improvement in belt-tighteners
JPS6354321A (ja) * 1985-03-27 1988-03-08 Ajinomoto Co Inc 血糖降下剤

Also Published As

Publication number Publication date
JPH05208943A (ja) 1993-08-20
US5488150A (en) 1996-01-30
EP0526171A3 (en) 1993-05-05
NL300063I2 (nl) 2002-02-01
DK0526171T3 (da) 1997-08-25
EP0526171B1 (fr) 1997-03-05
CA2114678C (fr) 1999-04-27
EP0526171A2 (fr) 1993-02-03
DE69217762D1 (de) 1997-04-10
DE69217762T2 (de) 1997-10-09
DE10199058I2 (de) 2006-04-27
DE10199058I1 (de) 2002-01-24
ATE149483T1 (de) 1997-03-15
CA2114678A1 (fr) 1995-08-02
LU90843I2 (fr) 2002-02-04
NL300063I1 (nl) 2001-12-01
ES2100291T3 (es) 1997-06-16
BR1100807A (pt) 1999-12-28
JP2508949B2 (ja) 1996-06-19

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