LU90846I2 - Starlix-nateglinide et ses d-riv-s pharmaceutiquement acceptables - Google Patents

Starlix-nateglinide et ses d-riv-s pharmaceutiquement acceptables

Info

Publication number
LU90846I2
LU90846I2 LU90846C LU90846C LU90846I2 LU 90846 I2 LU90846 I2 LU 90846I2 LU 90846 C LU90846 C LU 90846C LU 90846 C LU90846 C LU 90846C LU 90846 I2 LU90846 I2 LU 90846I2
Authority
LU
Luxembourg
Prior art keywords
crystals
solvent
compound
starlix
nateglinide
Prior art date
Application number
LU90846C
Other languages
English (en)
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27169694&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU90846(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Publication of LU90846I2 publication Critical patent/LU90846I2/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/22—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C233/63—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
LU90846C 1991-07-30 2001-10-03 Starlix-nateglinide et ses d-riv-s pharmaceutiquement acceptables LU90846I2 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP18969691 1991-07-30
JP19945391 1991-08-08
CA002114678A CA2114678C (fr) 1991-07-30 1994-02-01 Cristaux de n-(trans-4-isopropylcyclohexylcarbonyl)- d-phenylalanine et methodes pour les preparer

Publications (1)

Publication Number Publication Date
LU90846I2 true LU90846I2 (fr) 2002-02-04

Family

ID=27169694

Family Applications (2)

Application Number Title Priority Date Filing Date
LU90843C LU90843I2 (fr) 1991-07-30 2001-09-28 Starlix-nateglinide et ses d-riv-s pharmaceutiquement acceptables
LU90846C LU90846I2 (fr) 1991-07-30 2001-10-03 Starlix-nateglinide et ses d-riv-s pharmaceutiquement acceptables

Family Applications Before (1)

Application Number Title Priority Date Filing Date
LU90843C LU90843I2 (fr) 1991-07-30 2001-09-28 Starlix-nateglinide et ses d-riv-s pharmaceutiquement acceptables

Country Status (11)

Country Link
US (1) US5488150A (fr)
EP (1) EP0526171B1 (fr)
JP (1) JP2508949B2 (fr)
AT (1) ATE149483T1 (fr)
BR (1) BR1100807A (fr)
CA (1) CA2114678C (fr)
DE (2) DE69217762T2 (fr)
DK (1) DK0526171T3 (fr)
ES (1) ES2100291T3 (fr)
LU (2) LU90843I2 (fr)
NL (1) NL300063I2 (fr)

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KR100343062B1 (ko) 1996-11-15 2002-07-02 에가시라 구니오 정제 조성물
GB9713730D0 (en) 1997-06-30 1997-09-03 Ciba Geigy Ag Organic compounds
CO5200844A1 (es) 1999-09-17 2002-09-27 Novartis Ag Una combinacion que comprende nateglinida y cuando por menos otro compuesto antidiabetico usada para el tratamiento de desordenes metabolicos, especialmente diabetes, o de una enfermedad o condicion asociada con dibetes
US6559188B1 (en) 1999-09-17 2003-05-06 Novartis Ag Method of treating metabolic disorders especially diabetes, or a disease or condition associated with diabetes
US6878749B2 (en) * 1999-09-17 2005-04-12 Novartis Ag Method of treating metabolic disorders, especially diabetes, or a disease or condition associated with diabetes
EP1741445B1 (fr) 2000-01-21 2013-08-14 Novartis AG Combinaisons à base d'inhibiteurs de DPP-IV et d'antidiabetiques
AR033390A1 (es) 2000-08-22 2003-12-17 Novartis Ag Una composicion farmaceutica que comprende un antagonista del receptor at1 y un potenciador de la secrecion de insulina, el uso de dicha composicion para la fabricacion de un medicamento y un kit de partes
ATE373635T1 (de) * 2000-10-18 2007-10-15 Ajinomoto Kk Verfahren zur herstellung von acylphenylalaninen
WO2002032854A1 (fr) * 2000-10-18 2002-04-25 Ajinomoto Co.,Inc. Procede de production de cristaux de nateglinide
BR0114846A (pt) * 2000-10-24 2004-02-25 Ajinomoto Kk Método para produzir cristais de tipo b de nateglinida substancialmente livres de cristais de tipo h
AU2001295999A1 (en) * 2000-10-24 2002-05-06 Ajinomoto Co., Inc. Nateglinide-containing preparations
PT1334721E (pt) * 2000-10-24 2009-06-01 Ajinomoto Kk Preparações de fármacos hidrofílicos contendo nateglinida
AR035425A1 (es) * 2001-01-30 2004-05-26 Teijin Ltd Cristal de diclorhidrato del acido 3-(3-amidinofenil)-5-[({[1-(iminoetil)-4-piperidil]metil}amino)metil]benzoico y proceso para prepararlo
WO2003022251A1 (fr) * 2001-09-12 2003-03-20 Alembic Limited Nouvelle forme de cristal stable de n-(trans-4-isopropylcyclohexyl carbonyl)-d-phenylalanine et procede de preparation correspondant
CN1274668C (zh) * 2002-03-11 2006-09-13 诺瓦提斯公司 那格列奈的盐
US7411089B2 (en) 2002-04-15 2008-08-12 Ajinomoto Co., Inc. Nateglinide crystals
AU2003236243A1 (en) * 2002-04-15 2003-10-27 Ajinomoto Co., Inc. Novel nateglinide crystal
CN1304366C (zh) * 2002-04-15 2007-03-14 诺瓦提斯公司 N－(反式－4－异丙基环己基羰基)－d－苯丙氨酸的晶形
WO2003093222A1 (fr) * 2002-04-29 2003-11-13 Biocon Limited Nouvelle forme de n-(trans-4-isopropylcyclohexylcarbonyl)-d-phenylalanine
RU2324676C2 (ru) * 2002-04-29 2008-05-20 Байокон Лимитид Кристаллический n-(транс-4-изопропилциклогексилкарбонил)-d-фенилаланин формы с для лечения сахарного диабета типа 2 и способ его получения
US6861553B2 (en) * 2002-07-03 2005-03-01 Teva Pharmaceuticals Industries Ltd. Process for preparing nateglinide and intermediates thereof
EP1487782A1 (fr) * 2002-07-03 2004-12-22 Teva Pharmaceutical Industries Ltd. Procede de preparation du nateglinide et intermediaires
US7420084B2 (en) * 2002-07-18 2008-09-02 Teva Pharmaceutical Industries Ltd. Polymorphic forms of nateglinide
US7148376B2 (en) * 2002-07-18 2006-12-12 Teva Pharmaceutical Industries Ltd. Polymorphic forms of nateglinide
US7358390B2 (en) * 2002-07-18 2008-04-15 Teva Pharmaceutical Industries Ltd. Polymorphic forms of nateglinide
US20050075400A1 (en) * 2002-07-18 2005-04-07 Ronit Yahalomi Polymorphic forms of nateglinide
US7534913B2 (en) * 2002-07-18 2009-05-19 Teva Pharmaceutica Industries Ltd. Crystalline form of nateglinide
AU2003262928A1 (en) * 2002-08-28 2004-03-19 Dr. Reddy's Laboratories Limited Crystalline form of nateglinide and process for preparation thereof
US7449519B2 (en) * 2003-02-18 2008-11-11 Konishi Co., Ltd. Curing resin, method for producing same and curing resin composition
HU227073B1 (hu) 2003-07-10 2010-06-28 Richter Gedeon Nyrt Eljárás királisan tiszta N-(transz-4-izopropil-ciklohexilkarbonil)-D-fenil-alanin (nateglinid) és kristálymódosulatainak elõállítására, valamint a G-kristálymódosulata
MXPA06012793A (es) * 2004-05-07 2007-07-18 Teva Pharma Formas polimorficas de nateglinida.
US7425648B2 (en) 2005-01-03 2008-09-16 A.M.S.A. Anonima Materie Sintetiche E. Affini S.P.A. Process for the preparation of nateglinide, preferably in B-form
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
CA2622608C (fr) 2005-09-14 2014-08-19 Takeda Pharmaceutical Company Limited Administration d'inhibiteurs de dipeptidyl peptidase
EP2003113A4 (fr) * 2006-03-31 2012-07-18 Ajinomoto Kk Procede de production d'un compose chlorure d'acide carboxylique
CN103951583B (zh) * 2006-12-06 2016-01-06 科内图斯医药公司 一种抑制剂的结晶形式
JP5659224B2 (ja) 2009-05-15 2015-01-28 ノバルティス アーゲー アルドステロンシンターゼ阻害剤としてのアリールピリジン
ES2582395T3 (es) 2009-05-28 2016-09-12 Novartis Ag Derivados aminobutíricos sustituidos como inhibidores de neprilisina
MX2011012628A (es) 2009-05-28 2011-12-14 Novartis Ag Derivados amino-propionicos sustituidos como inhibidores de neprilisina.
WO2011041293A1 (fr) 2009-09-30 2011-04-07 Takeda Pharmaceutical Company Limited Dérivés pyrazolo [1, 5—a] pyrimidines comme inhibiteurs de kinase 1 régulatrice de signal d'apoptose
CN102712589B (zh) 2009-11-17 2015-05-13 诺华股份有限公司 作为醛固酮合酶抑制剂的芳基-吡啶衍生物
JO2967B1 (en) 2009-11-20 2016-03-15 نوفارتس ايه جي Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors
CN102666535B (zh) 2009-11-30 2015-02-25 诺华股份有限公司 作为醛固酮合酶抑制剂的咪唑衍生物
SI2531501T1 (sl) 2010-02-03 2014-04-30 Takeda Pharmaceutical Company Limited Inhibitorji kinaze-1, ki regulirajo signal apoptoze
US8877815B2 (en) 2010-11-16 2014-11-04 Novartis Ag Substituted carbamoylcycloalkyl acetic acid derivatives as NEP
US8673974B2 (en) 2010-11-16 2014-03-18 Novartis Ag Substituted amino bisphenyl pentanoic acid derivatives as NEP inhibitors
UY35144A (es) 2012-11-20 2014-06-30 Novartis Ag Miméticos lineales sintéticos de apelina para el tratamiento de insuficiencia cardiaca
JP6295277B2 (ja) 2013-02-14 2018-03-14 ノバルティス アーゲー Ｎｅｐ（中性エンドペプチダーゼ）阻害剤としての置換ビスフェニルブタン酸ホスホン酸誘導体
TW201536814A (zh) 2013-07-25 2015-10-01 Novartis Ag 用於治療心臟衰竭之合成環狀多肽
PE20160991A1 (es) 2013-07-25 2016-10-15 Novartis Ag Bioconjugados de polipeptidos de apelina sintetica
WO2016116842A1 (fr) 2015-01-23 2016-07-28 Novartis Ag Conjugués d'acides gras de l'apeline synthétique présentant une demi-vie améliorée
UY38072A (es) 2018-02-07 2019-10-01 Novartis Ag Compuestos derivados de éster butanoico sustituido con bisfenilo como inhibidores de nep, composiciones y combinaciones de los mismos
CN109369443A (zh) * 2018-11-05 2019-02-22 扬子江药业集团江苏海慈生物药业有限公司 一种新的那格列奈h晶型的制备方法

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* Cited by examiner, † Cited by third party
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US196222A (en) * 1877-10-16 Improvement in belt-tighteners
JPS6354321A (ja) * 1985-03-27 1988-03-08 Ajinomoto Co Inc 血糖降下剤

Also Published As

Publication number Publication date
JP2508949B2 (ja) 1996-06-19
ES2100291T3 (es) 1997-06-16
CA2114678C (fr) 1999-04-27
JPH05208943A (ja) 1993-08-20
LU90843I2 (fr) 2002-02-04
NL300063I1 (nl) 2001-12-01
DE69217762D1 (de) 1997-04-10
BR1100807A (pt) 1999-12-28
EP0526171A2 (fr) 1993-02-03
EP0526171B1 (fr) 1997-03-05
DK0526171T3 (da) 1997-08-25
DE10199058I2 (de) 2006-04-27
DE10199058I1 (de) 2002-01-24
EP0526171A3 (en) 1993-05-05
ATE149483T1 (de) 1997-03-15
NL300063I2 (nl) 2002-02-01
DE69217762T2 (de) 1997-10-09
CA2114678A1 (fr) 1995-08-02
US5488150A (en) 1996-01-30

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