LU91076I2 - Tulathromycin et ses sels pharmaceutiquement acceptables (draxxin). - Google Patents

Tulathromycin et ses sels pharmaceutiquement acceptables (draxxin).

Info

Publication number: LU91076I2
Authority: LU; Luxembourg
Prior art keywords: draxxin; tulathromycin; pharmaceutically acceptable; acceptable salts; salts
Prior art date: 1997-06-11

Application number

LU91076C

Other languages

English (en)

Other versions

LU91076I9 (en

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-06-11

Filing date

2004-05-05

Publication date

2004-07-05

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21959336&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU91076(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2004-05-05 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2004-07-05 Publication of LU91076I2 publication Critical patent/LU91076I2/fr

2018-07-02 Publication of LU91076I9 publication Critical patent/LU91076I9/fr

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biotechnology (AREA)
Veterinary Medicine (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Tropical Medicine & Parasitology (AREA)
Communicable Diseases (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

LU91076C 1997-06-11 2004-05-05 4"-substituted-9-deoxo-9a-aza-9a-homoerythromycin a derivatives LU91076I9 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US4934897P	1997-06-11	1997-06-11
PCT/IB1998/000839 WO1998056802A1 (fr)	1997-06-11	1998-05-29	Derives de homo-erythromycine -9-deoxo-9a-aza-9aa substitution en position 4

Publications (2)

Publication Number	Publication Date
LU91076I2 true LU91076I2 (fr)	2004-07-05
LU91076I9 LU91076I9 (en)	2018-07-02

Family

ID=21959336

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LU91076C LU91076I9 (en)	1997-06-11	2004-05-05	4"-substituted-9-deoxo-9a-aza-9a-homoerythromycin a derivatives

Country Status (49)

Country	Link
US (4)	US6420536B1 (fr)
EP (1)	EP0988310B9 (fr)
JP (2)	JP3315704B2 (fr)
KR (1)	KR100396168B1 (fr)
CN (4)	CN1793155B (fr)
AP (1)	AP1231A (fr)
AR (1)	AR013086A1 (fr)
AT (1)	ATE251173T1 (fr)
AU (1)	AU749816B2 (fr)
BG (1)	BG64391B1 (fr)
BR (1)	BRPI9810519B8 (fr)
CA (1)	CA2293823C (fr)
CO (1)	CO4950611A1 (fr)
CZ (1)	CZ298556B6 (fr)
DE (2)	DE122004000018I2 (fr)
DK (1)	DK0988310T3 (fr)
DZ (1)	DZ2514A1 (fr)
EA (1)	EA002441B1 (fr)
EG (1)	EG24081A (fr)
ES (1)	ES2205487T3 (fr)
FR (1)	FR04C0013I2 (fr)
GT (1)	GT199800077A (fr)
HN (1)	HN1998000086A (fr)
HR (1)	HRP980314B1 (fr)
HU (2)	HU228005B1 (fr)
ID (1)	ID22992A (fr)
IL (1)	IL132809A0 (fr)
IS (1)	IS1998B (fr)
LU (1)	LU91076I9 (fr)
MA (1)	MA24564A1 (fr)
ME (1)	ME00876B (fr)
MY (1)	MY123354A (fr)
NL (1)	NL300150I2 (fr)
NO (1)	NO316911B1 (fr)
NZ (2)	NZ500660A (fr)
OA (1)	OA11224A (fr)
PA (1)	PA8452201A1 (fr)
PE (1)	PE79699A1 (fr)
PL (1)	PL191601B1 (fr)
PT (1)	PT988310E (fr)
RS (1)	RS49675B (fr)
SI (1)	SI0988310T1 (fr)
SK (1)	SK284171B9 (fr)
TN (1)	TNSN98082A1 (fr)
TW (1)	TW472060B (fr)
UA (1)	UA67744C2 (fr)
UY (1)	UY25040A1 (fr)
WO (1)	WO1998056802A1 (fr)
ZA (1)	ZA985017B (fr)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
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HN1998000086A (es) *	1997-06-11	1999-03-08	Pfizer Prod Inc	Derivados de 9 - desofo - 9 aza - 9a - homoeritromicina a - c - 4 sustituidos.
EP1779853A3 (fr) *	1997-09-10	2010-01-27	Merial Ltd.	9a-azalides en tant qu'agents anti-microbiens à usage vétérinaire
ES2281136T3 (es) *	1997-09-10	2007-09-16	Merial Ltd.	Uso de 9a-azalidos como agentes antimicrobiales veterinarios.
US6339063B1 (en)	1997-09-10	2002-01-15	Merck & Co., Inc.	9a-azalides as veterinary antimicrobial agents
AP9801420A0 (en) *	1998-01-02	1998-12-31	Pfizer Prod Inc	Novel macrolides.
US6043227A (en) *	1998-08-19	2000-03-28	Pfizer Inc.	C11 carbamates of macrolide antibacterials
EP1437360A3 (fr) *	1998-08-19	2005-04-06	Pfizer Products Inc.	C11-carbamates des macrolides antibactériens
US6100240A (en) *	1998-10-09	2000-08-08	Pfizer Inc	Macrolide derivatives
CA2411293A1 (fr) *	1999-01-28	2000-07-28	Pfizer Products Inc.	Nouveaux azalides et procede de fabrication
DE60038610T2 (de) *	1999-05-18	2009-06-25	Pfizer Products Inc., Groton	Neue kristalline formen eines makrolidantibiotikums
HUP0201516A3 (en) *	1999-05-24	2003-03-28	Pfizer Prod Inc	13-methyl-erythromycin derivatives, process for their preparation and pharmaceutical compositions containing them
US6465437B1 (en) *	1999-06-30	2002-10-15	Pfizer Inc.	Diphosphate salt of a 4″-substituted-9-deoxo-9A-AZA-9A- homoerythromycin derivative and its pharmaceutical composition
US6764996B1 (en)	1999-08-24	2004-07-20	Abbott Laboratories	9a-azalides with antibacterial activity
DK1206476T3 (da) *	1999-08-24	2006-05-15	Abbott Lab	9a-azalider med antibakteriel virkning
US6608033B1 (en)	1999-08-27	2003-08-19	Pfizer Inc.	Treatment or prevention of coccidiosis
BRPI0017013B1 (pt)	2000-01-27	2015-07-14	Zoetis P Llc	Composição de antibiótico azalídeo e método para sua obtenção
BR0110382A (pt) *	2000-04-27	2003-06-24	Pfizer Prod Inc	Utilização de composições antibióticas azalida para o tratamento ou prevenção de uma infecção causada por bactérias ou protozoários em mamìferos
RU2263117C2 (ru) *	2001-04-27	2005-10-27	Пфайзер Продактс Инк.	Способ получения 4"-замещенных производных 9-деоксо-9а-аза-9а-гомоэритромицина а
AU2002317415A1 (en) *	2001-08-01	2003-02-17	Pfizer Products Inc.	Azalide antibiotic compositions
EP1638549A4 (fr)	2003-03-10	2011-06-15	Optimer Pharmaceuticals Inc	Nouveaux agents antibacteriens
WO2005030227A1 (fr)	2003-09-23	2005-04-07	Enanta Pharmaceuticals, Inc.	Derives 9a-azalide 11-3c-bicycliques
MXPA06005639A (es) *	2003-11-21	2006-08-17	Pfizer Prod Inc	Adyuvante antimicrobiano.
CN103030617A (zh) *	2004-03-16	2013-04-10	贝林格尔.英格海姆国际有限公司	吡喃葡萄糖基取代的苯基衍生物、含该化合物的药物、其用途及其制造方法
US7468428B2 (en) *	2004-03-17	2008-12-23	App Pharmaceuticals, Llc	Lyophilized azithromycin formulation
US20060116336A1 (en) *	2004-03-17	2006-06-01	American Pharmaceutical Partners, Inc.	Lyophilized azithromycin formulation
US7402568B2 (en)	2004-09-29	2008-07-22	Enanta Pharmaceuticals, Inc.	Bicyclic 9a-azalide derivatives
US7767797B1 (en) *	2004-09-30	2010-08-03	Synovo Gmbh	Macrocyclic compounds and methods of use thereof
US7271155B2 (en)	2005-01-07	2007-09-18	Enanta Pharmaceuticals, Inc.	9A, 11-2C-bicyclic 9a-azalide derivatives
ATE429921T1 (de) *	2005-01-14	2009-05-15	Glaxosmithkline Zagreb	9a-carbamoyl- und thiocarbamoylazalide mit antimalariawirkung
EP2214484A4 (fr)	2007-10-25	2013-01-02	Cempra Pharmaceuticals Inc	Procédé pour la préparation d'agents antibactériens macrolides
JP5711135B2 (ja)	2008-10-24	2015-04-30	センプラファーマシューティカルズ，インコーポレイテッド	胃腸疾患を治療するための方法
US9937194B1 (en) *	2009-06-12	2018-04-10	Cempra Pharmaceuticals, Inc.	Compounds and methods for treating inflammatory diseases
ES2608285T3 (es)	2009-09-10	2017-04-07	Cempra Pharmaceuticals, Inc.	Procedimientos para el tratamiento de paludismo, tuberculosis y enfermedades por MAC
MX361413B (es)	2010-03-22	2018-12-05	Cempra Pharmaceuticals Inc Star	Formas cristalinas de un macrólido y usos para las mismas.
CN102917708B (zh)	2010-05-20	2015-11-25	森普拉制药公司	制备大环内酯和酮内酯及其中间体的方法
EP2613630A4 (fr)	2010-09-10	2014-01-15	Cempra Pharmaceuticals Inc	Fluorocétolides formant des liaisons hydrogène pour traiter les maladies
WO2012038372A1 (fr)	2010-09-20	2012-03-29	Novartis Ag	Nouveau procédé de préparation de 9-déoxo-9a-aza-9a-homoérythromycine a modifiée dans le c-4'' du cycle cladinose par un groupe époxyde
EP2625185A4 (fr) *	2010-10-10	2014-03-26	Synovo Gmbh	Macrolides antiinflammatoires
WO2013004116A1 (fr) *	2011-07-06	2013-01-10	洛阳惠中兽药有限公司	Dérivé de 9a-aza-9a-érythromycine c-3-substituée et 9-désoxydée
CN102260306B (zh) *	2011-07-22	2012-07-18	山东鲁抗舍里乐药业有限公司	一种制备泰拉霉素的方法
EP2736915A1 (fr)	2011-07-27	2014-06-04	Farma GRS, d.o.o.	Nouvelles formes cristallines de tulathromycine
NZ700182A (en)	2012-03-27	2017-02-24	Cempra Pharmaceuticals Inc	Parenteral formulations for administering macrolide antibiotics
CN102786569B (zh) *	2012-09-07	2016-12-07	安徽中升药业有限公司	泰拉霉素中间体及其制备方法与泰拉霉素的制备方法
AU2014239959A1 (en)	2013-03-14	2015-10-01	Cempra Pharmaceuticals, Inc.	Methods for treating respiratory diseases and formulations therefor
CN105188712A (zh)	2013-03-15	2015-12-23	森普拉制药公司	用于制备大环内酯抗菌剂的收敛方法
EP3027634B1 (fr) *	2013-07-31	2018-03-21	Farma GRS, d.o.o.	Procédé de préparation de tulathromycine
CN103497227B (zh) *	2013-09-13	2015-09-30	青岛科技大学	一种泰拉菌素中间体的制备方法
CN104725446B (zh) *	2015-03-26	2017-10-27	宁夏泰瑞制药股份有限公司	一种从泰拉霉素粗品中分离泰拉霉素a和泰拉霉素b的方法
CN104861018A (zh) *	2015-06-17	2015-08-26	瑞普（天津）生物药业有限公司	一种泰拉菌素的制备方法
CN105646617A (zh) *	2016-01-21	2016-06-08	杭州海尔希畜牧科技有限公司	一种制备泰拉霉素的方法
FR3048612B1 (fr) *	2016-03-14	2020-10-02	Septeos	Tulathromycine potentialisee
CN106046077B (zh) *	2016-08-04	2019-07-26	湖北美天生物科技股份有限公司	一种泰拉霉素a的合成方法
CN108003207B (zh)	2017-12-19	2019-05-10	海门慧聚药业有限公司	制备泰拉霉素的方法
CN111087433B (zh) *	2018-10-23	2023-03-21	湖北美天生物科技股份有限公司	一种泰拉霉素中间体的制备方法

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SI8110592A8 (en) *	1981-03-06	1996-06-30	Pliva Pharm & Chem Works	Process for preparing of n-methyl-11-aza-10-deoxo-10-dihydroerythromycine a and derivatives thereof
US4474768A (en) *	1982-07-19	1984-10-02	Pfizer Inc.	N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
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CA2064634C (fr) *	1991-04-04	1998-08-04	James V. Heck	Derives de 9-desoxo-8a-aza-8a-homoerythromycine a modifies en positions 4"- et 8a
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EP0549040A1 (fr)	1991-12-20	1993-06-30	Merck & Co. Inc.	Méthodes pour fabriquer 4" dérivés de 9-désoxo-8a-aza-8a-alkyl-8a-homoérythromycin A
US5441939A (en) *	1994-03-04	1995-08-15	Pfizer Inc.	3"-desmethoxy derivatives of erythromycin and azithromycin
HN1998000086A (es)	1997-06-11	1999-03-08	Pfizer Prod Inc	Derivados de 9 - desofo - 9 aza - 9a - homoeritromicina a - c - 4 sustituidos.
UA70972C2 (uk)	1998-11-20	2004-11-15	Пфайзер Продактс Інк.	13-членні азаліди і їх застосування як антибіотиків

1998
- 1998-05-03 HN HN1998000086A patent/HN1998000086A/es unknown
- 1998-05-27 PA PA19988452201A patent/PA8452201A1/es unknown
- 1998-05-29 ID IDW991569A patent/ID22992A/id unknown
- 1998-05-29 BR BRPI9810519A patent/BRPI9810519B8/pt not_active IP Right Cessation
- 1998-05-29 AT AT98920693T patent/ATE251173T1/de active
- 1998-05-29 PT PT98920693T patent/PT988310E/pt unknown
- 1998-05-29 ES ES98920693T patent/ES2205487T3/es not_active Expired - Lifetime
- 1998-05-29 KR KR10-1999-7011642A patent/KR100396168B1/ko not_active Expired - Lifetime
- 1998-05-29 CN CN2006100513455A patent/CN1793155B/zh not_active Expired - Lifetime
- 1998-05-29 CN CNB2004100491122A patent/CN1243766C/zh not_active Expired - Lifetime
- 1998-05-29 HU HU0002209A patent/HU228005B1/hu active Protection Beyond IP Right Term
- 1998-05-29 PL PL337505A patent/PL191601B1/pl unknown
- 1998-05-29 NZ NZ500660A patent/NZ500660A/en not_active IP Right Cessation
- 1998-05-29 US US09/424,104 patent/US6420536B1/en not_active Expired - Lifetime
- 1998-05-29 SI SI9830572T patent/SI0988310T1/xx unknown
- 1998-05-29 SK SK168399A patent/SK284171B9/sk not_active IP Right Cessation
- 1998-05-29 JP JP50193599A patent/JP3315704B2/ja not_active Expired - Lifetime
- 1998-05-29 AU AU73475/98A patent/AU749816B2/en not_active Expired
- 1998-05-29 ME MEP-1999-586A patent/ME00876B/me unknown
- 1998-05-29 RS YUP-586/99A patent/RS49675B/sr unknown
- 1998-05-29 DK DK98920693T patent/DK0988310T3/da active
- 1998-05-29 EA EA199901015A patent/EA002441B1/ru not_active IP Right Cessation
- 1998-05-29 CA CA002293823A patent/CA2293823C/fr not_active Expired - Lifetime
- 1998-05-29 NZ NZ514871A patent/NZ514871A/en not_active IP Right Cessation
- 1998-05-29 DE DE122004000018C patent/DE122004000018I2/de active Active
- 1998-05-29 DE DE69818665T patent/DE69818665T2/de not_active Expired - Lifetime
- 1998-05-29 EP EP98920693A patent/EP0988310B9/fr not_active Expired - Lifetime
- 1998-05-29 WO PCT/IB1998/000839 patent/WO1998056802A1/fr not_active Ceased
- 1998-05-29 CN CNB988059223A patent/CN1172947C/zh not_active Expired - Lifetime
- 1998-05-29 CN CN200910145318A patent/CN101691390A/zh active Pending
- 1998-05-29 CZ CZ0442199A patent/CZ298556B6/cs not_active IP Right Cessation
- 1998-05-29 IL IL13280998A patent/IL132809A0/xx not_active IP Right Cessation
- 1998-05-29 UA UA99126736A patent/UA67744C2/uk unknown
- 1998-06-04 AP APAP/P/1998/001255A patent/AP1231A/en active
- 1998-06-08 PE PE1998000471A patent/PE79699A1/es not_active Application Discontinuation
- 1998-06-09 MY MYPI98002575A patent/MY123354A/en unknown
- 1998-06-09 AR ARP980102706A patent/AR013086A1/es active IP Right Grant
- 1998-06-09 EG EG64098A patent/EG24081A/xx active
- 1998-06-10 TN TNTNSN98082A patent/TNSN98082A1/fr unknown
- 1998-06-10 MA MA25107A patent/MA24564A1/fr unknown
- 1998-06-10 CO CO98033232A patent/CO4950611A1/es unknown
- 1998-06-10 DZ DZ980124A patent/DZ2514A1/fr active
- 1998-06-10 ZA ZA9805017A patent/ZA985017B/xx unknown
- 1998-06-10 GT GT199800077A patent/GT199800077A/es unknown
- 1998-06-11 HR HR980314A patent/HRP980314B1/xx not_active IP Right Cessation
- 1998-06-11 UY UY25040A patent/UY25040A1/es not_active IP Right Cessation
1999
- 1999-02-26 TW TW087109077A patent/TW472060B/zh not_active IP Right Cessation
- 1999-11-16 IS IS5252A patent/IS1998B/is unknown
- 1999-12-03 OA OA9900268A patent/OA11224A/en unknown
- 1999-12-03 BG BG103945A patent/BG64391B1/bg unknown
- 1999-12-10 NO NO996106A patent/NO316911B1/no not_active IP Right Cessation
2001
- 2001-11-21 US US09/989,936 patent/US20020061858A1/en not_active Abandoned
2002
- 2002-03-13 JP JP2002068432A patent/JP2002316933A/ja active Pending
- 2002-10-18 US US10/273,879 patent/US6777393B2/en not_active Expired - Lifetime
2004
- 2004-03-26 US US10/810,922 patent/US6936592B2/en not_active Expired - Lifetime
- 2004-05-04 FR FR04C0013C patent/FR04C0013I2/fr active Active
- 2004-05-05 LU LU91076C patent/LU91076I9/fr unknown
- 2004-05-10 NL NL300150C patent/NL300150I2/nl unknown
2012
- 2012-11-26 HU HUS1200028C patent/HUS1200028I1/hu unknown

Also Published As

Publication number	Publication date
CN1793155A (zh)	2006-06-28
RS49675B (sr)	2007-11-15
US20040180842A1 (en)	2004-09-16
CN1566129A (zh)	2005-01-19
CZ442199A3 (cs)	2000-07-12
HUS1200028I1 (hu)	2016-08-29
KR100396168B1 (ko)	2003-08-27
PL337505A1 (en)	2000-08-28
DZ2514A1 (fr)	2003-02-01
DK0988310T3 (da)	2003-12-15
AP1231A (en)	2003-12-11
US6777393B2 (en)	2004-08-17
HK1028048A1 (en)	2001-02-02
TNSN98082A1 (fr)	2005-03-15
CN1243766C (zh)	2006-03-01
HUP0002209A2 (hu)	2000-12-28
PL191601B1 (pl)	2006-06-30
US6420536B1 (en)	2002-07-16
NO996106L (no)	2000-02-10
DE69818665T2 (de)	2004-04-29
HK1068893A1 (en)	2005-07-29
EA199901015A1 (ru)	2000-06-26
EP0988310B1 (fr)	2003-10-01
HK1088014A1 (zh)	2006-10-27
PA8452201A1 (es)	2000-05-24
ATE251173T1 (de)	2003-10-15
AU749816B2 (en)	2002-07-04
AR013086A1 (es)	2000-12-13
EP0988310B9 (fr)	2006-03-08
BG64391B1 (bg)	2004-12-30
PE79699A1 (es)	1999-08-25
BRPI9810519B1 (pt)	2012-02-22
NZ500660A (en)	2002-03-01
SI0988310T1 (en)	2004-02-29
UA67744C2 (uk)	2004-07-15
BG103945A (bg)	2000-07-31
CZ298556B6 (cs)	2007-11-07
WO1998056802A1 (fr)	1998-12-17
JP2000514098A (ja)	2000-10-24
AU7347598A (en)	1998-12-30
DE69818665D1 (de)	2003-11-06
HRP980314A2 (en)	1999-04-30
BRPI9810519B8 (pt)	2022-11-16
IS1998B (is)	2005-03-15
ZA985017B (en)	1999-12-17
CN101691390A (zh)	2010-04-07
ME00876B (me)	2012-06-20
CN1172947C (zh)	2004-10-27
BRPI9810519A (pt)	2000-09-19
HN1998000086A (es)	1999-03-08
ES2205487T3 (es)	2004-05-01
NL300150I1 (nl)	2004-08-02
EP0988310A1 (fr)	2000-03-29
GT199800077A (es)	1999-12-02
ID22992A (id)	1999-12-23
MY123354A (en)	2006-05-31
JP2002316933A (ja)	2002-10-31
CO4950611A1 (es)	2000-09-01
NO316911B1 (no)	2004-06-21
EA002441B1 (ru)	2002-04-25
JP3315704B2 (ja)	2002-08-19
NL300150I2 (nl)	2004-09-01
DE122004000018I1 (de)	2004-09-30
CN1793155B (zh)	2010-05-12
AP9801255A0 (en)	1998-06-30
SK284171B9 (sk)	2005-03-04
NZ514871A (en)	2003-08-29
YU58699A (fr)	2002-08-12
IL132809A0 (en)	2001-03-19
HRP980314B1 (en)	2004-04-30
TW472060B (en)	2002-01-11
KR20010013632A (ko)	2001-02-26
UY25040A1 (es)	2000-09-29
HU228005B1 (en)	2012-08-28
MA24564A1 (fr)	1998-12-31
CA2293823A1 (fr)	1998-12-17
US6936592B2 (en)	2005-08-30
US20020061858A1 (en)	2002-05-23
SK168399A3 (en)	2000-11-07
CN1259136A (zh)	2000-07-05
EG24081A (en)	2008-05-11
OA11224A (en)	2003-07-16
IS5252A (is)	1999-11-16
SK284171B6 (sk)	2004-10-05
HUP0002209A3 (en)	2003-05-28
FR04C0013I1 (fr)	2004-06-11
DE122004000018I2 (de)	2011-01-13
NO996106D0 (no)	1999-12-10
US20040023896A1 (en)	2004-02-05
LU91076I9 (en)	2018-07-02
PT988310E (pt)	2003-12-31
CA2293823C (fr)	2004-02-17
FR04C0013I2 (fr)	2005-10-21

Publication	Publication Date	Title
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LU91147I2 (fr)	2005-05-17	Pemetrexed et ses sels pharmaceutiquement acceptables.
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LU91673I2 (fr)	2010-06-07	"Dronédarone et ses dérivés pharmaceutiquement acceptables (MULTAQ)"
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EE200000438A (et)	2001-12-17	Farmatseutiliselt aktiivne morfolinool
LU92024I2 (fr)	2012-08-20	Pasireotide et ses dérivés pharmaceutiquement acceptables (SIGNIFOR)
NO995623L (no)	2000-01-12	Sannsynlighetsspill
LU91163I2 (fr)	2005-06-20	Hydrobromure de darifénacine et ses dérivés pharmaceutiquement acceptables (EMSELEX.
EE9900290A (et)	2000-02-15	3-heterotsüklüül-asendatud bensoüülderivaadid
LU91269I2 (fr)	2006-09-26	Rotigotine et ses dérivés pharmaceutiquement acceptables (neupro)
LU91363I2 (fr)	2007-11-12	Méthoxy polyéthylène glycol-époétine bêta et ses sels pharmaceutiquement acceptables (MIRCERA)
LU91819I2 (fr)	2011-08-01	Ticagrelor ou ses sels pharmacologiquement acceptables
LU91849I2 (fr)	2011-09-27	Cimicoxib et ses dérivés pharmaceutiquement acceptables - CIMALGEX®.
NO2005007I2 (no)	2008-02-11	Pemetrexed og farmasoytisk akseptable salter derav
TR199800988A3 (tr)	1998-12-21	5' Deoksi-Sitidin türevleri.
DK1032579T3 (da)	2003-08-25	Carbohydratderivater
DE69406255D1 (de)	1997-11-20	Carbonatderivate
DE69717068D1 (de)	2002-12-19	Mehrwalzenbrecher