LU91220I2 - Tipranavir ou un de ses sels pharmaceutiques (aptivus) - Google Patents

Tipranavir ou un de ses sels pharmaceutiques (aptivus)

Info

Publication number: LU91220I2
Authority: LU; Luxembourg
Prior art keywords: aptivus; tipranavir; ones; pharmaceutical salt; pyran
Prior art date: 1994-05-06

Application number

LU91220C

Other languages

English (en)

Original Assignee

Upjohn Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-05-06

Filing date

2006-02-08

Publication date

2006-04-10

2006-02-08 Application filed by Upjohn Co filed Critical Upjohn Co

2006-04-10 Publication of LU91220I2 publication Critical patent/LU91220I2/fr

Links

SUJUHGSWHZTSEU-FYBSXPHGSA-N tipranavir Chemical compound C([C@@]1(CCC)OC(=O)C([C@H](CC)C=2C=C(NS(=O)(=O)C=3N=CC(=CC=3)C(F)(F)F)C=CC=2)=C(O)C1)CC1=CC=CC=C1 SUJUHGSWHZTSEU-FYBSXPHGSA-N 0.000 title 2
SUJUHGSWHZTSEU-UHFFFAOYSA-N Tipranavir Natural products C1C(O)=C(C(CC)C=2C=C(NS(=O)(=O)C=3N=CC(=CC=3)C(F)(F)F)C=CC=2)C(=O)OC1(CCC)CCC1=CC=CC=C1 SUJUHGSWHZTSEU-UHFFFAOYSA-N 0.000 title 1
229940030139 aptivus Drugs 0.000 title 1
150000003839 salts Chemical class 0.000 title 1
229960000838 tipranavir Drugs 0.000 title 1
241001430294 unidentified retrovirus Species 0.000 abstract 2
QBDAFARLDLCWAT-UHFFFAOYSA-N 2,3-dihydropyran-6-one Chemical class O=C1OCCC=C1 QBDAFARLDLCWAT-UHFFFAOYSA-N 0.000 abstract 1
ZPSJGADGUYYRKE-UHFFFAOYSA-N 2H-pyran-2-one Chemical class O=C1C=CC=CO1 ZPSJGADGUYYRKE-UHFFFAOYSA-N 0.000 abstract 1
VXIXUWQIVKSKSA-UHFFFAOYSA-N 4-hydroxycoumarin Chemical class C1=CC=CC2=C1OC(=O)C=C2O VXIXUWQIVKSKSA-UHFFFAOYSA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
210000004962 mammalian cell Anatomy 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/74—Benzo[b]pyrans, hydrogenated in the carbocyclic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Virology (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Tropical Medicine & Parasitology (AREA)
AIDS & HIV (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrane Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

LU91220C 1994-05-06 2006-02-08 Tipranavir ou un de ses sels pharmaceutiques (aptivus) LU91220I2 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US23881794A	1994-05-06	1994-05-06
US34936194A	1994-12-02	1994-12-02

Publications (1)

Publication Number	Publication Date
LU91220I2 true LU91220I2 (fr)	2006-04-10

Family

ID=26931995

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LU91220C LU91220I2 (fr)	1994-05-06	2006-02-08	Tipranavir ou un de ses sels pharmaceutiques (aptivus)

Country Status (32)

Country	Link
US (2)	US5852195A (fr)
EP (1)	EP0758327B1 (fr)
JP (1)	JP3883206B2 (fr)
KR (1)	KR100445929B1 (fr)
CN (2)	CN1329378C (fr)
AT (1)	ATE236894T1 (fr)
AU (2)	AU701965B2 (fr)
BR (1)	BR9507615A (fr)
CA (2)	CA2560489C (fr)
CO (1)	CO4810313A1 (fr)
CZ (1)	CZ296515B6 (fr)
DE (2)	DE69530294T2 (fr)
DK (1)	DK0758327T3 (fr)
ES (1)	ES2192201T3 (fr)
FI (1)	FI117387B (fr)
FR (1)	FR05C0047I2 (fr)
HU (1)	HU228057B1 (fr)
IL (3)	IL129871A (fr)
LU (1)	LU91220I2 (fr)
MX (1)	MX9605391A (fr)
MY (2)	MY127701A (fr)
NL (1)	NL300216I2 (fr)
NO (2)	NO315799B1 (fr)
NZ (1)	NZ285510A (fr)
PE (1)	PE23196A1 (fr)
PL (1)	PL190540B1 (fr)
PT (1)	PT758327E (fr)
RU (1)	RU2139284C1 (fr)
SI (1)	SI0758327T1 (fr)
SK (1)	SK284407B6 (fr)
TW (1)	TW504507B (fr)
WO (1)	WO1995030670A2 (fr)

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ATE265847T1 (de) *	1997-07-29	2004-05-15	Upjohn Co	Selbstemulgierbare formulierung enthaltend lipophile verbindungen
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HU228923B1 (en)	1997-07-29	2013-06-28	Upjohn Co	Pharmaceutical composition for acidic lipophilic compounds in a form of a self-emulsifying formulation
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US10800725B2 (en)	2010-09-09	2020-10-13	Richard H. Ebright	Arylpropionyl-triketone antibacterial agents
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1995
- 1995-05-01 IL IL12987195A patent/IL129871A/xx not_active IP Right Cessation
- 1995-05-04 US US08/809,224 patent/US5852195A/en not_active Expired - Lifetime
- 1995-05-04 SK SK1384-96A patent/SK284407B6/sk not_active IP Right Cessation
- 1995-05-04 WO PCT/US1995/005219 patent/WO1995030670A2/fr not_active Ceased
- 1995-05-04 SI SI9530660T patent/SI0758327T1/xx unknown
- 1995-05-04 CN CNB2004100346805A patent/CN1329378C/zh not_active Expired - Lifetime
- 1995-05-04 MX MX9605391A patent/MX9605391A/es active IP Right Grant
- 1995-05-04 PL PL95317061A patent/PL190540B1/pl unknown
- 1995-05-04 CZ CZ0317296A patent/CZ296515B6/cs not_active IP Right Cessation
- 1995-05-04 DE DE69530294T patent/DE69530294T2/de not_active Expired - Lifetime
- 1995-05-04 HU HU9603074A patent/HU228057B1/hu active Protection Beyond IP Right Term
- 1995-05-04 AT AT95918864T patent/ATE236894T1/de active
- 1995-05-04 BR BR9507615A patent/BR9507615A/pt active Search and Examination
- 1995-05-04 NZ NZ285510A patent/NZ285510A/en not_active IP Right Cessation
- 1995-05-04 RU RU96123286A patent/RU2139284C1/ru active
- 1995-05-04 ES ES95918864T patent/ES2192201T3/es not_active Expired - Lifetime
- 1995-05-04 DE DE1995630294 patent/DE122006000014I2/de active Active
- 1995-05-04 CA CA002560489A patent/CA2560489C/fr not_active Expired - Lifetime
- 1995-05-04 DK DK95918864T patent/DK0758327T3/da active
- 1995-05-04 KR KR1019960706245A patent/KR100445929B1/ko not_active Expired - Lifetime
- 1995-05-04 PT PT95918864T patent/PT758327E/pt unknown
- 1995-05-04 CN CNB951935534A patent/CN1154642C/zh not_active Expired - Lifetime
- 1995-05-04 TW TW084104473A patent/TW504507B/zh not_active IP Right Cessation
- 1995-05-04 AU AU24626/95A patent/AU701965B2/en not_active Expired
- 1995-05-04 CA CA002187523A patent/CA2187523C/fr not_active Expired - Lifetime
- 1995-05-04 JP JP52901695A patent/JP3883206B2/ja not_active Expired - Lifetime
- 1995-05-04 EP EP95918864A patent/EP0758327B1/fr not_active Expired - Lifetime
- 1995-05-05 MY MYPI95001195A patent/MY127701A/en unknown
- 1995-05-05 MY MYPI20051072A patent/MY149862A/en unknown
- 1995-05-05 CO CO95018810A patent/CO4810313A1/es unknown
- 1995-05-08 PE PE1995268036A patent/PE23196A1/es not_active IP Right Cessation
1996
- 1996-05-01 IL IL11356796A patent/IL113567A/xx not_active IP Right Cessation
- 1996-11-05 FI FI964441A patent/FI117387B/fi not_active IP Right Cessation
- 1996-11-05 NO NO19964676A patent/NO315799B1/no not_active IP Right Cessation
1998
- 1998-11-09 US US09/188,998 patent/US6169181B1/en not_active Expired - Lifetime
1999
- 1999-04-09 AU AU23686/99A patent/AU718117B2/en not_active Expired
- 1999-05-10 IL IL12987199A patent/IL129871A0/xx unknown
2005
- 2005-12-22 FR FR05C0047C patent/FR05C0047I2/fr active Active
2006
- 2006-01-20 NL NL300216C patent/NL300216I2/nl unknown
- 2006-02-08 LU LU91220C patent/LU91220I2/fr unknown
- 2006-03-02 NO NO2006003C patent/NO2006003I2/no unknown

Also Published As

Publication number	Publication date
JP3883206B2 (ja)	2007-02-21
IL129871A0 (en)	2000-02-29
FR05C0047I2 (fr)	2007-10-19
PT758327E (pt)	2003-08-29
JPH09512821A (ja)	1997-12-22
MY149862A (en)	2013-10-31
DE122006000014I1 (de)	2006-11-16
CN1539825A (zh)	2004-10-27
KR100445929B1 (ko)	2005-09-30
SI0758327T1 (en)	2003-08-31
DE69530294T2 (de)	2003-12-24
DE122006000014I2 (de)	2007-03-29
CA2187523A1 (fr)	1995-11-16
TW504507B (en)	2002-10-01
SK284407B6 (sk)	2005-03-04
EP0758327A1 (fr)	1997-02-19
FI964441A0 (fi)	1996-11-05
NO964676D0 (no)	1996-11-05
ES2192201T3 (es)	2003-10-01
IL129871A (en)	2003-11-23
MX9605391A (es)	1997-12-31
NL300216I1 (nl)	2006-04-03
US5852195A (en)	1998-12-22
CA2560489C (fr)	2010-01-12
CA2560489A1 (fr)	1995-11-16
DK0758327T3 (da)	2003-07-28
HU228057B1 (en)	2012-09-28
WO1995030670A2 (fr)	1995-11-16
CN1154642C (zh)	2004-06-23
CN1150424A (zh)	1997-05-21
CA2187523C (fr)	2006-11-21
IL113567A (en)	2003-05-29
FI117387B (fi)	2006-09-29
CZ317296A3 (en)	1997-04-16
KR970702858A (ko)	1997-06-10
HUT77601A (hu)	1998-06-29
RU2139284C1 (ru)	1999-10-10
NO2006003I2 (no)	2008-10-20
EP0758327B1 (fr)	2003-04-09
HK1066796A1 (zh)	2005-04-01
BR9507615A (pt)	1997-09-09
NO315799B1 (no)	2003-10-27
NO964676L (no)	1997-01-06
ATE236894T1 (de)	2003-04-15
CZ296515B6 (cs)	2006-04-12
HU9603074D0 (en)	1997-01-28
MY127701A (en)	2006-12-29
DE69530294D1 (de)	2003-05-15
NL300216I2 (nl)	2006-06-01
PL317061A1 (en)	1997-03-03
PL190540B1 (pl)	2005-12-30
NO2006003I1 (no)	2006-03-13
CN1329378C (zh)	2007-08-01
FR05C0047I1 (fr)	2006-03-10
AU2462695A (en)	1995-11-29
WO1995030670A3 (fr)	1996-04-25
SK138496A3 (en)	1997-06-04
NZ285510A (en)	1998-03-25
AU701965B2 (en)	1999-02-11
CO4810313A1 (es)	1999-06-30
US6169181B1 (en)	2001-01-02
AU2368699A (en)	1999-06-03
PE23196A1 (es)	1996-06-07
HK1084667A1 (en)	2006-08-04
AU718117B2 (en)	2000-04-06
FI964441L (fi)	1996-11-05

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LU91220I2 (fr)	2006-04-10	Tipranavir ou un de ses sels pharmaceutiques (aptivus)
MY119031A (en)	2005-03-31	Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating hiv and other retroviruses
NO953070D0 (no)	1995-08-04	4-hydroksy-benzopyran-2-oner og 4-hydroksysykloalkyl[BÅpyran-2-oner anvendbare for behandling av retrovirusinfeksjoner
TR199700844T1 (xx)	1998-01-21	Pirazolil-Benzoil T�revleri.
AU603525B2 (en)	1990-11-15	Tetrazole intermediates to antihypertensive compounds
DE69637380D1 (en)	2008-02-07	Bis-sulfonamid-hydroxyethylamino-derivate als inhibitoren retroviraler proteasen
ES2150664T3 (es)	2000-12-01	Nuevos derivados peptidos.
FR2380266A1 (fr)	1978-09-08	Molybdates d'amines heterocycliques, procede d'obtention et application
ATE189894T1 (de)	2000-03-15	Naphthamidderivate von 3-beta-amino azabicyclooctan oder nonan als antipsychotische arzneimittel
FI910366A0 (fi)	1991-01-24	Menetelmä deoksimulundokandiinin valmistamiseksi
NO912985D0 (no)	1991-07-31	Forbedret system for transdermal applikasjon av farmasoeytisk aktive forbindelser ved regulert ph.
WO1995022544A3 (fr)	1996-09-26	Derives substitues de 1,3,8-triaza-spiro(4,5)-decan-4-one utiles comme progeniteurs de produits pharmaceutiques
SU666804A1 (ru)	1998-07-10	S-метилсульфониевые соли 3,5-дифенил-2-тиабицикло[4,4,0] декана или дец-5-ена, проявляющие антимикробную активность
IT8985649A0 (it)	1989-09-19	Lamierini per statori e/o rotori di trasduttori di posizione angolare (resolver).