LU91603I2 - Eslicarbazepine acetate (Zebinix - eslicarbazepineacetate) Composé: énantiomère S de la Licarbazepi ne - Google Patents

Eslicarbazepine acetate (Zebinix - eslicarbazepineacetate) Composé: énantiomère S de la Licarbazepi ne

Info

Publication number: LU91603I2
Authority: LU; Luxembourg
Prior art keywords: zebinix; licarbazepi; eslicarbazepineacetate; enantiomer; compound
Prior art date: 2001-05-25

Application number

LU91603C

Other languages

English (en)

Original Assignee

Bial Portela & Ca Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-05-25

Filing date

2009-08-28

Publication date

2009-10-28

2009-08-28 Application filed by Bial Portela & Ca Sa filed Critical Bial Portela & Ca Sa

2009-10-28 Publication of LU91603I2 publication Critical patent/LU91603I2/fr

Links

229960003233 eslicarbazepine acetate Drugs 0.000 title 3
QIALRBLEEWJACW-INIZCTEOSA-N eslicarbazepine acetate Chemical compound CC(=O)O[C@H]1CC2=CC=CC=C2N(C(N)=O)C2=CC=CC=C12 QIALRBLEEWJACW-INIZCTEOSA-N 0.000 title 2
150000001875 compounds Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Epoxy Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Catalysts (AREA)

LU91603C 2001-05-25 2009-08-28 Eslicarbazepine acetate (Zebinix - eslicarbazepineacetate) Composé: énantiomère S de la Licarbazepi ne LU91603I2 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0112812.3A GB0112812D0 (en)	2001-05-25	2001-05-25	Mthd for preparation of 10, 11-dihydro-10-hydroxy-5H-dibenz/B,F/azepine-5-c arboxamide and 10,11-dihydro-10-oxo-5H-dibenz/B,F/azepine-5-carb oxamide therefrom
PCT/GB2002/002356 WO2002096881A1 (fr)	2001-05-25	2002-05-22	Procede de preparation du 10,11-dihydro-10-hydroxy-5h-dibenz/b,f/azepine-5-carboxamide et du 10,11-dihydro-10-0x0-5h-dibenz/b,f/azepine-5-carboxamide

Publications (1)

Publication Number	Publication Date
LU91603I2 true LU91603I2 (fr)	2009-10-28

Family

ID=9915332

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LU91603C LU91603I2 (fr)	2001-05-25	2009-08-28	Eslicarbazepine acetate (Zebinix - eslicarbazepineacetate) Composé: énantiomère S de la Licarbazepi ne

Country Status (23)

Country	Link
US (1)	US7241886B2 (fr)
EP (2)	EP1958938B1 (fr)
JP (3)	JP4323309B2 (fr)
KR (1)	KR100931916B1 (fr)
CN (2)	CN101172967A (fr)
AR (1)	AR035460A1 (fr)
AT (2)	ATE400560T1 (fr)
AU (2)	AU2002307863B8 (fr)
BR (1)	BR0210019A (fr)
CA (2)	CA2448094C (fr)
CY (3)	CY1108345T1 (fr)
CZ (1)	CZ303130B6 (fr)
DE (2)	DE60239842D1 (fr)
DK (2)	DK1958938T3 (fr)
ES (2)	ES2305299T3 (fr)
GB (1)	GB0112812D0 (fr)
HU (1)	HU230019B1 (fr)
LU (1)	LU91603I2 (fr)
MX (1)	MXPA03010793A (fr)
PL (1)	PL215305B1 (fr)
RU (2)	RU2311411C2 (fr)
SI (1)	SI1399424T1 (fr)
WO (1)	WO2002096881A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0303615D0 (en) *	2003-02-17	2003-03-19	Novartis Ag	Use of organic compounds
ITMI20042230A1 (it)	2004-11-19	2005-02-19	Farchemia Srl	Procedimento per la preparazione della 10,11-diidro-10 idrossi-5h-dibenz-b,f-azepin-5carbossiammide
ITMI20042291A1 (it)	2004-11-26	2005-02-26	Farchema S R L	Procedimento per la preparazione della -s-piu-10,11-diidro-10-idrossi-5h-dibenz-b,f-azepin-5-carbossiammide
GB2422149A (en) *	2005-01-14	2006-07-19	Portela & Ca Sa	Process for the preparation of 10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
US20060252745A1 (en) *	2005-05-06	2006-11-09	Almeida Jose L D	Methods of preparing pharmaceutical compositions comprising eslicarbazepine acetate and methods of use
GB0515690D0 (en)	2005-07-29	2005-09-07	Portela & Ca Sa	Asymmetric catalytic reduction
GB0517740D0 (en) *	2005-08-31	2005-10-12	Novartis Ag	Organic compounds
GB0700773D0 (en)	2007-01-15	2007-02-21	Portela & Ca Sa	Drug therapies
US8372431B2 (en) *	2007-10-26	2013-02-12	Bial-Portela & C.A., S.A.	Pharmaceutical composition comprising licarbazepine acetate
UA106384C2 (ru)	2009-07-27	2014-08-26	БИАЛ-ПОРТЕЛА энд КА., С.А.	ПРИМЕНЕНИЕ ПРОИЗВОДНЫХ 5H-ДИБЕНЗ/б,ф/АЗЕПИН-5-КАРБОКСАМИДА ДЛЯ ЛЕЧЕНИЯ ФИБРОМИАЛГИИ
WO2013008194A2 (fr)	2011-07-13	2013-01-17	Ranbaxy Laboratories Limited	Procédé de préparation et de purification d'acétate d'eslicarbazépine et de ses intermédiaires
EP2900640A1 (fr)	2012-09-26	2015-08-05	Ranbaxy Laboratories Limited	Procédé de préparation d'oxcarbazépine et son utilisation en tant qu'intermédiaire dans la préparation d'acétate d'eslicarbazépine
AU2016324165B2 (en)	2015-09-16	2020-07-02	PetaOmics, Inc.	Methods and compositions for genomic target enrichment and selective DNA sequencing
US12492423B2 (en)	2015-09-16	2025-12-09	PetaOmics, Inc.	Methods and compositions for genomic target enrichment and selective DNA sequencing
CN111943347B (zh) *	2020-07-16	2022-08-30	同济大学	一种铜离子活化过氧乙酸去除废水中卡马西平的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5439390B2 (fr) *	1971-09-30	1979-11-27
BE789320A (fr) *	1971-09-30	1973-03-27	Takeda Chemical Industries Ltd	Derives de dibenzoxirenazepine
CH633271A5 (en) *	1978-04-18	1982-11-30	Ciba Geigy Ag	Process for the rearrangement of 10,11-epoxy-10,11-dihydro-5H-dibenz[b,f]azepines to give 10-oxo-10,11-dihydro-5H-dibenz(b,f)azepines
CH642950A5 (en) *	1979-10-30	1984-05-15	Ciba Geigy Ag	Process for the preparation of 10-oxo-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide
IT1272897B (it) *	1995-01-13	1997-07-01	I F C Iniziative Finanziaarie	Processo per la produzione di 10-oxo-10,11-diidro-sh- -dibenz(b,f) azepin-5-carbossiammide
PT101732B (pt) *	1995-06-30	1997-12-31	Portela & Ca Sa	Novas di-hidrodibenzo<b,f>azepinas substituidas processo para a sua preparacao composicoes farmaceuticas que as contem e utilizacao dos novos compostos na preparacao de composicoes farmaceuticas empregues em doencas do sistema nervoso
PT101876B (pt) *	1996-05-27	1999-09-30	Portela & Ca Sa	Novos derivados de 10,11-di-hidro-10-oxo-5h-dibenzo(b,f)azepina-5-carboxamida
AT408224B (de) *	1999-03-15	2001-09-25	Dsm Fine Chem Austria Gmbh	Verfahren zur herstellung von oxcarbazepin

2001
- 2001-05-25 GB GBGB0112812.3A patent/GB0112812D0/en not_active Ceased
2002
- 2002-05-22 BR BR0210019-3A patent/BR0210019A/pt active Search and Examination
- 2002-05-22 DK DK08075527.5T patent/DK1958938T3/da active
- 2002-05-22 DE DE60239842T patent/DE60239842D1/de not_active Expired - Lifetime
- 2002-05-22 HU HU0400296A patent/HU230019B1/hu unknown
- 2002-05-22 AT AT02774050T patent/ATE400560T1/de active
- 2002-05-22 EP EP08075527A patent/EP1958938B1/fr not_active Expired - Lifetime
- 2002-05-22 ES ES02774050T patent/ES2305299T3/es not_active Expired - Lifetime
- 2002-05-22 AU AU2002307863A patent/AU2002307863B8/en not_active Ceased
- 2002-05-22 ES ES08075527T patent/ES2362688T3/es not_active Expired - Lifetime
- 2002-05-22 CN CNA2007101939981A patent/CN101172967A/zh active Pending
- 2002-05-22 KR KR1020037015323A patent/KR100931916B1/ko not_active Expired - Fee Related
- 2002-05-22 EP EP02774050A patent/EP1399424B8/fr not_active Expired - Lifetime
- 2002-05-22 DK DK02774050T patent/DK1399424T3/da active
- 2002-05-22 MX MXPA03010793A patent/MXPA03010793A/es active IP Right Grant
- 2002-05-22 SI SI200230717T patent/SI1399424T1/sl unknown
- 2002-05-22 CN CN028105915A patent/CN1511141B/zh not_active Expired - Fee Related
- 2002-05-22 JP JP2003500061A patent/JP4323309B2/ja not_active Expired - Fee Related
- 2002-05-22 AT AT08075527T patent/ATE506351T1/de active
- 2002-05-22 PL PL366993A patent/PL215305B1/pl unknown
- 2002-05-22 US US10/478,770 patent/US7241886B2/en not_active Expired - Lifetime
- 2002-05-22 CZ CZ20033203A patent/CZ303130B6/cs not_active IP Right Cessation
- 2002-05-22 WO PCT/GB2002/002356 patent/WO2002096881A1/fr not_active Ceased
- 2002-05-22 CA CA2448094A patent/CA2448094C/fr not_active Expired - Lifetime
- 2002-05-22 CA CA2750876A patent/CA2750876C/fr not_active Expired - Fee Related
- 2002-05-22 RU RU2003137224/04A patent/RU2311411C2/ru active
- 2002-05-22 DE DE60227517T patent/DE60227517D1/de not_active Expired - Lifetime
- 2002-05-24 AR ARP020101958A patent/AR035460A1/es not_active Application Discontinuation
2007
- 2007-06-01 RU RU2007120532/04A patent/RU2449992C2/ru not_active IP Right Cessation
- 2007-10-04 AU AU2007221834A patent/AU2007221834B2/en not_active Ceased
2008
- 2008-08-05 JP JP2008201613A patent/JP2009057376A/ja active Pending
- 2008-09-17 CY CY20081100998T patent/CY1108345T1/el unknown
2009
- 2009-03-09 JP JP2009054515A patent/JP5280252B2/ja not_active Expired - Fee Related
- 2009-08-28 LU LU91603C patent/LU91603I2/fr unknown
- 2009-10-19 CY CY2009017C patent/CY2009017I2/el unknown
2011
- 2011-05-27 CY CY20111100515T patent/CY1111492T1/el unknown

Also Published As

Publication number	Publication date
JP4323309B2 (ja)	2009-09-02
EP1958938B1 (fr)	2011-04-20
AU2002307863B8 (en)	2007-10-18
HUP0400296A2 (hu)	2004-08-30
WO2002096881A1 (fr)	2002-12-05
CZ20033203A3 (cs)	2004-06-16
ES2362688T3 (es)	2011-07-11
JP2009167194A (ja)	2009-07-30
ES2305299T3 (es)	2008-11-01
CN1511141B (zh)	2011-06-08
CA2448094C (fr)	2011-11-01
JP2009057376A (ja)	2009-03-19
CY1111492T1 (el)	2015-08-05
SI1399424T1 (sl)	2008-10-31
EP1399424B1 (fr)	2008-07-09
CN1511141A (zh)	2004-07-07
AU2007221834B2 (en)	2009-02-05
CY1108345T1 (el)	2012-01-25
PL215305B1 (pl)	2013-11-29
US20040158060A1 (en)	2004-08-12
ATE506351T1 (de)	2011-05-15
DK1958938T3 (da)	2011-07-25
DE60227517D1 (de)	2008-08-21
WO2002096881A8 (fr)	2003-02-27
EP1958938A2 (fr)	2008-08-20
DE60239842D1 (de)	2011-06-01
JP2004532263A (ja)	2004-10-21
KR100931916B1 (ko)	2009-12-15
ATE400560T1 (de)	2008-07-15
MXPA03010793A (es)	2004-07-01
AR035460A1 (es)	2004-05-26
PL366993A1 (en)	2005-02-07
AU2002307863B2 (en)	2007-09-27
CY2009017I1 (el)	2012-01-25
EP1958938A3 (fr)	2008-09-03
CZ303130B6 (cs)	2012-04-18
US7241886B2 (en)	2007-07-10
JP5280252B2 (ja)	2013-09-04
CN101172967A (zh)	2008-05-07
CA2750876A1 (fr)	2002-12-05
RU2311411C2 (ru)	2007-11-27
CA2750876C (fr)	2014-10-28
CY2009017I2 (el)	2012-01-25
BR0210019A (pt)	2004-08-10
HUP0400296A3 (en)	2008-03-28
CA2448094A1 (fr)	2002-12-05
EP1399424A1 (fr)	2004-03-24
GB0112812D0 (en)	2001-07-18
DK1399424T3 (da)	2008-09-08
RU2449992C2 (ru)	2012-05-10
KR20040030626A (ko)	2004-04-09
HU230019B1 (hu)	2015-05-28
AU2007221834A1 (en)	2007-10-25
EP1399424B8 (fr)	2008-10-01
RU2007120532A (ru)	2008-12-10
RU2003137224A (ru)	2005-05-27

Publication	Publication Date	Title
LU91603I2 (fr)	2009-10-28	Eslicarbazepine acetate (Zebinix - eslicarbazepineacetate) Composé: énantiomère S de la Licarbazepi ne
NO20042680L (no)	2004-06-25	Fremgangsmater for fremstilling av O-demetylvenflaxine
DK1451192T3 (da)	2011-04-04	Ny krystallinsk forbindelse
DE60217126D1 (de)	2007-02-08	Herstellung von aminopyrimidinverbindungen
EP1451156A4 (fr)	2005-05-25	Composes 4-aminoquinoleines
NO20034127L (no)	2003-11-06	Forbedring av aromainneholdende bestanddeler
NO329883B1 (no)	2011-01-17	Fremgangsmate for fremstilling av prostaglandiner og analoger derav og av mellomforbindelser, og forbindelser fremstilt derved
NO20034538D0 (no)	2003-10-09	Anvendelsen av enantiomer ren escitalopram
DK1385826T3 (da)	2007-04-30	Fremgangsmåde til fremstilling af (S)-(+)- og (R)-(-)-10,11-dihydro-10-hydroxy-5H-dibenz/b,f/azapin-5-carboxamid
NO20040027L (no)	2004-01-05	Fremgangsmate for fremstillingen av escitalopram
DE50213466D1 (de)	2009-05-28	Fungizide wirkstoffkombinationen
ITMI991658A0 (it)	1999-07-27	Procedimento per la preparazione di epossidi
NO20042667L (no)	2004-06-24	Fremgangsmate for fremstilling av escitalopram
PT1387923E (pt)	2006-09-29	Coroa de perfuracao.
EE200300442A (et)	2003-12-15	Meetod imidasoolühendite valmistamiseks
NO20052158L (no)	2005-05-02	Fremgangsmate for fremstilling av en benzimidazolforbindelse.
FI20011484L (fi)	2003-01-07	Menetelmä ulkokutsujen allokoimiseksi
ITMI20030018A1 (it)	2004-07-10	Procedimento per la preparazione di composti mono-
IT1338456B1 (it)	2007-03-12	Procedimento per la preparazione di alchiluree da o ,d-dimetil ditiocarbonato
FI20010892A0 (fi)	2001-04-27	Menetelmä ksylitolin valmistamiseksi
NO20052396D0 (no)	2005-05-13	Fremgangsmate for fremstilling av spirolactonforbindelser
DE50209082D1 (de)	2007-02-08	Zwischenverbindungen zur herstellung von spinosynen
NO20042116L (no)	2004-08-17	Avgiftning av oniumforbindelser
CL2004001156A1 (es)	2005-03-28	Procedimiento de preparacion de compuestos heterociclicos.
FI20012552A0 (fi)	2001-12-21	Metallikarbonaatin valmistusmenetelmä