ATE400560T1 - Verfahren zur herstellung von 10,11 dihydro 10 hydroxy 5h-dibenz/b,f/azepin-5-carbonsäureamid und 10,11 dihydro 10 oxo-5h-dibenz/b,f/azepin-5 carbonsäureamid - Google Patents

Verfahren zur herstellung von 10,11 dihydro 10 hydroxy 5h-dibenz/b,f/azepin-5-carbonsäureamid und 10,11 dihydro 10 oxo-5h-dibenz/b,f/azepin-5 carbonsäureamid

Info

Publication number: ATE400560T1
Authority: AT; Austria
Prior art keywords: dibenz; azepine; dihydro; acid amide; carbonic acid
Prior art date: 2001-05-25

Application number

AT02774050T

Other languages

English (en)

Inventor

David Learmonth

Original Assignee

Portela & Ca Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-05-25

Filing date

2002-05-22

Publication date

2008-07-15

2002-05-22 Application filed by Portela & Ca Sa filed Critical Portela & Ca Sa

2008-07-15 Application granted granted Critical

2008-07-15 Publication of ATE400560T1 publication Critical patent/ATE400560T1/de

Links

KXDHJXZQYSOELW-UHFFFAOYSA-N Carbamic acid Chemical compound NC(O)=O KXDHJXZQYSOELW-UHFFFAOYSA-N 0.000 title 1
XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical class [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Epoxy Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Catalysts (AREA)

AT02774050T 2001-05-25 2002-05-22 Verfahren zur herstellung von 10,11 dihydro 10 hydroxy 5h-dibenz/b,f/azepin-5-carbonsäureamid und 10,11 dihydro 10 oxo-5h-dibenz/b,f/azepin-5 carbonsäureamid ATE400560T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB0112812.3A GB0112812D0 (en)	2001-05-25	2001-05-25	Mthd for preparation of 10, 11-dihydro-10-hydroxy-5H-dibenz/B,F/azepine-5-c arboxamide and 10,11-dihydro-10-oxo-5H-dibenz/B,F/azepine-5-carb oxamide therefrom

Publications (1)

Publication Number	Publication Date
ATE400560T1 true ATE400560T1 (de)	2008-07-15

Family

ID=9915332

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT02774050T ATE400560T1 (de)	2001-05-25	2002-05-22	Verfahren zur herstellung von 10,11 dihydro 10 hydroxy 5h-dibenz/b,f/azepin-5-carbonsäureamid und 10,11 dihydro 10 oxo-5h-dibenz/b,f/azepin-5 carbonsäureamid
AT08075527T ATE506351T1 (de)	2001-05-25	2002-05-22	Verfahren zur herstellung von 10,11-dihydro-10- oxo-5h-dibenzoäb,füazepin-5-carboxamid

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT08075527T ATE506351T1 (de)	2001-05-25	2002-05-22	Verfahren zur herstellung von 10,11-dihydro-10- oxo-5h-dibenzoäb,füazepin-5-carboxamid

Country Status (23)

Country	Link
US (1)	US7241886B2 (de)
EP (2)	EP1399424B8 (de)
JP (3)	JP4323309B2 (de)
KR (1)	KR100931916B1 (de)
CN (2)	CN101172967A (de)
AR (1)	AR035460A1 (de)
AT (2)	ATE400560T1 (de)
AU (2)	AU2002307863B8 (de)
BR (1)	BR0210019A (de)
CA (2)	CA2448094C (de)
CY (3)	CY1108345T1 (de)
CZ (1)	CZ303130B6 (de)
DE (2)	DE60227517D1 (de)
DK (2)	DK1399424T3 (de)
ES (2)	ES2305299T3 (de)
GB (1)	GB0112812D0 (de)
HU (1)	HU230019B1 (de)
LU (1)	LU91603I2 (de)
MX (1)	MXPA03010793A (de)
PL (1)	PL215305B1 (de)
RU (2)	RU2311411C2 (de)
SI (1)	SI1399424T1 (de)
WO (1)	WO2002096881A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0303615D0 (en) *	2003-02-17	2003-03-19	Novartis Ag	Use of organic compounds
ITMI20042230A1 (it)	2004-11-19	2005-02-19	Farchemia Srl	Procedimento per la preparazione della 10,11-diidro-10 idrossi-5h-dibenz-b,f-azepin-5carbossiammide
ITMI20042291A1 (it) *	2004-11-26	2005-02-26	Farchema S R L	Procedimento per la preparazione della -s-piu-10,11-diidro-10-idrossi-5h-dibenz-b,f-azepin-5-carbossiammide
GB2422149A (en)	2005-01-14	2006-07-19	Portela & Ca Sa	Process for the preparation of 10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
US20060252745A1 (en) *	2005-05-06	2006-11-09	Almeida Jose L D	Methods of preparing pharmaceutical compositions comprising eslicarbazepine acetate and methods of use
GB0515690D0 (en)	2005-07-29	2005-09-07	Portela & Ca Sa	Asymmetric catalytic reduction
GB0517740D0 (en) *	2005-08-31	2005-10-12	Novartis Ag	Organic compounds
GB0700773D0 (en)	2007-01-15	2007-02-21	Portela & Ca Sa	Drug therapies
US8372431B2 (en) *	2007-10-26	2013-02-12	Bial-Portela & C.A., S.A.	Pharmaceutical composition comprising licarbazepine acetate
UA106384C2 (ru)	2009-07-27	2014-08-26	БИАЛ-ПОРТЕЛА энд КА., С.А.	ПРИМЕНЕНИЕ ПРОИЗВОДНЫХ 5H-ДИБЕНЗ/б,ф/АЗЕПИН-5-КАРБОКСАМИДА ДЛЯ ЛЕЧЕНИЯ ФИБРОМИАЛГИИ
WO2013008194A2 (en)	2011-07-13	2013-01-17	Ranbaxy Laboratories Limited	Process for the preparation and purification of eslicarbazepine acetate and intermediates thereof
US20150232426A1 (en)	2012-09-26	2015-08-20	Ranbaxy Laboratories Limited	Process for the preparation of oxcarbazepine and its use as intermediate in the preparation of eslicarbazepine acetate
US12492423B2 (en)	2015-09-16	2025-12-09	PetaOmics, Inc.	Methods and compositions for genomic target enrichment and selective DNA sequencing
HK1257030A1 (zh)	2015-09-16	2019-10-11	PetaOmics, Inc.	用於基因组目标富集和选择性dna测序的方法和组合物
CN111943347B (zh) *	2020-07-16	2022-08-30	同济大学	一种铜离子活化过氧乙酸去除废水中卡马西平的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5439390B2 (de) *	1971-09-30	1979-11-27
BE789320A (fr) *	1971-09-30	1973-03-27	Takeda Chemical Industries Ltd	Derives de dibenzoxirenazepine
CH633271A5 (en) *	1978-04-18	1982-11-30	Ciba Geigy Ag	Process for the rearrangement of 10,11-epoxy-10,11-dihydro-5H-dibenz[b,f]azepines to give 10-oxo-10,11-dihydro-5H-dibenz(b,f)azepines
CH642950A5 (en) *	1979-10-30	1984-05-15	Ciba Geigy Ag	Process for the preparation of 10-oxo-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide
IT1272897B (it) *	1995-01-13	1997-07-01	I F C Iniziative Finanziaarie	Processo per la produzione di 10-oxo-10,11-diidro-sh- -dibenz(b,f) azepin-5-carbossiammide
PT101732B (pt) *	1995-06-30	1997-12-31	Portela & Ca Sa	Novas di-hidrodibenzo<b,f>azepinas substituidas processo para a sua preparacao composicoes farmaceuticas que as contem e utilizacao dos novos compostos na preparacao de composicoes farmaceuticas empregues em doencas do sistema nervoso
PT101876B (pt) *	1996-05-27	1999-09-30	Portela & Ca Sa	Novos derivados de 10,11-di-hidro-10-oxo-5h-dibenzo(b,f)azepina-5-carboxamida
AT408224B (de) *	1999-03-15	2001-09-25	Dsm Fine Chem Austria Gmbh	Verfahren zur herstellung von oxcarbazepin

2001
- 2001-05-25 GB GBGB0112812.3A patent/GB0112812D0/en not_active Ceased
2002
- 2002-05-22 KR KR1020037015323A patent/KR100931916B1/ko not_active Expired - Fee Related
- 2002-05-22 PL PL366993A patent/PL215305B1/pl unknown
- 2002-05-22 EP EP02774050A patent/EP1399424B8/de not_active Expired - Lifetime
- 2002-05-22 DK DK02774050T patent/DK1399424T3/da active
- 2002-05-22 BR BR0210019-3A patent/BR0210019A/pt active Search and Examination
- 2002-05-22 CN CNA2007101939981A patent/CN101172967A/zh active Pending
- 2002-05-22 CA CA2448094A patent/CA2448094C/en not_active Expired - Lifetime
- 2002-05-22 AT AT02774050T patent/ATE400560T1/de active
- 2002-05-22 CN CN028105915A patent/CN1511141B/zh not_active Expired - Fee Related
- 2002-05-22 EP EP08075527A patent/EP1958938B1/de not_active Expired - Lifetime
- 2002-05-22 AT AT08075527T patent/ATE506351T1/de active
- 2002-05-22 ES ES02774050T patent/ES2305299T3/es not_active Expired - Lifetime
- 2002-05-22 CZ CZ20033203A patent/CZ303130B6/cs not_active IP Right Cessation
- 2002-05-22 DK DK08075527.5T patent/DK1958938T3/da active
- 2002-05-22 DE DE60227517T patent/DE60227517D1/de not_active Expired - Lifetime
- 2002-05-22 ES ES08075527T patent/ES2362688T3/es not_active Expired - Lifetime
- 2002-05-22 CA CA2750876A patent/CA2750876C/en not_active Expired - Fee Related
- 2002-05-22 RU RU2003137224/04A patent/RU2311411C2/ru active
- 2002-05-22 DE DE60239842T patent/DE60239842D1/de not_active Expired - Lifetime
- 2002-05-22 WO PCT/GB2002/002356 patent/WO2002096881A1/en not_active Ceased
- 2002-05-22 JP JP2003500061A patent/JP4323309B2/ja not_active Expired - Fee Related
- 2002-05-22 HU HU0400296A patent/HU230019B1/hu unknown
- 2002-05-22 US US10/478,770 patent/US7241886B2/en not_active Expired - Lifetime
- 2002-05-22 SI SI200230717T patent/SI1399424T1/sl unknown
- 2002-05-22 AU AU2002307863A patent/AU2002307863B8/en not_active Ceased
- 2002-05-22 MX MXPA03010793A patent/MXPA03010793A/es active IP Right Grant
- 2002-05-24 AR ARP020101958A patent/AR035460A1/es not_active Application Discontinuation
2007
- 2007-06-01 RU RU2007120532/04A patent/RU2449992C2/ru not_active IP Right Cessation
- 2007-10-04 AU AU2007221834A patent/AU2007221834B2/en not_active Ceased
2008
- 2008-08-05 JP JP2008201613A patent/JP2009057376A/ja active Pending
- 2008-09-17 CY CY20081100998T patent/CY1108345T1/el unknown
2009
- 2009-03-09 JP JP2009054515A patent/JP5280252B2/ja not_active Expired - Fee Related
- 2009-08-28 LU LU91603C patent/LU91603I2/fr unknown
- 2009-10-19 CY CY2009017C patent/CY2009017I1/el unknown
2011
- 2011-05-27 CY CY20111100515T patent/CY1111492T1/el unknown

Also Published As

Publication number	Publication date
AU2007221834A1 (en)	2007-10-25
KR100931916B1 (ko)	2009-12-15
DK1958938T3 (da)	2011-07-25
EP1958938A2 (de)	2008-08-20
CZ303130B6 (cs)	2012-04-18
JP2004532263A (ja)	2004-10-21
HUP0400296A2 (hu)	2004-08-30
WO2002096881A8 (en)	2003-02-27
EP1958938B1 (de)	2011-04-20
AU2002307863B2 (en)	2007-09-27
CA2750876C (en)	2014-10-28
CY1108345T1 (el)	2012-01-25
CY2009017I2 (el)	2012-01-25
DE60227517D1 (de)	2008-08-21
RU2311411C2 (ru)	2007-11-27
JP2009167194A (ja)	2009-07-30
SI1399424T1 (sl)	2008-10-31
PL366993A1 (en)	2005-02-07
HU230019B1 (hu)	2015-05-28
WO2002096881A1 (en)	2002-12-05
AU2002307863B8 (en)	2007-10-18
EP1399424A1 (de)	2004-03-24
MXPA03010793A (es)	2004-07-01
PL215305B1 (pl)	2013-11-29
RU2007120532A (ru)	2008-12-10
LU91603I2 (fr)	2009-10-28
RU2003137224A (ru)	2005-05-27
JP2009057376A (ja)	2009-03-19
AR035460A1 (es)	2004-05-26
EP1958938A3 (de)	2008-09-03
ES2362688T3 (es)	2011-07-11
CA2448094C (en)	2011-11-01
CN101172967A (zh)	2008-05-07
CY1111492T1 (el)	2015-08-05
CA2750876A1 (en)	2002-12-05
CY2009017I1 (el)	2012-01-25
DE60239842D1 (de)	2011-06-01
AU2007221834B2 (en)	2009-02-05
ES2305299T3 (es)	2008-11-01
CN1511141B (zh)	2011-06-08
EP1399424B1 (de)	2008-07-09
CN1511141A (zh)	2004-07-07
JP4323309B2 (ja)	2009-09-02
DK1399424T3 (da)	2008-09-08
ATE506351T1 (de)	2011-05-15
BR0210019A (pt)	2004-08-10
JP5280252B2 (ja)	2013-09-04
US7241886B2 (en)	2007-07-10
RU2449992C2 (ru)	2012-05-10
KR20040030626A (ko)	2004-04-09
CZ20033203A3 (cs)	2004-06-16
CA2448094A1 (en)	2002-12-05
EP1399424B8 (de)	2008-10-01
US20040158060A1 (en)	2004-08-12
GB0112812D0 (en)	2001-07-18
HUP0400296A3 (en)	2008-03-28

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2009-04-15

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