LUC00296I2 - - Google Patents

Info

Publication number
LUC00296I2
LUC00296I2 LU00296C LUC00296C LUC00296I2 LU C00296 I2 LUC00296 I2 LU C00296I2 LU 00296 C LU00296 C LU 00296C LU C00296 C LUC00296 C LU C00296C LU C00296 I2 LUC00296 I2 LU C00296I2
Authority
LU
Luxembourg
Application number
LU00296C
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55315708&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LUC00296(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of LUC00296I2 publication Critical patent/LUC00296I2/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/645—Secretins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
LU00296C 2015-01-09 2023-02-03 LUC00296I2 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562101488P 2015-01-09 2015-01-09

Publications (1)

Publication Number Publication Date
LUC00296I2 true LUC00296I2 (fr) 2025-09-22

Family

ID=55315708

Family Applications (1)

Application Number Title Priority Date Filing Date
LU00296C LUC00296I2 (fr) 2015-01-09 2023-02-03

Country Status (46)

Country Link
US (1) US9474780B2 (fr)
EP (2) EP3597662A1 (fr)
JP (3) JP6219534B2 (fr)
KR (5) KR101957620B1 (fr)
CN (2) CN112608377B (fr)
AR (2) AR103242A1 (fr)
AU (1) AU2016205435B2 (fr)
CA (1) CA2973352C (fr)
CL (1) CL2017001760A1 (fr)
CO (1) CO2017006737A2 (fr)
CR (1) CR20170310A (fr)
CY (2) CY1122028T1 (fr)
DK (1) DK3242887T3 (fr)
DO (1) DOP2017000153A (fr)
EA (3) EA202090392A3 (fr)
EC (1) ECSP17043648A (fr)
ES (1) ES2747928T3 (fr)
FI (1) FIC20230005I1 (fr)
FR (1) FR23C1006I2 (fr)
HR (1) HRP20191614T1 (fr)
HU (2) HUE045860T2 (fr)
IL (4) IL320236A (fr)
JO (2) JO3575B1 (fr)
LT (2) LT3242887T (fr)
LU (1) LUC00296I2 (fr)
MA (2) MA50422A (fr)
MD (1) MD3242887T2 (fr)
ME (1) ME03494B (fr)
MX (2) MX382753B (fr)
MY (1) MY193616A (fr)
NL (1) NL301217I2 (fr)
NO (1) NO2023005I1 (fr)
NZ (3) NZ771043A (fr)
PE (1) PE20170954A1 (fr)
PH (1) PH12017501252B1 (fr)
PL (1) PL3242887T3 (fr)
PT (1) PT3242887T (fr)
RS (1) RS59146B1 (fr)
SG (1) SG11201705603YA (fr)
SI (1) SI3242887T1 (fr)
SV (1) SV2017005453A (fr)
TN (1) TN2017000198A1 (fr)
TW (1) TWI582109B (fr)
UA (1) UA118239C2 (fr)
WO (1) WO2016111971A1 (fr)
ZA (1) ZA201703930B (fr)

Families Citing this family (113)

* Cited by examiner, † Cited by third party
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AU2014364589B2 (en) 2013-12-18 2020-02-27 The California Institute For Biomedical Research Modified therapeutic agents, stapled peptide lipid conjugates, and compositions thereof
TWI622596B (zh) 2015-10-26 2018-05-01 美國禮來大藥廠 升糖素受體促效劑
US11285180B2 (en) 2016-12-06 2022-03-29 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods of enhancing the potency of incretin-based drugs in subjects in need thereof
JOP20190211A1 (ar) 2017-03-31 2019-09-15 Takeda Pharmaceuticals Co ببتيد منشط لمستقبل gip
WO2018213151A1 (fr) * 2017-05-18 2018-11-22 Merck Sharp & Dohme Corp. Formulation pharmaceutique comprenant des conjugués d'incrétine-insuline
HRP20240485T1 (hr) 2017-08-24 2024-07-05 Novo Nordisk A/S Pripravci glp-1 i njihova upotreba
TWI767095B (zh) * 2017-12-21 2022-06-11 美商美國禮來大藥廠 腸促胰島素(incretin)類似物及其用途
TWI912614B (zh) * 2017-12-21 2026-01-21 美商美國禮來大藥廠 腸促胰島素(incretin)類似物及其用途
WO2019140030A1 (fr) 2018-01-12 2019-07-18 Eli Lilly And Company Polythérapie
PL3746111T3 (pl) 2018-02-02 2024-01-15 Novo Nordisk A/S Stałe kompozycje zawierające agonistę glp-1 i sól kwasu n-(8-(2- hydroksybenzoilo)amino kaprylowego i substancję poślizgową
ES3053674T3 (en) 2018-03-22 2026-01-23 Viking Therapeutics Inc Crystalline forms and methods of producing crystalline forms of a compound
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TWI705820B (zh) * 2018-06-22 2020-10-01 美商美國禮來大藥廠 Gip/glp1促效劑組合物
CN112469731B (zh) * 2018-07-23 2024-11-29 伊莱利利公司 Gip/glp1共激动剂化合物
CN120754229A (zh) * 2018-07-23 2025-10-10 伊莱利利公司 使用gip/glp1共激动剂用于治疗的方法
EP3826662B9 (fr) * 2018-07-23 2025-02-19 Eli Lilly and Company Procédé d'utilisation d'un co-agoniste de gip/glp1 contre le diabète
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WO2020117962A1 (fr) 2018-12-05 2020-06-11 Viking Therapeutics, Inc. Compositions pour le traitement de la fibrose et de l'inflammation
TWI799680B (zh) * 2019-01-29 2023-04-21 美商美國禮來大藥廠 製備gip/glp1雙重促效劑之方法
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KR20220020879A (ko) 2019-06-12 2022-02-21 에스크진 파마, 아이엔씨. 새로운 il-15 프로드럭 및 이를 사용하는 방법
TWI764209B (zh) 2019-08-01 2022-05-11 美商美國禮來大藥廠 Gipr促效劑化合物
MX2022002115A (es) 2019-08-19 2022-03-17 Lilly Co Eli Metodos para preparar analogos de incretina.
WO2021066600A1 (fr) 2019-10-04 2021-04-08 한미약품 주식회사 Glucagon, composition comprenant un agoniste double du récepteur de glp-1 et du récepteur de gip et utilisation thérapeutique associée
CN110684082B (zh) * 2019-10-08 2021-12-10 江苏诺泰澳赛诺生物制药股份有限公司 Gip和glp-1双激动多肽化合物及药学上可接受的盐与用途
AU2020397917A1 (en) 2019-12-04 2022-06-23 The Scripps Research Institute GLP2 receptor agonists and methods of use
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WO2021142471A1 (fr) 2020-01-11 2021-07-15 AskGene Pharma, Inc. Nouvelles cytokines masquées et leurs procédés d'utilisation
WO2021150673A1 (fr) 2020-01-23 2021-07-29 Eli Lilly And Company Composés co-agonistes de gip/glp1
TW202228762A (zh) * 2020-01-30 2022-08-01 美商美國禮來大藥廠 提派肽(tirzepatide)之治療用途
CN111253475B (zh) * 2020-02-18 2021-03-09 江苏诺泰澳赛诺生物制药股份有限公司 Glp-1激动多肽化合物及其盐与合成方法及用途
CN115884982A (zh) 2020-03-06 2023-03-31 赛诺菲 作为选择性gip受体激动剂的肽
CN113493503B (zh) * 2020-04-08 2022-08-05 浙江道尔生物科技有限公司 一种肠促胰岛素类似物及其制备方法和用途
TW202216746A (zh) * 2020-06-22 2022-05-01 印度商太陽製藥工業有限公司 長效型ｇｌｐ－１／ｇｉｐ雙重促效劑
CN116113429A (zh) * 2020-07-06 2023-05-12 鸿绪生物医药科技（北京）有限公司 新型多肽及其治疗用途
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MX2023000303A (es) * 2020-07-22 2023-02-09 Novo Nordisk As Coagonistas de los receptores del peptido 1 similar al glucagon (glp-1) y del polipeptido insulinotropico dependiente de glucosa (gip) adecuados para el suministro oral.
CN114729060B (zh) * 2020-09-30 2022-11-25 北京质肽生物医药科技有限公司 多肽缀合物和使用方法
WO2022080986A1 (fr) 2020-10-16 2022-04-21 한미약품 주식회사 Agoniste double de glp-1/gip, conjugué à action prolongée de celui-ci, et composition pharmaceutique le comprenant
CN116171164A (zh) 2020-10-17 2023-05-26 太阳医药工业有限公司 Glp-1/gip双重激动剂
EP4257597A4 (fr) * 2020-12-02 2025-04-02 Dongbao Purple Star (Hangzhou) Biopharmaceutical Co., Ltd. Composés polypeptidiques modifiés par lactame
WO2022159395A1 (fr) 2021-01-20 2022-07-28 Viking Therapeutics, Inc. Compositions et procédés pour le traitement de troubles métaboliques et hépatiques
WO2022177742A2 (fr) 2021-02-17 2022-08-25 Eli Lilly And Company Méthodes thérapeutiques au tirzépatide
JP2024508745A (ja) * 2021-02-17 2024-02-28 イーライ リリー アンド カンパニー Ｇｉｐ／ｇｌｐ１デュアルアゴニスト治療方法
US12215133B2 (en) 2021-03-25 2025-02-04 Brightgene Bio-Medical Technology Co., Ltd. GIP and GLP-1 dual receptor agonist, pharmaceutical composition, and use
CN115124602B (zh) * 2021-03-25 2024-01-26 博瑞生物医药（苏州）股份有限公司 Gip和glp-1的双受体激动剂、药物组合物及用途
CN117642153A (zh) 2021-05-07 2024-03-01 伊莱利利公司 易蚀片剂
IL308392A (en) 2021-05-13 2024-01-01 Carmot Therapeutics Inc G protein-coupled receptor modulators
CN118307645A (zh) * 2021-05-28 2024-07-09 广东众生睿创生物科技有限公司 多肽的制备及其应用
WO2022253202A1 (fr) * 2021-06-01 2022-12-08 南京知和医药科技有限公司 Dérivé polypeptidique ayant un effet d'activation à double cible de glp-1r et de gipr, procédé de préparation associé et son utilisation
MX2023014771A (es) 2021-06-09 2024-03-19 Scripps Research Inst Conjugados peptidicos duales gip/glp-1 de accion prolongada y metodos de uso.
WO2022262825A1 (fr) * 2021-06-18 2022-12-22 南京明德新药研发有限公司 Composé polypeptidique contenant un pont lactame
EP4399224A1 (fr) 2021-09-06 2024-07-17 Sanofi Nouveaux peptides utilisés en tant qu'agonistes puissants et sélectifs du récepteur de gip
MX2024003236A (es) * 2021-09-15 2024-06-19 Viking Therapeutics Inc Composiciones y metodos para el tratamiento de trastornos metabolicos y hepaticos.
US20250000948A1 (en) 2021-11-15 2025-01-02 Adocia Solid compositions comprising a peptide or a protein and an acylated amino acid
EP4180060A1 (fr) 2021-11-15 2023-05-17 Adocia Compositions solides comportant un peptide ou une protéine et un acide aminé acylé
EP4299057A1 (fr) 2022-06-30 2024-01-03 Adocia Compositions solides comportant un peptide ou une protéine et un acide aminé acylé
US20250019410A1 (en) 2021-11-22 2025-01-16 Sun Pharmaceutical Industries Ltd. Process for the preparation of tirzepatide or pharmaceutically acceptable salt thereof
TW202330584A (zh) 2022-01-20 2023-08-01 丹麥商諾佛 儂迪克股份有限公司 前藥及其用途
CN118843640A (zh) * 2022-04-07 2024-10-25 广东众生睿创生物科技有限公司 多肽在制备治疗和/或预防糖尿病及肥胖症及其相关疾病药物中的制药用途
CN116947978A (zh) * 2022-04-19 2023-10-27 北京惠之衡生物科技有限公司 一种glp-1和gip受体共激动多肽衍生物及其盐和制剂
KR20250029908A (ko) 2022-06-30 2025-03-05 일라이 릴리 앤드 캄파니 티르제파티드 조성물 및 용도
EP4299052A1 (fr) 2022-06-30 2024-01-03 Adocia Compositions solides comportant un peptide ou une protéine et un agent améliorant la perméation
EP4299071A1 (fr) 2022-07-01 2024-01-03 Adocia Compositions comprenant un peptide ou une protéine et un acide aminé acylé
UY40349A (es) * 2022-07-13 2024-01-31 Hangzhou Zhongmeihuadong Pharmaceutical Co Ltd Agonista dual de glp-1/gip, método de preparación y uso del mismo
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JP2025531200A (ja) 2022-09-15 2025-09-19 イーライ リリー アンド カンパニー Ｇｉｐ及びｇｌｐ－１二重アゴニスト化合物
JP2025531387A (ja) * 2022-09-23 2025-09-19 ブライトジーン プライベート リミティド Ｇｌｐ－１とｇｉｐの二重受容体アゴニスト医薬組成物及びその用途
JP2025533109A (ja) 2022-10-05 2025-10-03 イーライ リリー アンド カンパニー インクレチン合成のためのペプチド
KR102942046B1 (ko) * 2022-10-19 2026-03-24 일라이 릴리 앤드 캄파니 보존된 gip/glp 효능제 조성물
CN117756913B (zh) * 2022-11-07 2025-05-09 内蒙古博睿精创科技有限公司 一种新型长效多肽化合物、组合物及其应用
KR20250110330A (ko) 2022-11-21 2025-07-18 일라이 릴리 앤드 캄파니 Gip/glp1 이중 효능제의 제조 방법
WO2024128882A1 (fr) 2022-12-16 2024-06-20 주식회사 펩트론 Microsphères à libération prolongée comprenant un agoniste du récepteur glp-1 ou un sel pharmaceutiquement acceptable de celui-ci et leur utilisation
WO2024145638A2 (fr) 2022-12-29 2024-07-04 Eli Lilly And Company Procédés et intermédiaires pour la préparation de tirzépatide
JP2026502943A (ja) 2022-12-30 2026-01-27 アルギファルマ エーエス 経口投与されるポリペプチド治療剤の全身バイオアベイラビリティを高める組成物および方法
PE20252287A1 (es) 2023-01-31 2025-09-18 Lilly Co Eli Agonistas del trirreceptor gip/glp1/gcg y usos de estos
WO2024165571A2 (fr) 2023-02-06 2024-08-15 E-Therapeutics Plc Inhibiteurs d'expression et/ou de fonction
AU2024235143A1 (en) * 2023-03-15 2025-09-11 Viking Therapeutics, Inc. Pharmaceutical compositions and methods for the treatment of metabolic and liver disorders
CN118684758A (zh) * 2023-03-23 2024-09-24 上海民为生物技术有限公司 肠促胰岛素类似物及其应用
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