LV10055B - Prolonged release preparation and polymers thereof - Google Patents

Prolonged release preparation and polymers thereof Download PDF

Info

Publication number: LV10055B
Authority: LV; Latvia
Prior art keywords: acid; copolymer; lactic acid; polymer; preparation
Prior art date: 1990-10-16

Application number

LVP-92-573A

Other languages

English (en)

Latvian (lv)

Other versions

LV10055A (lv

Inventor

Minoru Yamada

Seiko Ishiguro

Yasuaki Ogawa

Original Assignee

Takeda Chemical Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-10-16

Filing date

1992-12-30

Publication date

1995-02-20

1992-12-30 Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd

1994-05-10 Publication of LV10055A publication Critical patent/LV10055A/xx

1995-02-20 Publication of LV10055B publication Critical patent/LV10055B/lv

Links

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KDQAABAKXDWYSZ-PNYVAJAMSA-N vinblastine sulfate Chemical compound OS(O)(=O)=O.C([C@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](OC(C)=O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(=O)OC)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1NC1=CC=CC=C21 KDQAABAKXDWYSZ-PNYVAJAMSA-N 0.000 description 1
229960004982 vinblastine sulfate Drugs 0.000 description 1
AQTQHPDCURKLKT-JKDPCDLQSA-N vincristine sulfate Chemical compound OS(O)(=O)=O.C([C@@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](OC(C)=O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(=O)OC)N3C=O)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1NC1=CC=CC=C21 AQTQHPDCURKLKT-JKDPCDLQSA-N 0.000 description 1
229960002110 vincristine sulfate Drugs 0.000 description 1
239000007762 w/o emulsion Substances 0.000 description 1
239000008096 xylene Substances 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/745—Polymers of hydrocarbons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
- C08L67/04—Polyesters derived from hydroxycarboxylic acids, e.g. lactones

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Organic Chemistry (AREA)
Polymers & Plastics (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Compositions Of Macromolecular Compounds (AREA)
Polyesters Or Polycarbonates (AREA)
Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

LVP-92-573A 1990-10-16 1992-12-30 Prolonged release preparation and polymers thereof LV10055B (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP27803790		1990-10-16
JP21704591		1991-08-28

Publications (2)

Publication Number	Publication Date
LV10055A LV10055A (lv)	1994-05-10
LV10055B true LV10055B (en)	1995-02-20

Family

ID=26521778

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LVP-92-573A LV10055B (en)	1990-10-16	1992-12-30	Prolonged release preparation and polymers thereof

Country Status (24)

Country	Link
US (1)	US5304377A (fr)
EP (1)	EP0481732B1 (fr)
JP (1)	JP3196035B2 (fr)
KR (1)	KR100199119B1 (fr)
CN (2)	CN1043189C (fr)
AT (1)	ATE119035T1 (fr)
AU (1)	AU644019B2 (fr)
CA (1)	CA2053468C (fr)
DE (1)	DE69107773T2 (fr)
DK (1)	DK0481732T3 (fr)
EE (1)	EE02958B1 (fr)
ES (1)	ES2069221T3 (fr)
FI (1)	FI101454B1 (fr)
GE (1)	GEP19981287B (fr)
IE (1)	IE66705B1 (fr)
LT (1)	LT3277B (fr)
LV (1)	LV10055B (fr)
MX (1)	MX9101595A (fr)
NO (1)	NO302481B1 (fr)
NZ (1)	NZ240214A (fr)
PT (1)	PT99236B (fr)
RU (1)	RU2103005C1 (fr)
UA (1)	UA27707C2 (fr)
ZA (1)	ZA918168B (fr)

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JPH0725689B2 (ja) *	1986-10-07	1995-03-22	中外製薬株式会社	顆粒球コロニ−刺激因子を含有する徐放性製剤
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1991
- 1991-10-14 ZA ZA918168A patent/ZA918168B/xx unknown
- 1991-10-14 NO NO914032A patent/NO302481B1/no not_active IP Right Cessation
- 1991-10-14 NZ NZ240214A patent/NZ240214A/xx unknown
- 1991-10-15 RU SU5010042A patent/RU2103005C1/ru active
- 1991-10-15 AT AT91309490T patent/ATE119035T1/de not_active IP Right Cessation
- 1991-10-15 AU AU85864/91A patent/AU644019B2/en not_active Ceased
- 1991-10-15 CA CA002053468A patent/CA2053468C/fr not_active Expired - Fee Related
- 1991-10-15 UA UA5010042A patent/UA27707C2/uk unknown
- 1991-10-15 DK DK91309490.0T patent/DK0481732T3/da active
- 1991-10-15 FI FI914865A patent/FI101454B1/fi active
- 1991-10-15 ES ES91309490T patent/ES2069221T3/es not_active Expired - Lifetime
- 1991-10-15 MX MX9101595A patent/MX9101595A/es not_active IP Right Cessation
- 1991-10-15 EP EP91309490A patent/EP0481732B1/fr not_active Expired - Lifetime
- 1991-10-15 PT PT99236A patent/PT99236B/pt not_active IP Right Cessation
- 1991-10-15 DE DE69107773T patent/DE69107773T2/de not_active Expired - Lifetime
- 1991-10-16 IE IE362491A patent/IE66705B1/en not_active IP Right Cessation
- 1991-10-16 JP JP26792991A patent/JP3196035B2/ja not_active Expired - Fee Related
- 1991-10-16 KR KR1019910018235A patent/KR100199119B1/ko not_active Expired - Fee Related
- 1991-10-16 CN CN91109723A patent/CN1043189C/zh not_active Expired - Fee Related
1992
- 1992-12-07 US US07/986,299 patent/US5304377A/en not_active Expired - Lifetime
- 1992-12-30 LV LVP-92-573A patent/LV10055B/lv unknown
1993
- 1993-03-11 GE GEAP1993605A patent/GEP19981287B/en unknown
- 1993-03-19 LT LTIP442A patent/LT3277B/lt not_active IP Right Cessation
1994
- 1994-11-17 EE EE9400413A patent/EE02958B1/xx unknown
1995
- 1995-03-10 CN CN95102413A patent/CN1057670C/zh not_active Expired - Fee Related

Also Published As

Publication number	Publication date
RU2103005C1 (ru)	1998-01-27
CA2053468C (fr)	2002-07-09
ES2069221T3 (es)	1995-05-01
ATE119035T1 (de)	1995-03-15
NZ240214A (en)	1993-02-25
CN1060851A (zh)	1992-05-06
KR100199119B1 (ko)	1999-06-15
US5304377A (en)	1994-04-19
DE69107773T2 (de)	1995-06-29
PT99236B (pt)	1999-04-30
FI914865A0 (fi)	1991-10-15
AU644019B2 (en)	1993-12-02
ZA918168B (en)	1993-04-14
NO914032L (no)	1992-04-21
UA27707C2 (uk)	2000-10-16
DK0481732T3 (da)	1995-05-22
GEP19981287B (en)	1998-09-01
JPH05112468A (ja)	1993-05-07
IE913624A1 (en)	1992-04-22
PT99236A (pt)	1992-09-30
IE66705B1 (en)	1996-01-24
LV10055A (lv)	1994-05-10
CN1057670C (zh)	2000-10-25
FI101454B (fi)	1998-06-30
EE02958B1 (et)	1997-02-17
NO914032D0 (no)	1991-10-14
EP0481732A1 (fr)	1992-04-22
FI914865L (fi)	1992-04-17
FI101454B1 (fi)	1998-06-30
AU8586491A (en)	1992-04-30
CN1043189C (zh)	1999-05-05
JP3196035B2 (ja)	2001-08-06
NO302481B1 (no)	1998-03-09
LTIP442A (en)	1994-11-25
EP0481732B1 (fr)	1995-03-01
CN1116212A (zh)	1996-02-07
KR920007632A (ko)	1992-05-27
DE69107773D1 (de)	1995-04-06
CA2053468A1 (fr)	1992-04-17
LT3277B (en)	1995-05-25
MX9101595A (es)	1992-06-05

Publication	Publication Date	Title
LV10055B (en)	1995-02-20	Prolonged release preparation and polymers thereof
EP0145240B1 (fr)	1989-04-19	Méthode de préparation de microcapsules
JP3277342B2 (ja)	2002-04-22	徐放性マイクロカプセルの製造法
KR100409413B1 (ko)	2004-04-30	서방성제제의제조방법
EP0535937B2 (fr)	2008-05-21	Préparation à base de microparticules à libération prolongée et production de celle-ci
RU2098121C1 (ru)	1997-12-10	Микрокапсула для длительного высвобождения физиологически активного пептида
KR920007831B1 (ko)	1992-09-18	지효성(持효性)미크로 캡슐의 제조방법
US6419961B1 (en)	2002-07-16	Sustained release microcapsules of a bioactive substance and a biodegradable polymer
CA2316159C (fr)	2008-04-29	Microcapsules a liberation lente
EP0582459B1 (fr)	1998-01-07	Production de microcapsules de médicaments solubles dans l'eau
EP1022020A2 (fr)	2000-07-26	Préparation à libération prolongée
JPS62201816A (ja)	1987-09-05	マイクロカプセルの製造法
JPH08151321A (ja)	1996-06-11	徐放剤
JP3902272B2 (ja)	2007-04-04	徐放性製剤の製造法