MA23818A1 - Variants de subtilisine carlsberg ayant une absorption reduite et une hydrolyse accrue - Google Patents

Variants de subtilisine carlsberg ayant une absorption reduite et une hydrolyse accrue

Info

Publication number
MA23818A1
MA23818A1 MA24175A MA24175A MA23818A1 MA 23818 A1 MA23818 A1 MA 23818A1 MA 24175 A MA24175 A MA 24175A MA 24175 A MA24175 A MA 24175A MA 23818 A1 MA23818 A1 MA 23818A1
Authority
MA
Morocco
Prior art keywords
subtilin
carlsberg
variants
reduced absorption
increased hydrolysis
Prior art date
Application number
MA24175A
Other languages
English (en)
Inventor
Nelton Rubingh Donn
Brode Phf Iii
Lee Barnett Robby
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of MA23818A1 publication Critical patent/MA23818A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/0005—Other compounding ingredients characterised by their effect
    • C11D3/0078—Compositions for cleaning contact lenses, spectacles or lenses
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Birds (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Detergent Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
MA24175A 1995-03-08 1996-03-07 Variants de subtilisine carlsberg ayant une absorption reduite et une hydrolyse accrue MA23818A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/400,698 US6455295B1 (en) 1995-03-08 1995-03-08 Subtilisin Carlsberg variants having decreased adsorption and increased hydrolysis

Publications (1)

Publication Number Publication Date
MA23818A1 true MA23818A1 (fr) 1996-10-01

Family

ID=23584644

Family Applications (1)

Application Number Title Priority Date Filing Date
MA24175A MA23818A1 (fr) 1995-03-08 1996-03-07 Variants de subtilisine carlsberg ayant une absorption reduite et une hydrolyse accrue

Country Status (14)

Country Link
US (1) US6455295B1 (fr)
EP (1) EP0813596A2 (fr)
JP (1) JPH11501812A (fr)
CN (1) CN1183119A (fr)
AU (1) AU4868896A (fr)
BR (1) BR9607356A (fr)
CA (1) CA2214348C (fr)
CZ (1) CZ279397A3 (fr)
HU (1) HUP9800765A3 (fr)
IL (1) IL117266A0 (fr)
MA (1) MA23818A1 (fr)
MX (1) MX9706851A (fr)
WO (1) WO1996028566A2 (fr)
ZA (1) ZA961631B (fr)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6682924B1 (en) * 1995-05-05 2004-01-27 Novozymes A/S Protease variants and compositions
BR9712878A (pt) * 1996-11-04 2000-02-01 Novo Nordisk As Variante de enzima subtilase, processos para a identificação de uma variante de protease apresentando estabilidade autoproteolìtica e paraq a produção de uma enzima subtilase mutante e de uma variante de subtilase, sequência de dna, vetor, célula hospedeira microbiana, composição e uso de uma variante de subtilase.
JPH10204500A (ja) * 1997-01-20 1998-08-04 Soft Kyukyu Corp:Kk 発泡錠剤洗浄剤
EP0913458B1 (fr) * 1997-10-22 2004-06-16 The Procter & Gamble Company Compositions détergentes liquide pour surfaces dures
AR015977A1 (es) 1997-10-23 2001-05-30 Genencor Int Variantes de proteasa multiplemente substituida con carga neta alterada para su empleo en detergentes
ES2368718T3 (es) * 1997-10-23 2011-11-21 Danisco Us Inc. Variantes de subtilisina con múltiples sustituciones.
CA2310454C (fr) 1997-11-21 2012-01-24 Novo Nordisk A/S Variantes du type protease et compositions
US6780629B2 (en) 1997-11-21 2004-08-24 Novozymes A/S Subtilase enzymes
US6773907B2 (en) 1997-11-21 2004-08-10 Peter Kamp Hansen Subtilase enzymes
US6376450B1 (en) 1998-10-23 2002-04-23 Chanchal Kumar Ghosh Cleaning compositions containing multiply-substituted protease variants
US6831053B1 (en) 1998-10-23 2004-12-14 The Procter & Gamble Company Bleaching compositions comprising multiply-substituted protease variants
CN1302106C (zh) * 1998-12-18 2007-02-28 诺沃奇梅兹有限公司 在活性位点环区中具有额外氨基酸残基的i－s1和i－s2亚组枯草杆菌酶
CA2355580C (fr) * 1998-12-18 2011-03-15 Novozymes A/S Enzymes subtilases des sous groupes i-s1 et i-s2 possedant un residu acide amine supplementaire dans un region en boucle de site actif
CN1342199B (zh) * 1998-12-18 2010-12-08 诺沃奇梅兹有限公司 在活性位点环区具有额外氨基酸残基的i-s1和i-s2亚族枯草杆菌酶
DE69937160T2 (de) * 1998-12-18 2008-06-19 Novozymes A/S Subtilase enzyme der i-s1 und i-s2 untergruppen, mit einem zusätzlichen aminosäurerest in einer aktiven schleifenregion
DE69936935T2 (de) * 1998-12-18 2008-05-15 Novozymes A/S Subtilase enzyme der i-s1 und i-s2 untergruppen mit einem zusätzlichen aminosäurerest in einer aktiven schleifenregion
ATE342966T1 (de) * 1998-12-18 2006-11-15 Novozymes As Subtilase enzyme der i-s1 und i-s2 untergruppen, mit einem zusätzlichen aminosäurerest in einer aktiven schleifenregion
CA2355574C (fr) * 1998-12-18 2011-06-07 Novozymes A/S Enzymes subtilases des sous-groupes i-s1 et i-s2 ayant un residu d'acide amine additionnel dans une region boucle de site actif
CA2355655C (fr) * 1998-12-18 2011-03-15 Novozymes A/S Enzymes subtilases des sous groupes i-s1 et i-s2 possedant un residu acide amine supplementaire dans un region en boucle de site actif
DE10153792A1 (de) 2001-10-31 2003-05-22 Henkel Kgaa Neue Alkalische Protease-Varianten und Wasch- und Reinigungsmittel enthaltend diese neuen Alkalischen Protease-Varianten
DE10162728A1 (de) 2001-12-20 2003-07-10 Henkel Kgaa Neue Alkalische Protease aus Bacillus gibsonii (DSM 14393) und Wasch-und Reinigungsmittel enthaltend diese neue Alkalische Protease
DE10162727A1 (de) 2001-12-20 2003-07-10 Henkel Kgaa Neue Alkalische Protease aus Bacillus gibsonii (DSM 14391) und Wasch-und Reinigungsmittel enthaltend diese neue Alkalische Protease
DE10163884A1 (de) 2001-12-22 2003-07-10 Henkel Kgaa Neue Alkalische Protease aus Bacillus sp. (DSM 14392) und Wasch- und Reinigungsmittel enthaltend diese neue Alkalische Protease
US7888093B2 (en) * 2002-11-06 2011-02-15 Novozymes A/S Subtilase variants
DE10260903A1 (de) * 2002-12-20 2004-07-08 Henkel Kgaa Neue Perhydrolasen
US7294499B2 (en) 2003-01-30 2007-11-13 Novozymes A/S Subtilases
DE102004029475A1 (de) * 2004-06-18 2006-01-26 Henkel Kgaa Neues enzymatisches Bleichsystem
DE102007044415A1 (de) 2007-09-17 2009-03-19 Henkel Ag & Co. Kgaa Leistungsverbesserte Proteasen und Wasch- und Reinigungsmittel enthaltend diese Proteasen
CA2743123A1 (fr) * 2008-11-11 2010-05-20 Danisco Us Inc. Compositions et procedes comprenant un variant de subtilisine
RU2733987C2 (ru) * 2015-05-13 2020-10-09 ДАНИСКО ЮЭс ИНК. Варианты протеазы клады aprl и их применения
DE102016204815A1 (de) * 2016-03-23 2017-09-28 Henkel Ag & Co. Kgaa Proteasen mit verbesserte Enzymstabilität in Waschmittel
DE102016204814A1 (de) * 2016-03-23 2017-09-28 Henkel Ag & Co. Kgaa Verbesserte Reinigungsleistung an Protein sensitiven Anschmutzungen
DE102017215629A1 (de) 2017-09-05 2019-03-07 Henkel Ag & Co. Kgaa Leistungsverbesserte Proteasevarianten III
WO2023225459A2 (fr) 2022-05-14 2023-11-23 Novozymes A/S Compositions et procédés de prévention, de traitement, de suppression et/ou d'élimination d'infestations et d'infections phytopathogènes

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5310675A (en) * 1983-06-24 1994-05-10 Genencor, Inc. Procaryotic carbonyl hydrolases
US4760025A (en) 1984-05-29 1988-07-26 Genencor, Inc. Modified enzymes and methods for making same
NZ208612A (en) * 1983-06-24 1991-09-25 Genentech Inc Method of producing "procaryotic carbonyl hydrolases" containing predetermined, site specific mutations
US5346823A (en) * 1984-05-29 1994-09-13 Genencor, Inc. Subtilisin modifications to enhance oxidative stability
US5763257A (en) * 1984-05-29 1998-06-09 Genencor International, Inc. Modified subtilisins having amino acid alterations
US5185258A (en) * 1984-05-29 1993-02-09 Genencor International, Inc. Subtilisin mutants
US5182204A (en) * 1984-05-29 1993-01-26 Genencor International, Inc. Non-human carbonyl hydrolase mutants, vectors encoding same and hosts transformed with said vectors
US5244791A (en) * 1984-05-29 1993-09-14 Genecor International, Inc. Methods of ester hydrolysis
US5972682A (en) * 1984-05-29 1999-10-26 Genencor International, Inc. Enzymatically active modified subtilisins
US5371008A (en) * 1984-05-29 1994-12-06 Genencor International, Inc. Substrate assisted catalysis
US5155033A (en) * 1989-01-06 1992-10-13 Genencor, Inc. Subtilisins modified at position 225 resulting in a shift in catalytic activity
US5371190A (en) * 1984-05-29 1994-12-06 Genencor International, Inc. Substrate assisted catalysis
WO1987004461A1 (fr) 1986-01-15 1987-07-30 Amgen ANALOGUES DE SUBTILISINE THERMIQUEMENT STABLE ET STABLE AU pH, ET LEUR PROCEDE DE PRODUCTION
JPS63502959A (ja) 1986-02-12 1988-11-02 ジェネックス、コ−ポレ−ション 突然変異誘発及びスクリ−ニング方法並びに生成物
US4908773A (en) 1987-04-06 1990-03-13 Genex Corporation Computer designed stabilized proteins and method for producing same
US4980288A (en) 1986-02-12 1990-12-25 Genex Corporation Subtilisin with increased thermal stability
US4990452A (en) * 1986-02-12 1991-02-05 Genex Corporation Combining mutations for stabilization of subtilisin
US5013657A (en) 1988-04-12 1991-05-07 Bryan Philip N Subtilisin mutations
US5240632A (en) * 1986-03-26 1993-08-31 Amway Corporation Machine dishwasher water spot control composition
SG30639G (en) * 1986-04-30 1995-09-01 Genencor Int Non-human carbonyl hydrolase mutants DNA sequences and vectors encoding same and hosts transformed with said vectors
NZ221627A (en) 1986-09-09 1993-04-28 Genencor Inc Preparation of enzymes, modifications, catalytic triads to alter ratios or transesterification/hydrolysis ratios
PT86864B (pt) * 1987-02-27 1992-05-29 Gist Brocades Nv Processo para clonagem molecular e expressao de genes que codificam para enzimas proteoliticas
US5260207A (en) * 1987-04-06 1993-11-09 Enzon Labs Inc. Engineering of electrostatic interactions at metal ion binding sites for the stabilization of proteins
EP0353250B1 (fr) * 1987-04-06 1999-09-08 Novo Nordisk A/S Stabilisation de proteines par mise au point des interactions electrostatiques aux sites de liaison d'ions metalliques
US4914031A (en) 1987-04-10 1990-04-03 Amgen, Inc. Subtilisin analogs
DK6488D0 (da) 1988-01-07 1988-01-07 Novo Industri As Enzymer
US5324653A (en) * 1988-02-11 1994-06-28 Gist-Brocades N.V. Recombinant genetic means for the production of serine protease muteins
PT89702B (pt) 1988-02-11 1994-04-29 Gist Brocades Nv Processo para a preparacao de novos enzimas proteoliticos e de detergentes que os contem
US6287841B1 (en) * 1988-02-11 2001-09-11 Genencor International, Inc. High alkaline serine protease
US5116741A (en) 1988-04-12 1992-05-26 Genex Corporation Biosynthetic uses of thermostable proteases
US5246849A (en) 1988-04-12 1993-09-21 Enzon, Inc. Thermally stable serine proteases
US5118623A (en) * 1988-05-27 1992-06-02 Solvay Enzymes, Inc. Bleach stable enzymes
WO1990014420A1 (fr) 1989-05-17 1990-11-29 Amgen Inc. Multiplication de subtilisines ayant subi une mutation
BR9006827A (pt) 1989-06-26 1991-08-06 Unilever Nv Composicoes detergentes enzimaticas
JPH04500384A (ja) 1989-06-26 1992-01-23 ユニリーバー・ナームローゼ・ベンノートシヤープ 酵素洗剤組成物
DK316989D0 (da) 1989-06-26 1989-06-26 Novo Nordisk As Enzymer
US5665587A (en) * 1989-06-26 1997-09-09 Novo Nordisk A/S Modified subtilisins and detergent compositions containing same
US5352603A (en) * 1989-08-31 1994-10-04 Kali-Chemie Ag Highly alkaline proteases
US6271012B1 (en) * 1989-10-11 2001-08-07 Genencor International, Inc. Protease muteins and their use in detergents
DE4009534A1 (de) * 1990-03-24 1991-09-26 Henkel Kgaa Fluessiges handreinigungsmittel
DK97190D0 (da) * 1990-04-19 1990-04-19 Novo Nordisk As Oxidationsstabile detergentenzymer
ATE187495T1 (de) * 1990-08-09 1999-12-15 Genentech Inc Serinproteasevarianten mit peptidligase aktivität
US5629173A (en) * 1990-08-09 1997-05-13 Genentech, Inc. Methods of use of serine protease variants having peptide ligase activity
DK271490D0 (da) * 1990-11-14 1990-11-14 Novo Nordisk As Detergentkomposition
FI932832A7 (fi) 1990-12-21 1993-08-13 Novozymes As Entsyymimutantteja, joilla on alhainen molekyylivarauksen vaihteluaste pH-alueella
US5482849A (en) * 1990-12-21 1996-01-09 Novo Nordisk A/S Subtilisin mutants
US5340735A (en) * 1991-05-29 1994-08-23 Cognis, Inc. Bacillus lentus alkaline protease variants with increased stability
EP0995801A1 (fr) * 1991-07-27 2000-04-26 Genencor International GmbH Procédé d'amélioration de la stabilité d'enzymes et enzymes stabilisées
US5275945A (en) * 1991-10-08 1994-01-04 Vista Chemical Company Alkaline proteases stable in heavy-duty detergent liquids
JP4028592B2 (ja) 1992-07-17 2007-12-26 ジェネンコー インターナショナル インコーポレイテッド 高アルカリ性セリンプロテアーゼ
US5567601A (en) * 1993-06-01 1996-10-22 University Of Maryland Subtilisin mutants lacking a primary calcium binding site
US5470733A (en) * 1993-06-01 1995-11-28 University Of Maryland Calcium free subtilisin mutants
US6436690B1 (en) * 1993-09-15 2002-08-20 The Procter & Gamble Company BPN′ variants having decreased adsorption and increased hydrolysis wherein one or more loop regions are substituted
CN1057123C (zh) 1993-09-15 2000-10-04 普罗格特-甘布尔公司 降低了吸附能力以及增加了水解能力的枯草杆菌蛋白酶bpn变体
AU1253695A (en) * 1993-10-14 1995-05-04 Procter & Gamble Company, The Bleaching compositions comprising protease enzymes
ES2287931T3 (es) * 1993-10-14 2007-12-16 THE PROCTER & GAMBLE COMPANY Composiciones limpiadoras que contienen proteasa.
ES2364776T3 (es) * 1994-02-24 2011-09-14 HENKEL AG & CO. KGAA Enzimas mejoradas y detergentes que las contienen.
US6599730B1 (en) * 1994-05-02 2003-07-29 Procter & Gamble Company Subtilisin 309 variants having decreased adsorption and increased hydrolysis
US5780285A (en) * 1995-03-03 1998-07-14 Genentech, Inc. Subtilisin variants capable of cleaving substrates containing dibasic residues

Also Published As

Publication number Publication date
IL117266A0 (en) 1996-06-18
CZ279397A3 (en) 1997-11-12
AU4868896A (en) 1996-10-02
HUP9800765A2 (hu) 1998-07-28
WO1996028566A2 (fr) 1996-09-19
WO1996028566A3 (fr) 1997-07-10
ZA961631B (en) 1996-09-06
CN1183119A (zh) 1998-05-27
HUP9800765A3 (en) 2001-01-29
BR9607356A (pt) 1999-06-15
MX9706851A (es) 1997-11-29
US6455295B1 (en) 2002-09-24
CA2214348A1 (fr) 1996-09-19
CA2214348C (fr) 2001-10-30
EP0813596A2 (fr) 1997-12-29
JPH11501812A (ja) 1999-02-16

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