MA23845A1 - Benzocyclopentane - oxazolidinones contenant de l'heteroatome - Google Patents
Benzocyclopentane - oxazolidinones contenant de l'heteroatomeInfo
- Publication number
- MA23845A1 MA23845A1 MA24205A MA24205A MA23845A1 MA 23845 A1 MA23845 A1 MA 23845A1 MA 24205 A MA24205 A MA 24205A MA 24205 A MA24205 A MA 24205A MA 23845 A1 MA23845 A1 MA 23845A1
- Authority
- MA
- Morocco
- Prior art keywords
- substd
- opt
- alkyl
- phenyl
- acyl
- Prior art date
Links
- PQNFLJBBNBOBRQ-UHFFFAOYSA-N indane Chemical compound C1=CC=C2CCCC2=C1 PQNFLJBBNBOBRQ-UHFFFAOYSA-N 0.000 title 2
- 125000000217 alkyl group Chemical group 0.000 abstract 9
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 6
- 125000002252 acyl group Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- -1 NHSO2R Chemical group 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- IZXIZTKNFFYFOF-UHFFFAOYSA-N 2-Oxazolidone Chemical compound O=C1NCCO1 IZXIZTKNFFYFOF-UHFFFAOYSA-N 0.000 abstract 1
- 125000004105 2-pyridyl group Chemical group N1=C([*])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000004575 3-pyrrolidinyl group Chemical group [H]N1C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 abstract 1
- 125000000339 4-pyridyl group Chemical group N1=C([H])C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
- 125000006163 5-membered heteroaryl group Chemical group 0.000 abstract 1
- 101100134925 Gallus gallus COR6 gene Proteins 0.000 abstract 1
- 101150020251 NR13 gene Proteins 0.000 abstract 1
- 229910006074 SO2NH2 Inorganic materials 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 abstract 1
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000004482 piperidin-4-yl group Chemical group N1CCC(CC1)* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000004001 thioalkyl group Chemical group 0.000 abstract 1
- 125000003944 tolyl group Chemical group 0.000 abstract 1
- ZBZJXHCVGLJWFG-UHFFFAOYSA-N trichloromethyl(.) Chemical compound Cl[C](Cl)Cl ZBZJXHCVGLJWFG-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D419/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
- C07D419/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D419/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
- C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
- C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19514769 | 1995-04-21 | ||
| DE19544106A DE19544106A1 (de) | 1995-04-21 | 1995-11-27 | Heteroatomhaltige Benzocyclopentanoxazolidinone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA23845A1 true MA23845A1 (fr) | 1996-12-31 |
Family
ID=26014539
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA24205A MA23845A1 (fr) | 1995-04-21 | 1996-04-19 | Benzocyclopentane - oxazolidinones contenant de l'heteroatome |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6069160A (fr) |
| EP (1) | EP0738726B1 (fr) |
| JP (1) | JP3967401B2 (fr) |
| CN (1) | CN1138582A (fr) |
| AT (1) | ATE206120T1 (fr) |
| AU (1) | AU705071B2 (fr) |
| BG (1) | BG100525A (fr) |
| CA (1) | CA2174473A1 (fr) |
| CZ (1) | CZ114296A3 (fr) |
| EE (1) | EE9600043A (fr) |
| ES (1) | ES2164182T3 (fr) |
| HR (1) | HRP960159A2 (fr) |
| HU (1) | HUP9601001A3 (fr) |
| IL (1) | IL117954A0 (fr) |
| MA (1) | MA23845A1 (fr) |
| MX (1) | MX9601399A (fr) |
| NO (1) | NO305909B1 (fr) |
| NZ (1) | NZ286400A (fr) |
| SG (1) | SG52774A1 (fr) |
| SK (1) | SK50096A3 (fr) |
| TR (1) | TR199600319A2 (fr) |
Families Citing this family (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9601666D0 (en) * | 1996-01-27 | 1996-03-27 | Zeneca Ltd | Chemical compounds |
| DE19604223A1 (de) | 1996-02-06 | 1997-08-07 | Bayer Ag | Neue substituierte Oxazolidinone |
| GB9702213D0 (en) * | 1996-02-24 | 1997-03-26 | Zeneca Ltd | Chemical compounds |
| GB9609919D0 (en) * | 1996-05-11 | 1996-07-17 | Zeneca Ltd | Chemical compounds |
| GB9717804D0 (en) | 1997-08-22 | 1997-10-29 | Zeneca Ltd | Chemical compounds |
| GB9717807D0 (en) | 1997-08-22 | 1997-10-29 | Zeneca Ltd | Chemical compounds |
| US6617453B1 (en) | 1997-10-24 | 2003-09-09 | Clariant Finance (Bvi) Limited | Triphendioxazine compounds |
| DE19747175A1 (de) | 1997-10-24 | 1999-04-29 | Clariant Int Ltd | Chlorhaltige Triphendioxazin-Verbindungen |
| ATE315394T1 (de) | 1997-11-10 | 2006-02-15 | Bristol Myers Squibb Co | Benzothiazole als protein tyrosin-kinase inhibitoren |
| GB9725244D0 (en) | 1997-11-29 | 1998-01-28 | Zeneca Ltd | Chemical compounds |
| US6562844B2 (en) | 1998-01-23 | 2003-05-13 | Pharmacia & Upjohn Company | Oxazolidinone combinatorial libraries, compositions and methods of preparation |
| US7002020B1 (en) | 1998-01-23 | 2006-02-21 | Pharmacia & Upjohn Company | Oxazolidinone combinatorial libraries, compositions and methods of preparation |
| BR9907183A (pt) | 1998-01-23 | 2003-06-10 | Versicor Inc | Colet neas combinatórias de oxazolidinona, composições e processos de preparação |
| WO2000029409A1 (fr) * | 1998-11-17 | 2000-05-25 | Bayer Aktiengesellschaft | Nouveaux derives d'oxazolidone substitues par un heterocyclyle |
| DE19905278A1 (de) * | 1999-02-09 | 2000-08-10 | Bayer Ag | Oxazolidinone und ihre Verwendung als antibakterielle Mittel |
| DE19913401A1 (de) | 1999-03-25 | 2000-09-28 | Clariant Gmbh | Verfahren zur Herstellung von Dioxazin-Verbindungen |
| WO2001009107A1 (fr) | 1999-07-28 | 2001-02-08 | Pharmacia & Upjohn Company | Oxazolidinones et leur utilisation comme anti-infectieux |
| GB9928568D0 (en) * | 1999-12-03 | 2000-02-02 | Zeneca Ltd | Chemical compounds |
| US6518285B2 (en) * | 1999-12-21 | 2003-02-11 | Ortho Mcneil Pharmaceutical, Inc. | Piperidinyloxy and pyrrolidinyloxy oxazolidinone antibacterials |
| DE19962924A1 (de) | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
| PE20011124A1 (es) | 2000-03-31 | 2001-10-28 | Upjohn Co | Nuevos agentes antibacterianos de benzosultam oxazolidinona |
| GB0009803D0 (en) * | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
| ES2256318T3 (es) * | 2000-10-17 | 2006-07-16 | PHARMACIA & UPJOHN COMPANY LLC | Metodos de produccion de compuestos de oxazolidinona. |
| DE60131015T2 (de) * | 2000-12-15 | 2008-07-10 | Vertex Pharmaceuticals Inc., Cambridge | Bakterielle gyrase-hemmer und deren verwendung |
| ATE304536T1 (de) * | 2001-04-17 | 2005-09-15 | Merck & Co Inc | Bicyclo(3,1,0)hexan als strukturelement enthaltende oxazolidinon-antibiotika und deren derivate |
| IL158484A0 (en) | 2001-04-18 | 2004-05-12 | Euro Celtique Sa | Nociceptin analogs |
| DE10129725A1 (de) | 2001-06-20 | 2003-01-02 | Bayer Ag | Kombinationstherapie substituierter Oxazolidinone |
| WO2003048136A1 (fr) * | 2001-11-29 | 2003-06-12 | Merck & Co., Inc. | Antibiotiques de type oxazolidinone contenant de l'hexane cyclopropyle et derives de ceux-ci |
| US7141588B2 (en) * | 2002-02-25 | 2006-11-28 | Pfizer, Inc. | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives |
| AR038536A1 (es) * | 2002-02-25 | 2005-01-19 | Upjohn Co | N-aril-2-oxazolidinona-5- carboxamidas y sus derivados |
| EP1490059A1 (fr) * | 2002-03-29 | 2004-12-29 | Pharmacia & Upjohn Company LLC | Administration orale, parenterale ou intraveineuse d'oxazolidinones utilisees dans le traitement des infections du pied causees par le diabete |
| DE60304360T2 (de) * | 2002-08-12 | 2006-11-16 | Pharmacia & Upjohn Co. Llc, Kalamazoo | N-aryl-2-oxazolidinone und deren derivate |
| WO2004026848A1 (fr) * | 2002-09-20 | 2004-04-01 | Lupin Limited | Derives d'oxazolidinone, leur procede de preparation et leur utilisation comme agents antimycobacterients |
| ATE344036T1 (de) * | 2002-11-21 | 2006-11-15 | Pharmacia & Upjohn Co Llc | N-(4-(piperazin-1-yl)-phenyl-2-oxazolidinon-5- carbonsäureamid-derivate und verwandte verbindungen als antibakterielle mittel |
| DE10300111A1 (de) * | 2003-01-07 | 2004-07-15 | Bayer Healthcare Ag | Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid |
| US8193352B2 (en) | 2003-01-31 | 2012-06-05 | Vertex Pharmaceuticals Incorporated | Gyrase inhibitors and uses thereof |
| US8404852B2 (en) | 2003-01-31 | 2013-03-26 | Vertex Pharmaceuticals Incorporated | Gyrase inhibitors and uses thereof |
| US7582641B2 (en) | 2003-01-31 | 2009-09-01 | Vertex Pharmaceuticals Incorporated | Gyrase inhibitors and uses thereof |
| US7618974B2 (en) | 2003-01-31 | 2009-11-17 | Vertex Pharmaceuticals Incorporated | Gyrase inhibitors and uses thereof |
| US7569591B2 (en) | 2003-01-31 | 2009-08-04 | Vertex Pharmaceuticals Incorporated | Gyrase inhibitors and uses thereof |
| AR042956A1 (es) | 2003-01-31 | 2005-07-13 | Vertex Pharma | Inhibidores de girasa y usos de los mismos |
| CA2515269A1 (fr) * | 2003-02-07 | 2004-08-19 | Warner-Lambert Company Llc | Derives d'oxazolidinone n-substitues par un noyau bicyclique, utilises comme agents antibacteriens |
| BRPI0407252A (pt) * | 2003-02-07 | 2006-01-31 | Warner Lambert Co | Agentes antibacterianos. |
| US7012088B2 (en) * | 2003-02-24 | 2006-03-14 | Pharmacia & Upjohn Company | Indolone oxazolidinones and derivatives thereof |
| US20040204463A1 (en) * | 2003-04-01 | 2004-10-14 | Harris Christina Renee | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives |
| ATE471937T1 (de) * | 2003-07-02 | 2010-07-15 | Merck Sharp & Dohme | Cyclopropylgruppensubstituierte oxazolidinonantibiotika und derivate davon |
| US20070185132A1 (en) * | 2003-07-02 | 2007-08-09 | Yasumichi Fukuda | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereo |
| CA2529292A1 (fr) * | 2003-07-02 | 2005-01-20 | Merck & Co., Inc. | Antibiotiques a base d'oxazolidinone et derives |
| AU2004256086B2 (en) * | 2003-07-02 | 2007-12-06 | Kyorin Pharmaceutical Co., Ltd. | Oxazolidinone antibiotics and derivatives thereof |
| US7304050B2 (en) * | 2003-09-16 | 2007-12-04 | Pfizer Inc. | Antibacterial agents |
| DE10355461A1 (de) | 2003-11-27 | 2005-06-23 | Bayer Healthcare Ag | Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung |
| WO2005082897A1 (fr) * | 2004-01-28 | 2005-09-09 | Pharmacia & Upjohn Company Llc | Agents antibacteriens oxazolidinone |
| WO2005082900A2 (fr) * | 2004-01-28 | 2005-09-09 | Pharmacia & Upjohn Company Llc | Amidoxines d'oxazolidinone utilisees en tant qu'agents antibacteriens |
| EP1781642A1 (fr) * | 2004-08-06 | 2007-05-09 | Pharmacia & Upjohn Company LLC | Oxazolidinones contenant des oxindoles en tant qu'agents antibacteriens |
| DE102004062475A1 (de) * | 2004-12-24 | 2006-07-06 | Bayer Healthcare Ag | Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung |
| EP1685841A1 (fr) | 2005-01-31 | 2006-08-02 | Bayer Health Care Aktiengesellschaft | Prevention et traitement de troubles thromboemboliques |
| EP1869029A1 (fr) * | 2005-04-06 | 2007-12-26 | Pharmacia & Upjohn Company LLC | Oxindole oxazolidinone utilise en tant qu'agent antibacterien |
| DE102005045518A1 (de) | 2005-09-23 | 2007-03-29 | Bayer Healthcare Ag | 2-Aminoethoxyessigsäure-Derivate und ihre Verwendung |
| CA2624310C (fr) | 2005-10-04 | 2014-01-07 | Bayer Healthcare Ag | Forme polymorphique de 5 chloro n ({5s) 2 oxo 3 [4 (3 oxo 4 morpholinyl)phenyl] 1,3 oxazolidin 5 yl} methyl) 2 thiophenecarboxamidel)-2-thiophenecarboxamide |
| DE102005047561A1 (de) | 2005-10-04 | 2007-04-05 | Bayer Healthcare Ag | Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung |
| DE102005048824A1 (de) * | 2005-10-10 | 2007-04-12 | Bayer Healthcare Ag | Behandlung und Prophylaxe von Mikroangiopathien |
| DE102006051625A1 (de) * | 2006-11-02 | 2008-05-08 | Bayer Materialscience Ag | Kombinationstherapie substituierter Oxazolidinone |
| KR101882172B1 (ko) | 2011-01-14 | 2018-07-26 | 스페로 트리넴, 인코포레이티드 | 자이라제 및 토포이소머라제 ⅳ 억제제의 제조방법 |
| RU2609259C2 (ru) | 2011-01-14 | 2017-01-31 | Сперо Тринем, Инк. | Пиримидиновые ингибиторы гиразы и топоизомеразы iv |
| US8476281B2 (en) | 2011-01-14 | 2013-07-02 | Vertex Pharmaceuticals Incorporated | Solid forms of gyrase inhibitor (R)-1-ethyl-3-[6-fluoro-5-[2-(1-hydroxy-1-methyl-ethyl)pyrimidin-5-yl]-7-(tetrahydrofuran-2-yl)-1H-benzimidazol-2-yl]urea |
| BR112013017977A2 (pt) | 2011-01-14 | 2019-09-24 | Vertex Pharma | formas sólidas de inibidor de girase (r) 1-etil-3-[5-[2-{1-hidroxi-1-metil-etil}pirimidin-5-il]-7-(tetrai-drofuran-2-il)-1h-benzimidazol-2-il]ureia |
| CN103702994B (zh) | 2011-06-20 | 2016-03-23 | 沃泰克斯药物股份有限公司 | 旋转酶和拓扑异构酶抑制剂的磷酸酯 |
| WO2014014845A1 (fr) | 2012-07-18 | 2014-01-23 | Vertex Pharmaceuticals Incorporated | Thérapie combinée comprenant de la 1-éthyl-3[5-[-2-{1-hydroxy-1-méthyl-éthyl}pyrimidin-5-yl]-7-(tétrahydrofuran-2-yl}-1h-benzimidazol-2-yl]urée et ses dérivés pour traiter des maladies mycobactériennes |
| US9018216B2 (en) | 2012-07-18 | 2015-04-28 | Vertex Pharmaceuticals Incorporated | Solid forms of (R)-2-(5-(2-(3-ethylureido)-6-fluoro-7-(tetrahydrofuran-2-yl)-1H-benzo[d]imidazol-5-yl)pyrimidin-2-yl)propan-2-yl dihydrogen phosphate and salts thereof |
| ES2670517T3 (es) * | 2013-01-30 | 2018-05-30 | Sumitomo Chemical Company, Limited | Compuesto de amida, un agente de control de plagas de artrópodos y un método para controlar las plagas de artrópodos |
| CN114075439B (zh) * | 2021-12-07 | 2023-07-28 | 西安瑞联新材料股份有限公司 | 一种苯并戊烷类液晶化合物及其组合物 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4705799A (en) * | 1983-06-07 | 1987-11-10 | E. I. Du Pont De Nemours And Company | Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents |
| DE3723797A1 (de) * | 1987-07-18 | 1989-01-26 | Merck Patent Gmbh | Oxazolidinone |
| US4801600A (en) * | 1987-10-09 | 1989-01-31 | E. I. Du Pont De Nemours And Company | Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents |
| US4965268A (en) * | 1987-10-09 | 1990-10-23 | E. I. Du Pont De Nemours And Company | Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents |
| US4921869A (en) * | 1987-10-09 | 1990-05-01 | E. I. Du Pont De Nemours And Company | Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents |
| CA1320730C (fr) * | 1987-10-16 | 1993-07-27 | The Du Pont Merck Pharmaceutical Company | Derives d'aminomethyloxooxazolidinylaroylbenzene, agents antibacteriens |
| US5254577A (en) * | 1988-07-29 | 1993-10-19 | The Du Pont Merck Pharmaceutical Company | Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents |
| JP2865211B2 (ja) * | 1988-09-15 | 1999-03-08 | ファルマシア・アンド・アップジョン・カンパニー | ５’―インドリニル―５β―アミドメチルオキサゾリジン―２―オン類、３―（縮合環置換）フェニル―５β―アミドメチルオキサゾリジン―２―オン類および３―（窒素原子置換）フェニル―５β―アミドメチルオキサゾリジン―２―オン類 |
| JP2669579B2 (ja) * | 1991-10-23 | 1997-10-29 | エーザイ株式会社 | オキサゾリドン誘導体 |
| DE19514313A1 (de) * | 1994-08-03 | 1996-02-08 | Bayer Ag | Benzoxazolyl- und Benzothiazolyloxazolidinone |
-
1996
- 1996-04-04 HR HR19544106.0A patent/HRP960159A2/hr not_active Application Discontinuation
- 1996-04-09 ES ES96105539T patent/ES2164182T3/es not_active Expired - Lifetime
- 1996-04-09 AT AT96105539T patent/ATE206120T1/de not_active IP Right Cessation
- 1996-04-09 EP EP96105539A patent/EP0738726B1/fr not_active Expired - Lifetime
- 1996-04-12 US US08/631,516 patent/US6069160A/en not_active Expired - Fee Related
- 1996-04-15 MX MX9601399A patent/MX9601399A/es unknown
- 1996-04-16 JP JP11711796A patent/JP3967401B2/ja not_active Expired - Fee Related
- 1996-04-17 HU HU9601001A patent/HUP9601001A3/hu unknown
- 1996-04-17 TR TR96/00319A patent/TR199600319A2/xx unknown
- 1996-04-17 AU AU50735/96A patent/AU705071B2/en not_active Ceased
- 1996-04-18 IL IL11795496A patent/IL117954A0/xx unknown
- 1996-04-18 CA CA002174473A patent/CA2174473A1/fr not_active Abandoned
- 1996-04-18 NZ NZ286400A patent/NZ286400A/en unknown
- 1996-04-19 CZ CZ961142A patent/CZ114296A3/cs unknown
- 1996-04-19 SG SG1996009312A patent/SG52774A1/en unknown
- 1996-04-19 MA MA24205A patent/MA23845A1/fr unknown
- 1996-04-19 NO NO961559A patent/NO305909B1/no unknown
- 1996-04-19 BG BG100525A patent/BG100525A/xx unknown
- 1996-04-19 CN CN96106152A patent/CN1138582A/zh active Pending
- 1996-04-19 EE EE9600043A patent/EE9600043A/xx unknown
- 1996-04-19 SK SK500-96A patent/SK50096A3/sk unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HU9601001D0 (en) | 1996-06-28 |
| EP0738726B1 (fr) | 2001-09-26 |
| SG52774A1 (en) | 1998-09-28 |
| IL117954A0 (en) | 1996-08-04 |
| TR199600319A2 (tr) | 1996-11-21 |
| HUP9601001A2 (hu) | 1998-04-28 |
| AU705071B2 (en) | 1999-05-13 |
| JP3967401B2 (ja) | 2007-08-29 |
| ATE206120T1 (de) | 2001-10-15 |
| HUP9601001A3 (en) | 1999-03-01 |
| HRP960159A2 (en) | 1997-08-31 |
| JPH08301869A (ja) | 1996-11-19 |
| CZ114296A3 (en) | 1997-07-16 |
| NO961559L (no) | 1996-10-22 |
| CA2174473A1 (fr) | 1996-10-22 |
| BG100525A (en) | 1997-03-31 |
| CN1138582A (zh) | 1996-12-25 |
| US6069160A (en) | 2000-05-30 |
| MX9601399A (es) | 1997-04-30 |
| SK50096A3 (en) | 1997-05-07 |
| EE9600043A (et) | 1996-12-16 |
| NZ286400A (en) | 1998-04-27 |
| ES2164182T3 (es) | 2002-02-16 |
| NO305909B1 (no) | 1999-08-16 |
| NO961559D0 (no) | 1996-04-19 |
| AU5073596A (en) | 1996-10-31 |
| EP0738726A1 (fr) | 1996-10-23 |
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