MA24427A1 - Procede pour la preparation de nouveaux composes - Google Patents

Procede pour la preparation de nouveaux composes

Info

Publication number
MA24427A1
MA24427A1 MA24903A MA24903A MA24427A1 MA 24427 A1 MA24427 A1 MA 24427A1 MA 24903 A MA24903 A MA 24903A MA 24903 A MA24903 A MA 24903A MA 24427 A1 MA24427 A1 MA 24427A1
Authority
MA
Morocco
Prior art keywords
preparation
new compounds
compounds
new
Prior art date
Application number
MA24903A
Other languages
English (en)
Original Assignee
Smithkline Beecham Plc
Symphar Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc, Symphar Sa filed Critical Smithkline Beecham Plc
Publication of MA24427A1 publication Critical patent/MA24427A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/58—Pyridine rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MA24903A 1996-12-20 1997-12-18 Procede pour la preparation de nouveaux composes MA24427A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9626615.0A GB9626615D0 (en) 1996-12-20 1996-12-20 Novel compounds

Publications (1)

Publication Number Publication Date
MA24427A1 true MA24427A1 (fr) 1998-07-01

Family

ID=10804837

Family Applications (1)

Application Number Title Priority Date Filing Date
MA24903A MA24427A1 (fr) 1996-12-20 1997-12-18 Procede pour la preparation de nouveaux composes

Country Status (31)

Country Link
US (2) US6303784B1 (fr)
EP (1) EP0946572B1 (fr)
JP (1) JP2001506667A (fr)
KR (1) KR20000069609A (fr)
CN (1) CN1105117C (fr)
AP (1) AP9901546A0 (fr)
AR (1) AR008541A1 (fr)
AT (1) ATE255117T1 (fr)
AU (1) AU5858898A (fr)
BG (1) BG103574A (fr)
BR (1) BR9714650A (fr)
CA (1) CA2275696A1 (fr)
CO (1) CO4930276A1 (fr)
DE (1) DE69726449T2 (fr)
DZ (1) DZ2377A1 (fr)
EA (1) EA199900580A1 (fr)
GB (1) GB9626615D0 (fr)
HU (1) HUP0002171A3 (fr)
ID (1) ID22053A (fr)
IL (1) IL130334A0 (fr)
MA (1) MA24427A1 (fr)
NO (1) NO993001D0 (fr)
NZ (1) NZ335884A (fr)
OA (1) OA11068A (fr)
PE (1) PE46799A1 (fr)
PL (1) PL334189A1 (fr)
SK (1) SK81099A3 (fr)
TR (1) TR199901423T2 (fr)
TW (1) TW434221B (fr)
WO (1) WO1998028310A1 (fr)
ZA (1) ZA9711431B (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1686119B1 (fr) 2000-02-16 2009-07-29 Smithkline Beecham Plc Dérivés de Pyrimidine-5-one comme inhibiteurs LDL-PLA2
US7442689B2 (en) 2000-02-29 2008-10-28 Medicure International Inc. Cardioprotective phosphonates and malonates
EP1531157B1 (fr) * 2000-02-29 2008-03-19 Medicure International Inc. Phosphonates cardioprotecteurs
AU3718501A (en) * 2000-02-29 2001-09-12 Medicure Int Inc Cardioprotective phosphonates and malonates
US6897228B2 (en) 2000-07-07 2005-05-24 Medicure International Inc. Pyridoxine and pyridoxal analogues: new uses
AU9479201A (en) 2000-09-27 2002-04-08 Ilex Oncology Res S A Alpha-substituted beta-aminoethyl phosphonates
US20030114421A1 (en) * 2000-09-27 2003-06-19 Phan Hieu Trung Alpha-substituted beta-aminoethyl phosphonate derivatives
GB0024808D0 (en) 2000-10-10 2000-11-22 Smithkline Beecham Plc Novel compounds
GB0025849D0 (en) * 2000-10-23 2000-12-06 Smithkline Beecham Plc Novel compounds
EP1482953A4 (fr) * 2002-02-11 2006-12-13 Ilex Products Inc Derives alpha-substitues d'heteroarylalkyl phosphonate
US7208481B2 (en) * 2002-02-19 2007-04-24 Ilex Products, Inc. Aminodiphosphonate apolipoprotein E modulators
US7459468B2 (en) 2004-10-28 2008-12-02 Medicure International, Inc. Aryl sulfonic pyridoxines as antiplatelet agents
JP4824968B2 (ja) * 2005-08-18 2011-11-30 株式会社クレハ ホスホン酸誘導体及びその酸付加塩、並びにそれを用いた農園芸用病害防除剤
PE20140421A1 (es) 2010-12-06 2014-04-26 Glaxo Group Ltd COMPUESTOS DERIVADOS DE PIRIMIDINONA COMO INHIBIDORES DE Lp-PLA2
EP2739627A4 (fr) 2011-07-27 2015-01-21 Glaxo Group Ltd Composés 2,3-dihydroimidazo[1,2-c]pyrimidin-5(1h)-one et utilisation en tant qu'inhibiteurs de lp-pla2
AR087309A1 (es) 2011-07-27 2014-03-12 Glaxo Group Ltd Compuesto heterociclico de anillos condensados sustituido, composicion farmaceutica que lo comprende y su uso para la fabricacion de un medicamento para el tratamiento de enfermedades neurogenerativas y aterosclerosis
CN103906744A (zh) 2011-09-01 2014-07-02 葛兰素集团有限公司 新晶型
BR112015017768A2 (pt) 2013-01-25 2017-07-11 Glaxosmithkline Ip Dev Ltd compostos
AU2014210260B2 (en) 2013-01-25 2016-08-04 Glaxosmithkline Intellectual Property Development Limited Bicyclic pyrimidone compounds as inhibitors of Lp-PLA2
EP2948452B1 (fr) 2013-01-25 2017-08-09 GlaxoSmithKline Intellectual Property Development Limited Inhibiteurs de la phospholipase associée aux lipoprotéines a2 (lp-pla2) à base de 2,3-dihydro-imidazol[1,2-c]pyrimidin-5(1 h)-one
WO2016012917A1 (fr) 2014-07-22 2016-01-28 Glaxosmithkline Intellectual Property Development Limited Dérivés 1,2,3,5-tétrahydro-imidazo [1,2-c]pyrimidine utiles pour le traitement de maladies et de troubles médiés par la lp-pla2
WO2016012916A1 (fr) 2014-07-22 2016-01-28 Glaxosmithkline Intellectual Property Development Limited Dérivés 1,2,3,5-tétrahydro-imidazo [1,2-c]pyrimidine utiles pour le traitement de maladies et de troubles médiés par la lp-pla2
CN112778331B (zh) 2019-11-09 2022-07-05 上海赛默罗生物科技有限公司 三环二氢咪唑并嘧啶酮衍生物、其制备方法、药物组合物和用途
CN115304620A (zh) 2021-05-07 2022-11-08 上海赛默罗生物科技有限公司 嘧啶酮衍生物、其制备方法、药物组合物和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH683996A5 (fr) * 1992-03-05 1994-06-30 Symphar Sa Dérivés aminophosphonates substitués, leur procédé de préparation et compositions pharmaceutiques les contenant.
DE4433244A1 (de) * 1994-09-19 1996-03-28 Hoechst Ag Aminomethylphosphon- und Aminomethylphosphinsäure-Derivate und deren Verwendung zur Behandlung von degenerativen Gelenkserkrankungen
CH690264A5 (fr) 1995-06-30 2000-06-30 Symphar Sa Dérivés aminophosphonates substitués, leur procédé de préparation et leur utilisation pour la préparation de compositions pharmaceutiques.
GB9626536D0 (en) 1996-12-20 1997-02-05 Symphar Sa Novel compounds

Also Published As

Publication number Publication date
EP0946572A1 (fr) 1999-10-06
EA199900580A1 (ru) 1999-12-29
BG103574A (bg) 2000-11-30
ATE255117T1 (de) 2003-12-15
NO993001L (no) 1999-06-18
HUP0002171A3 (en) 2002-12-28
US20020082423A1 (en) 2002-06-27
PE46799A1 (es) 1999-06-24
NO993001D0 (no) 1999-06-18
AR008541A1 (es) 2000-01-19
CN1240451A (zh) 2000-01-05
IL130334A0 (en) 2000-06-01
ID22053A (id) 1999-08-26
CA2275696A1 (fr) 1998-07-02
US6303784B1 (en) 2001-10-16
KR20000069609A (ko) 2000-11-25
CO4930276A1 (es) 2000-06-27
AP9901546A0 (en) 1999-06-30
CN1105117C (zh) 2003-04-09
DE69726449D1 (en) 2004-01-08
DZ2377A1 (fr) 2002-12-28
PL334189A1 (en) 2000-02-14
TW434221B (en) 2001-05-16
HUP0002171A2 (hu) 2001-05-28
WO1998028310A1 (fr) 1998-07-02
TR199901423T2 (xx) 1999-10-21
BR9714650A (pt) 2000-10-03
GB9626615D0 (en) 1997-02-05
NZ335884A (en) 2000-11-24
AU5858898A (en) 1998-07-17
JP2001506667A (ja) 2001-05-22
SK81099A3 (en) 1999-11-08
EP0946572B1 (fr) 2003-11-26
OA11068A (en) 2003-03-10
ZA9711431B (en) 1999-06-21
DE69726449T2 (de) 2004-08-26

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