MA24427A1 - Procede pour la preparation de nouveaux composes - Google Patents

Procede pour la preparation de nouveaux composes

Info

Publication number
MA24427A1
MA24427A1 MA24903A MA24903A MA24427A1 MA 24427 A1 MA24427 A1 MA 24427A1 MA 24903 A MA24903 A MA 24903A MA 24903 A MA24903 A MA 24903A MA 24427 A1 MA24427 A1 MA 24427A1
Authority
MA
Morocco
Prior art keywords
preparation
new compounds
compounds
new
Prior art date
Application number
MA24903A
Other languages
English (en)
Original Assignee
Smithkline Beecham Plc
Symphar Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc, Symphar Sa filed Critical Smithkline Beecham Plc
Publication of MA24427A1 publication Critical patent/MA24427A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/58—Pyridine rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MA24903A 1996-12-20 1997-12-18 Procede pour la preparation de nouveaux composes MA24427A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9626615.0A GB9626615D0 (en) 1996-12-20 1996-12-20 Novel compounds

Publications (1)

Publication Number Publication Date
MA24427A1 true MA24427A1 (fr) 1998-07-01

Family

ID=10804837

Family Applications (1)

Application Number Title Priority Date Filing Date
MA24903A MA24427A1 (fr) 1996-12-20 1997-12-18 Procede pour la preparation de nouveaux composes

Country Status (31)

Country Link
US (2) US6303784B1 (fr)
EP (1) EP0946572B1 (fr)
JP (1) JP2001506667A (fr)
KR (1) KR20000069609A (fr)
CN (1) CN1105117C (fr)
AP (1) AP9901546A0 (fr)
AR (1) AR008541A1 (fr)
AT (1) ATE255117T1 (fr)
AU (1) AU5858898A (fr)
BG (1) BG103574A (fr)
BR (1) BR9714650A (fr)
CA (1) CA2275696A1 (fr)
CO (1) CO4930276A1 (fr)
DE (1) DE69726449T2 (fr)
DZ (1) DZ2377A1 (fr)
EA (1) EA199900580A1 (fr)
GB (1) GB9626615D0 (fr)
HU (1) HUP0002171A3 (fr)
ID (1) ID22053A (fr)
IL (1) IL130334A0 (fr)
MA (1) MA24427A1 (fr)
NO (1) NO993001D0 (fr)
NZ (1) NZ335884A (fr)
OA (1) OA11068A (fr)
PE (1) PE46799A1 (fr)
PL (1) PL334189A1 (fr)
SK (1) SK81099A3 (fr)
TR (1) TR199901423T2 (fr)
TW (1) TW434221B (fr)
WO (1) WO1998028310A1 (fr)
ZA (1) ZA9711431B (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60139429D1 (de) 2000-02-16 2009-09-10 Smithkline Beecham Plc Pyrimidin-5-Onderivate als LDL-PLA2 Inhibitoren
EP1531157B1 (fr) * 2000-02-29 2008-03-19 Medicure International Inc. Phosphonates cardioprotecteurs
WO2001064692A1 (fr) 2000-02-29 2001-09-07 Medicure International Inc. Phosphonates et malonates cardioprotecteurs
US7442689B2 (en) 2000-02-29 2008-10-28 Medicure International Inc. Cardioprotective phosphonates and malonates
US6897228B2 (en) 2000-07-07 2005-05-24 Medicure International Inc. Pyridoxine and pyridoxal analogues: new uses
US20030114421A1 (en) * 2000-09-27 2003-06-19 Phan Hieu Trung Alpha-substituted beta-aminoethyl phosphonate derivatives
CN1489596A (zh) * 2000-09-27 2004-04-14 �Ʒ� α-取代的β-氨基乙基膦酸酯类化合物
GB0024808D0 (en) 2000-10-10 2000-11-22 Smithkline Beecham Plc Novel compounds
GB0025849D0 (en) * 2000-10-23 2000-12-06 Smithkline Beecham Plc Novel compounds
CA2475882A1 (fr) * 2002-02-11 2003-08-21 Ilex Products, Inc. Derives alpha-substitues d'heteroarylalkyl phosphonate
US7208481B2 (en) * 2002-02-19 2007-04-24 Ilex Products, Inc. Aminodiphosphonate apolipoprotein E modulators
US7459468B2 (en) 2004-10-28 2008-12-02 Medicure International, Inc. Aryl sulfonic pyridoxines as antiplatelet agents
JP4824968B2 (ja) * 2005-08-18 2011-11-30 株式会社クレハ ホスホン酸誘導体及びその酸付加塩、並びにそれを用いた農園芸用病害防除剤
US8637536B2 (en) 2010-12-06 2014-01-28 Glaxo Group Limited Pyrimidinone compounds for use in the treatment of diseases or conditions mediated by Lp-PLA2
EP2739627A4 (fr) 2011-07-27 2015-01-21 Glaxo Group Ltd Composés 2,3-dihydroimidazo[1,2-c]pyrimidin-5(1h)-one et utilisation en tant qu'inhibiteurs de lp-pla2
US9273054B2 (en) 2011-07-27 2016-03-01 Glaxo Group Limited Substituted pyrimido[1,6-a]pyrimidines as Lp-PLA2 inhibitors
US9227953B2 (en) 2011-09-01 2016-01-05 Glaxo Group Limited Crystal form
CA2899124A1 (fr) 2013-01-25 2014-07-31 Glaxosmithkline Intellectual Property Development Limited Composes
JP2016505053A (ja) 2013-01-25 2016-02-18 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ Ｌｐ‐ＰＬＡ２の阻害剤としての二環式ピリミドン化合物
WO2014114694A1 (fr) 2013-01-25 2014-07-31 Glaxosmithkline Intellectual Property Development Limited Inhibiteurs de la phospholipase associée aux lipoprotéines a2 (lp-pla2) à base de 2,3-dihydro-imidazol[1,2-c]pyrimidin-5(1 h)-one
WO2016012917A1 (fr) 2014-07-22 2016-01-28 Glaxosmithkline Intellectual Property Development Limited Dérivés 1,2,3,5-tétrahydro-imidazo [1,2-c]pyrimidine utiles pour le traitement de maladies et de troubles médiés par la lp-pla2
WO2016012916A1 (fr) 2014-07-22 2016-01-28 Glaxosmithkline Intellectual Property Development Limited Dérivés 1,2,3,5-tétrahydro-imidazo [1,2-c]pyrimidine utiles pour le traitement de maladies et de troubles médiés par la lp-pla2
CN114805389B (zh) 2019-11-09 2023-08-29 上海赛默罗生物科技有限公司 三环二氢咪唑并嘧啶酮衍生物、其制备方法、药物组合物和用途
CN115304620A (zh) 2021-05-07 2022-11-08 上海赛默罗生物科技有限公司 嘧啶酮衍生物、其制备方法、药物组合物和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH683996A5 (fr) * 1992-03-05 1994-06-30 Symphar Sa Dérivés aminophosphonates substitués, leur procédé de préparation et compositions pharmaceutiques les contenant.
DE4433244A1 (de) 1994-09-19 1996-03-28 Hoechst Ag Aminomethylphosphon- und Aminomethylphosphinsäure-Derivate und deren Verwendung zur Behandlung von degenerativen Gelenkserkrankungen
CH690264A5 (fr) 1995-06-30 2000-06-30 Symphar Sa Dérivés aminophosphonates substitués, leur procédé de préparation et leur utilisation pour la préparation de compositions pharmaceutiques.
GB9626536D0 (en) 1996-12-20 1997-02-05 Symphar Sa Novel compounds

Also Published As

Publication number Publication date
GB9626615D0 (en) 1997-02-05
CN1240451A (zh) 2000-01-05
NZ335884A (en) 2000-11-24
ATE255117T1 (de) 2003-12-15
WO1998028310A1 (fr) 1998-07-02
US20020082423A1 (en) 2002-06-27
NO993001L (no) 1999-06-18
ZA9711431B (en) 1999-06-21
OA11068A (en) 2003-03-10
BR9714650A (pt) 2000-10-03
TW434221B (en) 2001-05-16
AR008541A1 (es) 2000-01-19
DZ2377A1 (fr) 2002-12-28
EA199900580A1 (ru) 1999-12-29
DE69726449T2 (de) 2004-08-26
US6303784B1 (en) 2001-10-16
PE46799A1 (es) 1999-06-24
EP0946572B1 (fr) 2003-11-26
AU5858898A (en) 1998-07-17
NO993001D0 (no) 1999-06-18
TR199901423T2 (xx) 1999-10-21
ID22053A (id) 1999-08-26
EP0946572A1 (fr) 1999-10-06
PL334189A1 (en) 2000-02-14
CO4930276A1 (es) 2000-06-27
KR20000069609A (ko) 2000-11-25
HUP0002171A3 (en) 2002-12-28
IL130334A0 (en) 2000-06-01
JP2001506667A (ja) 2001-05-22
CN1105117C (zh) 2003-04-09
HUP0002171A2 (hu) 2001-05-28
DE69726449D1 (en) 2004-01-08
CA2275696A1 (fr) 1998-07-02
AP9901546A0 (en) 1999-06-30
SK81099A3 (en) 1999-11-08
BG103574A (bg) 2000-11-30

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