|
CN1154505C
(zh)
*
|
1997-02-05 |
2004-06-23 |
弗·哈夫曼-拉罗切有限公司 |
胃肠道脂酶抑制剂的用途
|
|
TR200100471T2
(tr)
*
|
1998-08-14 |
2001-07-23 |
F.Hoffmann-La Roche Ag |
Lipaz inhibitörleri içeren farmasötik bileşimler
|
|
CA2342625A1
(fr)
*
|
1998-09-08 |
2000-03-16 |
Smithkline Beecham Corporation |
Comprimes a base de fibres solubles et d'un derive de lipstatine
|
|
AR025609A1
(es)
*
|
1999-09-13 |
2002-12-04 |
Hoffmann La Roche |
Formulaciones lipidas solidas
|
|
AR025587A1
(es)
*
|
1999-09-13 |
2002-12-04 |
Hoffmann La Roche |
Formulaciones en dispersion que contienen inhibidores de lipasa
|
|
EP1132389A1
(fr)
|
2000-03-06 |
2001-09-12 |
Vernalis Research Limited |
Nouveaux dérivés de l'azaindole pour le traitement de l'obésité
|
|
DE10021618A1
(de)
*
|
2000-05-04 |
2001-11-15 |
Volker Helmstaedter |
Präparat für Darmerkrankungen und dessen Verwendung
|
|
AU2001281846B2
(en)
*
|
2000-06-27 |
2006-04-27 |
Cheplapharm Arzneimittel Gmbh |
Method for preparing a composition
|
|
EP1307263B1
(fr)
|
2000-07-28 |
2005-04-20 |
F. Hoffmann-La Roche Ag |
Nouvelle application d'inhibiteurs de lipase
|
|
NZ523684A
(en)
*
|
2000-07-28 |
2005-04-29 |
F |
New pharmaceutical composition
|
|
CN1323661C
(zh)
|
2000-08-09 |
2007-07-04 |
霍夫曼-拉罗奇有限公司 |
脂酶抑制剂的用途
|
|
US6900226B2
(en)
*
|
2000-09-06 |
2005-05-31 |
Hoffman-La Roche Inc. |
Neuropeptide Y antagonists
|
|
WO2002044152A1
(fr)
|
2000-10-16 |
2002-06-06 |
F. Hoffmann-La Roche Ag |
Derives d'indoline et leur utilisation en tant que ligands de recepteur 5-ht2
|
|
GB0030710D0
(en)
*
|
2000-12-15 |
2001-01-31 |
Hoffmann La Roche |
Piperazine derivatives
|
|
WO2002051844A1
(fr)
|
2000-12-27 |
2002-07-04 |
F. Hoffmann-La Roche Ag |
Derives d'indole et leur utilisation en tant que ligands de recepteurs 5-ht2b et 5-ht2c
|
|
GB0106177D0
(en)
*
|
2001-03-13 |
2001-05-02 |
Hoffmann La Roche |
Piperazine derivatives
|
|
MXPA03010565A
(es)
|
2001-05-21 |
2004-03-02 |
Hoffmann La Roche |
Derivados de quinolina como ligandos para receptor del neuropeptido y.
|
|
US20030027786A1
(en)
*
|
2001-06-06 |
2003-02-06 |
Karsten Maeder |
Lipase inhibiting composition
|
|
US6787558B2
(en)
*
|
2001-09-28 |
2004-09-07 |
Hoffmann-La Roche Inc. |
Quinoline derivatives
|
|
US10285910B2
(en)
|
2001-10-12 |
2019-05-14 |
Aquestive Therapeutics, Inc. |
Sublingual and buccal film compositions
|
|
US20110033542A1
(en)
|
2009-08-07 |
2011-02-10 |
Monosol Rx, Llc |
Sublingual and buccal film compositions
|
|
US8603514B2
(en)
|
2002-04-11 |
2013-12-10 |
Monosol Rx, Llc |
Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
|
|
US7357891B2
(en)
|
2001-10-12 |
2008-04-15 |
Monosol Rx, Llc |
Process for making an ingestible film
|
|
US20190328679A1
(en)
|
2001-10-12 |
2019-10-31 |
Aquestive Therapeutics, Inc. |
Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
|
|
US8900498B2
(en)
|
2001-10-12 |
2014-12-02 |
Monosol Rx, Llc |
Process for manufacturing a resulting multi-layer pharmaceutical film
|
|
US8765167B2
(en)
|
2001-10-12 |
2014-07-01 |
Monosol Rx, Llc |
Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
|
|
US20070281003A1
(en)
|
2001-10-12 |
2007-12-06 |
Fuisz Richard C |
Polymer-Based Films and Drug Delivery Systems Made Therefrom
|
|
US11207805B2
(en)
|
2001-10-12 |
2021-12-28 |
Aquestive Therapeutics, Inc. |
Process for manufacturing a resulting pharmaceutical film
|
|
US8900497B2
(en)
|
2001-10-12 |
2014-12-02 |
Monosol Rx, Llc |
Process for making a film having a substantially uniform distribution of components
|
|
DE10152351B4
(de)
*
|
2001-10-18 |
2005-09-22 |
Schering Ag |
Feste Arzneimittelformulierung für ein Piperazinharnstoffderivat
|
|
WO2003039516A1
(fr)
*
|
2001-11-07 |
2003-05-15 |
Fujisawa Pharmaceuticla Co., Ltd. |
Procede pour ameliorer la dissolution de medicaments a faible pouvoir de dissolution
|
|
WO2003053415A1
(fr)
*
|
2001-12-20 |
2003-07-03 |
Alpex Pharma Sa |
Composition pharmaceutique comprenant de la poudre de lait ecreme
|
|
GB0202015D0
(en)
*
|
2002-01-29 |
2002-03-13 |
Hoffmann La Roche |
Piperazine Derivatives
|
|
BR0307441A
(pt)
*
|
2002-02-04 |
2005-01-04 |
Hoffmann La Roche |
Compostos, processo para a preparação de um composto, composição farmacêutica, utilização desses compostos, método para o tratamento e profilaxia de enfermidades e método para o tratamento de obesidade
|
|
KR100611854B1
(ko)
|
2002-02-28 |
2006-08-11 |
에프. 호프만-라 로슈 아게 |
신경 펩타이드 y(npy) 수용체 길항제로서의 티아졸유도체
|
|
RU2297221C2
(ru)
*
|
2002-04-26 |
2007-04-20 |
Ф.Хоффманн-Ля Рош Аг |
Фармацевтическая композиция, включающая ингибитор липазы и глюкоманнан
|
|
MXPA05000131A
(es)
*
|
2002-07-05 |
2005-04-11 |
Hoffmann La Roche |
Derivados de quinazolina.
|
|
CA2493712A1
(fr)
*
|
2002-08-07 |
2004-02-19 |
F. Hoffmann-La Roche Ag |
Derives d'aminothiazole pouvant servir d'inhibiteurs de recepteur npy5
|
|
NZ537979A
(en)
*
|
2002-09-12 |
2007-08-31 |
Hoffmann La Roche |
N-substituted-1H-indol-5-propionic acid compounds as PPAR agonists useful for the treatment of diabetes
|
|
ATE405560T1
(de)
*
|
2002-11-25 |
2008-09-15 |
Hoffmann La Roche |
Indolderivaten
|
|
US20040178058A1
(en)
*
|
2003-03-10 |
2004-09-16 |
Hsueh-Chung Chen |
Electro-chemical deposition apparatus and method of preventing cavities in an ECD copper film
|
|
GB0314967D0
(en)
*
|
2003-06-26 |
2003-07-30 |
Hoffmann La Roche |
Piperazine derivatives
|
|
RU2006107444A
(ru)
*
|
2003-08-12 |
2007-09-20 |
Ф.Хоффманн-Ля Рош Аг (Ch) |
2-амино-5-бензоилтиазолы в качестве антагонистов npy
|
|
CN100393718C
(zh)
*
|
2003-08-12 |
2008-06-11 |
霍夫曼-拉罗奇有限公司 |
作为npy拮抗剂的噻唑衍生物
|
|
US20060246141A1
(en)
*
|
2005-04-12 |
2006-11-02 |
Elan Pharma International, Limited |
Nanoparticulate lipase inhibitor formulations
|
|
ATE514698T1
(de)
*
|
2005-05-03 |
2011-07-15 |
Hoffmann La Roche |
Tetracyclische azapyrazinoindoline als 5-ht2- liganden
|
|
KR100910000B1
(ko)
*
|
2005-05-13 |
2009-07-29 |
씨제이제일제당 (주) |
리파아제 저해제 함유 약학 조성물
|
|
SI1897558T1
(sl)
*
|
2005-06-09 |
2014-03-31 |
Norgine Bv |
Trden pripravek 2-heksadeciloksi-6-metil-4h-3,1-benzoksazin-e-on
|
|
MX2008002061A
(es)
*
|
2005-08-18 |
2008-04-16 |
Hoffmann La Roche |
Derivados de tiazolil piperidina utiles como moduladores del receptor h3.
|
|
US20070092577A1
(en)
*
|
2005-10-03 |
2007-04-26 |
University Of Tennessee Research Foundation |
Dietary calcium for reducing the production of reactive oxygen species
|
|
DE602006014022D1
(de)
*
|
2005-11-30 |
2010-06-10 |
Hoffmann La Roche |
5-substituierte indol-2-carbonsäureamidderivate
|
|
ATE507222T1
(de)
*
|
2005-11-30 |
2011-05-15 |
Hoffmann La Roche |
1,1-dioxo-thiomorpholinyl-indolyl-methanon- derivate zur verwendung als h3-modulatoren
|
|
RU2008126391A
(ru)
*
|
2005-11-30 |
2010-01-10 |
Ф.Хоффманн-Ля Рош Аг (Ch) |
Производные 1,5-замещенного индол-2-иламида
|
|
JP2009518351A
(ja)
*
|
2005-12-09 |
2009-05-07 |
エフ.ホフマン−ラ ロシュ アーゲー |
肥満症の処置に有用な三環性アミド誘導体
|
|
ATE449776T1
(de)
*
|
2005-12-15 |
2009-12-15 |
Hoffmann La Roche |
Pyrroloä2,3-cüpyridinderivate
|
|
BRPI0619985A2
(pt)
*
|
2005-12-16 |
2011-10-25 |
Hoffmann La Roche |
compostos, processo para a sua manufatura, composições farmacêuticas, métodos para o tratamento e/ou prevenção de enfermidades que estão associadas com a modulação de receptores de h3, de obesidade e de diabetes do tipo ii em um ser humano ou animal e usos dos compostos
|
|
EP1803714A1
(fr)
*
|
2005-12-27 |
2007-07-04 |
KRKA, tovarna zdravil, d.d., Novo mesto |
Procédé de préparation de formes cristallines de orlistat
|
|
AU2007204426A1
(en)
*
|
2006-01-13 |
2007-07-19 |
F. Hoffmann-La Roche Ag |
Cyclohexyl piperazinyl methanone derivatives and their use as histamine H3 receptor modulators
|
|
AU2007206997B2
(en)
*
|
2006-01-23 |
2011-11-24 |
F. Hoffmann-La Roche Ag |
Cyclohexyl sulfonamide derivatives having H3 receptor activity
|
|
US7432255B2
(en)
*
|
2006-05-16 |
2008-10-07 |
Hoffmann-La Roche Inc. |
1H-indol-5-yl-piperazin-1-yl-methanone derivatives
|
|
BRPI0711740A2
(pt)
*
|
2006-05-30 |
2011-12-06 |
Hoffmann La Roche |
compostos, processo para a sua manufatura,composições farmacêuticas que os compreendem, método para o tratamento e/ou prevenção de enfermidades que estão associadas com a modulação de receptores de h3, método para o tratamento ou prevenção de obesidade, de diabetes do tipo ii, e uso dos compostos na manufatura de medicamentos
|
|
EP1872777A1
(fr)
*
|
2006-06-27 |
2008-01-02 |
LEK Pharmaceuticals D.D. |
Composition pharmaceutique contenant de la tetrahydrolipstatin
|
|
US7514433B2
(en)
|
2006-08-03 |
2009-04-07 |
Hoffmann-La Roche Inc. |
1H-indole-6-yl-piperazin-1-yl-methanone derivatives
|
|
US20080146559A1
(en)
|
2006-12-08 |
2008-06-19 |
Li Chen |
4,5,6,7-Tetrahydro-Thieno [2,3-C] Pyridine Derivatives
|
|
TR200607613A2
(tr)
*
|
2006-12-29 |
2008-07-21 |
NOBEL İLAÇ SAN.ve TiC.A.Ş. |
Lipaz inhibitörü içeren farmasötik formülasyonlar
|
|
EP2002825B1
(fr)
*
|
2007-06-14 |
2013-05-22 |
Krka |
Compositions pharmaceutiques comportant de l'orlistat
|
|
EA201070378A1
(ru)
*
|
2007-09-17 |
2010-08-30 |
Др. Редди`С Лабораторис Лтд. |
Фармацевтические составы орлистата
|
|
WO2009044380A2
(fr)
|
2007-10-05 |
2009-04-09 |
Ranbaxy Laboratories Limited |
Formulations contenant des particules d'orlistat à dimension de particule contrôlée
|
|
US20100317642A1
(en)
*
|
2007-10-15 |
2010-12-16 |
Inventis Dds Pvt Limited |
Pharmaceutical composition of orlistat
|
|
US8298583B2
(en)
*
|
2007-10-19 |
2012-10-30 |
Monosol Rx, Llc |
Film delivery system for tetrahydrolipstatin
|
|
US20090220593A1
(en)
*
|
2008-01-29 |
2009-09-03 |
Gulati Inder |
Extended release dosage forms of quetiapine
|
|
PL216542B1
(pl)
|
2008-03-20 |
2014-04-30 |
Zakłady Farmaceutyczne POLPHARMA Spółka Akcyjna |
Sposób wytwarzania stabilnej kompozycji orlistatu w postaci kapsułkowanego proszku
|
|
WO2010042499A1
(fr)
*
|
2008-10-06 |
2010-04-15 |
Banner Pharmacaps, Inc. |
Solutions stables d'orlistat pour formes galéniques pharmaceutiques
|
|
BRPI0901602B8
(pt)
*
|
2009-04-03 |
2021-05-25 |
Ems S/A |
formulação farmacêuticas
|
|
MX342962B
(es)
|
2009-09-18 |
2016-06-07 |
Teva Pharmaceuticals Holdings Mexico S A De C V |
Composicion farmaceutica para bajar de peso y procedimiento para obtener la misma.
|
|
UA107369C2
(en)
|
2010-02-01 |
2014-12-25 |
Lab Bago S A |
Pharmaceutical composition with anti-obesity activity comprising a premixture of pure orlistat and preparation process
|
|
RU2441654C2
(ru)
*
|
2010-02-17 |
2012-02-10 |
Лабораториос Баго С.А. |
Фармацевтическая композиция с активностью против ожирения, включающая премикс чистого орлистата, и способ ее изготовления
|
|
US20120040008A1
(en)
|
2010-08-11 |
2012-02-16 |
Ashish Chatterji |
Pharmaceutical compositions of metabotropic glutamate 5 receptor (mglu5) antagonists
|
|
US20120039999A1
(en)
|
2010-08-11 |
2012-02-16 |
Ashish Chatterji |
Pharmaceutical compositions of metabotropic glutamate 5 receptor (mglu5) antagonists
|
|
US9149959B2
(en)
|
2010-10-22 |
2015-10-06 |
Monosol Rx, Llc |
Manufacturing of small film strips
|
|
PL2720723T3
(pl)
*
|
2011-06-15 |
2018-10-31 |
Synthon Bv |
Stabilizowana kompozycja worykonazolu
|
|
US8623924B2
(en)
|
2011-07-15 |
2014-01-07 |
Nusirt Sciences, Inc. |
Compositions and methods for modulating metabolic pathways
|
|
CN102362863B
(zh)
*
|
2011-11-21 |
2013-06-12 |
山东新时代药业有限公司 |
一种含奥利司他的制剂及其制备方法
|
|
GB201122213D0
(en)
*
|
2011-12-23 |
2012-02-01 |
Norgine Bv |
Compositions
|
|
AU2012101841A4
(en)
*
|
2011-12-23 |
2013-01-17 |
Norgine Bv |
Compositions comprising cetilistat
|
|
WO2013092786A1
(fr)
|
2011-12-23 |
2013-06-27 |
Norgine B.V. |
Compositions comprenant du cetilistat
|
|
US9198454B2
(en)
|
2012-03-08 |
2015-12-01 |
Nusirt Sciences, Inc. |
Compositions, methods, and kits for regulating energy metabolism
|
|
MX2014010926A
(es)
*
|
2012-03-13 |
2015-04-10 |
Piramal Entpr Ltd |
Composicion herbaria para el tratamiento de transtornos metabolicos.
|
|
MX2015006023A
(es)
|
2012-11-13 |
2016-03-31 |
Nusirt Sciences Inc |
Composiciones y metodos para incrementar el metabolismo energetico.
|
|
DE202012104963U1
(de)
|
2012-12-19 |
2013-01-14 |
Norgine B.V. |
Cetilistat aufweisende Zusammensetzungen
|
|
CN105228627B
(zh)
|
2013-03-15 |
2018-07-13 |
纽斯尔特科学公司 |
亮氨酸和烟酸降低脂质水平
|
|
CN104740637A
(zh)
*
|
2013-12-31 |
2015-07-01 |
北京科信必成医药科技发展有限公司 |
一种稳定的奥利司他口服制剂及其制备方法
|
|
EP3110507B1
(fr)
|
2014-02-27 |
2020-11-18 |
NuSirt Sciences, Inc. |
Compositions et procédés permettant la réduction ou la prévention de stéatose hépatique
|
|
US10743813B2
(en)
|
2014-09-11 |
2020-08-18 |
Rattan Nath |
Diabetes control using postprandial feedback
|
|
US11273131B2
(en)
|
2016-05-05 |
2022-03-15 |
Aquestive Therapeutics, Inc. |
Pharmaceutical compositions with enhanced permeation
|
|
KR20230137362A
(ko)
|
2016-05-05 |
2023-10-04 |
어퀘스티브 테라퓨틱스, 아이엔씨. |
강화된 전달 에프네프린 조성물
|
|
US12427121B2
(en)
|
2016-05-05 |
2025-09-30 |
Aquestive Therapeutics, Inc. |
Enhanced delivery epinephrine compositions
|
|
US12433850B2
(en)
|
2016-05-05 |
2025-10-07 |
Aquestive Therapeutics, Inc. |
Enhanced delivery epinephrine and prodrug compositions
|
|
CN108785272B
(zh)
*
|
2018-09-04 |
2019-04-09 |
中山万汉制药有限公司 |
一种奥利司他软胶囊及其制备方法
|
|
CN115105476B
(zh)
*
|
2021-03-23 |
2023-11-14 |
山东新时代药业有限公司 |
一种奥利司他冻干口服制剂及其制备工艺
|
|
EP4422607A4
(fr)
|
2021-10-25 |
2025-09-03 |
Aquestive Therapeutics Inc |
Compositions orales et nasales et méthodes de traitement
|
|
CN115300479A
(zh)
*
|
2022-08-23 |
2022-11-08 |
宁波高新区美诺华医药创新研究院有限公司 |
奥利司他胶囊制备方法
|