MA24683A1 - Formes polymorphes de dofetilide, procede pour leur preparation et composition les contenant. - Google Patents
Formes polymorphes de dofetilide, procede pour leur preparation et composition les contenant.Info
- Publication number
- MA24683A1 MA24683A1 MA25313A MA25313A MA24683A1 MA 24683 A1 MA24683 A1 MA 24683A1 MA 25313 A MA25313 A MA 25313A MA 25313 A MA25313 A MA 25313A MA 24683 A1 MA24683 A1 MA 24683A1
- Authority
- MA
- Morocco
- Prior art keywords
- dofetilide
- preparation
- composition containing
- polymorphic forms
- compositions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- IXTMWRCNAAVVAI-UHFFFAOYSA-N dofetilide Chemical compound C=1C=C(NS(C)(=O)=O)C=CC=1CCN(C)CCOC1=CC=C(NS(C)(=O)=O)C=C1 IXTMWRCNAAVVAI-UHFFFAOYSA-N 0.000 title abstract 2
- 229960002994 dofetilide Drugs 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000019622 heart disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
L'INVENTION CONCERNE LES FORMES POLYMORPHES DE DOFÉTILIDE PRATIQUEMENT PURES P162, P162A ET P143. ELLE CONCERNE ÉGALEMENT UN PROCÉDÉ POUR LEUR PRÉPARATION, ET DES COMPOSITIONS LES CONTENANT. APPLICATION : UTILISATION DE CES COMPOSÉS ET COMPOSITIONS DANS LE TRAITEMENT DE MALADIES CARDIAQUES.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9722662.5A GB9722662D0 (en) | 1997-10-27 | 1997-10-27 | Polymorphs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA24683A1 true MA24683A1 (fr) | 1999-07-01 |
Family
ID=10821150
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA25313A MA24683A1 (fr) | 1997-10-27 | 1998-10-26 | Formes polymorphes de dofetilide, procede pour leur preparation et composition les contenant. |
Country Status (46)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10019067C1 (de) * | 2000-04-18 | 2001-10-04 | Lohmann Therapie Syst Lts | Transdermales Therapeutisches System zur Abgabe von Dofetilid und seine Verwendung |
| US7326772B2 (en) * | 2005-05-12 | 2008-02-05 | Penta Biotech, Inc. | Peptide for assaying hERG channel binding |
| CZ2017772A3 (cs) | 2017-12-01 | 2019-05-29 | Farmak, A.S. | Způsob přípravy N-[4-(2-{[2-(4-methansulfonamidofenoxy)ethyl](methyl)amino}ethyl)fenyl]methansulfonamidu (Dofetilidu) |
| US10512620B1 (en) | 2018-08-14 | 2019-12-24 | AltaThera Pharmaceuticals, LLC | Method of initiating and escalating sotalol hydrochloride dosing |
| US11696902B2 (en) | 2018-08-14 | 2023-07-11 | AltaThera Pharmaceuticals, LLC | Method of initiating and escalating sotalol hydrochloride dosing |
| US12396970B2 (en) | 2021-08-20 | 2025-08-26 | AltaThera Pharmaceuticals LLC | Anti-arrhythmic compositions and methods |
| US11344518B2 (en) | 2018-08-14 | 2022-05-31 | AltaThera Pharmaceuticals LLC | Method of converting atrial fibrillation to normal sinus rhythm and loading oral sotalol in a shortened time frame |
| US11610660B1 (en) | 2021-08-20 | 2023-03-21 | AltaThera Pharmaceuticals LLC | Antiarrhythmic drug dosing methods, medical devices, and systems |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EG18188A (en) * | 1986-05-01 | 1992-09-30 | Pfizer Ltd | Process for preparation anti-arhythmia agents |
| EP0898964A1 (fr) * | 1997-08-19 | 1999-03-03 | Pfizer Inc. | Traitement de la défaillance cardiaque |
-
1997
- 1997-10-27 GB GBGB9722662.5A patent/GB9722662D0/en not_active Ceased
-
1998
- 1998-09-10 UA UA2000042087A patent/UA67755C2/uk unknown
- 1998-10-08 TW TW087116747A patent/TW449589B/zh not_active IP Right Cessation
- 1998-10-09 AT AT98965638T patent/ATE232199T1/de not_active IP Right Cessation
- 1998-10-09 ID IDW20000767A patent/ID24658A/id unknown
- 1998-10-09 DK DK98965638T patent/DK1027329T3/da active
- 1998-10-09 US US09/423,986 patent/US6124363A/en not_active Expired - Lifetime
- 1998-10-09 HR HR970680A patent/HRP20000247B1/xx not_active IP Right Cessation
- 1998-10-09 SK SK586-2000A patent/SK5862000A3/sk unknown
- 1998-10-09 BR BR9813308-0A patent/BR9813308A/pt not_active Application Discontinuation
- 1998-10-09 NZ NZ503785A patent/NZ503785A/en unknown
- 1998-10-09 WO PCT/EP1998/006641 patent/WO1999021829A1/fr not_active Ceased
- 1998-10-09 CN CNB988106213A patent/CN1146537C/zh not_active Expired - Fee Related
- 1998-10-09 IL IL13543598A patent/IL135435A0/xx not_active IP Right Cessation
- 1998-10-09 EA EA200000365A patent/EA002656B1/ru not_active IP Right Cessation
- 1998-10-09 AU AU21512/99A patent/AU737668B2/en not_active Ceased
- 1998-10-09 PL PL340805A patent/PL197379B1/pl unknown
- 1998-10-09 CA CA002307121A patent/CA2307121C/fr not_active Expired - Fee Related
- 1998-10-09 ES ES98965638T patent/ES2190620T3/es not_active Expired - Lifetime
- 1998-10-09 JP JP2000517941A patent/JP3569495B2/ja not_active Expired - Fee Related
- 1998-10-09 TR TR2000/01135T patent/TR200001135T2/xx unknown
- 1998-10-09 SI SI9830347T patent/SI1027329T1/xx unknown
- 1998-10-09 YU YU24000A patent/YU24000A/sh unknown
- 1998-10-09 KR KR10-2000-7004471A patent/KR100366167B1/ko not_active Expired - Fee Related
- 1998-10-09 DE DE69811256T patent/DE69811256T2/de not_active Expired - Fee Related
- 1998-10-09 HU HU0004735A patent/HUP0004735A3/hu unknown
- 1998-10-09 PT PT98965638T patent/PT1027329E/pt unknown
- 1998-10-09 EP EP98965638A patent/EP1027329B1/fr not_active Expired - Lifetime
- 1998-10-22 AP APAP/P/1998/001371A patent/AP906A/en active
- 1998-10-22 PA PA19988462001A patent/PA8462001A1/es unknown
- 1998-10-23 MY MYPI98004829A patent/MY123352A/en unknown
- 1998-10-23 PE PE1998001003A patent/PE122199A1/es not_active Application Discontinuation
- 1998-10-23 AR ARP980105310A patent/AR015193A1/es unknown
- 1998-10-26 TN TNTNSN98193A patent/TNSN98193A1/fr unknown
- 1998-10-26 UY UY25222A patent/UY25222A1/es not_active IP Right Cessation
- 1998-10-26 MA MA25313A patent/MA24683A1/fr unknown
- 1998-10-26 HN HN1998000165A patent/HN1998000165A/es unknown
- 1998-10-26 ZA ZA9809719A patent/ZA989719B/xx unknown
- 1998-10-26 DZ DZ980242A patent/DZ2632A1/fr active
- 1998-10-27 GT GT199800165A patent/GT199800165A/es unknown
- 1998-10-27 CO CO98062885A patent/CO4970768A1/es unknown
- 1998-11-28 SA SA98190834A patent/SA98190834B1/ar unknown
-
1999
- 1999-01-08 UY UY25341A patent/UY25341A1/es not_active IP Right Cessation
-
2000
- 2000-03-31 IS IS5426A patent/IS2179B/is unknown
- 2000-04-20 OA OA1200000117A patent/OA11350A/en unknown
- 2000-04-24 BG BG104373A patent/BG64125B1/bg unknown
- 2000-04-27 NO NO20002191A patent/NO325630B1/no not_active IP Right Cessation
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