MA25325A1 - Nouvelle gelule a dosage controle, la methode de production et la formulation des unites multiples qui la contiennent. - Google Patents

Nouvelle gelule a dosage controle, la methode de production et la formulation des unites multiples qui la contiennent.

Info

Publication number
MA25325A1
MA25325A1 MA26228A MA26228A MA25325A1 MA 25325 A1 MA25325 A1 MA 25325A1 MA 26228 A MA26228 A MA 26228A MA 26228 A MA26228 A MA 26228A MA 25325 A1 MA25325 A1 MA 25325A1
Authority
MA
Morocco
Prior art keywords
formulation
production method
same
multiple units
units containing
Prior art date
Application number
MA26228A
Other languages
English (en)
Inventor
Anders Ringberg
Torkel Gren
Martin Wikberg
Randy J Wald
Original Assignee
Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20413266&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA25325(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from PCT/SE1999/001463 external-priority patent/WO2000012069A1/fr
Application filed by Pharmacia Ab filed Critical Pharmacia Ab
Publication of MA25325A1 publication Critical patent/MA25325A1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MA26228A 1998-11-11 2001-06-08 Nouvelle gelule a dosage controle, la methode de production et la formulation des unites multiples qui la contiennent. MA25325A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9803871A SE9803871D0 (sv) 1998-11-11 1998-11-11 Therapeutic method and formulation
PCT/SE1999/001463 WO2000012069A1 (fr) 1998-08-27 1999-08-26 Formulation de tolterodine therapeutique a liberation controlee

Publications (1)

Publication Number Publication Date
MA25325A1 true MA25325A1 (fr) 2001-12-31

Family

ID=20413266

Family Applications (1)

Application Number Title Priority Date Filing Date
MA26228A MA25325A1 (fr) 1998-11-11 2001-06-08 Nouvelle gelule a dosage controle, la methode de production et la formulation des unites multiples qui la contiennent.

Country Status (40)

Country Link
US (1) US6911217B1 (fr)
EP (1) EP1128819B1 (fr)
JP (1) JP3616011B2 (fr)
KR (1) KR100467384B1 (fr)
CN (1) CN1169522C (fr)
AP (1) AP1323A (fr)
AR (1) AR027815A1 (fr)
AT (1) ATE247458T1 (fr)
AU (1) AU762410B2 (fr)
BG (1) BG65149B1 (fr)
BR (1) BRPI9915142B8 (fr)
CA (1) CA2350061C (fr)
CZ (1) CZ299582B6 (fr)
DE (1) DE69910604T2 (fr)
DK (1) DK1128819T3 (fr)
EA (1) EA005074B1 (fr)
EE (1) EE05232B1 (fr)
ES (1) ES2204193T3 (fr)
GE (1) GEP20022833B (fr)
HK (1) HK1040917B (fr)
HR (1) HRP20010333B1 (fr)
HU (1) HU226582B1 (fr)
ID (1) ID30039A (fr)
IL (1) IL142809A0 (fr)
IS (1) IS2370B (fr)
MA (1) MA25325A1 (fr)
MY (1) MY122195A (fr)
NO (1) NO331399B1 (fr)
NZ (1) NZ511430A (fr)
OA (1) OA11673A (fr)
PL (1) PL195780B1 (fr)
PT (1) PT1128819E (fr)
RS (1) RS49891B (fr)
SE (1) SE9803871D0 (fr)
SI (1) SI1128819T1 (fr)
SK (1) SK284758B6 (fr)
TW (2) TWI222879B (fr)
UA (1) UA57165C2 (fr)
WO (1) WO2000027364A1 (fr)
ZA (1) ZA200103575B (fr)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998003067A1 (fr) * 1996-07-19 1998-01-29 Gunnar Aberg S(-)-tolterodine pour le traitement des troubles urinaires et gastro-intestinaux
US8563522B2 (en) 1997-07-08 2013-10-22 The Iams Company Method of maintaining and/or attenuating a decline in quality of life
EP0957073A1 (fr) 1998-05-12 1999-11-17 Schwarz Pharma Ag Dérivés de 3,3-diphénylpropylamines
HUP0203028A3 (en) 1999-11-11 2005-07-28 Pharmacia Ab Pharmaceutical formulation containing tolterodine and its use
US7101888B2 (en) * 2002-08-28 2006-09-05 Pharmacia & Upjohn Company Oral liquid tolterodine composition
US8168170B2 (en) 2002-10-03 2012-05-01 The Procter And Gamble Company Compositions having an inner core and at least three surrounding layers
MXPA05007767A (es) * 2003-01-22 2006-01-31 Pfizer Health Ab Dosis reducida de tolterodina y otros agentes antimuscarinicos para tratar trastornos urinarios.
DE10315917A1 (de) * 2003-04-08 2004-11-18 Schwarz Pharma Ag Hochreine Basen von 3,3-Diphenylpropylaminmonoestern
US8802139B2 (en) 2003-06-26 2014-08-12 Intellipharmaceutics Corp. Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
US8709476B2 (en) 2003-11-04 2014-04-29 Supernus Pharmaceuticals, Inc. Compositions of quaternary ammonium compounds containing bioavailability enhancers
DE602004030931D1 (fr) 2003-11-04 2011-02-17 Supernus Pharmaceuticals Inc
US8894991B2 (en) 2003-12-19 2014-11-25 The Iams Company Canine probiotic Lactobacilli
US8877178B2 (en) 2003-12-19 2014-11-04 The Iams Company Methods of use of probiotic bifidobacteria for companion animals
US7785635B1 (en) 2003-12-19 2010-08-31 The Procter & Gamble Company Methods of use of probiotic lactobacilli for companion animals
US20050152884A1 (en) 2003-12-19 2005-07-14 The Procter & Gamble Company Canine probiotic Bifidobacteria globosum
US20050158294A1 (en) 2003-12-19 2005-07-21 The Procter & Gamble Company Canine probiotic Bifidobacteria pseudolongum
US8394409B2 (en) * 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
EP1629834A1 (fr) 2004-08-27 2006-03-01 KRKA, D.D., Novo Mesto Composition pharmaceutique de tolterodine avec liberation soutenue
JP2007527923A (ja) * 2005-01-10 2007-10-04 テバ ファーマシューティカル インダストリーズ リミティド トルテロジンタルトレートの調製方法
AU2006253007B2 (en) 2005-05-31 2012-12-20 Alimentary Health Ltd Feline probiotic Bifidobacteria
EP2261323A1 (fr) 2005-05-31 2010-12-15 The Iams Company Lactobacilles probiotiques félins
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
EP2997953B1 (fr) 2006-01-18 2018-12-26 Intec Pharma Ltd. Dispositif d'administration par voie orale d'un agent
ES2593047T3 (es) 2006-02-03 2016-12-05 Opko Renal, Llc Tratamiento de la insuficiencia y deficiencia de vitamina D con 25-hidroxivitamina D2 y 25-hidroxivitamina D3
KR100714058B1 (ko) * 2006-02-06 2007-05-02 한국유나이티드제약 주식회사 톨테로딘 엘-주석산염의 서방형 경구투여 조성물 및 이의 제조 방법
US20070202172A1 (en) * 2006-02-24 2007-08-30 Tomer Gold Metoprolol succinate E.R. tablets and methods for their preparation
CA2645940A1 (fr) * 2006-03-21 2007-09-27 Teva Pharmaceutical Industries Ltd. Formule a liberation controlee de tolterodine
EP1839649A1 (fr) * 2006-03-31 2007-10-03 LEK Pharmaceuticals D.D. Formulations enrobées pour tolterodine
JP5457830B2 (ja) * 2006-04-03 2014-04-02 オディディ,イサ オルガノゾル被膜を含む制御放出送達デバイス
EP2015735A1 (fr) * 2006-04-21 2009-01-21 Synthon B.V. Perles de tolterodine
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
WO2007131804A1 (fr) 2006-05-17 2007-11-22 Synthon B.V. Composition en comprimé pour la libération prolongée de la tamsulosine
ES2670029T3 (es) 2006-06-21 2018-05-29 Opko Ireland Global Holdings, Ltd. Terapia usando agente de repleción de la vitamina D y agente de reemplazo de la hormona de la vitamina D
JP2008007458A (ja) * 2006-06-29 2008-01-17 Freunt Ind Co Ltd レイヤリング用核粒子とその製造方法
EP2591675A1 (fr) 2006-11-27 2013-05-15 H. Lundbeck A/S Dérivés d'hétéroaryle et d'amide
RU2436581C2 (ru) 2007-02-01 2011-12-20 Дзе Иамс Компани Способ уменьшения воспаления и снижения стресса у млекопитающего
US11752158B2 (en) 2007-04-25 2023-09-12 Eirgen Pharma Ltd. Method of treating vitamin D insufficiency and deficiency
HUE073014T2 (hu) 2007-04-25 2025-12-28 Opko Renal Llc Eljárás a másodlagos hyperparathyreoidismus biztonságos és hatékony kezelésére és megelõzésére krónikus vesebetegség esetén
KR20190028822A (ko) 2007-04-25 2019-03-19 사이토크로마 인코포레이티드 비타민 d 화합물과 밀랍성 담체를 포함하는 경구 조절성 방출 조성물
CL2008001970A1 (es) * 2007-07-03 2009-03-27 Synthon Bv Perla con un nucleo de celulosa microcristalina, un recubrimiento soluble en agua con un polimero vinil pirrolidina, una capa con tolterodina y un aglutinante, y una capa de liberacion controlada con un poliacrilato; proceso para prepararla; forma de dosificacion, util en trastornos urinarios como vejiga hiperactiva.
US8110226B2 (en) * 2007-07-20 2012-02-07 Mylan Pharmaceuticals Inc. Drug formulations having inert sealed cores
US8486452B2 (en) 2007-07-20 2013-07-16 Mylan Pharmaceuticals Inc. Stabilized tolterodine tartrate formulations
EP2175843B1 (fr) * 2007-08-08 2014-10-08 Inventia Healthcare Private Limited Compositions à libération prolongée comprenant de la toltérodine
AU2008286914B2 (en) * 2007-08-13 2014-10-02 Ohemo Life Sciences Inc. Abuse resistant drugs, method of use and method of making
US20090192228A1 (en) * 2008-01-28 2009-07-30 Actavis Group Ptc Ehf Controlled-Release Tolterodine Compositions and Methods
US20090214665A1 (en) * 2008-02-26 2009-08-27 Lai Felix S Controlled Release Muscarinic Receptor Antagonist Formulation
CA2629099A1 (fr) * 2008-04-01 2009-10-01 Pharmascience Inc. Nouvelles formulations pharmaceutiques orales a liberation controlee
EP2281058B1 (fr) 2008-04-02 2016-06-29 Opko Ireland Global Holdings, Ltd. Procédés, compositions, utilisations, et kits utiles pour la carence en vitamine d et des troubles associés
WO2009140557A2 (fr) * 2008-05-14 2009-11-19 Capricorn Pharma, Inc. Formulations de toltérodine à libération modifiée
US9771199B2 (en) 2008-07-07 2017-09-26 Mars, Incorporated Probiotic supplement, process for making, and packaging
US8465770B2 (en) 2008-12-24 2013-06-18 Synthon Bv Low dose controlled release tablet
US9078830B2 (en) 2009-07-31 2015-07-14 Ranbaxy Laboratories Limited Multi-layered, multiple unit pharmaceutical compositions
US10104903B2 (en) 2009-07-31 2018-10-23 Mars, Incorporated Animal food and its appearance
WO2011061616A2 (fr) 2009-11-23 2011-05-26 Micro Labs Limited Compositions à libération prolongée contenant de la toltérodine et procédé de préparation de celles-ci
WO2011095388A1 (fr) 2010-02-04 2011-08-11 Synthon Bv Microgranule de toltérodine
JO3112B1 (ar) 2010-03-29 2017-09-20 Ferring Bv تركيبة دوائية سريعة التحلل
NZ706991A (en) 2010-03-29 2016-08-26 Ferring Bv A fast dissolving pharmaceutical composition
WO2011123476A1 (fr) 2010-03-29 2011-10-06 Cytochroma Inc. Procédés et compositions pour réduction de taux d'hormone parathyroïde
WO2011137054A1 (fr) 2010-04-30 2011-11-03 Merck Sharp & Dohme Corp. Nouveaux agonistes du récepteur bêta 3 adrénergique
US20120040008A1 (en) * 2010-08-11 2012-02-16 Ashish Chatterji Pharmaceutical compositions of metabotropic glutamate 5 receptor (mglu5) antagonists
US20120289560A1 (en) * 2011-05-10 2012-11-15 Theravida, Inc. Combinations of tolterodine and salivary stimulants for the treatment of overactive bladder
GR1007628B (el) 2011-07-27 2012-06-29 Φαρματεν Αβεε, Φαρμακευτικο σκευασμα περιεχον εναν αντιμουσκαρινικο παραγοντα και μεθοδος για την παρασκευη αυτου
RU2633640C2 (ru) 2011-09-16 2017-10-16 Ферринг Б.В. Быстрорастворимая фармацевтическая композиция
WO2013047795A1 (fr) * 2011-09-30 2013-04-04 アステラス製薬株式会社 Composition pharmaceutique granulaire
CA2878784A1 (fr) 2012-07-12 2014-01-16 Ferring B.V. Formulations de diclofenac
JP2015529255A (ja) * 2012-09-20 2015-10-05 オーエイチアール ファーマ, エルエルシーOhr Pharma, Llc 治療薬の持続放出のための多層の生体分解可能なマイクロ粒子
TW201422254A (zh) 2012-11-21 2014-06-16 Ferring Bv 用於速釋及延釋的組成物
US20150306170A1 (en) * 2012-11-21 2015-10-29 Ferring B.V. Composition for immediate and extended release
WO2014159051A1 (fr) * 2013-03-13 2014-10-02 Advanced Bionutrition Corp. Substances bioactives stables et procédés de fabrication
US20140275149A1 (en) 2013-03-15 2014-09-18 Inspirion Delivery Technologies, Llc Abuse deterrent compositions and methods of use
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 d 방출 제형
AU2014246617A1 (en) 2013-12-23 2015-07-09 Sun Pharmaceutical Industries Limited Multi-layered, multiple unit pharmaceutical compositions
US10220047B2 (en) 2014-08-07 2019-03-05 Opko Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
US10729685B2 (en) 2014-09-15 2020-08-04 Ohemo Life Sciences Inc. Orally administrable compositions and methods of deterring abuse by intranasal administration
CA2936740C (fr) * 2014-10-31 2017-10-10 Purdue Pharma Methodes et compositions destinees au traitement du trouble de deficit d'attention
JP6924177B2 (ja) * 2016-02-23 2021-08-25 ニプロ株式会社 医薬組成物粒子とそれを含む口腔内崩壊製剤
JP7032322B2 (ja) 2016-03-28 2022-03-08 オプコ アイルランド グローバル ホールディングス リミテッド ビタミンd治療法
US12303604B1 (en) 2024-10-16 2025-05-20 Currax Pharmaceuticals Llc Pharmaceutical formulations comprising naltrexone and/or bupropion

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1144911B (it) * 1981-03-19 1986-10-29 Pharmatec Spa Composizione farmaceutica a rilascio controllato contenente ibuprofen
JPH07107450A (ja) 1993-10-08 1995-04-21 Hitachi Ltd 情報通信装置
JP3453186B2 (ja) 1994-04-14 2003-10-06 共和薬品工業株式会社 徐放性マイクロカプセルおよびその製造方法
SE9402422D0 (sv) * 1994-07-08 1994-07-08 Astra Ab New beads for controlled release and a pharmaceutical preparation containing the same
US5645858A (en) * 1994-10-06 1997-07-08 Ortho Pharmaceutical Corporation Multilayered controlled release pharmaceutical dosage form
US5567441A (en) * 1995-03-24 1996-10-22 Andrx Pharmaceuticals Inc. Diltiazem controlled release formulation
WO1998003067A1 (fr) 1996-07-19 1998-01-29 Gunnar Aberg S(-)-tolterodine pour le traitement des troubles urinaires et gastro-intestinaux
US6312728B1 (en) * 1998-07-07 2001-11-06 Cascade Development, Inc. Sustained release pharmaceutical preparation

Also Published As

Publication number Publication date
NZ511430A (en) 2003-05-30
HRP20010333A2 (en) 2003-04-30
BR9915142A (pt) 2001-08-07
ATE247458T1 (de) 2003-09-15
BG65149B1 (bg) 2007-04-30
SK6252001A3 (en) 2002-01-07
SE9803871D0 (sv) 1998-11-11
HRP20010333B1 (en) 2004-10-31
IS2370B (is) 2008-06-15
CN1169522C (zh) 2004-10-06
CZ299582B6 (cs) 2008-09-10
BRPI9915142B1 (pt) 2015-08-25
TWI222879B (en) 2004-11-01
HU226582B1 (en) 2009-04-28
HUP0105038A2 (en) 2002-06-29
OA11673A (en) 2005-01-12
IL142809A0 (en) 2002-03-10
HK1040917B (zh) 2005-05-27
BG105582A (en) 2001-12-29
EE200100254A (et) 2002-12-16
UA57165C2 (uk) 2003-06-16
TWI267385B (en) 2006-12-01
DE69910604T2 (de) 2004-06-24
MY122195A (en) 2006-03-31
ES2204193T3 (es) 2004-04-16
US6911217B1 (en) 2005-06-28
AR027815A1 (es) 2003-04-16
KR100467384B1 (ko) 2005-01-24
CA2350061C (fr) 2005-05-17
AP2001002166A0 (en) 2001-06-30
SI1128819T1 (en) 2003-12-31
WO2000027364A1 (fr) 2000-05-18
PL348612A1 (en) 2002-06-03
YU33101A (sh) 2003-10-31
AU1436600A (en) 2000-05-29
HUP0105038A3 (en) 2006-07-28
EP1128819B1 (fr) 2003-08-20
GEP20022833B (en) 2002-11-25
HK1040917A1 (en) 2002-06-28
EA005074B1 (ru) 2004-10-28
EP1128819A1 (fr) 2001-09-05
NO331399B1 (no) 2011-12-19
CZ20011627A3 (cs) 2001-10-17
CN1326339A (zh) 2001-12-12
EA200100538A1 (ru) 2001-10-22
JP2003517446A (ja) 2003-05-27
EE05232B1 (et) 2009-12-15
ID30039A (id) 2001-11-01
BRPI9915142B8 (pt) 2021-05-25
SK284758B6 (sk) 2005-11-03
CA2350061A1 (fr) 2000-05-18
RS49891B (sr) 2008-08-07
ZA200103575B (en) 2002-05-03
DK1128819T3 (da) 2003-12-01
PT1128819E (pt) 2003-12-31
AP1323A (en) 2004-11-05
NO20012314L (no) 2001-07-09
DE69910604D1 (de) 2003-09-25
JP3616011B2 (ja) 2005-02-02
IS5936A (is) 2001-05-09
KR20010075695A (ko) 2001-08-09
NO20012314D0 (no) 2001-05-10
AU762410B2 (en) 2003-06-26
PL195780B1 (pl) 2007-10-31

Similar Documents

Publication Publication Date Title
MA25325A1 (fr) Nouvelle gelule a dosage controle, la methode de production et la formulation des unites multiples qui la contiennent.
NO993519L (no) Fenofibrat farmasöytisk blanding som har höy biotilgjengelighet og fremgangsmÕte for fremstilling av den
NO973922L (no) Nye taxoider, deres fremstilling og farmasöytiske preparater inneholdende forbindelsene
MXPA03007712A (es) Sales farmaceuticas.
EE9700044A (et) Heteroarüüloksasolidinoonid, nende valmistamismeetod, kasutamine ravimite valmistamiseks ja nimetatud ühendeid sisaldavad ravimid.
DE69102531D1 (de) Mikrokapseln, Verkapselungsverfahren und Methode zur Anwendung derselben.
ZA965752B (en) Triphenylethylenes, process for their production, pharmaceutical preparations that contain these triphenylethylenes as well as their use for the production of pharmaceutical agents.
NO20031273D0 (no) Substituerte kanelsyreguanidiner, fremgangsmåte for deres fremstilling, deres anvendelse som legemiddel og legemiddel som inneholder de samme
FI954111L (fi) Uudet taksoidit, niiden valmistus ja niitä sisältävät farmaseuttiset valmisteet
FI943688L (fi) Uudet 11-bentsaldoksiimi-17beta-metoksi-27alfa-metoksi-metyyli-estradieenijohdannaiset, menetelmät niiden valmistamiseksi ja näitä sisältävät lääkeaineet
HUP9800273A3 (en) Benzothiazine dioxides as endothelin antagonists, process for their production and pharmaceutical compositions containing the same
WO2001058875A3 (fr) Derives substitues d'acide 1,2,3,4-tetrahydroquinoline-2-carboxylique
NO883465L (no) Fremgangsmaate og mellomprodukter for fremstilling av 1-fenyl-3-(1-piperazinyl)-1h-indazoler, og anvendelse derav som medikamenter.
FI970095A7 (fi) Uudet kemialliset yhdisteet, niiden valmistus ja niiden käyttö lääkeai neena
NO306156B1 (no) Substituerte benzyloksykarbonylguanidiner, deres anvendelse til fremstilling av medikament eller diagnostikum sÕvel som legemidler inneholdende disse
FI961938L (fi) Uudet taksoidit, niiden valmistus ja niitä sisältävät farmaseuttiset valmisteet
FI951631L (fi) Substituoituja kynureniinejä, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeinä
NO960272D0 (no) Oksatiolaner, fremgangsmåte for deres fremstilling og farmasöytiske preparater som inneholder de samme
ZA988711B (en) New tetracycles, process for their production and pharmaceutical preparations containing these compounds.
IL117943A0 (en) Dihalopropene compounds, insecticides containing them as active ingredients and intermediates for their production
NO904576D0 (no) Aminopyridinylaminofenol og beslektede forbindelser, mellomprodukter, fremgangsmaate for deres fremstilling og anvendelse som medikamenter.
HUP9802731A3 (en) Vitamin d analogues, use thereof, medicaments containing them, their production
ATE125541T1 (de) Reine kristalline form von rifapentin.
HUP9801068A2 (hu) 1,2,3,4-Tetrahidro-2-naftil-amin-származékok, ezek előállítása és alkalmazása, valamint ilyen származékokat tartalmazó gyógyászati készítmények
NO903347L (no) 14,17alfa-ethano- og ethanooestratriener, fremgangsmaate forfremstilling av disse forbindelser, saavel som anvendelse av dem for fremstilling av legemidler.