MA26906A1 - Aminoalkyl 1-lactames substituees et leur utilisation en tant qu'antagonistes du recepteur muscarinique - Google Patents

Aminoalkyl 1-lactames substituees et leur utilisation en tant qu'antagonistes du recepteur muscarinique

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Publication number
MA26906A1
MA26906A1 MA26922A MA26922A MA26906A1 MA 26906 A1 MA26906 A1 MA 26906A1 MA 26922 A MA26922 A MA 26922A MA 26922 A MA26922 A MA 26922A MA 26906 A1 MA26906 A1 MA 26906A1
Authority
MA
Morocco
Prior art keywords
receptor antagonists
aminoalkyl
muscarinic receptor
sup
compounds
Prior art date
Application number
MA26922A
Other languages
English (en)
Inventor
Charles Alois Dvorak
Lawrence Emerson Fisher
Keena Lynn Green
Ralph New Harris Iii
Hans Maag
Antony Prince
David Bruce Repke
Russell Stephen Stabler
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MA26906A1 publication Critical patent/MA26906A1/fr

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    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
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    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
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    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

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MA26922A 2000-05-25 2002-11-22 Aminoalkyl 1-lactames substituees et leur utilisation en tant qu'antagonistes du recepteur muscarinique MA26906A1 (fr)

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PL370799A1 (en) 2001-12-03 2005-05-30 F.Hoffmann-La Roche Ag Aminotetralin derivatives as muscarinic receptor antagonists
PL370765A1 (en) 2001-12-03 2005-05-30 F.Hoffmann-La Roche Ag 4-piperidinyl alkylamine derivatives as muscarinic receptor antagonists
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EP1811986B1 (fr) 2004-11-04 2014-03-26 XenoPort, Inc. Formes posologiques orales a liberation prolongee d'un promedicament de la gabapentine
EP1906952A4 (fr) 2005-07-01 2010-04-14 Jenrin Discovery Inhibiteurs mao-b utiles dans le traitement de l obésité
WO2007045979A1 (fr) 2005-10-19 2007-04-26 Ranbaxy Laboratories Limited Compositions pharmaceutiques d'antagonistes du recepteur muscarinique
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MY140835A (en) 2010-01-29
US7361648B2 (en) 2008-04-22
US20060287293A1 (en) 2006-12-21
RU2241702C2 (ru) 2004-12-10
BR0111061A (pt) 2003-04-15
EP1289965B1 (fr) 2005-10-26
PL361282A1 (en) 2004-10-04
HRP20020904A2 (en) 2004-12-31
US6667301B2 (en) 2003-12-23
NO20025640D0 (no) 2002-11-22
ATE307806T1 (de) 2005-11-15
IL152701A0 (en) 2003-06-24
AR028624A1 (es) 2003-05-14
CA2409841C (fr) 2009-04-14
PL204753B1 (pl) 2010-02-26
NZ522411A (en) 2004-05-28
TWI306095B (en) 2009-02-11
DE60114413D1 (de) 2005-12-01
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PE20011325A1 (es) 2002-01-03
EP1289965A1 (fr) 2003-03-12
ES2251517T3 (es) 2006-05-01
CN1178922C (zh) 2004-12-08
CZ20024200A3 (cs) 2004-01-14
CZ302807B6 (cs) 2011-11-23
UY26729A1 (es) 2001-12-28
CA2409841A1 (fr) 2001-11-29
US20040087581A1 (en) 2004-05-06
HUP0302010A2 (hu) 2003-09-29
JP4071000B2 (ja) 2008-04-02
AU782191B2 (en) 2005-07-07
AU1012202A (en) 2001-12-03
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US7094778B2 (en) 2006-08-22
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NO20025640L (no) 2003-01-22
YU88902A (sh) 2006-01-16

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