MA27084A1 - Compositions polymeres a liberation controlee, comprenant des composes favorisant la croissance osseuse. - Google Patents

Compositions polymeres a liberation controlee, comprenant des composes favorisant la croissance osseuse.

Info

Publication number
MA27084A1
MA27084A1 MA27688A MA27688A MA27084A1 MA 27084 A1 MA27084 A1 MA 27084A1 MA 27688 A MA27688 A MA 27688A MA 27688 A MA27688 A MA 27688A MA 27084 A1 MA27084 A1 MA 27084A1
Authority
MA
Morocco
Prior art keywords
bone growth
controlled release
fluid composition
polymer compositions
compound
Prior art date
Application number
MA27688A
Other languages
English (en)
Inventor
Francis Dumont
Mei Li
Richard Lee Dunn
Mingxing Zhou
Richard Wilker Korsmeyer
Vishwas Madhav Paralkar
Scott Alexander Jeffers
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of MA27084A1 publication Critical patent/MA27084A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

Abstract

DEPOSANT Société dite: PFIZER INC. REVENDICATION DE PRIORITES US 30 Novembre 2001 60/337,255 Voir en annexe le titre de l'invention et le texte de l'abrégé Compositions polymères à libération contrôlée, comprenant des composés favorisant la croissance osseuse La présente invention concerne un système perfectionné pour la libération contrôlée d'un composé favorisant la croissance osseuse, et une composition fluide pour sa formation. La composition fluide est constituée d'un composé favorisant la croissance osseuse, d'un polymère thermoplastique et d'un solvant organique. La composition fluide est capable de former une matrice polymère solide microporeuse biodégradable et/ou bioérodable. La matrice est utile comme implant chez des patients (homme et animaux) pour délivrer un composé favorisant la croissance osseuse à certains tissus.
MA27688A 2001-11-30 2004-05-20 Compositions polymeres a liberation controlee, comprenant des composes favorisant la croissance osseuse. MA27084A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33725501P 2001-11-30 2001-11-30

Publications (1)

Publication Number Publication Date
MA27084A1 true MA27084A1 (fr) 2004-12-20

Family

ID=23319774

Family Applications (1)

Application Number Title Priority Date Filing Date
MA27688A MA27084A1 (fr) 2001-11-30 2004-05-20 Compositions polymeres a liberation controlee, comprenant des composes favorisant la croissance osseuse.

Country Status (35)

Country Link
US (2) US20030104031A1 (fr)
EP (1) EP1448166A1 (fr)
JP (1) JP4903985B2 (fr)
KR (1) KR100629380B1 (fr)
CN (1) CN1599598A (fr)
AP (1) AP1781A (fr)
AR (1) AR037462A1 (fr)
AU (2) AU2002347502A1 (fr)
BR (1) BR0214610A (fr)
CA (1) CA2468703C (fr)
DO (1) DOP2002000534A (fr)
EA (1) EA011350B1 (fr)
EC (1) ECSP045124A (fr)
GE (1) GEP20063951B (fr)
GT (1) GT200200242A (fr)
HR (1) HRP20040486A2 (fr)
HU (1) HUP0402135A3 (fr)
IL (1) IL161835A0 (fr)
IS (1) IS7217A (fr)
MA (1) MA27084A1 (fr)
MX (1) MXPA04003723A (fr)
NO (1) NO20042273L (fr)
NZ (1) NZ533115A (fr)
OA (1) OA12731A (fr)
PA (1) PA8559001A1 (fr)
PE (1) PE20030581A1 (fr)
PL (1) PL370085A1 (fr)
PY (1) PY0229226A (fr)
SV (1) SV2004001421A (fr)
TN (1) TNSN04096A1 (fr)
TW (1) TW200300695A (fr)
UA (1) UA76792C2 (fr)
WO (1) WO2003045351A1 (fr)
YU (1) YU35004A (fr)
ZA (1) ZA200402755B (fr)

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US7074425B2 (en) * 2002-09-26 2006-07-11 Bonewax, Llc Hemostatic compositions and methods
EP1596765A2 (fr) * 2003-02-10 2005-11-23 Smith & Nephew, Inc. Dispositifs resorbables
GB0307011D0 (en) 2003-03-27 2003-04-30 Regentec Ltd Porous matrix
CN1909911A (zh) * 2003-10-01 2007-02-07 浩鼎生技公司 通过给予氨基糖治疗哺乳动物的疾病状态及其用途
GB0329654D0 (en) 2003-12-23 2004-01-28 Smith & Nephew Tunable segmented polyacetal
US8641738B1 (en) 2004-10-28 2014-02-04 James W. Ogilvie Method of treating scoliosis using a biological implant
US8123787B2 (en) 2004-10-28 2012-02-28 Ogilvie James W Method of treating scoliosis using a biological implant
JP2009504929A (ja) * 2005-08-18 2009-02-05 スミス アンド ネフュー ピーエルシー 高強度デバイス及び複合材料
CN100443065C (zh) * 2006-01-26 2008-12-17 上海交通大学 用于颌面骨缺损修复的复合体系植入体单元
ATE493081T1 (de) 2006-11-30 2011-01-15 Smith & Nephew Inc Faserverstärktes verbundmaterial
EP2142353A1 (fr) 2007-04-18 2010-01-13 Smith & Nephew PLC Moulage par expansion de polymères à mémoire de forme
EP2150288B1 (fr) 2007-04-19 2011-04-13 Smith & Nephew, Inc. Fixation de greffe
ATE547129T1 (de) 2007-04-19 2012-03-15 Smith & Nephew Inc Multimodale formgedächtnis-polymere
US8062739B2 (en) * 2007-08-31 2011-11-22 Zimmer, Inc. Hydrogels with gradient
US20090181068A1 (en) * 2008-01-14 2009-07-16 Dunn Richard L Low Viscosity Liquid Polymeric Delivery System
KR101626632B1 (ko) 2008-08-12 2016-06-01 노파르티스 아게 제약 조성물
EP2172189A1 (fr) * 2008-10-01 2010-04-07 Novartis AG Compositions pharmaceutiques
WO2010045487A1 (fr) * 2008-10-15 2010-04-22 Palmetto Biomedical, Inc. Dispositif et procédé destinés à fournir des agents thérapeutiques par le biais d'implants internes
US9642658B2 (en) 2008-10-15 2017-05-09 Orthoclip Llc Device and method for delivery of therapeutic agents via internal implants
WO2011015958A2 (fr) 2009-08-06 2011-02-10 Koninklijke Philips Electronics N.V. Oncothérapies utilisant des grains radioactifs
WO2013043569A1 (fr) 2011-09-20 2013-03-28 Vical Incorporated Immunothérapie combinée à action antitumorale synergique faisant appel à des alloantigènes
CN104189954B (zh) * 2014-09-19 2017-03-29 中国科学院长春应用化学研究所 一种原位固化组织工程支架及其制备方法
RU2571548C1 (ru) * 2014-12-17 2015-12-20 Федеральное государственное бюджетное учреждение науки Институт органической и физической химии им. А.Е. Арбузова Казанского научного центра Российской академии наук Ветеринарное имплантируемое средство пролонгированного действия (варианты)
CA3005313C (fr) 2015-11-16 2024-01-09 Evonik Rohm Gmbh Solution injectable comprenant un inhibiteur de transcriptase inverse non nucleosidique et du poly(lactide-co-glycolide)
CN109498852B (zh) * 2018-12-29 2022-06-24 广州噢斯荣医药技术有限公司 治疗骨科疾病的生物降解材料及其应用
WO2021090146A1 (fr) 2019-11-04 2021-05-14 Astrazeneca Ab Polythérapie pour le traitement du cancer
KR20230150790A (ko) 2020-12-29 2023-10-31 시노 메디칼 사이언시즈 테크놀로지, 인코포레이티드 약물 용출 스텐트
WO2024089417A1 (fr) 2022-10-24 2024-05-02 Memorial Sloan-Kettering Cancer Center Stratification de tumeurs pour déterminer la sensibilité à un inhibiteur de point de contrôle immunitaire
JP2025535474A (ja) 2022-10-24 2025-10-24 キャンサー・リサーチ・テクノロジー・リミテッド 酸化還元状態改変剤によるチェックポイント阻害剤に対する腫瘍の感応化
WO2024150017A1 (fr) 2023-01-13 2024-07-18 Akrivia Biomedics Limited Procédé de profilage de maladies
NL2037811B1 (en) 2024-05-29 2025-12-12 Univ Oslo Treatment for Cancer
GB202408360D0 (en) 2024-06-11 2024-07-24 Cancer Research Tech Ltd Tumour sensitisation
GB202417285D0 (en) 2024-11-25 2025-01-08 Univ Oxford Innovation Ltd Expanded t cell population
GB202418460D0 (en) 2024-12-16 2025-01-29 Univ Oxford Innovation Ltd Multivalent binding proteins

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ATE241394T1 (de) * 1994-04-08 2003-06-15 Atrix Lab Inc Beigeordnetes polymersystem zur verwendung mit einer medizinischen vorrichtung
AU4652596A (en) 1995-01-09 1996-07-31 Atrix Laboratories, Inc. Liquid polymer delivery system
UA59384C2 (uk) * 1996-12-20 2003-09-15 Пфайзер, Інк. Похідні сульфонамідів та амідів як агоністи простагландину, фармацевтична композиція та способи лікування на їх основі
ATE318580T1 (de) * 1996-12-20 2006-03-15 Alza Corp Gelzusammensetzungen und verfahren
UA67754C2 (uk) * 1997-10-10 2004-07-15 Пфайзер, Інк. Агоністи простагландину, фармацевтична композиція на їх основі (варіанти), спосіб нарощення та збереження кісткової маси у хребетних та спосіб лікування (варіанти)
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Also Published As

Publication number Publication date
PL370085A1 (en) 2005-05-16
EP1448166A1 (fr) 2004-08-25
MXPA04003723A (es) 2005-04-08
HRP20040486A2 (en) 2004-10-31
NZ533115A (en) 2005-12-23
EA200400608A1 (ru) 2004-10-28
AP2004003037A0 (en) 2004-06-30
PA8559001A1 (es) 2003-11-12
AR037462A1 (es) 2004-11-10
HUP0402135A3 (en) 2008-04-28
BR0214610A (pt) 2004-09-14
WO2003045351A1 (fr) 2003-06-05
US8017144B2 (en) 2011-09-13
UA76792C2 (uk) 2006-09-15
AU2002347502A1 (en) 2003-06-10
GEP20063951B (en) 2006-10-25
US20030104031A1 (en) 2003-06-05
PE20030581A1 (es) 2003-07-08
KR100629380B1 (ko) 2006-09-29
JP4903985B2 (ja) 2012-03-28
CA2468703C (fr) 2009-12-29
ZA200402755B (en) 2005-04-08
IS7217A (is) 2004-04-07
TW200300695A (en) 2003-06-16
US20090169595A1 (en) 2009-07-02
NO20042273L (no) 2004-07-14
KR20040062977A (ko) 2004-07-09
AP1781A (en) 2007-09-27
AU2009200125B2 (en) 2012-02-02
CA2468703A1 (fr) 2003-06-05
GT200200242A (es) 2003-06-25
YU35004A (sh) 2006-08-17
JP2005515190A (ja) 2005-05-26
ECSP045124A (es) 2004-07-23
EA011350B1 (ru) 2009-02-27
OA12731A (en) 2006-06-28
DOP2002000534A (es) 2003-05-31
AU2009200125A1 (en) 2009-02-05
TNSN04096A1 (fr) 2006-06-01
HUP0402135A2 (hu) 2005-02-28
PY0229226A (es) 2004-06-01
IL161835A0 (en) 2005-11-20
CN1599598A (zh) 2005-03-23
SV2004001421A (es) 2004-05-07

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