MA27860A1 - Derives de lincomycine nouveaux possedant une activite antimicrobienne - Google Patents

Derives de lincomycine nouveaux possedant une activite antimicrobienne

Info

Publication number: MA27860A1
Authority: MA; Morocco
Prior art keywords: new; lincomycin derivatives; antimicrobial activity; lincomycin; compounds
Prior art date: 2003-06-17

Application number

MA28672A

Other languages

English (en)

French (fr)

Inventor

Jason G Lewis

Sampath K Anandan

Hardwin O'dowd

Mikhail F Gordeev

Original Assignee

Vicuron Pharm Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-06-17

Filing date

2005-12-16

Publication date

2006-04-03

2003-08-15 Priority claimed from US10/642,807 external-priority patent/US7164011B2/en

2004-02-11 Priority claimed from US10/777,455 external-priority patent/US7199105B2/en

2005-12-16 Application filed by Vicuron Pharm Inc filed Critical Vicuron Pharm Inc

2006-04-03 Publication of MA27860A1 publication Critical patent/MA27860A1/fr

Links

OJMMVQQUTAEWLP-KIDUDLJLSA-N lincomycin Chemical class CN1C[C@H](CCC)C[C@H]1C(=O)N[C@H]([C@@H](C)O)[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@@H](SC)O1 OJMMVQQUTAEWLP-KIDUDLJLSA-N 0.000 title abstract 4
230000000845 anti-microbial effect Effects 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
241000894006 Bacteria Species 0.000 abstract 1
230000000844 anti-bacterial effect Effects 0.000 abstract 1
239000004599 antimicrobial Substances 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
230000003389 potentiating effect Effects 0.000 abstract 1
238000010189 synthetic method Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
- C07H15/16—Lincomycin; Derivatives thereof

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
Epidemiology (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Crystallography & Structural Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Saccharide Compounds (AREA)

MA28672A 2003-06-17 2005-12-16 Derives de lincomycine nouveaux possedant une activite antimicrobienne MA27860A1 (fr)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US47929603P	2003-06-17	2003-06-17
US47950203P	2003-06-17	2003-06-17
US10/642,807 US7164011B2 (en)	2002-08-15	2003-08-15	Lincomycin derivatives possessing antibacterial activity
US10/777,455 US7199105B2 (en)	2002-08-15	2004-02-11	Lincomycin derivatives possessing antibacterial activity

Publications (1)

Publication Number	Publication Date
MA27860A1 true MA27860A1 (fr)	2006-04-03

Family

ID=40203032

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA28672A MA27860A1 (fr)	2003-06-17	2005-12-16	Derives de lincomycine nouveaux possedant une activite antimicrobienne

Country Status (16)

Country	Link
EP (1)	EP1644393A2 (sr)
JP (1)	JP2007516172A (sr)
KR (1)	KR20060091050A (sr)
AU (1)	AU2004261550A1 (sr)
BR (1)	BRPI0411534A (sr)
CA (1)	CA2528592A1 (sr)
EC (1)	ECSP056233A (sr)
GE (1)	GEP20084437B (sr)
IL (1)	IL172183A0 (sr)
IS (1)	IS8147A (sr)
MA (1)	MA27860A1 (sr)
MX (1)	MXPA05013915A (sr)
NO (1)	NO20055893L (sr)
OA (1)	OA13179A (sr)
RS (1)	RS20050931A (sr)
WO (1)	WO2005012320A2 (sr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7164011B2 (en)	2002-08-15	2007-01-16	Vicuron Pharmaceuticals, Inc.	Lincomycin derivatives possessing antibacterial activity
US7199105B2 (en)	2002-08-15	2007-04-03	Vicuron Pharmaceuticals, Inc.	Lincomycin derivatives possessing antibacterial activity
US7256177B2 (en)	2003-06-17	2007-08-14	Vicuron Pharmaceuticals, Inc.	Lincomycin derivatives possessing antibacterial activity
WO2005007665A2 (en) *	2003-06-17	2005-01-27	Vicuron Pharmaceuticals Inc.	Lincomycin derivatives possessing antibacterial activity
US7199106B2 (en)	2003-06-17	2007-04-03	Vicuron Pharmaceuticals, Inc.	Lincomycin derivatives possessing antimicrobial activity
US7361743B2 (en)	2004-02-11	2008-04-22	Pfizer Inc	Lincomycin derivatives possessing antibacterial activity
JP2009507793A (ja) *	2005-08-31	2009-02-26	ワイス	グリシルサイクリンの９−アミノカルボニル置換誘導体
EP1970377A4 (en)	2005-12-09	2013-02-27	Meiji Seika Kaisha	LINCOMYCIN DERIVATIVE AND ANTIBACTERIAL AGENT CONTAINING THIS AS AN ACTIVE SUBSTANCE
US7867980B2 (en)	2007-05-31	2011-01-11	Meiji Seika Kaisha, Ltd.	Lincosamide derivatives and antimicrobial agents comprising the same as active ingredient
US7879808B2 (en)	2007-05-31	2011-02-01	Meiji Seika Kaisha, Ltd.	Lincomycin derivatives and antimicrobial agents comprising the same as active ingredient
US8822679B2 (en) *	2011-06-24	2014-09-02	California Institute Of Technology	Quaternary heteroatom containing compounds
US20130267699A1 (en)	2011-06-24	2013-10-10	California Institute Of Technology	Quaternary heteroatom containing compounds
US10421696B2 (en)	2014-12-18	2019-09-24	California Institute Of Technology	Enantioselective synthesis of α-quaternary mannich adducts by palladium-catalyzed allylic alkylation
CN107922373A (zh)	2015-03-27	2018-04-17	加利福尼亚技术学院	使用低催化剂浓度和稳定的预催化剂的不对称催化脱羧烷基烷基化
WO2017156239A1 (en)	2016-03-11	2017-09-14	California Institute Of Technology	Compositions and methods for acylating lactams
EP3480190B1 (en)	2017-11-01	2023-01-04	California Institute of Technology	Methods for enantioselective allylic alkylation of esters, lactones, and lactams with unactivated allylic alcohols
US11214568B2 (en)	2018-10-18	2022-01-04	California Institute Of Technology	Gem-disubstituted pyrrolidines, piperazines, and diazepanes, and compositions and methods of making the same
CN110357839A (zh) *	2019-08-29	2019-10-22	重庆经致制药技术开发有限公司	布瓦西坦手性中间体的制备方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL128232C (sr) *	1964-04-13
US3268556A (en) *	1964-04-13	1966-08-23	Upjohn Co	Novel lincomycin derivatives
NL146501C (sr) *	1964-07-01
US3282917A (en) *	1964-08-17	1966-11-01	Upjohn Co	Methyl n-(1-alkyl-4-alkoxy-prolyl)-alpha-thiolincosaminide compounds and process therefor
NL140527B (nl) *	1965-02-08	1973-12-17	Upjohn Co	Werkwijze ter bereiding van aan lincomycine verwante verbindingen.
US3496163A (en) *	1965-02-08	1970-02-17	Upjohn Co	7-halo-7-deoxylincomycins and process for preparing the same
US3555007A (en) *	1968-07-22	1971-01-12	Upjohn Co	7-deoxy-7-halo lincomycin d derivatives
US3549615A (en) *	1968-10-17	1970-12-22	Upjohn Co	Lincomycin derivatives and process for producing the same
DE2118636A1 (de) *	1970-04-20	1971-11-04	The Upjohn Co., Kalamazoo, Mich. (V.StA.)	3-Nucleotide von Lincomycin und deren Analogen, Verfahren zu ihrer Herstellung und ihre Verwendung in therapeutischen Präparaten
US3787390A (en) *	1971-06-23	1974-01-22	Upjohn Co	Analogs of lincomycin and process
US3849396A (en) *	1973-01-08	1974-11-19	Upjohn Co	Lincomycin and clindamycin 1-o-ethers
US3923602A (en) *	1973-10-25	1975-12-02	Upjohn Co	Composition of matter and process
JPS5641239A (en) *	1979-09-13	1981-04-17	Hitachi Cable Ltd	Flame-retardant composition
US4278789A (en) *	1979-11-23	1981-07-14	The Upjohn Company	Lincomycin compounds
US7164011B2 (en) *	2002-08-15	2007-01-16	Vicuron Pharmaceuticals, Inc.	Lincomycin derivatives possessing antibacterial activity
JP2007528360A (ja) *	2003-06-17	2007-10-11	ビキュロン・ファーマシューティカルズ・インコーポレイテッド	抗菌活性を有するリンコマイシン誘導体

2004
- 2004-06-17 AU AU2004261550A patent/AU2004261550A1/en not_active Abandoned
- 2004-06-17 WO PCT/US2004/019689 patent/WO2005012320A2/en not_active Ceased
- 2004-06-17 GE GEAP20049117A patent/GEP20084437B/en unknown
- 2004-06-17 KR KR1020057024291A patent/KR20060091050A/ko not_active Ceased
- 2004-06-17 EP EP04776816A patent/EP1644393A2/en not_active Withdrawn
- 2004-06-17 JP JP2006517464A patent/JP2007516172A/ja active Pending
- 2004-06-17 CA CA002528592A patent/CA2528592A1/en not_active Abandoned
- 2004-06-17 MX MXPA05013915A patent/MXPA05013915A/es unknown
- 2004-06-17 RS YUP-2005/0931A patent/RS20050931A/sr unknown
- 2004-06-17 OA OA1200500364A patent/OA13179A/en unknown
- 2004-06-17 BR BRPI0411534-1A patent/BRPI0411534A/pt not_active IP Right Cessation
2005
- 2005-11-24 IL IL172183A patent/IL172183A0/en unknown
- 2005-11-24 IS IS8147A patent/IS8147A/is unknown
- 2005-12-12 NO NO20055893A patent/NO20055893L/no not_active Application Discontinuation
- 2005-12-16 EC EC2005006233A patent/ECSP056233A/es unknown
- 2005-12-16 MA MA28672A patent/MA27860A1/fr unknown

Also Published As

Publication number	Publication date
WO2005012320A3 (en)	2005-10-20
EP1644393A2 (en)	2006-04-12
OA13179A (en)	2006-12-13
IS8147A (is)	2005-11-24
WO2005012320A2 (en)	2005-02-10
BRPI0411534A (pt)	2006-08-22
IL172183A0 (en)	2011-08-01
JP2007516172A (ja)	2007-06-21
CA2528592A1 (en)	2005-02-10
AU2004261550A1 (en)	2005-02-10
HK1090061A1 (zh)	2006-12-15
GEP20084437B (en)	2008-07-25
ECSP056233A (es)	2006-04-19
MXPA05013915A (es)	2006-07-03
KR20060091050A (ko)	2006-08-17
NO20055893L (no)	2006-03-14
RS20050931A (sr)	2008-04-04

Publication	Publication Date	Title
MA27860A1 (fr)	2006-04-03	Derives de lincomycine nouveaux possedant une activite antimicrobienne
WO2000034265A3 (en)	2002-10-03	Quinoline-indole antimicrobial agents
MA27180A1 (fr)	2005-01-03	N-aryl-2-oxazolidinone-5-carboxamides et leurs derives, et leur utilisation comme agents antibacteriens
WO2001040223A3 (en)	2001-12-20	Aminoheterocyclylamides as pesticides and antiparasitic agents
WO2001046165A3 (en)	2001-12-06	N-heteroaryl-amides and their use as parasiticides
NO996269L (no)	2000-02-16	Kinolin-indol antimikrobielle midler, samt anvendelse og blandinger derav
ID18883A (id)	1998-05-20	Pesaing 5-ht 1f
DE69227595D1 (de)	1998-12-17	Zusammensetzungen und verfahren zur bekämpfung mikrobiellen wachstums in wässrige medien
DK0897904T3 (da)	2002-04-02	Fungicide 2-methoxybenzophenoner
TW200734303A (en)	2007-09-16	Organic compounds
WO2006055070A3 (en)	2006-07-20	Novel lincomycin derivatives possessing antibacterial activity
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ATE299505T1 (de)	2005-07-15	Fungizide 6-(2-halo-4-alkoxyphenyl)- triazolopyrimidine
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TW200602295A (en)	2006-01-16	Organic compounds
WO2004016632A8 (en)	2004-09-30	Lincomycin derivatives possessing antibacterial activity
TR199901017A2 (xx)	1999-12-21	B�cek ilac� terkibi.
TR200301650T4 (tr)	2004-03-22	Ziraat ve bahçecilikte kullanım için okzim O-eter bileşikleri ve fungusitler
AU6332799A (en)	2000-05-01	Hydroxystilbene compounds used as microbicidal active substances
WO2004043928A3 (en)	2004-07-01	N-sulfonyl-4-methyleneamino-3-hydroxy-2-pyridones as antimicrobial agents
TW200613251A (en)	2006-05-01	Organic compounds
WO2004034961A3 (en)	2004-12-02	Antimicrobial agents and uses thereof
WO2006097758A3 (en)	2007-03-01	Antimicrobial composition
MXPA04007048A (es)	2004-10-11	Derivados de amidoacetonitrilo.
DE60009319D1 (de)	2004-04-29	Substituierte n-phenyl-2-hydroxy-2-methyl-3,3,3-trifluorpropanamid-derivative zur erhöhung der pyruvatdehydrogenaseaktivität