MA28032A1 - Utilisation de cyclosporines modifiees pour le traitement de troubles lies au vhc - Google Patents
Utilisation de cyclosporines modifiees pour le traitement de troubles lies au vhcInfo
- Publication number
- MA28032A1 MA28032A1 MA28865A MA28865A MA28032A1 MA 28032 A1 MA28032 A1 MA 28032A1 MA 28865 A MA28865 A MA 28865A MA 28865 A MA28865 A MA 28865A MA 28032 A1 MA28032 A1 MA 28032A1
- Authority
- MA
- Morocco
- Prior art keywords
- treatment
- related disorders
- cyclosporins
- hcv related
- modified cyclosporins
- Prior art date
Links
- 108010036941 Cyclosporins Proteins 0.000 title abstract 2
- 229930182912 cyclosporin Natural products 0.000 title abstract 2
- 102000001493 Cyclophilins Human genes 0.000 abstract 1
- 108010068682 Cyclophilins Proteins 0.000 abstract 1
- 208000010710 hepatitis C virus infection Diseases 0.000 abstract 1
- 230000001506 immunosuppresive effect Effects 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Cette invention concerne ses cyclosporines sans activité immunosuppressive se liant à la cyclophiline (voir formules I, Ia ou II) comme définies dans le descriptif, qui possèdent des propriétés puissantes dans la prévention ou le traitement des infections par le virus de l'hépatite C.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0320638.0A GB0320638D0 (en) | 2003-09-03 | 2003-09-03 | Organic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA28032A1 true MA28032A1 (fr) | 2006-07-03 |
Family
ID=28686843
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA28865A MA28032A1 (fr) | 2003-09-03 | 2006-03-10 | Utilisation de cyclosporines modifiees pour le traitement de troubles lies au vhc |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US7968518B2 (fr) |
| EP (2) | EP1797892B1 (fr) |
| JP (1) | JP4688806B2 (fr) |
| KR (1) | KR101116968B1 (fr) |
| CN (1) | CN1842343A (fr) |
| AU (2) | AU2004268382A1 (fr) |
| BR (1) | BRPI0414062B8 (fr) |
| CA (1) | CA2537137C (fr) |
| CY (1) | CY1110506T1 (fr) |
| DE (1) | DE602004022061D1 (fr) |
| DK (1) | DK1663287T3 (fr) |
| ES (1) | ES2328361T3 (fr) |
| GB (1) | GB0320638D0 (fr) |
| HR (1) | HRP20090535T1 (fr) |
| IL (1) | IL173909A (fr) |
| IS (1) | IS2917B (fr) |
| MA (1) | MA28032A1 (fr) |
| MX (1) | MXPA06002394A (fr) |
| NO (1) | NO20061479L (fr) |
| NZ (1) | NZ545495A (fr) |
| PL (1) | PL1663287T3 (fr) |
| PT (1) | PT1663287E (fr) |
| RU (1) | RU2389501C2 (fr) |
| SG (1) | SG149063A1 (fr) |
| SI (1) | SI1663287T1 (fr) |
| TN (1) | TNSN06071A1 (fr) |
| TW (1) | TWI342782B (fr) |
| WO (1) | WO2005021028A1 (fr) |
| ZA (1) | ZA200601550B (fr) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU759480B2 (en) | 1998-07-01 | 2003-04-17 | Debiopharm S.A. | Novel cyclosporin with improved activity profile |
| US7538084B2 (en) | 2003-03-17 | 2009-05-26 | Amr Technology, Inc. | Cyclosporins |
| GB0320638D0 (en) | 2003-09-03 | 2003-10-01 | Novartis Ag | Organic compounds |
| GB0500020D0 (en) * | 2005-01-04 | 2005-02-09 | Novartis Ag | Organic compounds |
| US7671017B2 (en) | 2004-07-14 | 2010-03-02 | Novartis Ag | Use of a combination of cyclosporine and pegylated interferon for treating hepatitis C (HCV) |
| JP2008514701A (ja) | 2004-09-29 | 2008-05-08 | エーエムアール テクノロジー インコーポレイテッド | シクロスポリンアルキン類似体およびそれらの薬学的使用 |
| JP2008514702A (ja) | 2004-09-29 | 2008-05-08 | エーエムアール テクノロジー インコーポレイテッド | 新規シクロスポリン類似体およびそれらの薬学的使用 |
| US7196161B2 (en) | 2004-10-01 | 2007-03-27 | Scynexis Inc. | 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection |
| SI1802650T1 (sl) * | 2004-10-01 | 2012-03-30 | Scynexis Inc | Eter in tioeter substituirani ciklosporinski derivati za zdravljenje in preventivo pred infekcijami s hepatitisom c |
| DK1793844T3 (da) * | 2004-10-01 | 2011-03-21 | Debiopharm Sa | Anvendelse af [D-MeAla]3-[EtVal]4-cyklosporin til behandling af hepatitis C-infektion |
| JP2008515886A (ja) | 2004-10-06 | 2008-05-15 | エーエムアール テクノロジー インコーポレイテッド | シクロスポリンアルキンおよびそれらの医用薬剤としての有用性 |
| ES2314731T3 (es) | 2004-11-22 | 2009-03-16 | Astellas Pharma Inc. | Analogo de ciclosporina. |
| AU2005322241B2 (en) * | 2004-12-23 | 2010-02-18 | Novartis Ag | Compounds for flaviviridae treatment |
| WO2006071619A1 (fr) | 2004-12-23 | 2006-07-06 | Novartis Ag | Compositions pour le traitement du vhc |
| AU2006259348B2 (en) | 2005-06-17 | 2010-07-22 | Novartis Ag | Use of sanglifehrin in HCV |
| CN101316606B (zh) * | 2005-09-30 | 2015-05-27 | 西尼克斯公司 | 治疗和预防丙型肝炎感染的方法和药物组合物 |
| JP5517454B2 (ja) * | 2005-09-30 | 2014-06-11 | スシネキス インク | C型肝炎感染の治療及び予防のための方法及び医薬組成物 |
| EP1931696B1 (fr) | 2005-09-30 | 2011-02-16 | Scynexis, Inc. | Derives d'arylalkyle et d'heteroarylalkyle de cyclosporine a utilises pour traiter et prevenir une infection virale |
| PT1957518E (pt) * | 2005-10-26 | 2016-02-26 | Astellas Pharma Inc | Novos compostos peptídicos cíclicos |
| US7696166B2 (en) | 2006-03-28 | 2010-04-13 | Albany Molecular Research, Inc. | Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders |
| US7696165B2 (en) | 2006-03-28 | 2010-04-13 | Albany Molecular Research, Inc. | Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders |
| EP2023918B1 (fr) | 2006-05-19 | 2011-03-23 | Scynexis, Inc. | Cyclosporines pour le traitement et la prévention de troubles oculaires |
| CN101502196A (zh) * | 2006-06-02 | 2009-08-05 | 克洛德·安妮·佩里西恩 | 激活电子的管理 |
| CA2665415A1 (fr) * | 2006-10-12 | 2008-04-17 | Novartis Ag | Utilisation de cyclosporines modifiees |
| WO2008069917A2 (fr) * | 2006-11-20 | 2008-06-12 | Scynexis, Inc. | Nouveaux peptides cycliques |
| US8450281B2 (en) | 2007-01-04 | 2013-05-28 | Debiopharm S.A. | Non-immunosuppressive cyclosporin for treatment of Ullrich congenital muscular dystrophy |
| KR20100017547A (ko) * | 2007-05-02 | 2010-02-16 | 아스텔라스세이야쿠 가부시키가이샤 | 신규 시클릭 펩티드 화합물 |
| WO2009028418A1 (fr) | 2007-08-24 | 2009-03-05 | Sapporo Medical University | Protéine de liaison à la cyclosporine a |
| US20090306033A1 (en) * | 2008-06-06 | 2009-12-10 | Keqiang Li | Novel cyclic peptides |
| CN102083852A (zh) * | 2008-06-06 | 2011-06-01 | 西尼克斯公司 | 环孢菌素类似物及其在治疗hcv感染中的应用 |
| AU2009276241A1 (en) * | 2008-07-30 | 2010-02-04 | Ciclofilin Pharmaceuticals Corp. | Nonimmunosuppressive cyclosporine analogue molecules |
| CN102164947A (zh) * | 2008-09-24 | 2011-08-24 | 安斯泰来制药有限公司 | 肽化合物及其制备方法 |
| CN102202679B (zh) | 2008-11-06 | 2014-05-07 | 帝柏奥研究制药有限公司 | 环十一缩酚酸肽化合物及其作为药物的用途 |
| EP2376524B1 (fr) * | 2008-12-31 | 2017-03-15 | Cypralis Limited | Dérivés de cyclosporine a |
| KR20110111321A (ko) * | 2009-01-30 | 2011-10-10 | 이난타 파마슈티칼스, 인코포레이티드 | C형 간염을 예방하거나 치료하기 위한 사이클로스포린 유사체 |
| US8481483B2 (en) | 2009-02-19 | 2013-07-09 | Enanta Pharmaceuticals, Inc. | Cyclosporin analogues |
| US8367053B2 (en) | 2009-07-09 | 2013-02-05 | Enanta Pharmaceuticals, Inc. | Cyclosporin analogues |
| US8685917B2 (en) | 2009-07-09 | 2014-04-01 | Enanta Pharmaceuticals, Inc. | Cyclosporin analogues |
| US8349312B2 (en) | 2009-07-09 | 2013-01-08 | Enanta Pharmaceuticals, Inc. | Proline substituted cyclosporin analogues |
| WO2011063076A1 (fr) | 2009-11-19 | 2011-05-26 | Itherx Pharmaceuticals, Inc. | Méthodes de traitement du virus de l'hépatite c avec des composés d'oxo-acétamide |
| US20110144005A1 (en) | 2009-12-09 | 2011-06-16 | Scynexis, Inc. | Novel cyclic peptides |
| US8623814B2 (en) | 2010-02-23 | 2014-01-07 | Enanta Pharmaceuticals, Inc. | Antiviral agents |
| CN103179974A (zh) | 2010-10-05 | 2013-06-26 | 诺华有限公司 | 丙型肝炎病毒感染的新疗法 |
| CA2818067A1 (fr) | 2010-11-30 | 2012-06-07 | Novartis Ag | Nouveaux traitements de l'infection par le virus de l'hepatite c |
| JO3337B1 (ar) | 2010-12-13 | 2019-03-13 | Debiopharm Sa | تركيبات صيدلية تشمل أليسبوريفير |
| BR112013014890B1 (pt) | 2010-12-15 | 2023-10-24 | Contravir Pharmaceuticals, Inc | Composto análogo de moléculas pertencentes à família ciclosporina, composição farmacêutica compreendendo o mesmo, uso terapêutico ou profilático do referido composto e processos para a preparação dos mesmos |
| AU2012233644A1 (en) | 2011-03-31 | 2013-09-12 | Novartis Ag | Alisporivir to treat Hepatitis C virus infection |
| AU2012237295A1 (en) | 2011-04-01 | 2013-09-19 | Novartis Ag | Treatment for infection with Hepatitis B virus alone or in combination with Hepatitis Delta virus and associated liver diseases |
| CN103648516A (zh) | 2011-04-13 | 2014-03-19 | 诺华股份有限公司 | 使用阿拉泊韦治疗丙型肝炎病毒感染 |
| RU2014116988A (ru) | 2011-09-27 | 2015-11-10 | Новартис Аг | Алиспоривир для лечения инфекции, вызванной вирусом гепатита с |
| JP2015516423A (ja) | 2012-05-07 | 2015-06-11 | ノバルティス アーゲー | アリスポリビルによる薬物動態の調節 |
| JP2015519368A (ja) | 2012-06-01 | 2015-07-09 | アラーガン インコーポレイテッドAllergan,Incorporated | シクロスポリンa類似体 |
| WO2014085623A1 (fr) | 2012-11-28 | 2014-06-05 | Enanta Pharmaceuticals, Inc. | Nouveaux analogues de [n-me-4-hydroxyleucine]-9-cyclosporine |
| WO2015008223A1 (fr) | 2013-07-17 | 2015-01-22 | Novartis Ag | Traitement du virus de l'hépatite c avec l'alisporivir et la ribavirine |
| JP2016538317A (ja) | 2013-08-26 | 2016-12-08 | エナンタ ファーマシューティカルズ インコーポレイテッド | C型肝炎を防止または治療するための新規シクロスポリン類似体 |
| WO2015136455A1 (fr) | 2014-03-13 | 2015-09-17 | Novartis Ag | Nouveaux traitements d'une infection par le virus de l'hépatite c |
| US9669095B2 (en) | 2014-11-03 | 2017-06-06 | Enanta Pharmaceuticals, Inc. | Cyclosporin analogues for preventing or treating hepatitis C infection |
| US9914755B2 (en) | 2015-01-08 | 2018-03-13 | Allergan, Inc. | Cyclosporin derivatives wherein the MeBmt sidechain has been cyclized |
| WO2022043678A1 (fr) * | 2020-08-24 | 2022-03-03 | Nanomerics Limited | Inhibiteurs viraux |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5639724A (en) * | 1984-07-24 | 1997-06-17 | Sandoz Ltd. | Cyclosporin galenic forms |
| US4917888A (en) | 1985-06-26 | 1990-04-17 | Cetus Corporation | Solubilization of immunotoxins for pharmaceutical compositions using polymer conjugation |
| US4766106A (en) | 1985-06-26 | 1988-08-23 | Cetus Corporation | Solubilization of proteins for pharmaceutical compositions using polymer conjugation |
| JP2514950B2 (ja) | 1986-03-10 | 1996-07-10 | エフ・ホフマン―ラ ロシユ アーゲー | 化学修飾蛋白質,その製造法および中間体 |
| KR0148748B1 (ko) | 1988-09-16 | 1998-08-17 | 장 크라메르, 한스 루돌프 하우스 | 사이클로스포린을 함유하는 약학조성물 |
| FI111730B (fi) * | 1990-11-02 | 2003-09-15 | Novartis Ag | Menetelmä ei-immunosuppressiivisen syklosporiinin valmistamiseksi |
| US5595732A (en) | 1991-03-25 | 1997-01-21 | Hoffmann-La Roche Inc. | Polyethylene-protein conjugates |
| US5382657A (en) | 1992-08-26 | 1995-01-17 | Hoffmann-La Roche Inc. | Peg-interferon conjugates |
| US6174868B1 (en) * | 1992-09-10 | 2001-01-16 | Isis Pharmaceuticals, Inc. | Compositions and methods for treatment of hepatitis C virus-associated diseases |
| DE69321823T2 (de) | 1992-10-21 | 1999-06-02 | Taito Co., Ltd., Tokio/Tokyo | 2-amino-1, 3- propandiolverbindung und immunosuppressium |
| ATE214940T1 (de) | 1993-11-10 | 2002-04-15 | Enzon Inc | Verbesserte interferon-polymerkonjugate |
| EP0778263B1 (fr) | 1994-08-22 | 2002-01-09 | Welfide Corporation | Compose benzenique et son utilisation medicale |
| US5824784A (en) | 1994-10-12 | 1998-10-20 | Amgen Inc. | N-terminally chemically modified protein compositions and methods |
| JP3786447B2 (ja) * | 1995-03-31 | 2006-06-14 | エーザイ株式会社 | C型肝炎の予防・治療剤 |
| US5908621A (en) * | 1995-11-02 | 1999-06-01 | Schering Corporation | Polyethylene glycol modified interferon therapy |
| FR2757521B1 (fr) | 1996-12-24 | 1999-01-29 | Rhone Poulenc Rorer Sa | Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2757520B1 (fr) | 1996-12-24 | 1999-01-29 | Rhone Poulenc Rorer Sa | Derive de cyclosporine, sa preparation et les compositions pharmaceutiques qui le contiennent |
| FR2757522B1 (fr) | 1996-12-24 | 1999-01-29 | Rhone Poulenc Rorer Sa | Derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent |
| ES2240868T3 (es) | 1997-04-04 | 2005-10-16 | Mitsubishi Pharma Corporation | Compuesto de 2-aminopropano -1,3-diol, su uso farmaceutico e intermedios en su sintesis. |
| JPH1180026A (ja) * | 1997-09-02 | 1999-03-23 | Yoshitomi Pharmaceut Ind Ltd | 新規免疫抑制剤、その使用方法およびその同定方法 |
| GB9811854D0 (en) * | 1998-06-02 | 1998-07-29 | Ciba Geigy Ag | Organic compounds |
| AU759480B2 (en) | 1998-07-01 | 2003-04-17 | Debiopharm S.A. | Novel cyclosporin with improved activity profile |
| CN1328387C (zh) | 2000-07-13 | 2007-07-25 | 三共株式会社 | 氨基醇衍生物 |
| EP1315735A4 (fr) | 2000-08-31 | 2005-04-06 | Merck & Co Inc | Derives de phosphates utilises en tant qu'agents immuno-regulateurs |
| AU2001295966A1 (en) * | 2000-10-19 | 2002-04-29 | Fujisawa Pharmaceutical Co. Ltd. | Cell damage inhibitor |
| JP2002125683A (ja) * | 2000-10-27 | 2002-05-08 | Tokyoto Igaku Kenkyu Kiko | インターフェロンの有効性を予測する方法並びにそれに用いられるプライマー及びプローブ |
| CA2442178A1 (fr) | 2001-03-26 | 2002-10-03 | Novartis Ag | Derives de 2-amino-propanol |
| JP2002316985A (ja) | 2001-04-20 | 2002-10-31 | Sankyo Co Ltd | ベンゾチオフェン誘導体 |
| CA2461212C (fr) | 2001-09-27 | 2010-08-17 | Kyorin Pharmaceutical Co., Ltd. | Derive de sulfure de diaryle, sels correspondant et agents immunosuppresseur utilisant ces derives |
| DE60235900D1 (de) | 2001-09-27 | 2010-05-20 | Kyorin Seiyaku Kk | Osuppressivum |
| ATE448193T1 (de) | 2002-01-18 | 2009-11-15 | Merck & Co Inc | ßN-(BENZYL)AMINOALKYL CARBOXYLATE, PHOSPHINATE, PHOSPHONATE UND TETRAZOLE ALS EDG REZEPTORAGONISTENß |
| JP4430941B2 (ja) | 2002-01-18 | 2010-03-10 | メルク エンド カムパニー インコーポレーテッド | Edg受容体作動薬 |
| US20030213603A1 (en) * | 2002-05-14 | 2003-11-20 | Fisher David B. | Dual use extension apparatus for a tool |
| CN1678326A (zh) | 2002-06-28 | 2005-10-05 | 埃迪尼克斯(开曼)有限公司 | 用于治疗黄病毒感染的2'-c-甲基-3'-o-l-缬氨酸酯核糖呋喃基胞苷 |
| GB0313444D0 (en) | 2003-06-11 | 2003-07-16 | Midland Medical Technologies L | Modular dysplasia cup |
| GB0320638D0 (en) | 2003-09-03 | 2003-10-01 | Novartis Ag | Organic compounds |
| DK1793844T3 (da) | 2004-10-01 | 2011-03-21 | Debiopharm Sa | Anvendelse af [D-MeAla]3-[EtVal]4-cyklosporin til behandling af hepatitis C-infektion |
| WO2006071619A1 (fr) | 2004-12-23 | 2006-07-06 | Novartis Ag | Compositions pour le traitement du vhc |
-
2003
- 2003-09-03 GB GBGB0320638.0A patent/GB0320638D0/en not_active Ceased
-
2004
- 2004-09-02 ES ES04764762T patent/ES2328361T3/es not_active Expired - Lifetime
- 2004-09-02 MX MXPA06002394A patent/MXPA06002394A/es active IP Right Grant
- 2004-09-02 EP EP06125649.1A patent/EP1797892B1/fr not_active Expired - Lifetime
- 2004-09-02 CN CNA2004800246044A patent/CN1842343A/zh active Pending
- 2004-09-02 CA CA2537137A patent/CA2537137C/fr not_active Expired - Fee Related
- 2004-09-02 PT PT04764762T patent/PT1663287E/pt unknown
- 2004-09-02 US US10/570,097 patent/US7968518B2/en active Active
- 2004-09-02 TW TW093126578A patent/TWI342782B/zh not_active IP Right Cessation
- 2004-09-02 KR KR1020067004342A patent/KR101116968B1/ko not_active Expired - Fee Related
- 2004-09-02 NZ NZ545495A patent/NZ545495A/en not_active IP Right Cessation
- 2004-09-02 JP JP2006525712A patent/JP4688806B2/ja not_active Expired - Fee Related
- 2004-09-02 DE DE602004022061T patent/DE602004022061D1/de not_active Expired - Lifetime
- 2004-09-02 PL PL04764762T patent/PL1663287T3/pl unknown
- 2004-09-02 HR HR20090535T patent/HRP20090535T1/hr unknown
- 2004-09-02 EP EP04764762A patent/EP1663287B1/fr not_active Expired - Lifetime
- 2004-09-02 RU RU2006110533/15A patent/RU2389501C2/ru not_active IP Right Cessation
- 2004-09-02 BR BRPI0414062A patent/BRPI0414062B8/pt not_active IP Right Cessation
- 2004-09-02 DK DK04764762T patent/DK1663287T3/da active
- 2004-09-02 AU AU2004268382A patent/AU2004268382A1/en not_active Abandoned
- 2004-09-02 SG SG200809555-6A patent/SG149063A1/en unknown
- 2004-09-02 WO PCT/EP2004/009804 patent/WO2005021028A1/fr not_active Ceased
- 2004-09-02 SI SI200431200T patent/SI1663287T1/sl unknown
-
2006
- 2006-02-22 ZA ZA200601550A patent/ZA200601550B/en unknown
- 2006-02-23 IL IL173909A patent/IL173909A/en active IP Right Grant
- 2006-03-02 TN TNP2006000071A patent/TNSN06071A1/en unknown
- 2006-03-10 MA MA28865A patent/MA28032A1/fr unknown
- 2006-03-24 IS IS8371A patent/IS2917B/is unknown
- 2006-03-31 NO NO20061479A patent/NO20061479L/no not_active Application Discontinuation
-
2008
- 2008-07-09 AU AU2008203031A patent/AU2008203031B2/en not_active Ceased
-
2009
- 2009-09-16 CY CY20091100955T patent/CY1110506T1/el unknown
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