MA28033A1 - Preparation pharmaceutique comprenant un derive de la pyrimidine-a-one enrobe d'un polymere enterique - Google Patents

Preparation pharmaceutique comprenant un derive de la pyrimidine-a-one enrobe d'un polymere enterique

Info

Publication number
MA28033A1
MA28033A1 MA28866A MA28866A MA28033A1 MA 28033 A1 MA28033 A1 MA 28033A1 MA 28866 A MA28866 A MA 28866A MA 28866 A MA28866 A MA 28866A MA 28033 A1 MA28033 A1 MA 28033A1
Authority
MA
Morocco
Prior art keywords
enteric polymer
pyrimidine
derived
pharmaceutical preparation
phospholipase
Prior art date
Application number
MA28866A
Other languages
English (en)
Inventor
Marinus Johannes Van Schie Dirk
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of MA28033A1 publication Critical patent/MA28033A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Formulation pharmaceutique comprenant un dérivé de pyrimidine-A-one enrobé avec un polymère entérique La présente invention propose des formulations de comprimés enrobés avec un polymère entérique pour administration orale, qui comprennent un inhibiteur de l'enzyme phospholipase A2 consistant en la phospholipase A2 associée aux lipoprotéines (Lp-PLA2), les procédés pour la préparation de telles formulations et leur utilisation en thérapeutique, en particulier dans le traitement de l'athérosclérose.
MA28866A 2003-09-02 2006-03-10 Preparation pharmaceutique comprenant un derive de la pyrimidine-a-one enrobe d'un polymere enterique MA28033A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0320522.6A GB0320522D0 (en) 2003-09-02 2003-09-02 Formulation

Publications (1)

Publication Number Publication Date
MA28033A1 true MA28033A1 (fr) 2006-07-03

Family

ID=28686767

Family Applications (1)

Application Number Title Priority Date Filing Date
MA28866A MA28033A1 (fr) 2003-09-02 2006-03-10 Preparation pharmaceutique comprenant un derive de la pyrimidine-a-one enrobe d'un polymere enterique

Country Status (30)

Country Link
US (2) US20060287346A1 (fr)
EP (1) EP1663243B1 (fr)
JP (1) JP4892346B2 (fr)
KR (1) KR101115984B1 (fr)
CN (2) CN1874778B (fr)
AR (1) AR045547A1 (fr)
AT (1) ATE422889T1 (fr)
AU (1) AU2004268376B2 (fr)
BR (1) BRPI0414038A (fr)
CA (1) CA2537178C (fr)
CY (1) CY1108953T1 (fr)
DE (1) DE602004019547D1 (fr)
DK (1) DK1663243T3 (fr)
ES (1) ES2319124T3 (fr)
GB (1) GB0320522D0 (fr)
HR (1) HRP20090147T3 (fr)
IL (1) IL173910A (fr)
IS (1) IS2677B (fr)
MA (1) MA28033A1 (fr)
MX (1) MXPA06002436A (fr)
MY (1) MY139165A (fr)
NO (1) NO333744B1 (fr)
NZ (1) NZ545453A (fr)
PL (1) PL1663243T3 (fr)
PT (1) PT1663243E (fr)
RU (1) RU2359660C2 (fr)
SI (1) SI1663243T1 (fr)
TW (1) TWI343257B (fr)
WO (1) WO2005021002A1 (fr)
ZA (1) ZA200601599B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0320522D0 (en) * 2003-09-02 2003-10-01 Glaxo Group Ltd Formulation
EP2977452A3 (fr) 2007-05-11 2016-05-25 Thomas Jefferson University Procédés de traitement et de prévention de maladies et de troubles neurodégénératifs
CN101687009A (zh) 2007-05-11 2010-03-31 宾夕法尼亚大学理事会 治疗皮肤溃疡的方法
KR101580656B1 (ko) 2009-04-24 2015-12-30 아이슈티카 피티와이 리미티드 디클로페낙의 신규 제형
ES2847883T3 (es) 2010-12-17 2021-08-04 Glaxo Group Ltd Uso de inhibidores de LP-PLA2 en el tratamiento y prevención de enfermedades oculares
WO2013082275A1 (fr) 2011-11-30 2013-06-06 Trustees Of Boston College Inhibiteurs de phosphodiestérases 11 (pde11) et procédés d'utilisation pour augmenter la production de cortisol
US9526734B2 (en) 2014-06-09 2016-12-27 Iceutica Pty Ltd. Formulation of meloxicam
CN106536525B (zh) 2014-07-22 2019-05-03 葛兰素史密斯克莱知识产权发展有限公司 化合物

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3619570C1 (en) 1986-06-11 1987-10-29 Kneipp Werke Kneipp Mittel Zen Coated garlic tablet
US4971805A (en) * 1987-12-23 1990-11-20 Teysan Pharmaceuticals Co., Ltd. Slow-releasing granules and long acting mixed granules comprising the same
IT1227899B (it) * 1988-12-23 1991-05-14 Poli Ind Chimica Spa Rivestimento totale o parziale di principi attivi farmaceutici e relative composizioni
TW209174B (fr) * 1991-04-19 1993-07-11 Takeda Pharm Industry Co Ltd
JPH07223970A (ja) * 1994-02-10 1995-08-22 Tanabe Seiyaku Co Ltd 消化管内適所放出製剤
JP2917799B2 (ja) * 1994-03-11 1999-07-12 田辺製薬株式会社 消化管内適所放出型製剤
JP3185206B2 (ja) * 1995-07-20 2001-07-09 田辺製薬株式会社 消化管下部放出型被覆カプセル製剤
SG80553A1 (en) 1995-07-20 2001-05-22 Tanabe Seiyaku Co Pharmaceutical preparation in form of coated capsule releasable at lower part of digestive tract
AU717817B2 (en) * 1996-06-06 2000-04-06 Bifodan A/S Enteric coating, comprising alginic acid, for an oral preparation
DE59702733D1 (de) * 1996-08-15 2001-01-11 Losan Pharma Gmbh Gut schluckbare orale arzneiform
US6296876B1 (en) * 1997-10-06 2001-10-02 Isa Odidi Pharmaceutical formulations for acid labile substances
DE69934505T2 (de) * 1998-05-18 2007-10-04 Takeda Pharmaceutical Co. Ltd. Im munde zerfallende tablette enthaltend ein benzimidazole
CZ20011629A3 (cs) 1998-11-12 2001-12-12 Smithkline Beecham Plc Farmaceutický prostředek pro upravené uvolňování senzitizéru inzulínu a jiných antidiabetických přípravků
US6268385B1 (en) * 1999-08-26 2001-07-31 Robert R. Whittle Dry blend pharmaceutical formulations
NZ520752A (en) * 2000-02-16 2004-03-26 Smithkline Beecham P Pyrimidine-4-one derivatives as LDL-PLA2 inhibitors
AUPQ672800A0 (en) * 2000-04-06 2000-05-04 Natraherbal Pty Ltd Garlic supplement for deodoriser
KR100786927B1 (ko) * 2000-06-28 2007-12-17 스미스클라인비이참피이엘시이 습식 분쇄방법
ES2366430T3 (es) 2001-06-20 2011-10-20 Takeda Pharmaceutical Company Limited Método para fabricar comprimidos.
JP5138856B2 (ja) * 2001-06-20 2013-02-06 武田薬品工業株式会社 錠剤の製造方法
RU2203671C1 (ru) * 2002-03-25 2003-05-10 Общество С Ограниченной Ответственностью "Научно-Технологическая Фармацевтическая Фирма "Полисан" Противовирусный лекарственный препарат для перорального применения
GB0320522D0 (en) * 2003-09-02 2003-10-01 Glaxo Group Ltd Formulation

Also Published As

Publication number Publication date
NO333744B1 (no) 2013-09-09
CY1108953T1 (el) 2014-07-02
RU2006110546A (ru) 2006-08-10
BRPI0414038A (pt) 2006-10-24
DK1663243T3 (da) 2009-05-04
IL173910A0 (en) 2006-07-05
NZ545453A (en) 2009-12-24
TW200517113A (en) 2005-06-01
GB0320522D0 (en) 2003-10-01
TWI343257B (en) 2011-06-11
SI1663243T1 (sl) 2009-06-30
CN1874778A (zh) 2006-12-06
DE602004019547D1 (de) 2009-04-02
CN1874778B (zh) 2011-06-22
EP1663243A1 (fr) 2006-06-07
PL1663243T3 (pl) 2009-07-31
MXPA06002436A (es) 2006-06-20
PT1663243E (pt) 2009-04-27
CN102204891B (zh) 2013-08-21
KR20060118422A (ko) 2006-11-23
US20090306113A1 (en) 2009-12-10
ES2319124T3 (es) 2009-05-04
EP1663243B1 (fr) 2009-02-18
AU2004268376A1 (en) 2005-03-10
IS2677B (is) 2010-09-15
HRP20090147T3 (hr) 2009-04-30
ATE422889T1 (de) 2009-03-15
ZA200601599B (en) 2007-05-30
WO2005021002A1 (fr) 2005-03-10
JP4892346B2 (ja) 2012-03-07
HK1091734A1 (en) 2007-01-26
KR101115984B1 (ko) 2012-03-13
MY139165A (en) 2009-08-28
IL173910A (en) 2010-11-30
AR045547A1 (es) 2005-11-02
US8772303B2 (en) 2014-07-08
CA2537178C (fr) 2013-03-19
JP2007504195A (ja) 2007-03-01
IS8366A (is) 2006-03-20
RU2359660C2 (ru) 2009-06-27
US20060287346A1 (en) 2006-12-21
CN102204891A (zh) 2011-10-05
AU2004268376B2 (en) 2010-04-22
NO20061514L (no) 2006-04-03
CA2537178A1 (fr) 2005-03-10

Similar Documents

Publication Publication Date Title
MA29321B1 (fr) Vaccin a base de rotavirus vivant attenue pour administration orale
HUP0104258A2 (hu) HMG-CoA reduktáz inhibítort tartalmazó stabil gyógyszerkészítmények
MXPA05001607A (es) Forma galenica para suministro de ingredientes activos dirigido al colon.
YU49202A (sh) Benzazolski derivati i njihova upotreba kao modulatora jnk
TNSN01053A1 (fr) Compositions nouvelles comprenant un agoniste partiel des recepteurs de nicotine et un agent analgesique
FR13C0062I2 (fr) Compositions pharmaceutiques comprenant du dextromethorphan et de la quinidine pour traiter des troubles neurologiques
MA26709A1 (fr) Compositions pharmaceutiques de celecoxib, leurs procedes de preparation et methodes de traitement les utilisant
SG166093A1 (en) Inhibitors of brutonæs tyrosine kinase
MA30655B1 (fr) Composes organiques.
WO2002099055A3 (fr) Cip comme modificateurs de la voie p53 et methodes d'utilisation associees
EP2101757A4 (fr) Composé pour le traitement ou la prévention de maladies en relation avec la prostate et compositions pharmaceutiques de système d'administration par le colon contenant ce composé
CY1109695T1 (el) Μικροοργανισμοι αποδομησης οξαλικου ή ενζυμα αποδομησης οξαλικου για την προληψη παθησης σχετιζομενης με οξαλικο
MA33419B1 (fr) Composés et compositions pour le traitement de maladies parasitaires
MA27509A1 (fr) Formulations a liberation prolongee contenant de la lamotrigine
DE60313004D1 (de) Alpha-7-nikotinsäure-rezeptoragonisten und statine in kombination
MA28033A1 (fr) Preparation pharmaceutique comprenant un derive de la pyrimidine-a-one enrobe d'un polymere enterique
WO2006021160A8 (fr) Système de relargage de médicament auto-émulsifiant à base de butylbenzènephtaléine, méthode de préparation et applications d’un tel système
PT1358177E (pt) Tratamento de desordens afectivas atraves da accao combinada de um agonista do receptor nicotinico e uma substancia manoaminergica
MA27021A1 (fr) Sel consistant en citrate de 5,8,14-triazatetracyclo(10.3.1.0 .0 ) -hexadeca-2(11),3,5,7,9- pentaene et compositions pharmaceutiques le contenant
HUP0002346A1 (hu) Emlősök elmezavarainak kezelésére szolgáló gyógyszerkészítmény
WO2003105753A3 (fr) Procedes et compositions pour la greffe de boucles fonctionnelles dans une proteine
MY134019A (en) Aryl oxime-piperazines useful as ccr5 antagonists
DE60008590D1 (de) Zusammensetzungen von adenosin a1 agonisten und cox2-hemmern
MA26788A1 (fr) COMPOSITIONS PHARMACEUTIQUES DESTINÉES à L'ADMINISTRATION PAR VOIE ORALE DE PHLOROGLUCINOL ET LEUR PRÉPARATION
WO2004111270A3 (fr) Expression genique differentielle dans la schizophrenie