MA29321B1 - Vaccin a base de rotavirus vivant attenue pour administration orale - Google Patents
Vaccin a base de rotavirus vivant attenue pour administration oraleInfo
- Publication number
- MA29321B1 MA29321B1 MA30201A MA30201A MA29321B1 MA 29321 B1 MA29321 B1 MA 29321B1 MA 30201 A MA30201 A MA 30201A MA 30201 A MA30201 A MA 30201A MA 29321 B1 MA29321 B1 MA 29321B1
- Authority
- MA
- Morocco
- Prior art keywords
- oral administration
- rotavirus
- live attenuated
- rotavirus vaccine
- attenuated rotavirus
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 229960005050 live attenuated rota virus Drugs 0.000 title 1
- 241000702670 Rotavirus Species 0.000 abstract 3
- 229910019142 PO4 Inorganic materials 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 2
- 239000010452 phosphate Substances 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 150000007942 carboxylates Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000012669 liquid formulation Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/15—Reoviridae, e.g. calf diarrhea virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12311—Rotavirus, e.g. rotavirus A
- C12N2720/12334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Abstract
LA PRÉSENTE INVENTION CONCERNE DES FORMULATIONS LIQUIDES DE ROTAVIRUS QUI CONVIENNENT POUR UNE ADMINISTRATION ORALE AUX NOURRISSONS HUMAINS. EN PARTICULIER, L¿INVENTION CONCERNE DES COMPOSITIONS PHARMACEUTIQUES ET DES VACCINS COMPRENANT UN ANTIGÈNE DE ROTAVIRUS, UN SUCRE ET UN CARBOXYLATE, LEUR FORMULATION AYANT UN PH COMPRIS ENTRE PH 5.0 ET PH 8.0 ET NE COMPRENANT PAS DE PHOSPHATE OU MOINS DE 5 MM DE PHOSPHATE. CETTE INVENTION DÉCRIT ÉGALEMENT DES PROCÉDÉS DE PRÉPARATION DESDITES FORMULATIONS DE ROTAVIRUS ET L¿UTILISATION DE CELLES-CI DANS LA PRÉVENTION OU LE TRAITEMENT DES MALADIES ASSOCIÉES AU ROTAVIRUS CHEZ LES HUMAINS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0503337.8A GB0503337D0 (en) | 2005-02-17 | 2005-02-17 | Compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA29321B1 true MA29321B1 (fr) | 2008-03-03 |
Family
ID=34385675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA30201A MA29321B1 (fr) | 2005-02-17 | 2007-09-10 | Vaccin a base de rotavirus vivant attenue pour administration orale |
Country Status (32)
| Country | Link |
|---|---|
| US (2) | US8192747B2 (fr) |
| EP (2) | EP1863526B1 (fr) |
| JP (1) | JP5118977B2 (fr) |
| KR (1) | KR101319846B1 (fr) |
| CN (2) | CN101300028B (fr) |
| AP (1) | AP2692A (fr) |
| AR (1) | AR053680A1 (fr) |
| AT (1) | ATE516044T1 (fr) |
| AU (1) | AU2006215761B2 (fr) |
| BR (1) | BRPI0608877B8 (fr) |
| CA (1) | CA2598290C (fr) |
| CY (1) | CY1111916T1 (fr) |
| DK (1) | DK1863526T3 (fr) |
| EA (1) | EA012046B1 (fr) |
| ES (1) | ES2369246T3 (fr) |
| GB (1) | GB0503337D0 (fr) |
| HR (1) | HRP20110668T1 (fr) |
| IL (1) | IL184802A0 (fr) |
| MA (1) | MA29321B1 (fr) |
| MX (1) | MX2007010075A (fr) |
| MY (1) | MY145790A (fr) |
| NO (1) | NO341789B1 (fr) |
| NZ (1) | NZ560314A (fr) |
| PE (1) | PE20061094A1 (fr) |
| PL (1) | PL1863526T3 (fr) |
| PT (1) | PT1863526E (fr) |
| SI (1) | SI1863526T1 (fr) |
| TW (1) | TWI358303B (fr) |
| UA (1) | UA91044C2 (fr) |
| UY (1) | UY29377A1 (fr) |
| WO (1) | WO2006087205A1 (fr) |
| ZA (1) | ZA200706668B (fr) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2008014391A (es) * | 2006-05-12 | 2009-03-06 | Bharat Biotech Int Ltd | Una composicion util como vacuna. |
| EP2197283B1 (fr) * | 2007-09-25 | 2013-07-17 | Aridis Pharmaceuticals | Formulations pour la préservation de rotavirus |
| EP2236617A1 (fr) | 2009-03-31 | 2010-10-06 | Leukocare Ag | Procédés de stérilisation de terminal de compositions biofonctionnelles |
| CA3121654A1 (fr) | 2009-05-12 | 2010-11-18 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, Centers For Disease Control And Prevention | Nouvelles souches de rotavirus humain et nouveaux vaccins |
| CN101972475B (zh) * | 2010-04-12 | 2014-04-09 | 李建平 | 一种细菌多糖-蛋白结合疫苗及其制备方法 |
| CN101863966B (zh) * | 2010-05-21 | 2012-10-03 | 中国人民解放军第三军医大学 | 抗轮状病毒药物作用靶标及其构建方法和应用方法 |
| EA030970B8 (ru) | 2010-09-24 | 2019-01-31 | Юниверсити Оф Флорида Рисёч Фаундейшн, Инк. | Композиция для восстановления функции тонкого кишечника, способы ее приготовления и применения |
| EP2471554A1 (fr) | 2010-12-28 | 2012-07-04 | Hexal AG | Formulation pharmaceutique comprenant un médicament biopharmaceutique |
| WO2012103464A2 (fr) * | 2011-01-28 | 2012-08-02 | Brian Pulliam | Préparation de vaccin sous forme de mince film oral |
| CN103747800A (zh) * | 2011-04-28 | 2014-04-23 | 国际医学基金会 | 液体疫苗制剂 |
| CN102349932B (zh) * | 2011-10-12 | 2012-12-26 | 刘壮华 | 一种治疗息肉的药物制剂 |
| WO2013105105A2 (fr) * | 2012-01-13 | 2013-07-18 | Serum Institute Of India Ltd. | Nouvelles compositions de vaccins viraux et méthodes de préparation de tels vaccins |
| EA034014B1 (ru) * | 2012-02-08 | 2019-12-19 | Юниверсити Оф Флорида Рисёч Фаундейшн, Инк. | Способ лечения субъекта с диареей, вызванной ротавирусом |
| BR112014020930A2 (pt) | 2012-03-05 | 2017-06-27 | De Staat Der Nederlanden Vert Door De Mini Van Vws Miniie Van Volksgezondheid Welzijn En Sport | método para produzir uma formulação seca de um agente biofármaco, e, formulação de um agente biofármaco |
| BR112014026407B1 (pt) * | 2012-04-23 | 2020-12-22 | Bharat Biotech International Limited | formulação de vacina líquida |
| US9314519B2 (en) | 2012-08-21 | 2016-04-19 | Intervet Inc. | Liquid stable virus vaccines |
| EP4417256A3 (fr) | 2013-03-11 | 2024-10-23 | University of Florida Research Foundation, Inc. | Matériaux et procédés pour améliorer la fonction pulmonaire |
| US9480739B2 (en) * | 2013-03-15 | 2016-11-01 | Intervet Inc. | Bovine virus vaccines that are liquid stable |
| US9393298B2 (en) | 2013-03-15 | 2016-07-19 | Intervet Inc. | Liquid stable bovine virus vaccines |
| CN103316336B (zh) * | 2013-05-31 | 2015-01-28 | 北京科兴中维生物技术有限公司 | 一种适于口服的轮状病毒疫苗 |
| CN103316335B (zh) * | 2013-05-31 | 2014-11-12 | 北京科兴生物制品有限公司 | 一种适于口服的脊髓灰质炎病毒疫苗 |
| EP3021833B2 (fr) * | 2013-07-19 | 2022-03-30 | Hexal Aktiengesellschaft | Procédés et formulations qui permettent à la modulation de réponses immunitaires associées à l'administration d'un médicament biopharmaceutique |
| AR097762A1 (es) | 2013-09-27 | 2016-04-13 | Intervet Int Bv | Formulaciones secas de vacunas que son estables a temperatura ambiente |
| EP3053594A4 (fr) * | 2013-10-03 | 2017-05-10 | Nitto Denko Corporation | Préparation de vaccin antigrippal séchée, et procédé pour produire une préparation de vaccin antigrippal séchée |
| AR099470A1 (es) | 2014-02-17 | 2016-07-27 | Intervet Int Bv | Vacunas de virus de aves de corral líquidas |
| TWI670085B (zh) | 2014-02-19 | 2019-09-01 | 荷蘭商英特威國際公司 | 液體穩定之豬病毒疫苗 |
| CN104524562A (zh) * | 2014-12-08 | 2015-04-22 | 武汉生物制品研究所有限责任公司 | 口服六价重配轮状病毒活疫苗 |
| WO2017062246A1 (fr) | 2015-10-05 | 2017-04-13 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Souche de rotavirus humain g9p[6] et utilisation comme vaccin |
| EP3389786A4 (fr) * | 2015-12-18 | 2019-08-21 | Merck Sharp & Dohme Corp. | Formulations thermiquement stables de vaccin anti-rotavirus et leurs méthodes d'utilisation |
| MA44557B1 (fr) | 2016-06-16 | 2021-11-30 | Bharat Biotech Int Ltd | Vaccin contre le rotavirus sans tampon, stable en milieu acide, et d'un faible volume de dose à administrer |
| GB201614799D0 (en) * | 2016-09-01 | 2016-10-19 | Glaxosmithkline Biologicals Sa | Compositions |
| AU2019254473A1 (en) * | 2018-04-16 | 2020-12-03 | Merck Patent Gmbh | Additives for protein formulations to improve thermal stability |
| CN110946871A (zh) * | 2019-12-12 | 2020-04-03 | 浙江华康药业股份有限公司 | 槐糖在制备预防和治疗肥胖产品中的应用及对应产品 |
| CN115531364B (zh) * | 2021-06-30 | 2024-02-23 | 中国科学技术大学 | 预防或治疗轮状病毒感染的微生物代谢物制剂及其用途 |
| CN113994925B (zh) * | 2021-12-30 | 2022-04-26 | 北京赛尔富森生物科技有限公司 | 一种轮状病毒攻毒动物模型及其建立方法 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2505657A1 (fr) | 1981-05-13 | 1982-11-19 | Pasteur Institut | Perfectionnements apportes aux agents de stabilisation de virus vivants pour la preparation de vaccins, et vaccins stabilises contenant lesdits agents de stabilisation |
| US4436727A (en) | 1982-05-26 | 1984-03-13 | Ribi Immunochem Research, Inc. | Refined detoxified endotoxin product |
| SE8205892D0 (sv) | 1982-10-18 | 1982-10-18 | Bror Morein | Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin |
| US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| CA1331443C (fr) | 1987-05-29 | 1994-08-16 | Charlotte A. Kensil | Adjuvant a saponine |
| JP2849632B2 (ja) | 1988-04-08 | 1999-01-20 | 社団法人北里研究所 | ワクチン製剤 |
| US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
| ES2121841T3 (es) | 1990-11-16 | 1998-12-16 | Childrens Hosp Medical Center | Una vacuna para proporcionar proteccion inmunologica contra enfermedades de rotavirus en humanos. |
| NZ240818A (en) * | 1990-12-14 | 1993-08-26 | Mcneil Ppc Inc | Liquid sucralose concentrate compositions containing preservative, buffer and liquid |
| HUT67006A (en) * | 1991-08-05 | 1995-01-30 | Sterling Winthrop Inc | Buffered composition containing mammalian superoxide-dismutase/polyethylene glycol coniugate |
| ZA929870B (en) | 1991-12-23 | 1993-08-18 | Duphar Int Res | Adjuvants |
| IT1253009B (it) | 1991-12-31 | 1995-07-10 | Sclavo Ricerca S R L | Mutanti immunogenici detossificati della tossina colerica e della tossina lt, loro preparazione ed uso per la preparazione di vaccini |
| CA2138997C (fr) | 1992-06-25 | 2003-06-03 | Jean-Paul Prieels | Composition vaccinale qui contient des adjuvants |
| SG48309A1 (en) | 1993-03-23 | 1998-04-17 | Smithkline Beecham Biolog | Vaccine compositions containing 3-0 deacylated monophosphoryl lipid a |
| JP3967769B2 (ja) | 1993-11-17 | 2007-08-29 | オーエム・ファルマ | グルコサミンジサッカライド、それらの製造法、それらを含む医薬組成物およびそれらの使用 |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| US6019982A (en) | 1994-08-26 | 2000-02-01 | The Administrators Of The Tulane Educational Fund | Mutant enterotoxin effective as a non-toxic oral adjuvant |
| AUPM873294A0 (en) | 1994-10-12 | 1994-11-03 | Csl Limited | Saponin preparations and use thereof in iscoms |
| GB9620795D0 (en) | 1996-10-05 | 1996-11-20 | Smithkline Beecham Plc | Vaccines |
| UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| US5932223A (en) * | 1996-09-26 | 1999-08-03 | Merck & Co., Inc. | Rotavirus vaccine formulations |
| US6616931B1 (en) * | 1996-09-26 | 2003-09-09 | Merck & Co., Inc. | Rotavirus vaccine formulations |
| US6403098B1 (en) * | 1996-09-26 | 2002-06-11 | Merck & Co., Inc. | Rotavirus vaccine formulations |
| EP1891968A3 (fr) | 1996-09-26 | 2008-09-03 | Merck & Co., Inc. | Formulations de vaccins à rotavirus |
| ES2227825T3 (es) | 1997-04-01 | 2005-04-01 | Corixa Corporation | Composiciones inmunologicas aduvantes acuosas de monofosforil lipido a. |
| WO1998056415A1 (fr) | 1997-06-11 | 1998-12-17 | Aquila Biopharmaceuticals, Inc. | Saponines purifiees servant d'adjuvants oraux |
| GB9718901D0 (en) | 1997-09-05 | 1997-11-12 | Smithkline Beecham Biolog | Vaccine |
| AU1145699A (en) | 1997-09-05 | 1999-03-22 | Smithkline Beecham Biologicals (Sa) | Oil in water emulsions containing saponins |
| GB9725084D0 (en) * | 1997-11-28 | 1998-01-28 | Medeva Europ Ltd | Vaccine compositions |
| US6919076B1 (en) * | 1998-01-20 | 2005-07-19 | Pericor Science, Inc. | Conjugates of agents and transglutaminase substrate linking molecules |
| AU7924598A (en) | 1998-06-08 | 1999-12-30 | Sca Emballage France | Fast flattening packaging |
| US7157092B1 (en) | 1998-06-30 | 2007-01-02 | Om Pharma | Acyl pseudodipeptides, preparation method and pharmaceutical compositions containing same |
| SK287261B6 (sk) * | 1999-08-17 | 2010-04-07 | Smithkline Beecham Biologicals S.A. | Oslabená ľudská rotavírusová populácia, spôsob jej výroby, vakcínový prostriedok s jej obsahom a jej použitie |
| AU1581400A (en) | 1999-12-22 | 2001-07-03 | Om Pharma | Acyl pseudopeptides bearing a functionalised auxiliary spacer |
| CA2398428C (fr) | 2000-01-28 | 2015-09-08 | Albert Kapikian | Compositions et procede pour prevenir la reactogenicite associee a l'administration de compositions de rotavirus vivants immunogenes |
-
2005
- 2005-02-17 GB GBGB0503337.8A patent/GB0503337D0/en not_active Ceased
-
2006
- 2006-02-15 DK DK06707035.9T patent/DK1863526T3/da active
- 2006-02-15 JP JP2007555532A patent/JP5118977B2/ja not_active Expired - Lifetime
- 2006-02-15 AT AT06707035T patent/ATE516044T1/de active
- 2006-02-15 CA CA2598290A patent/CA2598290C/fr not_active Expired - Lifetime
- 2006-02-15 SI SI200631128T patent/SI1863526T1/sl unknown
- 2006-02-15 CN CN200680005318.2A patent/CN101300028B/zh not_active Expired - Lifetime
- 2006-02-15 AR ARP060100551A patent/AR053680A1/es not_active Application Discontinuation
- 2006-02-15 PE PE2006000184A patent/PE20061094A1/es not_active Application Discontinuation
- 2006-02-15 CN CN2013103024516A patent/CN103357005A/zh active Pending
- 2006-02-15 MX MX2007010075A patent/MX2007010075A/es active IP Right Grant
- 2006-02-15 BR BRPI0608877A patent/BRPI0608877B8/pt active IP Right Grant
- 2006-02-15 AP AP2007004087A patent/AP2692A/xx active
- 2006-02-15 EP EP06707035A patent/EP1863526B1/fr not_active Expired - Lifetime
- 2006-02-15 HR HR20110668T patent/HRP20110668T1/hr unknown
- 2006-02-15 PT PT06707035T patent/PT1863526E/pt unknown
- 2006-02-15 NZ NZ560314A patent/NZ560314A/en not_active IP Right Cessation
- 2006-02-15 ES ES06707035T patent/ES2369246T3/es not_active Expired - Lifetime
- 2006-02-15 PL PL06707035T patent/PL1863526T3/pl unknown
- 2006-02-15 TW TW095105102A patent/TWI358303B/zh not_active IP Right Cessation
- 2006-02-15 UY UY29377A patent/UY29377A1/es unknown
- 2006-02-15 UA UAA200708765A patent/UA91044C2/uk unknown
- 2006-02-15 US US11/816,443 patent/US8192747B2/en active Active
- 2006-02-15 EA EA200701519A patent/EA012046B1/ru not_active IP Right Cessation
- 2006-02-15 EP EP10180343A patent/EP2322211A1/fr not_active Withdrawn
- 2006-02-15 MY MYPI20060654A patent/MY145790A/en unknown
- 2006-02-15 WO PCT/EP2006/001442 patent/WO2006087205A1/fr not_active Ceased
- 2006-02-15 KR KR1020077021142A patent/KR101319846B1/ko not_active Expired - Lifetime
- 2006-02-15 AU AU2006215761A patent/AU2006215761B2/en not_active Expired
-
2007
- 2007-07-24 IL IL184802A patent/IL184802A0/en active IP Right Grant
- 2007-07-24 NO NO20073868A patent/NO341789B1/no unknown
- 2007-08-10 ZA ZA200706668A patent/ZA200706668B/xx unknown
- 2007-09-10 MA MA30201A patent/MA29321B1/fr unknown
-
2011
- 2011-10-06 CY CY20111100959T patent/CY1111916T1/el unknown
-
2012
- 2012-06-01 US US13/486,039 patent/US8821891B2/en not_active Expired - Lifetime
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MY145790A (en) | Composition | |
| EP1790340A3 (fr) | Chimotherapie combinée | |
| EP1478371A4 (fr) | Methodes et produits permettant d'ameliorer des reponses immunitaires a l'aide de compose d'imidazoquinoline | |
| MA29715B1 (fr) | Utilisation d'un virus de la grippe et d'un adjuvant de type emulsion huile dans l'eau pour induire une cellule t cd-4 et/ou ameliorer la reponse de la cellule a memoire b | |
| NL300728I1 (fr) | ||
| MA29681B1 (fr) | Formes galeniques du risedronate | |
| WO2003061578A3 (fr) | Compositions destinees a traiter ou prevenir les effets d'une attaque bioterroriste | |
| Nason et al. | Lipopolysaccharide-induced osteoclastogenesis from mononuclear precursors: a mechanism for osteolysis in chronic otitis | |
| World Health Organization | Yellow fever fact sheet:(revised in December 2009)= Aide-mémoire sur la fièvre jaune:(révisé en décembre 2009) | |
| TW200600121A (en) | Pharmaceutical dosage forms | |
| ES2356371T3 (es) | Medicamentos terapéuticos para inducir tolerancia. | |
| EP4062931A1 (fr) | Nouvelle application d'une composition immunogene ou vaccinale | |
| Ahmed et al. | The Salivary Secretion and Biochemical Composition Analysis in Patients with Helicobacter pyloriInfection | |
| Ju et al. | Alternative therapies with tacrolimus and low-dose doxycycline for oral chronic graft-versus-host disease that is resistant to topical corticosteroid medication: case report | |
| EP4313142A1 (fr) | Nouvelle application d'une composition immunogene ou vaccinale | |
| TH83579B (th) | สารผสม | |
| Jernigan | Lyme Toxins: The Primary Cause of Your Symptoms! |