MA28931B1 - Derives de purine utilises comme agonistes des recepteurs a-2a de l'adenosine - Google Patents

Derives de purine utilises comme agonistes des recepteurs a-2a de l'adenosine

Info

Publication number
MA28931B1
MA28931B1 MA29825A MA29825A MA28931B1 MA 28931 B1 MA28931 B1 MA 28931B1 MA 29825 A MA29825 A MA 29825A MA 29825 A MA29825 A MA 29825A MA 28931 B1 MA28931 B1 MA 28931B1
Authority
MA
Morocco
Prior art keywords
agonists
adenosine receptors
purine derivatives
purine
derivatives
Prior art date
Application number
MA29825A
Other languages
English (en)
Inventor
Robin Alec Fairhurst
Roger John Taylor
Paul Singh
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0423551A external-priority patent/GB0423551D0/en
Priority claimed from GB0514619A external-priority patent/GB0514619D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MA28931B1 publication Critical patent/MA28931B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
MA29825A 2004-10-22 2007-04-12 Derives de purine utilises comme agonistes des recepteurs a-2a de l'adenosine MA28931B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0423551A GB0423551D0 (en) 2004-10-22 2004-10-22 Organic compounds
GB0514619A GB0514619D0 (en) 2005-07-15 2005-07-15 Organic compounds

Publications (1)

Publication Number Publication Date
MA28931B1 true MA28931B1 (fr) 2007-10-01

Family

ID=35589070

Family Applications (1)

Application Number Title Priority Date Filing Date
MA29825A MA28931B1 (fr) 2004-10-22 2007-04-12 Derives de purine utilises comme agonistes des recepteurs a-2a de l'adenosine

Country Status (21)

Country Link
US (1) US8163754B2 (fr)
EP (2) EP2292619A1 (fr)
JP (1) JP4904279B2 (fr)
KR (1) KR20070073798A (fr)
AR (1) AR051642A1 (fr)
AU (2) AU2005298878B2 (fr)
BR (1) BRPI0517455A (fr)
CA (1) CA2582434A1 (fr)
EC (1) ECSP077404A (fr)
ES (1) ES2394453T3 (fr)
GT (1) GT200500281A (fr)
IL (1) IL182528A0 (fr)
MA (1) MA28931B1 (fr)
MX (1) MX2007004735A (fr)
NO (1) NO20072122L (fr)
NZ (1) NZ554546A (fr)
PE (2) PE20100266A1 (fr)
RU (1) RU2403253C2 (fr)
TN (1) TNSN07154A1 (fr)
TW (1) TW200630366A (fr)
WO (1) WO2006045552A1 (fr)

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GB0607953D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
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GB0607945D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
GB0607954D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
GB0607950D0 (en) 2006-04-21 2006-05-31 Novartis Ag Organic compounds
GB0607948D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
GB0607944D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
EP1889846A1 (fr) * 2006-07-13 2008-02-20 Novartis AG Dérivés de purine comme agonistes du recepteur A2a
EP1903044A1 (fr) 2006-09-14 2008-03-26 Novartis AG Derivés de l'adénosine en tant qu' agonistes du récepteur A2A
JP2010508835A (ja) * 2006-11-10 2010-03-25 ノバルティス アーゲー シクロペンテンジオールモノアセテート誘導体
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CN101827847A (zh) * 2007-10-17 2010-09-08 诺瓦提斯公司 用作腺苷a1受体配体的嘌呤衍生物
US20090181934A1 (en) * 2007-10-17 2009-07-16 Novartis Ag Organic Compounds
WO2011002917A1 (fr) 2009-06-30 2011-01-06 Pgxhealth, Llc Composés alcoxy-carbonyl-amino-alcynyle-adénosine et dérivés de ceux-ci en tant qu'agonistes de a2a r
WO2015041809A2 (fr) 2013-08-26 2015-03-26 The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone Reprogrammation cellulaire par petites molécules pour générer des cellules neuronales

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EP1805181A1 (fr) 2007-07-11
EP2292619A1 (fr) 2011-03-09
PE20100266A1 (es) 2010-04-21
US20080200483A1 (en) 2008-08-21
ECSP077404A (es) 2007-05-30
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KR20070073798A (ko) 2007-07-10
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NZ554546A (en) 2010-10-29
RU2403253C2 (ru) 2010-11-10
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TNSN07154A1 (en) 2008-11-21
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