MA29227B1 - 4-phenyltetrahydroisoquinoline substituees, leur procedes de fabrication, leur utilisation en tant que medicament et medicament les contenant - Google Patents
4-phenyltetrahydroisoquinoline substituees, leur procedes de fabrication, leur utilisation en tant que medicament et medicament les contenantInfo
- Publication number
- MA29227B1 MA29227B1 MA30050A MA30050A MA29227B1 MA 29227 B1 MA29227 B1 MA 29227B1 MA 30050 A MA30050 A MA 30050A MA 30050 A MA30050 A MA 30050A MA 29227 B1 MA29227 B1 MA 29227B1
- Authority
- MA
- Morocco
- Prior art keywords
- medicinal product
- phenyltetrahydroisoquinoline
- substitutes
- manufacturing
- methods
- Prior art date
Links
- 229940126601 medicinal product Drugs 0.000 title 2
- OSZMNJRKIPAVOS-UHFFFAOYSA-N 4-phenyl-1,2,3,4-tetrahydroisoquinoline Chemical compound C1NCC2=CC=CC=C2C1C1=CC=CC=C1 OSZMNJRKIPAVOS-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 208000009304 Acute Kidney Injury Diseases 0.000 abstract 1
- 208000033626 Renal failure acute Diseases 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 201000011040 acute kidney failure Diseases 0.000 abstract 1
- 208000012998 acute renal failure Diseases 0.000 abstract 1
- 208000020832 chronic kidney disease Diseases 0.000 abstract 1
- 208000022831 chronic renal failure syndrome Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 208000017169 kidney disease Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 208000023504 respiratory system disease Diseases 0.000 abstract 1
- 201000002859 sleep apnea Diseases 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
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- A—HUMAN NECESSITIES
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/08—Antiepileptics; Anticonvulsants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/18—Aralkyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Tropical Medicine & Parasitology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pulmonology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Transplantation (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
LA PRÉSENTE INVENTION CONCERNE DES COMPOSÉS DE FORMULE (I), DANS LAQUELLE R1 À R8, W, X ET Z ONT LES CORRESPONDANCES INDIQUÉES DANS LES REVENDICATIONS. DES MÉDICAMENTS QUI CONTIENNENT DES COMPOSÉS DE CE TYPE, S'AVÈRENT UTILES POUR LA PRÉVENTION OU LE TRAITEMENT DE DIVERSES MALADIES. LES COMPOSÉS PEUVENT AINSI ÊTRE UTILISÉS ENTRE AUTRES POUR DES TROUBLES RÉNAUX TELS QUE L'INSUFFISANCE RÉNALE AIGUË OU CHRONIQUE, POUR DES TROUBLES DU FONCTIONNEMENT BILIAIRE, ET POUR DES TROUBLES RESPIRATOIRES TELS QUE LE RONFLEMENT OU L'APNÉE DU SOMMEIL.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102005001411A DE102005001411A1 (de) | 2005-01-12 | 2005-01-12 | Substituierte 4-Phenyltetrahydroisochinoline, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, sowie sie enthaltendes Medikament |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA29227B1 true MA29227B1 (fr) | 2008-02-01 |
Family
ID=36121409
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA30050A MA29227B1 (fr) | 2005-01-12 | 2007-07-06 | 4-phenyltetrahydroisoquinoline substituees, leur procedes de fabrication, leur utilisation en tant que medicament et medicament les contenant |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US7868003B2 (fr) |
| EP (1) | EP1838315B1 (fr) |
| JP (1) | JP2008526906A (fr) |
| KR (1) | KR20070094916A (fr) |
| CN (1) | CN101184488A (fr) |
| AR (1) | AR053326A1 (fr) |
| AU (1) | AU2005324833A1 (fr) |
| BR (1) | BRPI0519854A2 (fr) |
| CA (1) | CA2594419A1 (fr) |
| CR (1) | CR9191A (fr) |
| DE (1) | DE102005001411A1 (fr) |
| DK (1) | DK1838315T3 (fr) |
| DO (1) | DOP2006000011A (fr) |
| ES (1) | ES2470980T3 (fr) |
| GT (1) | GT200600017A (fr) |
| IL (1) | IL184314A0 (fr) |
| MA (1) | MA29227B1 (fr) |
| MX (1) | MX2007008269A (fr) |
| MY (1) | MY142493A (fr) |
| NI (1) | NI200700162A (fr) |
| NO (1) | NO20074084L (fr) |
| NZ (1) | NZ556080A (fr) |
| PA (1) | PA8659501A1 (fr) |
| PT (1) | PT1838315E (fr) |
| RU (1) | RU2398766C2 (fr) |
| TN (1) | TNSN07263A1 (fr) |
| TW (1) | TW200637842A (fr) |
| UA (1) | UA88941C2 (fr) |
| UY (1) | UY29333A1 (fr) |
| WO (1) | WO2006074813A1 (fr) |
| ZA (1) | ZA200704728B (fr) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5745406B2 (ja) | 2008-09-02 | 2015-07-08 | サノフイ | 置換アミノインダン及びそのアナログ、及びその医薬使用 |
| MX381407B (es) * | 2008-12-31 | 2025-03-12 | Ardelyx Inc | Compuestos y métodos para inhibir el antiporte mediado por intercambiador de iones de sodio/iones de hidrógeno (nhe) en el tratamiento de trastornos asociados con retención de fluido o sobrecarga de sal y trastornos del tracto gastrointestinal. |
| US10543207B2 (en) * | 2008-12-31 | 2020-01-28 | Ardelyx, Inc. | Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
| US20120088737A2 (en) * | 2009-10-02 | 2012-04-12 | Ajinomoto Co., Inc | Novel acyl guanidine derivatives |
| JP5788404B2 (ja) * | 2009-12-11 | 2015-09-30 | アウトイフオンイ トヘラペウトイクス リミテッド | イミダゾリジンジオン誘導体 |
| US20130011480A1 (en) * | 2011-05-05 | 2013-01-10 | Rosenberg Mark A | Cytotoxic therapy by proton flux modulation |
| HRP20191000T1 (hr) | 2013-04-12 | 2019-09-20 | Ardelyx, Inc. | Spojevi za vezanje nhe3 i metode inhibiranja transporta fosfata |
| RU2703456C2 (ru) * | 2014-07-25 | 2019-10-17 | Тайсо Фармасьютикал Ко., Лтд. | Фенилтетрагидроизохинолиновое соединение, замещенное гетероарилом |
| JP6903923B2 (ja) * | 2016-01-22 | 2021-07-14 | 大正製薬株式会社 | ヘテロアリールで置換されたフェニルテトラヒドロイソキノリン化合物を有効成分として含有する医薬 |
| MX395405B (es) | 2017-01-09 | 2025-03-25 | Ardelyx Inc | Compuestos útiles para tratar trastornos del tracto gastrointestinal. |
| MX2019008171A (es) | 2017-01-09 | 2020-02-05 | Ardelyx Inc | Inhibidores del antiporte mediado por nhe. |
| CN114716458A (zh) * | 2021-01-04 | 2022-07-08 | 上海济煜医药科技有限公司 | 四氢异喹啉类化合物 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19633966A1 (de) | 1996-08-22 | 1998-02-26 | Hoechst Ag | Phenylsubstituierte Alkenylcarbonsäure-guanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE19945302A1 (de) | 1999-09-22 | 2001-03-29 | Merck Patent Gmbh | Biphenylderivate als NHE-3-Inhibitoren |
| NZ519146A (en) | 1999-11-03 | 2004-02-27 | Albany Molecular Res Inc | 4-phenyl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin |
| MXPA02004330A (es) * | 1999-11-03 | 2004-07-30 | Albany Molecular Res Inc | Tetrahidroisoquinolinas aril-y heteroaril-sustituidas y uso de las mismas para bloquear la recaptacion de norepinefrina, dopamina y serotonina.. |
| DE19960204A1 (de) | 1999-12-14 | 2001-06-28 | Aventis Pharma Gmbh | Substituierte Norlbornylamino-Derivate, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE10015248A1 (de) | 2000-03-28 | 2001-10-04 | Merck Patent Gmbh | Bisamidino-Verbindungen als NHE-3 Inhibitoren |
| DE10019062A1 (de) | 2000-04-18 | 2001-10-25 | Merck Patent Gmbh | 2-Guanidino-4-aryl-chinazoline als NHE-3 Inhibitoren |
| EP1453810B1 (fr) * | 2001-12-05 | 2009-03-18 | Sanofi-Aventis Deutschland GmbH | 4-phenyltetrahydroisoquinoleine, son procede de production, son utilisation comme medicament, et medicament la contenant |
| DE10163914A1 (de) | 2001-12-22 | 2003-07-03 | Aventis Pharma Gmbh | Substituierte 4-Phenyltetrahydroisochinolinium-Salze, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, sowie sie enthaltendes Medikament |
| DE10312963A1 (de) * | 2003-03-24 | 2004-10-07 | Aventis Pharma Deutschland Gmbh | Substituierte 4-Phenyltetrahydroisochinoline, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, sowie sie enthaltendes Medikament |
-
2005
- 2005-01-12 DE DE102005001411A patent/DE102005001411A1/de not_active Withdrawn
- 2005-12-30 AU AU2005324833A patent/AU2005324833A1/en not_active Abandoned
- 2005-12-30 MX MX2007008269A patent/MX2007008269A/es active IP Right Grant
- 2005-12-30 NZ NZ556080A patent/NZ556080A/en not_active IP Right Cessation
- 2005-12-30 CN CNA2005800465296A patent/CN101184488A/zh active Pending
- 2005-12-30 DK DK05823573.0T patent/DK1838315T3/da active
- 2005-12-30 JP JP2007550712A patent/JP2008526906A/ja not_active Abandoned
- 2005-12-30 WO PCT/EP2005/014127 patent/WO2006074813A1/fr not_active Ceased
- 2005-12-30 CA CA002594419A patent/CA2594419A1/fr not_active Abandoned
- 2005-12-30 EP EP05823573.0A patent/EP1838315B1/fr not_active Expired - Lifetime
- 2005-12-30 PT PT58235730T patent/PT1838315E/pt unknown
- 2005-12-30 BR BRPI0519854-2A patent/BRPI0519854A2/pt not_active IP Right Cessation
- 2005-12-30 ES ES05823573.0T patent/ES2470980T3/es not_active Expired - Lifetime
- 2005-12-30 RU RU2007130706/04A patent/RU2398766C2/ru not_active IP Right Cessation
- 2005-12-30 KR KR1020077015974A patent/KR20070094916A/ko not_active Withdrawn
- 2005-12-30 UA UAA200709180A patent/UA88941C2/ru unknown
-
2006
- 2006-01-10 TW TW095100824A patent/TW200637842A/zh unknown
- 2006-01-10 AR ARP060100092A patent/AR053326A1/es not_active Application Discontinuation
- 2006-01-11 GT GT200600017A patent/GT200600017A/es unknown
- 2006-01-11 PA PA20068659501A patent/PA8659501A1/es unknown
- 2006-01-11 MY MYPI20060103A patent/MY142493A/en unknown
- 2006-01-12 DO DO2006000011A patent/DOP2006000011A/es unknown
- 2006-01-12 UY UY29333A patent/UY29333A1/es unknown
-
2007
- 2007-06-14 ZA ZA200704728A patent/ZA200704728B/en unknown
- 2007-06-19 CR CR9191A patent/CR9191A/es not_active Application Discontinuation
- 2007-06-21 NI NI200700162A patent/NI200700162A/es unknown
- 2007-07-01 IL IL184314A patent/IL184314A0/en unknown
- 2007-07-06 MA MA30050A patent/MA29227B1/fr unknown
- 2007-07-11 US US11/776,041 patent/US7868003B2/en not_active Expired - Fee Related
- 2007-07-11 TN TNP2007000263A patent/TNSN07263A1/en unknown
- 2007-08-07 NO NO20074084A patent/NO20074084L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CR9191A (es) | 2007-10-04 |
| RU2398766C2 (ru) | 2010-09-10 |
| JP2008526906A (ja) | 2008-07-24 |
| CA2594419A1 (fr) | 2006-07-20 |
| CN101184488A (zh) | 2008-05-21 |
| MY142493A (en) | 2010-11-30 |
| KR20070094916A (ko) | 2007-09-27 |
| TW200637842A (en) | 2006-11-01 |
| AR053326A1 (es) | 2007-05-02 |
| US20080058328A1 (en) | 2008-03-06 |
| UA88941C2 (ru) | 2009-12-10 |
| NZ556080A (en) | 2009-08-28 |
| NI200700162A (es) | 2008-04-21 |
| NO20074084L (no) | 2007-09-28 |
| UY29333A1 (es) | 2006-08-31 |
| ZA200704728B (en) | 2008-07-30 |
| AU2005324833A1 (en) | 2006-07-20 |
| DE102005001411A1 (de) | 2006-07-27 |
| WO2006074813A1 (fr) | 2006-07-20 |
| GT200600017A (es) | 2006-08-28 |
| DOP2006000011A (es) | 2006-07-15 |
| TNSN07263A1 (en) | 2008-12-31 |
| DK1838315T3 (da) | 2014-06-16 |
| PA8659501A1 (es) | 2006-09-08 |
| EP1838315A1 (fr) | 2007-10-03 |
| IL184314A0 (en) | 2007-10-31 |
| MX2007008269A (es) | 2008-01-16 |
| PT1838315E (pt) | 2014-05-26 |
| RU2007130706A (ru) | 2009-02-20 |
| ES2470980T3 (es) | 2014-06-24 |
| EP1838315B1 (fr) | 2014-03-12 |
| BRPI0519854A2 (pt) | 2009-03-24 |
| US7868003B2 (en) | 2011-01-11 |
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