MA27997A1 - Composes et compositions inhibiteurs de l'activite du recepteur tyrosine kinase - Google Patents

Composes et compositions inhibiteurs de l'activite du recepteur tyrosine kinase

Info

Publication number
MA27997A1
MA27997A1 MA28818A MA28818A MA27997A1 MA 27997 A1 MA27997 A1 MA 27997A1 MA 28818 A MA28818 A MA 28818A MA 28818 A MA28818 A MA 28818A MA 27997 A1 MA27997 A1 MA 27997A1
Authority
MA
Morocco
Prior art keywords
compounds
tyrosine kinase
receptor activity
kinase receptor
inhibiting tyrosine
Prior art date
Application number
MA28818A
Other languages
English (en)
Inventor
Dai Cheng
Qiang Ding
Dong Han
Nathanael Schiander Gray
Guobao Zhang
Original Assignee
Irm Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Irm Llc filed Critical Irm Llc
Publication of MA27997A1 publication Critical patent/MA27997A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne une nouvelle catégorie de composés, des compositions pharmaceutiques contenant ces composés et des méthodes pour utiliser ces composés dans le traitement ou la prévention de maladies ou de troubles associés à l'activité kinase cSRC, Lck, FGFR3, Flt3, TrkB, Bmx et/ou PFGFR$g(a).
MA28818A 2003-08-15 2006-02-17 Composes et compositions inhibiteurs de l'activite du recepteur tyrosine kinase MA27997A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US49540603P 2003-08-15 2003-08-15
US52435703P 2003-11-21 2003-11-21
US56536704P 2004-04-26 2004-04-26

Publications (1)

Publication Number Publication Date
MA27997A1 true MA27997A1 (fr) 2006-07-03

Family

ID=34198974

Family Applications (1)

Application Number Title Priority Date Filing Date
MA28818A MA27997A1 (fr) 2003-08-15 2006-02-17 Composes et compositions inhibiteurs de l'activite du recepteur tyrosine kinase

Country Status (16)

Country Link
US (2) US20050124637A1 (fr)
EP (1) EP1656378A4 (fr)
JP (1) JP2007502776A (fr)
AU (2) AU2004264419B2 (fr)
BR (1) BRPI0413563A (fr)
CA (1) CA2535620A1 (fr)
CO (1) CO5680404A2 (fr)
EC (1) ECSP066365A (fr)
IL (1) IL173392A0 (fr)
IS (1) IS8345A (fr)
MA (1) MA27997A1 (fr)
MX (1) MXPA06001758A (fr)
NO (1) NO20061074L (fr)
SG (1) SG145748A1 (fr)
TN (1) TNSN06053A1 (fr)
WO (1) WO2005016528A2 (fr)

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EP1656378A4 (fr) 2011-05-11
US20050124637A1 (en) 2005-06-09
CA2535620A1 (fr) 2005-02-24
NO20061074L (no) 2006-03-06
TNSN06053A1 (en) 2007-10-03
ECSP066365A (es) 2006-08-30
AU2004264419A1 (en) 2005-02-24
WO2005016528A3 (fr) 2005-05-12
MXPA06001758A (es) 2006-08-11
BRPI0413563A (pt) 2006-10-17
IL173392A0 (en) 2006-06-11
AU2004264419B2 (en) 2009-01-15
WO2005016528A2 (fr) 2005-02-24
IS8345A (is) 2006-03-09
US20110092491A1 (en) 2011-04-21
EP1656378A2 (fr) 2006-05-17
CO5680404A2 (es) 2006-09-29
AU2009201480A1 (en) 2009-05-14
JP2007502776A (ja) 2007-02-15
SG145748A1 (en) 2008-09-29

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