MA29447B1 - FORMES CRISTALLINES ANHYDRES DE N-[1-(2-ETHOXYETHYL)-5-(N-ETHYL-N-METHYLAMINO)-7-(4-METHYLPYRIDINE-2-YL-AMINO)-1H-PYRAZOLO [4,3-d] PYRIMIDINE-3-CARBONYL] METHANESULFONAMIDE - Google Patents

FORMES CRISTALLINES ANHYDRES DE N-[1-(2-ETHOXYETHYL)-5-(N-ETHYL-N-METHYLAMINO)-7-(4-METHYLPYRIDINE-2-YL-AMINO)-1H-PYRAZOLO [4,3-d] PYRIMIDINE-3-CARBONYL] METHANESULFONAMIDE

Info

Publication number: MA29447B1
Authority: MA; Morocco
Prior art keywords: methanesulfonamide; methylpyridin; pyrazolo; ethoxyethyl; methylamino
Prior art date: 2005-05-12

Application number

MA30362A

Other languages

English (en)

Inventor

David Andrew Entwistle

Peter Vallance Marshall

Stefan Colin John Taylor

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-05-12

Filing date

2007-11-12

Publication date

2008-05-02

2007-11-12 Application filed by Pfizer filed Critical Pfizer

2008-05-02 Publication of MA29447B1 publication Critical patent/MA29447B1/fr

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Diabetes (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Endocrinology (AREA)
Obesity (AREA)
Reproductive Health (AREA)
Hematology (AREA)
Pulmonology (AREA)
Urology & Nephrology (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Psychiatry (AREA)
Orthopedic Medicine & Surgery (AREA)
Ophthalmology & Optometry (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Gynecology & Obstetrics (AREA)
Psychology (AREA)
Emergency Medicine (AREA)
Vascular Medicine (AREA)
Child & Adolescent Psychology (AREA)
Pregnancy & Childbirth (AREA)

MA30362A 2005-05-12 2007-11-12 FORMES CRISTALLINES ANHYDRES DE N-[1-(2-ETHOXYETHYL)-5-(N-ETHYL-N-METHYLAMINO)-7-(4-METHYLPYRIDINE-2-YL-AMINO)-1H-PYRAZOLO [4,3-d] PYRIMIDINE-3-CARBONYL] METHANESULFONAMIDE MA29447B1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US68044505P	2005-05-12	2005-05-12
US68171105P	2005-05-17	2005-05-17

Publications (1)

Publication Number	Publication Date
MA29447B1 true MA29447B1 (fr)	2008-05-02

Family

ID=37106941

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA30362A MA29447B1 (fr)	2005-05-12	2007-11-12	FORMES CRISTALLINES ANHYDRES DE N-[1-(2-ETHOXYETHYL)-5-(N-ETHYL-N-METHYLAMINO)-7-(4-METHYLPYRIDINE-2-YL-AMINO)-1H-PYRAZOLO [4,3-d] PYRIMIDINE-3-CARBONYL] METHANESULFONAMIDE

Country Status (23)

Country	Link
US (3)	US8227475B2 (fr)
EP (1)	EP1881985B1 (fr)
JP (2)	JP4271695B2 (fr)
KR (1)	KR100939890B1 (fr)
AT (1)	ATE493413T1 (fr)
AU (1)	AU2006245416B2 (fr)
BR (1)	BRPI0609225A2 (fr)
CA (1)	CA2608018C (fr)
CR (1)	CR9505A (fr)
CY (1)	CY1111171T1 (fr)
DE (1)	DE602006019231D1 (fr)
DK (1)	DK1881985T3 (fr)
EA (1)	EA012577B1 (fr)
IL (1)	IL186693A (fr)
MA (1)	MA29447B1 (fr)
MX (1)	MX2007013215A (fr)
NO (1)	NO20075258L (fr)
NZ (1)	NZ564187A (fr)
PL (1)	PL1881985T3 (fr)
PT (1)	PT1881985E (fr)
TN (1)	TNSN07414A1 (fr)
TW (1)	TWI380986B (fr)
WO (1)	WO2006120552A2 (fr)

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WO2009050554A2 (fr) *	2007-10-19	2009-04-23	Pfizer Inc.	Traitement de troubles du système nerveux central
WO2012048330A2 (fr) *	2010-10-08	2012-04-12	The Mclean Hospital Corporation	Traitement de maladie neuromotrice
WO2012131539A1 (fr)	2011-03-31	2012-10-04	Pfizer Inc.	Nouvelles pyridones bicycliques
AU2012244550C1 (en)	2011-04-21	2017-06-22	Origenis Gmbh	Pyrazolo [4, 3-d] pyrimidines useful as kinase inhibitors
WO2012172449A1 (fr)	2011-06-13	2012-12-20	Pfizer Inc.	Lactames convenant comme inhibiteurs des bêta-sécrétases
CN102952138B (zh) *	2011-08-17	2016-07-06	上海特化医药科技有限公司	一种吡唑并嘧啶酮化合物的盐、多晶型物及其药物组合物、制备方法和应用
JP6043355B2 (ja)	2011-08-31	2016-12-14	ファイザー・インク	ヘキサヒドロピラノ［３，４−ｄ］［１，３］チアジン−２−アミン化合物
ES2585262T3 (es)	2012-05-04	2016-10-04	Pfizer Inc	Compuestos heterocíclicos de hexahidropiran[3,4-d][1,3]tiazin-2-amina sustituidos como inhibidores de PPA, BACE1 y BACE2
CA2882389A1 (fr)	2012-09-20	2014-03-27	Pfizer Inc.	Composes d'hexahydropyrano[3,4-d][1,3]thiazine-2-amine alkyl-substitues
UA110688C2 (uk)	2012-09-21	2016-01-25	Пфайзер Інк.	Біциклічні піридинони
US9637491B2 (en)	2012-10-19	2017-05-02	Origenis Gmbh	Pyrazolo[4,3-D]pyrimidines as kinase inhibitors
CN104755086A (zh)	2012-10-23	2015-07-01	辉瑞公司	四取代的吡唑并[4,3-d]嘧啶化合物用于治疗糖尿病肾病的用途
WO2014091352A1 (fr)	2012-12-11	2014-06-19	Pfizer Inc.	Composés d'hexahydropyrano [3,4-d][1,3]thiazin-2-amine en tant qu'inhibiteurs de bace1
CA2893333C (fr)	2012-12-19	2017-10-24	Pfizer Inc.	Composes hexahydropyrano[3,4-d][1,3]thiazin-2-amine substitues carbocycliques et heterocycliques
WO2014125394A1 (fr)	2013-02-13	2014-08-21	Pfizer Inc.	Composés hexahydropyrano [3,4-d][1,3] thiazin-2-amine substitués par un hétéroaryle
US9233981B1 (en)	2013-02-15	2016-01-12	Pfizer Inc.	Substituted phenyl hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds
AP2015008663A0 (en)	2013-02-19	2015-08-31	Pfizer	Azabenzimidazole compounds as inhibitors of PDE4 isozymes for the treatment of cns and other disorders
CA2925743C (fr)	2013-10-04	2018-03-06	Pfizer Inc.	Nouvelles pyridinones bicycliques utilisees comme modulateurs de gamma-secretase
PE20161364A1 (es)	2014-04-01	2016-12-25	Pfizer	CROMENO Y 1,1a,2,7b-TETRAHIDROCICLOPROPA [C] CROMENO PIRIDOPIRAZINADIONAS NOVEDOSAS
CR20160455A (es)	2014-04-10	2016-12-16	Pfizer	2-AMINO-6-METIL-4,4a,5,6-TETRAHIDROPIRANO[3,4-d][1,3]TIAZIN-8a(8H)-IL-1,3-TIAZOL-4-ILA
EP3172210B1 (fr)	2014-07-24	2020-01-15	Pfizer Inc	Composés de pyrazolopyrimidine
SG11201700243YA (en)	2014-08-06	2017-02-27	Pfizer	Imidazopyridazine compounds
TN2017000342A1 (en)	2015-02-03	2019-01-16	Pfizer	Novel cyclopropabenzofuranyl pyridopyrazinediones
ES2832893T3 (es)	2015-06-17	2021-06-11	Pfizer	Compuestos tricíclicos y su uso como inhibidores de la fosfodiesterasa
JP2018531924A (ja)	2015-09-24	2018-11-01	ファイザー・インク	テトラヒドロピラノ［３，４−ｄ］［１，３］オキサジン誘導体、およびｂａｃｅ阻害剤としてのその使用
EP3353174A1 (fr)	2015-09-24	2018-08-01	Pfizer Inc	N-[2-(3-amino-2,5-diméthyl-1,1-dioxido-5,6-dihydro-2h-1,2,4-thiadiazin-5-yl)-1,3-thiazol-4-yl]amides utiles comme inhibiteurs de bace
WO2017051276A1 (fr)	2015-09-24	2017-03-30	Pfizer Inc.	N-[2-(2-amino-6,6-disubstitués-4,4a,5,6-tétrahydropyrano[3,4-d][1,3]thiazin-8a(8h)-yl)-1,3-thiazol-4-yl]amides
PL3419979T3 (pl)	2016-02-23	2020-06-29	Pfizer Inc.	Związki 6,7-dihydro-5h-pirazolo[5,1-b][1,3]oksazyno-2- karboksyamidowe
HUE054857T2 (hu)	2016-07-01	2021-10-28	Pfizer	5,7-dihidro-pirrolo-piridinszármazékok neurológiai és neurodegeneratív betegségek kezelésére
CN110944998B (zh)	2017-06-22	2022-08-16	辉瑞大药厂	二氢-吡咯并-吡啶衍生物
ES2942837T3 (es)	2018-03-23	2023-06-07	Pfizer	Derivados de azaespiro piperazina
WO2022182658A1 (fr)	2021-02-23	2022-09-01	Hoth Therapeutics, Inc.	Utilisation d'aprépitant pour le traitement de la maladie d'alzheimer
WO2024118524A1 (fr)	2022-11-28	2024-06-06	Cerevel Therapeutics, Llc	Composés d'azaindole et leur utilisation en tant qu'inhibiteurs de phosphodiestérase
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DE10031584A1 (de)	2000-06-29	2002-01-10	Merck Patent Gmbh	5-Aminoalkyl-pyrazolo[4,3-d]pyrimidine
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GB0327319D0 (en)	2003-11-24	2003-12-24	Pfizer Ltd	Novel pharmaceuticals
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GB0327323D0 (en)	2003-11-24	2003-12-31	Pfizer Ltd	Novel pharmaceuticals
DK1742950T3 (da)	2004-04-07	2009-03-16	Pfizer Ltd	Pyrazolo-[4,3-D]-pyrimidiner
JP2008517994A (ja)	2004-10-28	2008-05-29	ファルマシア・アンド・アップジョン・カンパニー・エルエルシー	新規医薬品

2006
- 2006-05-03 CA CA2608018A patent/CA2608018C/fr not_active Expired - Fee Related
- 2006-05-03 DE DE602006019231T patent/DE602006019231D1/de not_active Expired - Lifetime
- 2006-05-03 US US11/913,091 patent/US8227475B2/en not_active Expired - Fee Related
- 2006-05-03 EA EA200702217A patent/EA012577B1/ru not_active IP Right Cessation
- 2006-05-03 AU AU2006245416A patent/AU2006245416B2/en not_active Ceased
- 2006-05-03 EP EP06744689A patent/EP1881985B1/fr not_active Expired - Lifetime
- 2006-05-03 PL PL06744689T patent/PL1881985T3/pl unknown
- 2006-05-03 DK DK06744689.8T patent/DK1881985T3/da active
- 2006-05-03 BR BRPI0609225-0A patent/BRPI0609225A2/pt not_active IP Right Cessation
- 2006-05-03 WO PCT/IB2006/001233 patent/WO2006120552A2/fr not_active Ceased
- 2006-05-03 NZ NZ564187A patent/NZ564187A/en not_active IP Right Cessation
- 2006-05-03 MX MX2007013215A patent/MX2007013215A/es active IP Right Grant
- 2006-05-03 AT AT06744689T patent/ATE493413T1/de active
- 2006-05-03 KR KR1020077026098A patent/KR100939890B1/ko not_active Expired - Fee Related
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- 2006-05-11 JP JP2006132110A patent/JP4271695B2/ja not_active Expired - Fee Related
2007
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- 2007-10-16 IL IL186693A patent/IL186693A/en not_active IP Right Cessation
- 2007-11-09 CR CR9505A patent/CR9505A/es unknown
- 2007-11-09 TN TNP2007000414A patent/TNSN07414A1/fr unknown
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2009
- 2009-01-07 JP JP2009001627A patent/JP4996631B2/ja not_active Expired - Fee Related
2011
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2012
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Also Published As

Publication number	Publication date
AU2006245416A1 (en)	2006-11-16
US8227475B2 (en)	2012-07-24
US20080194591A1 (en)	2008-08-14
EP1881985A2 (fr)	2008-01-30
EA200702217A1 (ru)	2008-04-28
NZ564187A (en)	2010-03-26
JP4271695B2 (ja)	2009-06-03
EA012577B1 (ru)	2009-10-30
PT1881985E (pt)	2011-02-01
US8796287B2 (en)	2014-08-05
MX2007013215A (es)	2007-12-12
ATE493413T1 (de)	2011-01-15
CY1111171T1 (el)	2015-06-11
JP4996631B2 (ja)	2012-08-08
PL1881985T3 (pl)	2011-05-31
US20120214827A1 (en)	2012-08-23
TWI380986B (zh)	2013-01-01
HK1116485A1 (en)	2008-12-24
IL186693A (en)	2012-07-31
AU2006245416B2 (en)	2012-02-23
JP2006316058A (ja)	2006-11-24
US20120208830A1 (en)	2012-08-16
TW200716641A (en)	2007-05-01
WO2006120552A2 (fr)	2006-11-16
CA2608018A1 (fr)	2006-11-16
KR20080004593A (ko)	2008-01-09
WO2006120552A3 (fr)	2007-01-18
CR9505A (es)	2008-01-02
CA2608018C (fr)	2010-07-13
BRPI0609225A2 (pt)	2010-03-09
JP2009137987A (ja)	2009-06-25
NO20075258L (no)	2007-11-15
DK1881985T3 (da)	2011-02-14
EP1881985B1 (fr)	2010-12-29
KR100939890B1 (ko)	2010-01-29
IL186693A0 (en)	2008-02-09
US8796288B2 (en)	2014-08-05
TNSN07414A1 (fr)	2009-03-17
DE602006019231D1 (en)	2011-02-10

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TNSN07414A1 (fr)	2009-03-17	Formes cristallines anhydres de n-[1-(2-ethoxyethyl) -5- (n-ethyl-n-methylamino) -7-(4-methylpyridine -2- yl-amino) -1h-pyrazolo [4,3-d] pyrimidine -3- carbonyl]methanesulfonamide
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DK1863812T3 (da)	2010-10-18	Dipeptidylpeptidase-IV-inhiberende forbindelser, fremgangsmåder til fremstilling af de samme og farmaceutiske sammensætninger indeholdende de samme som aktive midler
WO2007027527A3 (fr)	2007-05-24	Composes d'isoindole-imide et compositions renfermant ceux-ci et procedes d'utilisation de ceux-ci
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PT1379520E (pt)	2006-08-31	Antagonistas (nao-aril)-heterociclicos n-substituidos de nmda/nr2b
TN2011000245A1 (en)	2012-12-17	Organic compounds
WO2004074244A3 (fr)	2004-11-11	Composes de pyrimidine
WO2003095455A3 (fr)	2003-12-24	Composes therapeutiques
MX2009008540A (es)	2009-08-18	Inhibidores de virus de hepatitis c macrociclicos sustituidos con pirimidina.
UA83091C2 (en)	2008-06-10	Pyrido[2,3-d]pyrimidine-2,4-diamines as pde 2 inhibitors
WO2007084424A3 (fr)	2007-10-04	Traitement de l'abus de substances
WO2007146124A3 (fr)	2008-02-14	Inhibiteurs de pde5 substitué
CL2004001085A1 (es)	2005-06-03	Compuestos derivados de quinolil propil piperidina, procedimiento de preparacion; compuesto intermediario; composicion farmaceutica, utiles como agentes microbianos.
WO2006116148A3 (fr)	2008-09-12	Traitement de l'abus de substances toxiques
WO2007059230A3 (fr)	2007-08-02	1h-benzimidazole-4-carboxamides substitues efficaces en tant qu’inhibiteurs de parp
TW200731974A (en)	2007-09-01	Transdermal system for verenicline
WO2007120333A3 (fr)	2008-01-10	Inhibiteurs de kinase tétracycliques
WO2007056625A3 (fr)	2008-09-12	Inhibiteurs de thienopyridine b-raf kinase
WO2008004100A3 (fr)	2011-06-16	Composés thérapeutiques
WO2006088903A3 (fr)	2007-05-10	Composes pyrazole
DK1948661T3 (da)	2009-09-07	Pyrazolo[4,3-D]pyrimidin-5-YL)-derivat anvendt som PDE5-inhibitorer
WO2006124865A3 (fr)	2007-01-11	Biaryles utiles en tant que modulateurs des canaux ioniques
ITTO20030850A1 (it)	2005-04-30	Procedimento per la preparazione di 4-ammino-3,5-dicloro-benzotrifloruro.