NO20075258L - Vannfrie krystallinske former av N-(1-(2-etoksyetyl)-5-(N-etyl-N-metylamino)-7-(4-metylpyndin-2-yl-amino)-1H-pyrazolo(4,3-d)pyrimidin-3-carbonyl)metansulfonamid - Google Patents

Vannfrie krystallinske former av N-(1-(2-etoksyetyl)-5-(N-etyl-N-metylamino)-7-(4-metylpyndin-2-yl-amino)-1H-pyrazolo(4,3-d)pyrimidin-3-carbonyl)metansulfonamid

Info

Publication number: NO20075258L
Authority: NO; Norway
Prior art keywords: methanesulfonamide; methylpyridin; pyrazolo; ethoxyethyl; methylamino
Prior art date: 2005-05-12

Application number

NO20075258A

Other languages

English (en)

Norwegian (no)

Inventor

David Andrew Entwistle

Peter Wallance Marshall

Stefan Colin Taylor

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-05-12

Filing date

2007-10-12

Publication date

2007-11-15

2007-10-12 Application filed by Pfizer filed Critical Pfizer

2007-11-15 Publication of NO20075258L publication Critical patent/NO20075258L/no

Links

-1 2-ethoxyethyl Chemical group 0.000 title 4
ZUHZNKJIJDAJFD-UHFFFAOYSA-N 1-(2-ethoxyethyl)-5-[ethyl(methyl)amino]-7-[(4-methylpyridin-2-yl)amino]-n-methylsulfonylpyrazolo[4,3-d]pyrimidine-3-carboxamide Chemical compound C=12N(CCOCC)N=C(C(=O)NS(C)(=O)=O)C2=NC(N(C)CC)=NC=1NC1=CC(C)=CC=N1 ZUHZNKJIJDAJFD-UHFFFAOYSA-N 0.000 abstract 2
102000011016 Type 5 Cyclic Nucleotide Phosphodiesterases Human genes 0.000 abstract 1
108010037581 Type 5 Cyclic Nucleotide Phosphodiesterases Proteins 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000001404 mediated effect Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A—HUMAN NECESSITIES
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- A61P11/00—Drugs for disorders of the respiratory system
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

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Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
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Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Diabetes (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Endocrinology (AREA)
Obesity (AREA)
Reproductive Health (AREA)
Hematology (AREA)
Pulmonology (AREA)
Urology & Nephrology (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Psychiatry (AREA)
Orthopedic Medicine & Surgery (AREA)
Ophthalmology & Optometry (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
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Psychology (AREA)
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NO20075258A 2005-05-12 2007-10-12 Vannfrie krystallinske former av N-(1-(2-etoksyetyl)-5-(N-etyl-N-metylamino)-7-(4-metylpyndin-2-yl-amino)-1H-pyrazolo(4,3-d)pyrimidin-3-carbonyl)metansulfonamid NO20075258L (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US68044505P	2005-05-12	2005-05-12
US68171105P	2005-05-17	2005-05-17
PCT/IB2006/001233 WO2006120552A2 (fr)	2005-05-12	2006-05-03	Formes cristallines anhydres de n-[1-(2-ethoxyethyl)-5-(n-ethyl-n-methylamino)-7-(4-methylpyridin-2-yl-amino)-1h-pyrazolo[4,3-d]pyrimidine-3-carbonyl]methanesulfonamide

Publications (1)

Publication Number	Publication Date
NO20075258L true NO20075258L (no)	2007-11-15

Family

ID=37106941

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20075258A NO20075258L (no)	2005-05-12	2007-10-12	Vannfrie krystallinske former av N-(1-(2-etoksyetyl)-5-(N-etyl-N-metylamino)-7-(4-metylpyndin-2-yl-amino)-1H-pyrazolo(4,3-d)pyrimidin-3-carbonyl)metansulfonamid

Country Status (23)

Country	Link
US (3)	US8227475B2 (fr)
EP (1)	EP1881985B1 (fr)
JP (2)	JP4271695B2 (fr)
KR (1)	KR100939890B1 (fr)
AT (1)	ATE493413T1 (fr)
AU (1)	AU2006245416B2 (fr)
BR (1)	BRPI0609225A2 (fr)
CA (1)	CA2608018C (fr)
CR (1)	CR9505A (fr)
CY (1)	CY1111171T1 (fr)
DE (1)	DE602006019231D1 (fr)
DK (1)	DK1881985T3 (fr)
EA (1)	EA012577B1 (fr)
IL (1)	IL186693A (fr)
MA (1)	MA29447B1 (fr)
MX (1)	MX2007013215A (fr)
NO (1)	NO20075258L (fr)
NZ (1)	NZ564187A (fr)
PL (1)	PL1881985T3 (fr)
PT (1)	PT1881985E (fr)
TN (1)	TNSN07414A1 (fr)
TW (1)	TWI380986B (fr)
WO (1)	WO2006120552A2 (fr)

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ES2832893T3 (es)	2015-06-17	2021-06-11	Pfizer	Compuestos tricíclicos y su uso como inhibidores de la fosfodiesterasa
JP2018531924A (ja)	2015-09-24	2018-11-01	ファイザー・インク	テトラヒドロピラノ［３，４−ｄ］［１，３］オキサジン誘導体、およびｂａｃｅ阻害剤としてのその使用
EP3353174A1 (fr)	2015-09-24	2018-08-01	Pfizer Inc	N-[2-(3-amino-2,5-diméthyl-1,1-dioxido-5,6-dihydro-2h-1,2,4-thiadiazin-5-yl)-1,3-thiazol-4-yl]amides utiles comme inhibiteurs de bace
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GB0327323D0 (en)	2003-11-24	2003-12-31	Pfizer Ltd	Novel pharmaceuticals
DK1742950T3 (da)	2004-04-07	2009-03-16	Pfizer Ltd	Pyrazolo-[4,3-D]-pyrimidiner
JP2008517994A (ja)	2004-10-28	2008-05-29	ファルマシア・アンド・アップジョン・カンパニー・エルエルシー	新規医薬品

2006
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Also Published As

Publication number	Publication date
AU2006245416A1 (en)	2006-11-16
US8227475B2 (en)	2012-07-24
US20080194591A1 (en)	2008-08-14
EP1881985A2 (fr)	2008-01-30
MA29447B1 (fr)	2008-05-02
EA200702217A1 (ru)	2008-04-28
NZ564187A (en)	2010-03-26
JP4271695B2 (ja)	2009-06-03
EA012577B1 (ru)	2009-10-30
PT1881985E (pt)	2011-02-01
US8796287B2 (en)	2014-08-05
MX2007013215A (es)	2007-12-12
ATE493413T1 (de)	2011-01-15
CY1111171T1 (el)	2015-06-11
JP4996631B2 (ja)	2012-08-08
PL1881985T3 (pl)	2011-05-31
US20120214827A1 (en)	2012-08-23
TWI380986B (zh)	2013-01-01
HK1116485A1 (en)	2008-12-24
IL186693A (en)	2012-07-31
AU2006245416B2 (en)	2012-02-23
JP2006316058A (ja)	2006-11-24
US20120208830A1 (en)	2012-08-16
TW200716641A (en)	2007-05-01
WO2006120552A2 (fr)	2006-11-16
CA2608018A1 (fr)	2006-11-16
KR20080004593A (ko)	2008-01-09
WO2006120552A3 (fr)	2007-01-18
CR9505A (es)	2008-01-02
CA2608018C (fr)	2010-07-13
BRPI0609225A2 (pt)	2010-03-09
JP2009137987A (ja)	2009-06-25
DK1881985T3 (da)	2011-02-14
EP1881985B1 (fr)	2010-12-29
KR100939890B1 (ko)	2010-01-29
IL186693A0 (en)	2008-02-09
US8796288B2 (en)	2014-08-05
TNSN07414A1 (fr)	2009-03-17
DE602006019231D1 (en)	2011-02-10

Legal Events

Date	Code	Title	Description
2009-12-21	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
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ATE430747T1 (de)	2009-05-15	2-pyrimidinyl-pyrazolopyridin-erbb- kinaseinhibitoren
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WO2007120333A3 (fr)	2008-01-10	Inhibiteurs de kinase tétracycliques
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