MA32687B1 - Emulsions à libération modifiée destinées à une application sur la peau ou la muqueuse vaginale - Google Patents

Emulsions à libération modifiée destinées à une application sur la peau ou la muqueuse vaginale

Info

Publication number
MA32687B1
MA32687B1 MA33736A MA33736A MA32687B1 MA 32687 B1 MA32687 B1 MA 32687B1 MA 33736 A MA33736 A MA 33736A MA 33736 A MA33736 A MA 33736A MA 32687 B1 MA32687 B1 MA 32687B1
Authority
MA
Morocco
Prior art keywords
modified release
skin
application
vaginal mucosa
emulsions
Prior art date
Application number
MA33736A
Other languages
Arabic (ar)
English (en)
Inventor
Emanuela Mura
Federico Mailland
Daniela Ceriani
Original Assignee
Polichem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40340663&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA32687(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Polichem Sa filed Critical Polichem Sa
Publication of MA32687B1 publication Critical patent/MA32687B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/345—Nitrofurans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Colloid Chemistry (AREA)

Abstract

La présente invention concerne des émulsions huile dans l'eau à libération modifiée qui délivrent des médicaments à un tissu cible. Les émulsions selon la présente invention contiennent le principe actif lipophile complètement dissous dans la phase interne hydrophobe stabilisée par un surfactant polymère. La présence de ce polymère autour des gouttelettes hydrophobes évite la migration du principe actif dans la phase hydrophile externe et, en conséquence, sa recristallisation.
MA33736A 2008-10-08 2011-04-01 Emulsions à libération modifiée destinées à une application sur la peau ou la muqueuse vaginale MA32687B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08166058A EP2174650A1 (fr) 2008-10-08 2008-10-08 Émulsions à libération modifiée pour une application sur la peau ou la muqueuse vaginale
PCT/EP2009/062190 WO2010040632A1 (fr) 2008-10-08 2009-09-21 Emulsions à libération modifiée destinées à une application sur la peau ou la muqueuse vaginale

Publications (1)

Publication Number Publication Date
MA32687B1 true MA32687B1 (fr) 2011-10-02

Family

ID=40340663

Family Applications (1)

Application Number Title Priority Date Filing Date
MA33736A MA32687B1 (fr) 2008-10-08 2011-04-01 Emulsions à libération modifiée destinées à une application sur la peau ou la muqueuse vaginale

Country Status (19)

Country Link
US (1) US20110195944A1 (fr)
EP (2) EP2174650A1 (fr)
JP (1) JP2012505171A (fr)
KR (1) KR20110067115A (fr)
CN (1) CN102170862A (fr)
AR (1) AR073801A1 (fr)
AU (1) AU2009301275A1 (fr)
BR (1) BRPI0920565A2 (fr)
CA (1) CA2737255A1 (fr)
CL (1) CL2011000767A1 (fr)
CO (1) CO6361898A2 (fr)
EA (1) EA201170555A1 (fr)
IL (1) IL211681A0 (fr)
MA (1) MA32687B1 (fr)
MX (1) MX2011003696A (fr)
NZ (1) NZ591919A (fr)
PE (1) PE20110449A1 (fr)
WO (1) WO2010040632A1 (fr)
ZA (1) ZA201101818B (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012103421A1 (fr) * 2011-01-27 2012-08-02 Novartis Ag Nanoémulsions d'adjuvant à inhibiteurs de cristallisation
CA2829241A1 (fr) 2011-04-01 2012-10-04 University Of Florida Research Foundation, Inc. Formulations thermosensibles, mucoadhesives ou dermoadhesives et ameliorant la penetration pour l'administration topique de produits therapeutiques
DE102011076869A1 (de) * 2011-06-01 2012-12-06 Beiersdorf Ag Emulsionszubereitungen mit verbesserten rheologischen Eigenschaften
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
RS62297B1 (sr) 2011-11-23 2021-09-30 Therapeuticsmd Inc Prirodne kombinovane hormonske supstitucione formulacije i terapije
CN104105472A (zh) 2011-12-20 2014-10-15 维奥姆生物科学有限公司 用于治疗真菌感染的局部油组合物
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
EA201591954A1 (ru) * 2013-04-12 2016-04-29 Вайом Байосайнсиз Пвт. Лтд. Композиция и состав противомикробных средств, способы их получения и способы лечения микробных инфекций
WO2015138668A1 (fr) * 2014-03-12 2015-09-17 Warner Chilcott Company, Llc Crème d'estradiol à faible dose
RU2016143081A (ru) 2014-05-22 2018-06-26 Терапьютиксмд, Инк. Натуральные комбинированные гормонозаместительные составы и терапии
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
US9931349B2 (en) 2016-04-01 2018-04-03 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
JP7219712B2 (ja) * 2016-10-13 2023-02-08 キャタレント・ユーケー・スウィンドン・ザイディス・リミテッド 膣送達のための凍結乾燥医薬組成物
MX2019015927A (es) * 2017-06-22 2020-08-06 Viramal Ltd Composiciones para administración de fármacos y métodos de uso de las mismas.
WO2019213473A1 (fr) 2018-05-04 2019-11-07 The Procter & Gamble Company Compositions et méthodes de traitement de la sécheresse vaginale
EP3870150A1 (fr) 2018-10-26 2021-09-01 Viramal Limited Composition de gel mucoadhésif
ES2948955T3 (es) 2018-11-30 2023-09-22 Viramal Ltd Un método de preparación de un agente gelificante, el agente gelificante obtenido de este modo y el uso de dicho agente gelificante

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7169819B2 (en) * 2000-12-05 2007-01-30 Childrens Hospital Los Angeles Pharmaceutical compositions of fenretinide having increased bioavailability and methods of using the same
AU2003218507A1 (en) * 2002-04-04 2003-10-20 Medicis Pharmaceutical Corporation Methods for treating rosacea with pyridones
US20060233721A1 (en) * 2002-10-25 2006-10-19 Foamix Ltd. Foam containing unique oil globules
US20060018937A1 (en) * 2002-10-25 2006-01-26 Foamix Ltd. Steroid kit and foamable composition and uses thereof
US20040087564A1 (en) * 2002-10-31 2004-05-06 Wright D. Craig Delivery composition and method
WO2007099396A2 (fr) * 2005-06-07 2007-09-07 Foamix Ltd. Kit et composition antibiotiques et leurs utilisations
US20070071705A1 (en) * 2005-09-29 2007-03-29 De Oliveira Monica A M Topical anti-microbial compositions
US20080075745A1 (en) * 2006-09-21 2008-03-27 Glenmark Pharmaceuticals Limited Topical pharmaceutical compositions containing ciclopirox or a pharmaceutically acceptable salt thereof

Also Published As

Publication number Publication date
NZ591919A (en) 2012-09-28
EP2174650A1 (fr) 2010-04-14
CO6361898A2 (es) 2012-01-20
BRPI0920565A2 (pt) 2015-12-29
AR073801A1 (es) 2010-12-01
AU2009301275A2 (en) 2011-04-28
AU2009301275A1 (en) 2010-04-15
EP2331065A1 (fr) 2011-06-15
KR20110067115A (ko) 2011-06-21
MX2011003696A (es) 2011-06-20
PE20110449A1 (es) 2011-07-07
CA2737255A1 (fr) 2010-04-15
US20110195944A1 (en) 2011-08-11
WO2010040632A1 (fr) 2010-04-15
CN102170862A (zh) 2011-08-31
JP2012505171A (ja) 2012-03-01
CL2011000767A1 (es) 2011-06-17
IL211681A0 (en) 2011-06-30
EA201170555A1 (ru) 2011-12-30
ZA201101818B (en) 2012-05-30

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