MA33119B1 - Derives de benzofuranyle utilises comme inhibiteurs de la glucokinase - Google Patents
Derives de benzofuranyle utilises comme inhibiteurs de la glucokinaseInfo
- Publication number
- MA33119B1 MA33119B1 MA34164A MA34164A MA33119B1 MA 33119 B1 MA33119 B1 MA 33119B1 MA 34164 A MA34164 A MA 34164A MA 34164 A MA34164 A MA 34164A MA 33119 B1 MA33119 B1 MA 33119B1
- Authority
- MA
- Morocco
- Prior art keywords
- glucokinase
- glucokinase inhibitors
- benzofuranyl derivatives
- benzofuranyl
- derivatives
- Prior art date
Links
- 102000030595 Glucokinase Human genes 0.000 title abstract 3
- 108010021582 Glucokinase Proteins 0.000 title abstract 3
- -1 BENZOFURANYL Chemical class 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 239000012190 activator Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La présente invention concerne des composés de formule (I) qui agissent comme activateurs de la glucokinase. L'invention concerne également des compositions pharmaceutiques comprenant ceux-ci ; et des procédés de traitement de maladies, de troubles, ou d'états pathologiques induits par la glucokinase.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15909909P | 2009-03-11 | 2009-03-11 | |
| PCT/IB2010/050943 WO2010103437A1 (fr) | 2009-03-11 | 2010-03-04 | Dérivés de benzofuranyle utilisés comme inhibiteurs de la glucokinase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA33119B1 true MA33119B1 (fr) | 2012-03-01 |
Family
ID=42124287
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA34164A MA33119B1 (fr) | 2009-03-11 | 2010-03-04 | Derives de benzofuranyle utilises comme inhibiteurs de la glucokinase |
Country Status (37)
| Country | Link |
|---|---|
| US (2) | US8455496B2 (fr) |
| EP (2) | EP2604604A1 (fr) |
| JP (1) | JP5086480B2 (fr) |
| KR (1) | KR101295937B1 (fr) |
| CN (1) | CN102388038B (fr) |
| AP (1) | AP3179A (fr) |
| AR (1) | AR075729A1 (fr) |
| AU (1) | AU2010222589B2 (fr) |
| BR (1) | BRPI1013246B1 (fr) |
| CA (1) | CA2754681C (fr) |
| CL (1) | CL2011002185A1 (fr) |
| CO (1) | CO6430427A2 (fr) |
| CR (1) | CR20110467A (fr) |
| CU (1) | CU24036B1 (fr) |
| DK (1) | DK2406253T3 (fr) |
| DO (1) | DOP2011000279A (fr) |
| EA (1) | EA018894B1 (fr) |
| EC (1) | ECSP11011306A (fr) |
| ES (1) | ES2427279T3 (fr) |
| GE (1) | GEP20156239B (fr) |
| HR (1) | HRP20130661T1 (fr) |
| IL (1) | IL214942A (fr) |
| MA (1) | MA33119B1 (fr) |
| MY (1) | MY151246A (fr) |
| NI (1) | NI201100166A (fr) |
| NZ (1) | NZ595024A (fr) |
| PE (1) | PE20120668A1 (fr) |
| PL (1) | PL2406253T3 (fr) |
| PT (1) | PT2406253E (fr) |
| RS (1) | RS52903B (fr) |
| SI (1) | SI2406253T1 (fr) |
| TN (1) | TN2011000454A1 (fr) |
| TW (1) | TWI383981B (fr) |
| UA (1) | UA99882C2 (fr) |
| UY (1) | UY32480A (fr) |
| WO (1) | WO2010103437A1 (fr) |
| ZA (1) | ZA201106632B (fr) |
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| EA022375B1 (ru) | 2011-04-22 | 2015-12-30 | Пфайзер Инк. | ПРОИЗВОДНЫЕ ПИРАЗОЛОСПИРОКЕТОНОВ ДЛЯ ПРИМЕНЕНИЯ В КАЧЕСТВЕ ИНГИБИТОРОВ АЦЕТИЛ-КоА-КАРБОКСИЛАЗ |
| JP2014520879A (ja) | 2011-07-15 | 2014-08-25 | ファイザー・インク | Ｇｐｒ１１９調節因子 |
| RU2013157388A (ru) | 2011-07-22 | 2015-08-27 | Пфайзер Инк. | Хинолинильные модуляторы глюкагонового рецептора |
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