MA34314B1 - Préparation de paracétamol injectable stable, prête à l'emploi - Google Patents
Préparation de paracétamol injectable stable, prête à l'emploiInfo
- Publication number
- MA34314B1 MA34314B1 MA35461A MA35461A MA34314B1 MA 34314 B1 MA34314 B1 MA 34314B1 MA 35461 A MA35461 A MA 35461A MA 35461 A MA35461 A MA 35461A MA 34314 B1 MA34314 B1 MA 34314B1
- Authority
- MA
- Morocco
- Prior art keywords
- paracetamol
- ready
- preparation
- group
- injectable stable
- Prior art date
Links
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 title abstract 3
- 229960005489 paracetamol Drugs 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 230000000087 stabilizing effect Effects 0.000 abstract 2
- 229920000858 Cyclodextrin Polymers 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 229940097362 cyclodextrins Drugs 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- 238000001802 infusion Methods 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 150000003544 thiamines Chemical class 0.000 abstract 1
- 150000003573 thiols Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Cette invention concerne une solution aqueuse de paracétamol administrable par perfusion intraveineuse qui comprend pour le paracétamol en solution au moins un composé de stabilisation-dissolution pris dans le groupe composé de cyclodextrines, au moins un composé stabilisateur portant au moins un groupe fonctionnel thiol et au moins un composé stabilisateur pris dans le groupe composé de sels de thiamine.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10005258A EP2389923B1 (fr) | 2010-05-19 | 2010-05-19 | Formule de paracétamol injectable, stable et prête à utiliser |
| PCT/EP2011/002482 WO2011144335A1 (fr) | 2010-05-19 | 2011-05-18 | Préparation de paracétamol injectable stable, prête à l'emploi |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA34314B1 true MA34314B1 (fr) | 2013-06-01 |
Family
ID=42338244
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA35461A MA34314B1 (fr) | 2010-05-19 | 2011-05-18 | Préparation de paracétamol injectable stable, prête à l'emploi |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US8877817B2 (fr) |
| EP (1) | EP2389923B1 (fr) |
| CN (1) | CN102985069B (fr) |
| AP (1) | AP3151A (fr) |
| BR (1) | BR112012029212A2 (fr) |
| CA (1) | CA2799666C (fr) |
| CY (1) | CY1113999T1 (fr) |
| DK (1) | DK2389923T3 (fr) |
| ES (1) | ES2403121T3 (fr) |
| HR (1) | HRP20130184T1 (fr) |
| MA (1) | MA34314B1 (fr) |
| MY (1) | MY160458A (fr) |
| PL (1) | PL2389923T3 (fr) |
| PT (1) | PT2389923E (fr) |
| RU (1) | RU2519764C1 (fr) |
| SI (1) | SI2389923T1 (fr) |
| SM (1) | SMT201300038B (fr) |
| TN (1) | TN2012000516A1 (fr) |
| UA (1) | UA104381C2 (fr) |
| WO (1) | WO2011144335A1 (fr) |
| ZA (1) | ZA201208605B (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA201300398B (en) * | 2012-11-27 | 2013-09-25 | Genfarma Laboratories S L | Injectable liquid formulation of the combination of tramadol and paracetamol |
| WO2016008546A1 (fr) * | 2014-07-18 | 2016-01-21 | Everbright Pharmaceuticals S.A.R.L. | Formulation aqueuse comprenant du paracétamol et de l'ibuprofène |
| CN105797166A (zh) * | 2016-03-30 | 2016-07-27 | 吉林长白山药业集团股份有限公司 | 用羟丙基环糊精包合对乙酰氨基酚制成液体制剂的方法 |
| WO2018192664A1 (fr) | 2017-04-20 | 2018-10-25 | Hyloris Developments Sa | Procédé de préparation d'une composition à faible teneur en oxygène dissous, comprenant de l'acétaminophène, et éventuellement un ou plusieurs ains, et une composition obtenue à partir de celui-ci |
| WO2019180072A1 (fr) | 2018-03-22 | 2019-09-26 | Bayer Pharma Aktiengesellschaft | Composition pharmaceutique parentérale consistant en du bialanate de néladénoson |
| US20230165928A1 (en) * | 2020-04-30 | 2023-06-01 | Blue Sky Innovation, Llc | Compositions and methods comprising stable reduced glutathione |
| GR1010637B (el) * | 2023-01-13 | 2024-02-15 | Ιουλια Κλεωνος Τσετη | Σταθερο υδατικο διαλυμα παρακεταμολης για χρηση σε ενδοφλεβια εγχυση |
| IL324832A (en) | 2023-06-02 | 2026-01-01 | Ioulia Tseti | Pharmaceutical composition comprising ibuprofen |
| GR1010809B (el) * | 2023-09-13 | 2024-10-25 | Ιουλια Τσετη | Υδατικο διαλυμα ιβουπροφαινης παρακεταμολης για χρηση σε ενδοφλεβια χορηγηση |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH648371A5 (de) | 1982-01-29 | 1985-03-15 | Fischer Ag Georg | Anschlusseinrichtung fuer armaturen. |
| US4727064A (en) | 1984-04-25 | 1988-02-23 | The United States Of America As Represented By The Department Of Health And Human Services | Pharmaceutical preparations containing cyclodextrin derivatives |
| FR2751875B1 (fr) | 1996-08-05 | 1998-12-24 | Scr Newpharm | Nouvelles formulations liquides stables a base de paracetamol et leur mode de preparation |
| JP2001233787A (ja) * | 2000-02-04 | 2001-08-28 | Patents Exploitation Co Bv | 小・中サイズのペプチド含有薬学的組成物 |
| US20040045546A1 (en) * | 2002-09-05 | 2004-03-11 | Peirce Management, Llc | Pharmaceutical delivery system for oral inhalation through nebulization consisting of inert substrate impregnated with substance (S) to be solubilized or suspended prior to use |
| FR2851164B1 (fr) * | 2003-02-14 | 2005-04-22 | Xuan Tho Nguyen | Formulation liquide injectable de paracetamol |
| JP5909750B2 (ja) * | 2007-11-13 | 2016-04-27 | マリンクロット アイピー | 低用量静脈内アセトアミノフェン |
| WO2009098716A2 (fr) * | 2008-01-17 | 2009-08-13 | Aptuit Laurus Private Limited | Compositions pharmaceutiques aqueuses stables |
| US20090246276A1 (en) * | 2008-01-28 | 2009-10-01 | Graham Jackson | Pharmaceutical Compositions |
| NZ596979A (en) * | 2008-02-29 | 2012-06-29 | Meiji Co Ltd | Anti-allergic agent comprising a fermentation product of a propionic acid bacterium |
-
2010
- 2010-05-19 DK DK10005258.8T patent/DK2389923T3/da active
- 2010-05-19 ES ES10005258T patent/ES2403121T3/es active Active
- 2010-05-19 PT PT100052588T patent/PT2389923E/pt unknown
- 2010-05-19 PL PL10005258T patent/PL2389923T3/pl unknown
- 2010-05-19 EP EP10005258A patent/EP2389923B1/fr active Active
- 2010-05-19 SI SI201030168T patent/SI2389923T1/sl unknown
-
2011
- 2011-05-18 RU RU2012151433/15A patent/RU2519764C1/ru active
- 2011-05-18 MY MYPI2012004801A patent/MY160458A/en unknown
- 2011-05-18 BR BR112012029212-9A patent/BR112012029212A2/pt not_active Application Discontinuation
- 2011-05-18 AP AP2012006597A patent/AP3151A/xx active
- 2011-05-18 WO PCT/EP2011/002482 patent/WO2011144335A1/fr not_active Ceased
- 2011-05-18 MA MA35461A patent/MA34314B1/fr unknown
- 2011-05-18 CA CA2799666A patent/CA2799666C/fr not_active Expired - Fee Related
- 2011-05-18 CN CN201180024241.4A patent/CN102985069B/zh not_active Expired - Fee Related
- 2011-05-18 UA UAA201214331A patent/UA104381C2/uk unknown
- 2011-05-18 US US13/695,785 patent/US8877817B2/en active Active
-
2012
- 2012-10-29 TN TNP2012000516A patent/TN2012000516A1/en unknown
- 2012-11-15 ZA ZA2012/08605A patent/ZA201208605B/en unknown
-
2013
- 2013-03-04 HR HRP20130184AT patent/HRP20130184T1/hr unknown
- 2013-03-22 CY CY20131100241T patent/CY1113999T1/el unknown
- 2013-04-03 SM SM201300038T patent/SMT201300038B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SMT201300038B (it) | 2013-07-09 |
| WO2011144335A8 (fr) | 2012-12-06 |
| US8877817B2 (en) | 2014-11-04 |
| BR112012029212A2 (pt) | 2020-09-29 |
| ZA201208605B (en) | 2013-09-25 |
| WO2011144335A1 (fr) | 2011-11-24 |
| EP2389923B1 (fr) | 2013-01-30 |
| PT2389923E (pt) | 2013-03-28 |
| AP2012006597A0 (en) | 2012-12-31 |
| EP2389923A1 (fr) | 2011-11-30 |
| CY1113999T1 (el) | 2016-07-27 |
| CN102985069B (zh) | 2014-11-26 |
| PL2389923T3 (pl) | 2013-06-28 |
| HRP20130184T1 (hr) | 2013-05-31 |
| CN102985069A (zh) | 2013-03-20 |
| TN2012000516A1 (en) | 2014-04-01 |
| CA2799666C (fr) | 2016-02-16 |
| RU2519764C1 (ru) | 2014-06-20 |
| AP3151A (en) | 2015-03-31 |
| ES2403121T3 (es) | 2013-05-14 |
| DK2389923T3 (da) | 2013-03-18 |
| UA104381C2 (uk) | 2014-01-27 |
| US20130210922A1 (en) | 2013-08-15 |
| MY160458A (en) | 2017-03-15 |
| CA2799666A1 (fr) | 2011-11-24 |
| HK1182315A1 (en) | 2013-11-29 |
| SI2389923T1 (sl) | 2013-06-28 |
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