MA40761A - Utilisation de panels de gènes mutants du fgfr dans l'identification de patients atteints de cancer qui seront sensibles à un traitement avec un inhibiteur du fgfr - Google Patents

Utilisation de panels de gènes mutants du fgfr dans l'identification de patients atteints de cancer qui seront sensibles à un traitement avec un inhibiteur du fgfr

Info

Publication number
MA40761A
MA40761A MA040761A MA40761A MA40761A MA 40761 A MA40761 A MA 40761A MA 040761 A MA040761 A MA 040761A MA 40761 A MA40761 A MA 40761A MA 40761 A MA40761 A MA 40761A
Authority
MA
Morocco
Prior art keywords
fgfr
cancer
sensitive
treatment
mutant gene
Prior art date
Application number
MA040761A
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English (en)
Other versions
MA40761B1 (fr
Inventor
Jayaprakash Karkera
Suso Jesus Platero
Original Assignee
Janssen Pharmaceutica Nv
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54337343&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA40761(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of MA40761A publication Critical patent/MA40761A/fr
Publication of MA40761B1 publication Critical patent/MA40761B1/fr

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2531/00Reactions of nucleic acids characterised by
    • C12Q2531/10Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
    • C12Q2531/113PCR
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
MA40761A 2014-09-26 2015-09-18 Utilisation de panels de gènes mutants du fgfr dans l'identification de patients atteints de cancer qui seront sensibles à un traitement avec un inhibiteur du fgfr MA40761B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462056159P 2014-09-26 2014-09-26
PCT/US2015/050996 WO2016048833A2 (fr) 2014-09-26 2015-09-18 Utilisation de panels de gènes mutants du fgfr dans l'identification de patients atteints de cancer qui seront sensibles à un traitement avec un inhibiteur du fgfr

Publications (2)

Publication Number Publication Date
MA40761A true MA40761A (fr) 2017-08-01
MA40761B1 MA40761B1 (fr) 2022-04-29

Family

ID=54337343

Family Applications (1)

Application Number Title Priority Date Filing Date
MA40761A MA40761B1 (fr) 2014-09-26 2015-09-18 Utilisation de panels de gènes mutants du fgfr dans l'identification de patients atteints de cancer qui seront sensibles à un traitement avec un inhibiteur du fgfr

Country Status (38)

Country Link
US (3) US20160090633A1 (fr)
EP (2) EP4063516A1 (fr)
JP (4) JP6766037B2 (fr)
KR (3) KR102839867B1 (fr)
CN (1) CN107002141B (fr)
AR (1) AR102345A1 (fr)
AU (3) AU2015321626B2 (fr)
CA (1) CA2962075C (fr)
CO (1) CO2017003528A2 (fr)
CR (1) CR20170104A (fr)
CY (1) CY1125190T1 (fr)
DK (1) DK3198033T3 (fr)
EA (1) EA037920B1 (fr)
EC (1) ECSP17025787A (fr)
ES (1) ES2912567T3 (fr)
GT (1) GT201700059A (fr)
HR (1) HRP20220496T1 (fr)
HU (1) HUE058219T2 (fr)
IL (3) IL324511A (fr)
JO (1) JO3681B1 (fr)
LT (1) LT3198033T (fr)
MA (1) MA40761B1 (fr)
MX (2) MX392774B (fr)
MY (1) MY194567A (fr)
NI (1) NI201700035A (fr)
PH (1) PH12017500556A1 (fr)
PL (1) PL3198033T3 (fr)
PT (1) PT3198033T (fr)
RS (1) RS63178B1 (fr)
SG (1) SG11201702381QA (fr)
SI (1) SI3198033T1 (fr)
SM (1) SMT202200177T1 (fr)
SV (1) SV2017005415A (fr)
TW (1) TWI706136B (fr)
UA (1) UA122564C2 (fr)
UY (1) UY36325A (fr)
WO (1) WO2016048833A2 (fr)
ZA (1) ZA201702899B (fr)

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Publication number Publication date
MY194567A (en) 2022-12-02
US20190078166A1 (en) 2019-03-14
JO3681B1 (ar) 2020-08-27
CA2962075C (fr) 2025-09-09
WO2016048833A3 (fr) 2016-05-19
KR102470456B1 (ko) 2022-11-23
DK3198033T3 (da) 2022-04-11
JP7051920B2 (ja) 2022-04-11
IL291633A (en) 2022-05-01
AU2025201448A1 (en) 2025-03-20
KR102839867B1 (ko) 2025-07-28
SG11201702381QA (en) 2017-04-27
EA037920B1 (ru) 2021-06-07
CY1125190T1 (el) 2024-12-13
GT201700059A (es) 2019-08-21
KR20250119657A (ko) 2025-08-07
CO2017003528A2 (es) 2017-07-11
UY36325A (es) 2016-04-01
CN107002141B (zh) 2021-11-02
KR20220162823A (ko) 2022-12-08
CN113957146A (zh) 2022-01-21
AU2015321626B2 (en) 2021-12-16
UA122564C2 (uk) 2020-12-10
JP7558216B2 (ja) 2024-09-30
ECSP17025787A (es) 2018-07-31
CN107002141A (zh) 2017-08-01
JP2024112991A (ja) 2024-08-21
IL251264A0 (en) 2017-05-29
JP2020124192A (ja) 2020-08-20
SI3198033T1 (sl) 2022-06-30
JP2017529090A (ja) 2017-10-05
EP4063516A1 (fr) 2022-09-28
WO2016048833A2 (fr) 2016-03-31
HRP20220496T1 (hr) 2022-05-27
MA40761B1 (fr) 2022-04-29
ZA201702899B (en) 2019-06-26
MX2022006536A (es) 2022-07-11
EP3198033B1 (fr) 2022-02-16
LT3198033T (lt) 2022-05-10
US12037644B2 (en) 2024-07-16
US20160090633A1 (en) 2016-03-31
PT3198033T (pt) 2022-05-25
TW201619609A (zh) 2016-06-01
NZ730886A (en) 2024-08-30
MX2017003954A (es) 2017-12-14
AR102345A1 (es) 2017-02-22
NI201700035A (es) 2017-06-22
IL251264B (en) 2022-04-01
MX392774B (es) 2025-03-24
AU2021277633A1 (en) 2021-12-23
SV2017005415A (es) 2017-07-03
IL291633B1 (en) 2025-12-01
AU2021277633B2 (en) 2024-11-28
HUE058219T2 (hu) 2022-07-28
EA201790716A1 (ru) 2017-10-31
ES2912567T3 (es) 2022-05-26
JP6766037B2 (ja) 2020-10-07
SMT202200177T1 (it) 2022-05-12
JP2022109910A (ja) 2022-07-28
KR20170062495A (ko) 2017-06-07
US20240309463A1 (en) 2024-09-19
PH12017500556A1 (en) 2017-08-30
TWI706136B (zh) 2020-10-01
PL3198033T3 (pl) 2022-08-29
BR112017006088A2 (pt) 2017-12-19
IL324511A (en) 2026-01-01
CR20170104A (es) 2017-05-31
RS63178B1 (sr) 2022-06-30
EP3198033A2 (fr) 2017-08-02
CA2962075A1 (fr) 2016-03-31
AU2015321626A1 (en) 2017-04-06

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