MA43417A - Agonistes améliorés du récepteur de l'apéline (apj) et leurs utilisations - Google Patents
Agonistes améliorés du récepteur de l'apéline (apj) et leurs utilisationsInfo
- Publication number
- MA43417A MA43417A MA043417A MA43417A MA43417A MA 43417 A MA43417 A MA 43417A MA 043417 A MA043417 A MA 043417A MA 43417 A MA43417 A MA 43417A MA 43417 A MA43417 A MA 43417A
- Authority
- MA
- Morocco
- Prior art keywords
- apeline
- apj
- agonists
- receptor
- enhanced
- Prior art date
Links
- 239000000556 agonist Substances 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
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- A61K31/4196—1,2,4-Triazoles
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- A61K31/42—Oxazoles
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
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- Child & Adolescent Psychology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
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| US201562265168P | 2015-12-09 | 2015-12-09 |
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| EP (1) | EP3386976A1 (fr) |
| JP (2) | JP2019501899A (fr) |
| KR (1) | KR20180090852A (fr) |
| CN (1) | CN108602806B (fr) |
| AU (1) | AU2016366310C1 (fr) |
| BR (1) | BR112018011784A2 (fr) |
| CO (1) | CO2018005871A2 (fr) |
| HK (1) | HK1255452A1 (fr) |
| IL (1) | IL259634A (fr) |
| MA (1) | MA43417A (fr) |
| MX (2) | MX391898B (fr) |
| PE (1) | PE20190258A1 (fr) |
| RU (2) | RU2766148C1 (fr) |
| WO (1) | WO2017100558A1 (fr) |
| ZA (1) | ZA201803301B (fr) |
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| ES3032633T3 (en) | 2016-10-12 | 2025-07-22 | Res Triangle Inst | Heterocyclic apelin receptor (apj) agonists and uses thereof |
| US10906890B2 (en) | 2016-11-16 | 2021-02-02 | Amgen Inc. | Triazole phenyl compounds as agonists of the APJ receptor |
| US11046680B1 (en) | 2016-11-16 | 2021-06-29 | Amgen Inc. | Heteroaryl-substituted triazoles as APJ receptor agonists |
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| DK3692015T3 (da) | 2017-10-06 | 2022-11-21 | Univ Johns Hopkins | Hidtil ukendte glutaminantagonister og anvendelser deraf |
| AU2018346597B2 (en) | 2017-10-06 | 2023-07-13 | Forma Therapeutics, Inc. | Inhibiting Ubiquitin Specific Peptidase 30 |
| WO2019089335A1 (fr) | 2017-11-03 | 2019-05-09 | Amgen Inc. | Agonistes de triazole fusionnés du récepteur apj |
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| IL278291B2 (en) | 2018-05-17 | 2023-10-01 | Forma Therapeutics Inc | Condensed bicyclic compounds are useful as ubiquitin-specific peptidase 30 inhibitors |
| EP4218934B1 (fr) | 2018-10-05 | 2025-06-18 | Forma Therapeutics, Inc. | Inhibition de la protéase 30 spécifique de l'ubiquitine (usp30) |
| KR20220054391A (ko) | 2019-08-29 | 2022-05-02 | 리서치 트라이앵글 인스티튜트 | 아펠린 수용체 작용제에 대한 방법 및 용도 |
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| CN120813365A (zh) | 2023-01-03 | 2025-10-17 | 百爱及生物医药公司 | 爱帕琳肽受体激动剂和glp-1受体激动剂的组合疗法用于治疗与体重增加相关的疾病或病况 |
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- 2016-12-09 RU RU2021133849A patent/RU2021133849A/ru unknown
- 2016-12-09 US US15/374,386 patent/US10100059B2/en not_active Ceased
- 2016-12-09 CN CN201680081397.9A patent/CN108602806B/zh not_active Expired - Fee Related
- 2016-12-09 BR BR112018011784A patent/BR112018011784A2/pt not_active Application Discontinuation
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- 2020-10-28 US US17/082,650 patent/US11535630B2/en active Active
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| US20180265518A1 (en) | 2018-09-20 |
| IL259634A (en) | 2018-07-31 |
| AU2016366310A1 (en) | 2018-06-07 |
| US10954247B2 (en) | 2021-03-23 |
| CN108602806A (zh) | 2018-09-28 |
| CA3006205A1 (fr) | 2017-06-15 |
| MX2022002026A (es) | 2022-03-11 |
| US10100059B2 (en) | 2018-10-16 |
| JP2019501899A (ja) | 2019-01-24 |
| PE20190258A1 (es) | 2019-02-25 |
| CO2018005871A2 (es) | 2018-07-10 |
| MX391898B (es) | 2025-03-21 |
| HK1255452A1 (zh) | 2019-08-16 |
| RU2766148C1 (ru) | 2022-02-08 |
| ZA201803301B (en) | 2019-07-31 |
| KR20180090852A (ko) | 2018-08-13 |
| JP2021100934A (ja) | 2021-07-08 |
| US20210070767A1 (en) | 2021-03-11 |
| RU2021133849A (ru) | 2022-03-21 |
| WO2017100558A1 (fr) | 2017-06-15 |
| USRE49594E1 (en) | 2023-08-01 |
| AU2016366310B8 (en) | 2021-06-03 |
| JP7195356B2 (ja) | 2022-12-23 |
| MX2018006979A (es) | 2019-05-16 |
| AU2016366310A8 (en) | 2021-06-03 |
| US11535630B2 (en) | 2022-12-27 |
| US20170166577A1 (en) | 2017-06-15 |
| CN108602806B (zh) | 2022-07-12 |
| EP3386976A1 (fr) | 2018-10-17 |
| BR112018011784A2 (pt) | 2018-12-04 |
| AU2016366310B2 (en) | 2021-05-20 |
| AU2016366310C1 (en) | 2021-09-09 |
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