MA49754B1 - Méthodes de traitement de symptômes de gastroparésie au moyen de velusetrag - Google Patents
Méthodes de traitement de symptômes de gastroparésie au moyen de velusetragInfo
- Publication number
- MA49754B1 MA49754B1 MA49754A MA49754A MA49754B1 MA 49754 B1 MA49754 B1 MA 49754B1 MA 49754 A MA49754 A MA 49754A MA 49754 A MA49754 A MA 49754A MA 49754 B1 MA49754 B1 MA 49754B1
- Authority
- MA
- Morocco
- Prior art keywords
- day
- velusetrag
- methods
- treating gastroparesis
- symptoms
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Otolaryngology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Abstract
La présente invention concerne des méthodes et des compositions pharmaceutiques pour le traitement de tous les symptômes de la gastroparésie chez un patient humain, la méthode comprenant l'administration au patient humain d'environ 0,5 mg/jour à environ 30 mg/jour, environ 0,5 mg/jour à environ 15 mg/jour, environ 0,5 mg/jour à environ 5 mg/jour, ou environ 5 mg/jour, de velusetrag ou d'un sel pharmaceutiquement acceptable de celui-ci.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762539229P | 2017-07-31 | 2017-07-31 | |
| PCT/US2018/044337 WO2019027881A1 (fr) | 2017-07-31 | 2018-07-30 | Méthodes de traitement de symptômes de gastroparésie au moyen de velusetrag |
| EP18756041.2A EP3661518B1 (fr) | 2017-07-31 | 2018-07-30 | Méthodes de traitement de symptômes de gastroparésie au moyen de velusetrag |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MA49754A MA49754A (fr) | 2020-06-10 |
| MA49754B1 true MA49754B1 (fr) | 2024-10-31 |
Family
ID=63245036
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA49754A MA49754B1 (fr) | 2017-07-31 | 2018-07-30 | Méthodes de traitement de symptômes de gastroparésie au moyen de velusetrag |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US11642339B2 (fr) |
| EP (1) | EP3661518B1 (fr) |
| JP (2) | JP7431721B2 (fr) |
| KR (1) | KR102692887B1 (fr) |
| CN (1) | CN110996961A (fr) |
| AU (1) | AU2018309667B2 (fr) |
| BR (1) | BR112020000482A2 (fr) |
| CA (1) | CA3069989C (fr) |
| CL (1) | CL2019003598A1 (fr) |
| DK (1) | DK3661518T3 (fr) |
| EA (1) | EA202090416A1 (fr) |
| ES (1) | ES2991549T3 (fr) |
| FI (1) | FI3661518T3 (fr) |
| HR (1) | HRP20241359T1 (fr) |
| HU (1) | HUE068595T2 (fr) |
| IL (1) | IL272023B2 (fr) |
| LT (1) | LT3661518T (fr) |
| MA (1) | MA49754B1 (fr) |
| MD (1) | MD3661518T2 (fr) |
| MX (1) | MX2020001217A (fr) |
| NZ (1) | NZ760329A (fr) |
| PL (1) | PL3661518T3 (fr) |
| PT (1) | PT3661518T (fr) |
| RS (1) | RS66049B1 (fr) |
| SG (1) | SG11201912266QA (fr) |
| SI (1) | SI3661518T1 (fr) |
| SM (1) | SMT202400447T1 (fr) |
| TW (1) | TW201909896A (fr) |
| UA (1) | UA125596C2 (fr) |
| WO (1) | WO2019027881A1 (fr) |
| ZA (1) | ZA201908495B (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4590303A1 (fr) | 2022-09-20 | 2025-07-30 | Alfasigma S.p.A. | Velusetrag destiné à être utilisé dans le traitement de la pseudo-obstruction intestinale chronique (poic) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI351282B (en) | 2004-04-07 | 2011-11-01 | Theravance Inc | Quinolinone-carboxamide compounds as 5-ht4 recepto |
| US7728006B2 (en) | 2004-04-07 | 2010-06-01 | Theravance, Inc. | Quinolinone-carboxamide compounds as 5-HT4 receptor agonists |
| US8309575B2 (en) | 2004-04-07 | 2012-11-13 | Theravance, Inc. | Quinolinone-carboxamide compounds as 5-HT4 receptor agonists |
| TWI377206B (en) * | 2005-04-06 | 2012-11-21 | Theravance Inc | Crystalline form of a quinolinone-carboxamide compound |
| CA2637214C (fr) | 2006-02-16 | 2014-04-22 | Theravance, Inc. | Procede pour preparer des intermediaires 8-azabicylo[3.2.1]octan-3-one de composes agonistes du recepteur 5-ht4 |
| CA2758321A1 (fr) | 2009-04-13 | 2010-10-21 | Theravance, Inc. | Composes agonistes du recepteur 5-ht4 pour le traitement des troubles cognitifs |
| JP2014525927A (ja) * | 2011-08-18 | 2014-10-02 | シャイアー アーゲー | 治療法に使用される５−ｈｔ４受容体アゴニスト及びｐｄｅ４阻害剤の組合せ |
| PL2747561T3 (pl) * | 2011-08-25 | 2018-11-30 | Evoke Pharma, Inc. | Leczenie objawów związanych z gastroparezą u osobników płci żeńskiej |
-
2018
- 2018-07-30 BR BR112020000482-0A patent/BR112020000482A2/pt not_active Application Discontinuation
- 2018-07-30 FI FIEP18756041.2T patent/FI3661518T3/fi active
- 2018-07-30 WO PCT/US2018/044337 patent/WO2019027881A1/fr not_active Ceased
- 2018-07-30 HU HUE18756041A patent/HUE068595T2/hu unknown
- 2018-07-30 MD MDE20200610T patent/MD3661518T2/ro unknown
- 2018-07-30 RS RS20241118A patent/RS66049B1/sr unknown
- 2018-07-30 CN CN201880047606.7A patent/CN110996961A/zh active Pending
- 2018-07-30 NZ NZ760329A patent/NZ760329A/en unknown
- 2018-07-30 IL IL272023A patent/IL272023B2/en unknown
- 2018-07-30 US US16/048,933 patent/US11642339B2/en active Active
- 2018-07-30 DK DK18756041.2T patent/DK3661518T3/da active
- 2018-07-30 MA MA49754A patent/MA49754B1/fr unknown
- 2018-07-30 EP EP18756041.2A patent/EP3661518B1/fr active Active
- 2018-07-30 AU AU2018309667A patent/AU2018309667B2/en active Active
- 2018-07-30 SG SG11201912266QA patent/SG11201912266QA/en unknown
- 2018-07-30 SI SI201831158T patent/SI3661518T1/sl unknown
- 2018-07-30 EA EA202090416A patent/EA202090416A1/ru unknown
- 2018-07-30 UA UAA202001354A patent/UA125596C2/uk unknown
- 2018-07-30 CA CA3069989A patent/CA3069989C/fr active Active
- 2018-07-30 KR KR1020207005532A patent/KR102692887B1/ko active Active
- 2018-07-30 SM SM20240447T patent/SMT202400447T1/it unknown
- 2018-07-30 JP JP2020505338A patent/JP7431721B2/ja active Active
- 2018-07-30 MX MX2020001217A patent/MX2020001217A/es unknown
- 2018-07-30 HR HRP20241359TT patent/HRP20241359T1/hr unknown
- 2018-07-30 PT PT187560412T patent/PT3661518T/pt unknown
- 2018-07-30 ES ES18756041T patent/ES2991549T3/es active Active
- 2018-07-30 LT LTEPPCT/US2018/044337T patent/LT3661518T/lt unknown
- 2018-07-30 PL PL18756041.2T patent/PL3661518T3/pl unknown
- 2018-07-31 TW TW107126573A patent/TW201909896A/zh unknown
-
2019
- 2019-12-09 CL CL2019003598A patent/CL2019003598A1/es unknown
- 2019-12-19 ZA ZA2019/08495A patent/ZA201908495B/en unknown
-
2022
- 2022-08-26 JP JP2022134792A patent/JP7529952B2/ja active Active
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