MA50906A - Inhibiteurs d'immunoprotéasome - Google Patents

Inhibiteurs d'immunoprotéasome

Info

Publication number
MA50906A
MA50906A MA050906A MA50906A MA50906A MA 50906 A MA50906 A MA 50906A MA 050906 A MA050906 A MA 050906A MA 50906 A MA50906 A MA 50906A MA 50906 A MA50906 A MA 50906A
Authority
MA
Morocco
Prior art keywords
immunoproteasome inhibitors
immunoproteasome
inhibitors
Prior art date
Application number
MA050906A
Other languages
English (en)
Inventor
Kenneth Albert Brameld
David Michael Goldstein
Yan Lou
Timothy Duncan Owens
Original Assignee
Principia Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Principia Biopharma Inc filed Critical Principia Biopharma Inc
Publication of MA50906A publication Critical patent/MA50906A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/69Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MA050906A 2017-11-16 2018-11-14 Inhibiteurs d'immunoprotéasome MA50906A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762587376P 2017-11-16 2017-11-16

Publications (1)

Publication Number Publication Date
MA50906A true MA50906A (fr) 2020-09-23

Family

ID=64746633

Family Applications (1)

Application Number Title Priority Date Filing Date
MA050906A MA50906A (fr) 2017-11-16 2018-11-14 Inhibiteurs d'immunoprotéasome

Country Status (19)

Country Link
US (3) US11225493B2 (fr)
EP (1) EP3710458B1 (fr)
JP (1) JP7277457B2 (fr)
KR (1) KR102625984B1 (fr)
CN (1) CN111491938B (fr)
AU (1) AU2018367515B2 (fr)
CA (1) CA3080949C (fr)
CL (1) CL2020001244A1 (fr)
CO (1) CO2020007150A2 (fr)
EA (1) EA202090900A1 (fr)
IL (1) IL274523B2 (fr)
MA (1) MA50906A (fr)
MX (2) MX2020005046A (fr)
NZ (1) NZ764393A (fr)
PH (1) PH12020550580A1 (fr)
SG (1) SG11202003867SA (fr)
TW (1) TWI837104B (fr)
WO (1) WO2019099582A1 (fr)
ZA (1) ZA202002531B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3571208T (pt) * 2017-01-18 2021-04-13 Principia Biopharma Inc Inibidores do imunoproteassoma
DK3786160T3 (da) 2017-10-27 2022-08-22 Boehringer Ingelheim Int Pyridinderivater og terapeutiske anvendelser deraf som trpc6-inhibitorer
EP3710458B1 (fr) 2017-11-16 2026-03-25 Principia Biopharma Inc. Inhibiteurs d'immunoprotéasome
ES2928787T3 (es) 2017-11-16 2022-11-22 Principia Biopharma Inc Inhibidores del inmunoproteasoma
US20240425529A1 (en) 2021-10-14 2024-12-26 Shouyao Holdings (beijing) Co., Ltd. Boric acid derivative
EP4547676A1 (fr) * 2022-06-30 2025-05-07 Principia Biopharma Inc. Esters boroniques cycliques et leurs utilisations
TWI869142B (zh) * 2022-12-27 2025-01-01 大陸商上海美悦生物科技發展有限公司 三肽環氧酮化合物、藥物組合物及其製備方法和用途

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4107288A (en) 1974-09-18 1978-08-15 Pharmaceutical Society Of Victoria Injectable compositions, nanoparticles useful therein, and process of manufacturing same
US4963655A (en) 1988-05-27 1990-10-16 Mayo Foundation For Medical Education And Research Boron analogs of amino acid/peptide protease inhibitors
US5145684A (en) 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
IL111175A0 (en) 1993-10-07 1994-12-29 Du Pont Merck Pharma Electrophilic peptide analogs as inhibitors of trypsin-like serine proteases and pharmaceutical compositions containing them
US6083903A (en) 1994-10-28 2000-07-04 Leukosite, Inc. Boronic ester and acid compounds, synthesis and uses
US7576206B2 (en) * 2003-08-14 2009-08-18 Cephalon, Inc. Proteasome inhibitors and methods of using the same
AU2005216970B2 (en) 2004-02-23 2011-07-07 Trustees Of Tufts College Inhibitors of dipeptidylpeptidase IV for regulating glucose metabolism
EP2542238B1 (fr) * 2010-03-01 2015-08-12 Onyx Therapeutics, Inc. Composés pour inhibition de l'immunoprotéasome
SG11201403254QA (en) 2011-12-22 2014-07-30 Ares Trading Sa Alpha-amino boronic acid derivatives, selective immunoproteasome inhibitors
WO2015195950A1 (fr) 2014-06-20 2015-12-23 Principia Biophamram Inc. Inhibiteurs de lmp7
CN107001391B (zh) * 2014-10-01 2020-11-27 默克专利股份公司 硼酸衍生物
CN106588965A (zh) * 2015-10-15 2017-04-26 北京大学 脲拟肽硼酸化合物及其药物组合物、制备方法和用途
PT3571208T (pt) * 2017-01-18 2021-04-13 Principia Biopharma Inc Inibidores do imunoproteassoma
ES2928787T3 (es) 2017-11-16 2022-11-22 Principia Biopharma Inc Inhibidores del inmunoproteasoma
EP3710458B1 (fr) 2017-11-16 2026-03-25 Principia Biopharma Inc. Inhibiteurs d'immunoprotéasome

Also Published As

Publication number Publication date
IL274523A (en) 2020-06-30
CA3080949A1 (fr) 2019-05-23
CA3080949C (fr) 2024-04-16
EP3710458B1 (fr) 2026-03-25
AU2018367515B2 (en) 2023-04-27
US20220073538A1 (en) 2022-03-10
SG11202003867SA (en) 2020-05-28
IL274523B2 (en) 2024-02-01
US11827656B2 (en) 2023-11-28
CN111491938B (zh) 2024-05-24
IL274523B1 (en) 2023-10-01
CL2020001244A1 (es) 2020-08-21
EA202090900A1 (ru) 2020-10-02
KR102625984B1 (ko) 2024-01-18
TWI837104B (zh) 2024-04-01
WO2019099582A1 (fr) 2019-05-23
BR112020009516A2 (pt) 2020-11-03
CO2020007150A2 (es) 2020-06-19
NZ764393A (en) 2023-11-24
JP2021503471A (ja) 2021-02-12
CN111491938A (zh) 2020-08-04
US11225493B2 (en) 2022-01-18
ZA202002531B (en) 2023-10-25
US12312370B2 (en) 2025-05-27
US20200277312A1 (en) 2020-09-03
MX2020005046A (es) 2020-08-20
TW201930264A (zh) 2019-08-01
US20240199655A1 (en) 2024-06-20
KR20200085868A (ko) 2020-07-15
EP3710458A1 (fr) 2020-09-23
MX2022012825A (es) 2022-11-07
AU2018367515A1 (en) 2020-05-14
PH12020550580A1 (en) 2021-04-26
JP7277457B2 (ja) 2023-05-19

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