MA53075A - Dérivés d'oxadiazolopyridine à substitution benzyle, (pyridin-3-yl)méthyle ou (pyridin-4-yl)méthyle utilisés en tant qu'inhibiteurs de la ghréline o-acyltransférase (goat) - Google Patents
Dérivés d'oxadiazolopyridine à substitution benzyle, (pyridin-3-yl)méthyle ou (pyridin-4-yl)méthyle utilisés en tant qu'inhibiteurs de la ghréline o-acyltransférase (goat)Info
- Publication number
- MA53075A MA53075A MA053075A MA53075A MA53075A MA 53075 A MA53075 A MA 53075A MA 053075 A MA053075 A MA 053075A MA 53075 A MA53075 A MA 53075A MA 53075 A MA53075 A MA 53075A
- Authority
- MA
- Morocco
- Prior art keywords
- pyridin
- methyl
- ghrelin
- acyltransferase
- goat
- Prior art date
Links
- -1 (PYRIDIN-3-YL) METHYL Chemical class 0.000 title 2
- 102100038752 Ghrelin O-acyltransferase Human genes 0.000 title 2
- 101710205760 Ghrelin O-acyltransferase Proteins 0.000 title 2
- SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical group [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- RWXCVESEMJNNMF-UHFFFAOYSA-N oxadiazolo[5,4-b]pyridine Chemical class C1=CN=C2ON=NC2=C1 RWXCVESEMJNNMF-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Obesity (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18154824 | 2018-02-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA53075A true MA53075A (fr) | 2021-05-12 |
Family
ID=61157050
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA053075A MA53075A (fr) | 2018-02-02 | 2019-01-28 | Dérivés d'oxadiazolopyridine à substitution benzyle, (pyridin-3-yl)méthyle ou (pyridin-4-yl)méthyle utilisés en tant qu'inhibiteurs de la ghréline o-acyltransférase (goat) |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US11254688B2 (fr) |
| EP (1) | EP3746451B1 (fr) |
| JP (1) | JP7015396B2 (fr) |
| KR (1) | KR20200116978A (fr) |
| CN (1) | CN111655700B (fr) |
| AU (1) | AU2019215707A1 (fr) |
| BR (1) | BR112020013082A2 (fr) |
| CA (1) | CA3087826A1 (fr) |
| CL (1) | CL2020001907A1 (fr) |
| CO (1) | CO2020009299A2 (fr) |
| CR (1) | CR20200332A (fr) |
| EA (1) | EA202091805A1 (fr) |
| EC (1) | ECSP20050785A (fr) |
| IL (1) | IL276136A (fr) |
| JO (1) | JOP20200190A1 (fr) |
| MA (1) | MA53075A (fr) |
| MX (1) | MX2020008053A (fr) |
| PE (1) | PE20210174A1 (fr) |
| PH (1) | PH12020551168A1 (fr) |
| SG (1) | SG11202006125VA (fr) |
| WO (1) | WO2019149657A1 (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6651054B2 (ja) * | 2016-08-05 | 2020-02-19 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | グレリンo−アシルトランスフェラーゼ(goat)阻害薬として使用するためのオキサジアゾロピリジン誘導体 |
| JP7083397B2 (ja) | 2018-02-02 | 2022-06-10 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | グレリンo-アシルトランスフェラーゼ(goat)阻害剤として使用するためのトリアゾロピリミジン誘導体 |
| WO2019149658A1 (fr) * | 2018-02-02 | 2019-08-08 | Boehringer Ingelheim International Gmbh | Dérivés d'oxadiazolopyridine à substitution pyrazole et indazole destinés à être utilisés en tant qu'inhibiteurs de la ghréline o-acyl transférase (goat) |
| CA3087826A1 (fr) | 2018-02-02 | 2019-08-08 | Boehringer Ingelheim International Gmbh | Derives d'oxadiazolopyridine a substitution benzyle, (pyridin-3-yl)methyle ou (pyridin-4-yl)methyle utilises en tant qu'inhibiteurs de la ghreline o-acyltransferase (goat) |
| PH12022552277A1 (en) | 2020-02-28 | 2024-03-04 | Kallyope Inc | Gpr40 agonists |
| PL4153600T3 (pl) | 2020-05-22 | 2024-12-16 | Boehringer Ingelheim International Gmbh | Sposób ciągły wytwarzania 7-amino-5-metylo-[1,2,5]oksadiazolo[3,4- b]pirydynokarboksylanu alkilu |
| WO2021233882A1 (fr) | 2020-05-22 | 2021-11-25 | Boehringer Ingelheim International Gmbh | Procédé de fabrication de 7-amino-5-méthyl- [1,2,5] oxadiazolo [3,4-b] pyridine-carboxylate d'alkyle |
| CA3241217A1 (fr) * | 2021-12-16 | 2023-06-22 | Jian Jin | Composes heterocycliques en tant qu'agonistes polarises 5ht2a |
| CN114426516B (zh) * | 2022-02-16 | 2022-11-04 | 安徽有吉医药科技有限公司 | 一种2-氨基-3-溴吡啶的制备方法 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004082383A1 (fr) | 2003-03-17 | 2004-09-30 | Basf Aktiengesellschaft | Utilisation de triazolopyrimidines pour combattre les nematodoses de vegetaux |
| CA2657660A1 (fr) * | 2006-07-12 | 2008-01-17 | Merck & Co., Inc. | Pyrazoles substitues servant d'antagonistes des recepteurs de la ghreline |
| JP6017754B2 (ja) | 2007-02-15 | 2016-11-02 | インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation | グルカゴン/glp−1受容体コアゴニスト |
| US8084454B2 (en) | 2007-04-11 | 2011-12-27 | Canbas Co., Ltd. | Compounds with anti-cancer activity |
| CA2687611A1 (fr) | 2007-05-24 | 2008-11-27 | Bayer Schering Pharma Aktiengesellschaft | Nouveaux derives de quinoleine et de quinazoline substituee par un sulphoximine et de quinazoline en tant qu'inhibiteurs de kinase |
| DK2158214T3 (da) | 2007-06-15 | 2011-12-05 | Zealand Pharma As | Glukagonanaloger |
| FR2934058B1 (fr) | 2008-07-15 | 2010-09-24 | Centre Nat Rech Scient | Dispositif de projection interferometrique a trois ouvertures pour produire une tache constituee de structures fines |
| FR2933989B1 (fr) | 2008-07-16 | 2013-03-08 | Commissariat Energie Atomique | Procede de purification de microorganismes presents dans des echantillons liquides |
| FR2933975B1 (fr) | 2008-07-17 | 2011-02-18 | Servier Lab | Nouveau procede de preparation de benzocyclobutenes fonctionnalises,et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable. |
| WO2010070252A1 (fr) | 2008-12-15 | 2010-06-24 | Zealand Pharma A/S | Analogues du glucagon |
| NZ593813A (en) | 2008-12-15 | 2013-02-22 | Zealand Pharma As | Glucagon analogues |
| JP5635531B2 (ja) | 2008-12-15 | 2014-12-03 | ジーランド ファーマ アクティーゼルスカブ | グルカゴン類似体 |
| JP5635529B2 (ja) | 2008-12-15 | 2014-12-03 | ジーランド ファーマ アクティーゼルスカブ | グルカゴン類似体 |
| ME02220B (me) | 2009-07-13 | 2016-02-20 | Zealand Pharma As | Analozi acilovanog glukagona |
| US20110078154A1 (en) | 2009-09-28 | 2011-03-31 | Accenture Global Services Gmbh | Recruitment screening tool |
| AR081975A1 (es) | 2010-06-23 | 2012-10-31 | Zealand Pharma As | Analogos de glucagon |
| EP2585482B1 (fr) | 2010-06-24 | 2019-03-27 | Zealand Pharma A/S | Analogues de glucagon |
| SG11201403377QA (en) | 2011-12-23 | 2014-07-30 | Zealand Pharma As | Glucagon analogues |
| JP6106179B2 (ja) | 2012-02-24 | 2017-03-29 | 武田薬品工業株式会社 | 芳香環化合物 |
| WO2013192388A1 (fr) | 2012-06-20 | 2013-12-27 | University Of Virginia Patent Foundation | Compositions et procédés pour réguler l'homéostasie du glucose et l'action de l'insuline |
| TWI608013B (zh) | 2012-09-17 | 2017-12-11 | 西蘭製藥公司 | 升糖素類似物 |
| UA118034C2 (uk) | 2013-11-14 | 2018-11-12 | Елі Ліллі Енд Компані | Заміщений піперидилетилпіримідин як інгібітор грелін-o-ацилтрансферази |
| EP3193939A4 (fr) * | 2014-09-17 | 2018-10-24 | The Regents of The University of California | Petits inhibiteurs lipopeptidomimétiques de la ghréline o-acyl transférase |
| WO2016123275A1 (fr) | 2015-01-30 | 2016-08-04 | Boehringer Ingelheim International Gmbh | Inhibiteurs de l'aldostérone synthase |
| AR104672A1 (es) * | 2015-04-15 | 2017-08-09 | Lilly Co Eli | Inhibidores de grelina o-aciltransferasa |
| AR104673A1 (es) * | 2015-04-15 | 2017-08-09 | Lilly Co Eli | Inhibidores de grelina o-aciltransferasa |
| WO2017070680A1 (fr) | 2015-10-22 | 2017-04-27 | Cavion Llc | Procédés pour traiter le syndrome d'angelman et des troubles associés |
| JP6651054B2 (ja) * | 2016-08-05 | 2020-02-19 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | グレリンo−アシルトランスフェラーゼ(goat)阻害薬として使用するためのオキサジアゾロピリジン誘導体 |
| NZ750126A (en) * | 2016-08-11 | 2022-07-01 | Cellix Bio Private Ltd | Compositions and methods for the treatment of irritable bowel syndrome |
| US10988487B2 (en) | 2016-08-29 | 2021-04-27 | Merck Sharp & Dohme Corp. | Substituted n′-hydroxycarbamimidoyl-1,2,5-oxadiazole compounds as indoleamine 2,3-dioxygenase (IDO) inhibitors |
| JP7083397B2 (ja) | 2018-02-02 | 2022-06-10 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | グレリンo-アシルトランスフェラーゼ(goat)阻害剤として使用するためのトリアゾロピリミジン誘導体 |
| CR20200331A (es) | 2018-02-02 | 2020-09-03 | Boehringer Ingelheim Int | Derivados de oxadiazolopirisdina sustituidos con heterociclilo para usar como inhibidores de ghrelin o-aciltrasferasa (goat) |
| CA3087826A1 (fr) | 2018-02-02 | 2019-08-08 | Boehringer Ingelheim International Gmbh | Derives d'oxadiazolopyridine a substitution benzyle, (pyridin-3-yl)methyle ou (pyridin-4-yl)methyle utilises en tant qu'inhibiteurs de la ghreline o-acyltransferase (goat) |
| WO2019149658A1 (fr) | 2018-02-02 | 2019-08-08 | Boehringer Ingelheim International Gmbh | Dérivés d'oxadiazolopyridine à substitution pyrazole et indazole destinés à être utilisés en tant qu'inhibiteurs de la ghréline o-acyl transférase (goat) |
-
2019
- 2019-01-28 CA CA3087826A patent/CA3087826A1/fr not_active Abandoned
- 2019-01-28 MA MA053075A patent/MA53075A/fr unknown
- 2019-01-28 JO JOP/2020/0190A patent/JOP20200190A1/ar unknown
- 2019-01-28 WO PCT/EP2019/051989 patent/WO2019149657A1/fr not_active Ceased
- 2019-01-28 PE PE2020001161A patent/PE20210174A1/es unknown
- 2019-01-28 US US16/966,483 patent/US11254688B2/en active Active
- 2019-01-28 AU AU2019215707A patent/AU2019215707A1/en not_active Abandoned
- 2019-01-28 EP EP19702246.0A patent/EP3746451B1/fr active Active
- 2019-01-28 CN CN201980010416.2A patent/CN111655700B/zh active Active
- 2019-01-28 SG SG11202006125VA patent/SG11202006125VA/en unknown
- 2019-01-28 JP JP2020541873A patent/JP7015396B2/ja active Active
- 2019-01-28 MX MX2020008053A patent/MX2020008053A/es unknown
- 2019-01-28 KR KR1020207025417A patent/KR20200116978A/ko not_active Withdrawn
- 2019-01-28 EA EA202091805A patent/EA202091805A1/ru unknown
- 2019-01-28 CR CR20200332A patent/CR20200332A/es unknown
- 2019-01-28 BR BR112020013082-6A patent/BR112020013082A2/pt not_active Application Discontinuation
-
2020
- 2020-07-19 IL IL276136A patent/IL276136A/en unknown
- 2020-07-21 CL CL2020001907A patent/CL2020001907A1/es unknown
- 2020-07-28 CO CONC2020/0009299A patent/CO2020009299A2/es unknown
- 2020-07-31 PH PH12020551168A patent/PH12020551168A1/en unknown
- 2020-08-24 EC ECSENADI202050785A patent/ECSP20050785A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP3746451B1 (fr) | 2023-07-12 |
| US20210053985A1 (en) | 2021-02-25 |
| JOP20200190A1 (ar) | 2020-07-29 |
| BR112020013082A2 (pt) | 2020-12-01 |
| US11254688B2 (en) | 2022-02-22 |
| CL2020001907A1 (es) | 2020-10-30 |
| PH12020551168A1 (en) | 2021-05-31 |
| CR20200332A (es) | 2020-09-03 |
| MX2020008053A (es) | 2020-09-07 |
| CN111655700B (zh) | 2023-07-18 |
| PE20210174A1 (es) | 2021-01-29 |
| WO2019149657A1 (fr) | 2019-08-08 |
| SG11202006125VA (en) | 2020-07-29 |
| CO2020009299A2 (es) | 2020-08-21 |
| CA3087826A1 (fr) | 2019-08-08 |
| AU2019215707A1 (en) | 2020-07-09 |
| KR20200116978A (ko) | 2020-10-13 |
| JP7015396B2 (ja) | 2022-02-15 |
| ECSP20050785A (es) | 2020-09-30 |
| IL276136A (en) | 2020-09-30 |
| EA202091805A1 (ru) | 2020-12-16 |
| JP2021512113A (ja) | 2021-05-13 |
| EP3746451A1 (fr) | 2020-12-09 |
| CN111655700A (zh) | 2020-09-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MA53075A (fr) | Dérivés d'oxadiazolopyridine à substitution benzyle, (pyridin-3-yl)méthyle ou (pyridin-4-yl)méthyle utilisés en tant qu'inhibiteurs de la ghréline o-acyltransférase (goat) | |
| MA51774A (fr) | Dérivés de triazolopyrimidine destinés à être utilisés en tant qu'inhibiteurs de la ghréline o-acyltransférase (goat) | |
| MA53074A (fr) | Dérivés d'oxadiazolopyridine à substitution hétérocyclyle utilisés en tant qu'inhibiteurs de la ghréline o-acyltransférase (goat) | |
| EP3873468A4 (fr) | 2-amino-n-phényl-nicotinamides utilisés en tant qu'inhibiteurs de nav1.8 | |
| EP3768671A4 (fr) | Dérivés d'imidazolidine-2-one substitués en tant qu'inhibiteurs de prmt5 | |
| MA53487A (fr) | Composés pyrazolo[3,4-b]pyridine utilisés en tant qu'inhibiteurs de kinases tam et met | |
| MA51610A (fr) | Dérivés d'imidazole fusionnés utilisés en tant qu'inhibiteurs d'il-17 | |
| MA53377A (fr) | Composés de pyridin-2-one utiles en tant qu'antagonistes de smarca2 | |
| MA51846A (fr) | Composés hétérocycliques utilisés en tant qu'inhibiteurs de kinases | |
| CY1124858T1 (el) | Σαλικυλαμιδια σπειροεπτανιου και σχετικες ενωσεις ως αναστολεις του rock | |
| EP3873905A4 (fr) | Composés, compositions pharmaceutiques, procédés de préparation de composés et leur utilisation en tant qu'inhibiteurs de kinase atr | |
| MA46531A (fr) | Dérivés d'azétidine ou de cyclobutane 1,3-disubstitués utilisés comme inhibiteurs de la prostaglandine d synthase hématopoïétique (h-pgds) | |
| MA53675A (fr) | Composés substitués de pyrazolo[1,5-a]pyridine en tant qu'inhibiteurs de la kinase ret | |
| EP3953360C0 (fr) | Composés hétérocycliques en tant qu' inhibiteurs de la lipase monoacylglycerol (magl) | |
| EP3706749A4 (fr) | Composés macrocycliques en tant qu'inhibiteurs de kinase trk et leurs utilisations | |
| MA47591A (fr) | Dérivés de [1,2,4]-triazolo [1,5-a]-pyrimidinyle substitués par de la pipéridine, de la morpholine ou de la pipérazine utilisés en tant qu'inhibiteurs d'oga | |
| EP3952865A4 (fr) | Composés hétérocycliques en tant qu'inhibiteurs de kinase pour des utilisations thérapeutiques | |
| MX390625B (es) | Inhibidores selectivos de jak1. | |
| EA202090368A1 (ru) | Соединения-ингибиторы рецептора лизофосфатидной кислоты 1 (lpar1) | |
| EA201991021A1 (ru) | Соединения конденсированных бициклических пиридинов и их применение в качестве модуляторов ampa-рецептора | |
| MA54551A (fr) | Composés d'imidazopyridazine et d'imidazopyridine utilisés en tant qu'inhibiteurs de la kinase 2 de type récepteur de l'activine | |
| MA50356A (fr) | Composés bicycliques destinés à être utilisés en tant qu'inhibiteurs de la kinase rip1 | |
| MA53432A (fr) | Imidazo[1,2-b]pyridazines utilisées en tant qu'inhibiteurs de trk | |
| EP3972588A4 (fr) | Dérivés d'imidazole, compositions et procédés en tant qu'antagonistes de l'orexine | |
| MA55517A (fr) | Composés macrocycliques utilisés en tant qu'agonistes sting |