MC1601A1 - Nouveaux derives de thiazolidine - Google Patents

Nouveaux derives de thiazolidine

Info

Publication number
MC1601A1
MC1601A1 MC841709A MC1709A MC1601A1 MC 1601 A1 MC1601 A1 MC 1601A1 MC 841709 A MC841709 A MC 841709A MC 1709 A MC1709 A MC 1709A MC 1601 A1 MC1601 A1 MC 1601A1
Authority
MC
Monaco
Prior art keywords
fluoro
benzopyran
thiazolidine
dihydro
dioxospiro
Prior art date
Application number
MC841709A
Other languages
English (en)
French (fr)
Inventor
Heinz Hasler
Fernand Schneider
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MC1601A1 publication Critical patent/MC1601A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/08—Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
MC841709A 1983-06-23 1984-06-20 Nouveaux derives de thiazolidine MC1601A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH343283 1983-06-23
CH186084 1984-04-13

Publications (1)

Publication Number Publication Date
MC1601A1 true MC1601A1 (fr) 1985-05-09

Family

ID=25688868

Family Applications (1)

Application Number Title Priority Date Filing Date
MC841709A MC1601A1 (fr) 1983-06-23 1984-06-20 Nouveaux derives de thiazolidine

Country Status (11)

Country Link
US (1) US4587256A (da)
EP (1) EP0129747A3 (da)
AU (1) AU2947784A (da)
DK (1) DK277484A (da)
ES (4) ES8602820A1 (da)
FI (1) FI842327L (da)
HU (1) HUT34509A (da)
IL (1) IL72139A0 (da)
MC (1) MC1601A1 (da)
NO (1) NO842515L (da)
PT (1) PT78778B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4537892A (en) * 1983-09-14 1985-08-27 Alcon Laboratories, Inc. Spiro-tricyclicaromatic succinimide derivatives as inhibitors of aldose reductase
JPH06772B2 (ja) * 1984-07-09 1994-01-05 鐘淵化学工業株式会社 ３―（４―フルオロフエノキシ）プロピオニトリルを用いる６―フルオロ―４―クロマノンの製造法
JPS61200991A (ja) * 1985-03-04 1986-09-05 Sanwa Kagaku Kenkyusho:Kk スピロ―３―ヘテロアゾリジン化合物、その製法及びそれを有効成分とする糖尿病合併症の予防及び治療剤
AU617541B2 (en) * 1988-10-20 1991-11-28 Wyeth Spiro-isoquinoline-pyrrolidine tetrones and analogs thereof useful as aldose reductase inhibitors
US6756360B1 (en) 1998-12-24 2004-06-29 Metabasis Therapeutics, Inc. Combination of FBPase inhibitors and insulin sensitizers for the treatment of diabetes
AU784370B2 (en) * 1999-12-22 2006-03-23 Metabasis Therapeutics, Inc. Novel bisamidate phosphonate prodrugs
US7563774B2 (en) 2000-06-29 2009-07-21 Metabasis Therapeutics, Inc. Combination of FBPase inhibitors and antidiabetic agents useful for the treatment of diabetes
US6812355B2 (en) 2002-10-22 2004-11-02 Sekhsaria Chemicals Limited Process for the manufacture of citalopram hydrobromide from 5-bromophthalide
BRPI0510394A (pt) * 2004-05-24 2007-11-13 Amgen Inc inibidores de 11-beta-hidroxiesteróide desidrogenase tipo 1
US8686011B2 (en) 2004-05-24 2014-04-01 Amgen Inc. Inhibitors of 11-β-hydroxy steroid dehydrogenase type 1
JP2008510018A (ja) * 2004-08-18 2008-04-03 メタバシス・セラピューティクス・インコーポレイテッド フルクトース−１，６−ビスホスファターゼの新規チアゾール阻害物質
US7828840B2 (en) * 2007-11-15 2010-11-09 Med Institute, Inc. Medical devices and methods for local delivery of angiotensin II type 2 receptor antagonists
CN115322208B (zh) * 2021-05-10 2023-04-11 中国药科大学 2-氨基噻唑类衍生物及其制备方法和医药用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4210756A (en) * 1976-10-18 1980-07-01 Pfizer Inc. Tetrahydroquinoline hydantoins for chronic diabetic complications
US4200642A (en) * 1978-08-21 1980-04-29 Pfizer Inc. Spiro-oxazolidindiones
US4226875A (en) * 1979-04-02 1980-10-07 Pfizer Inc. Novel spiro-oxazolidinediones
US4248882A (en) * 1980-02-12 1981-02-03 Pfizer Inc. Treating diabetes-associated complications with hydantoin amines

Also Published As

Publication number Publication date
HUT34509A (en) 1985-03-28
ES533624A0 (es) 1985-12-16
FI842327A0 (fi) 1984-06-08
AU2947784A (en) 1985-01-03
FI842327A7 (fi) 1984-12-24
NO842515L (no) 1984-12-27
US4587256A (en) 1986-05-06
FI842327L (fi) 1984-12-24
DK277484A (da) 1984-12-24
PT78778A (en) 1984-07-01
DK277484D0 (da) 1984-06-04
EP0129747A2 (de) 1985-01-02
PT78778B (en) 1986-09-15
IL72139A0 (en) 1984-10-31
ES541705A0 (es) 1985-12-01
ES541708A0 (es) 1985-12-01
ES8602820A1 (es) 1985-12-16
ES541707A0 (es) 1985-12-01
EP0129747A3 (de) 1985-09-25
ES8602716A1 (es) 1985-12-01
ES8602719A1 (es) 1985-12-01
ES8602718A1 (es) 1985-12-01

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